Patents Assigned to Bayer HealthCare, LLC
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Patent number: 10512720Abstract: A syringe includes a barrel having a distal end, a proximal end, and a sidewall extending therebetween along a longitudinal axis. At least one engagement member protrudes from a terminal portion of the sidewall in a proximal direction along the longitudinal axis. The at least one engagement member tapers axially in a direction from the distal end toward the proximal end. The at least one engagement member is configured for engagement with a locking mechanism of a fluid injector to releasably lock the syringe with the fluid injector. A taper of the at least one engagement member is configured to rotationally guide the syringe into alignment with the locking mechanism and axially eject the syringe upon rotation of the syringe. The locking mechanism operatively engages the at least one engagement member regardless of an orientation of the syringe about the longitudinal axis relative to the injector.Type: GrantFiled: November 30, 2015Date of Patent: December 24, 2019Assignee: BAYER HEALTHCARE LLCInventors: Kevin P. Cowan, Barry L. Tucker, Arthur E. Uber, III, Edward J. Rhinehart, James R. Neill, Glen P. Williams, Michael A. Spohn
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Patent number: 10512721Abstract: A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engagable with the piston regardless of a rotational orientation of the piston relative to the plunger.Type: GrantFiled: October 26, 2016Date of Patent: December 24, 2019Assignee: BAYER HEALTHCARE LLCInventors: Michael J. Swantner, Richard A. Seman, Barry L. Tucker, Arthur E. Uber, III, Kevin P. Cowan, James A. Dedig, Christopher D. Capone, Jaroslaw Wlodarczyk
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Publication number: 20190381008Abstract: Methods for treatment of wAMD with an active CNV lesion of less than 50% of the total lesion size and pharmaceutical compositions for the use therein are disclosed.Type: ApplicationFiled: June 26, 2019Publication date: December 19, 2019Applicant: Bayer HealthCare LLCInventors: Oliver ZEITZ, Olaf SOWADE, Haiyan WU
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Patent number: 10507319Abstract: A multi-use disposable set (MUDS) has at least one syringe having a proximal end and a distal end spaced apart from the proximal end along a longitudinal axis. The MUDS further has a plunger reciprocally movable within a syringe interior between the proximal end and the distal end. A manifold is in fluid communication with the distal end of the at least one syringe. At least one valve is in fluid communication with the syringe interior. The at least one valve is operable between a filling position for filling the syringe interior with fluid and a delivery position for delivering the fluid from the syringe interior. At least one connection port is in fluid communication with the manifold and the syringe interior when the at least one valve is in the delivery position. A multi-fluid delivery system having the medical convector and MUDS is also provided. Various features of the MUDS system are also described.Type: GrantFiled: January 7, 2016Date of Patent: December 17, 2019Assignee: BAYER HEALTHCARE LLCInventors: John A. Haury, Michael Swantner, Richard Sokolov, Benjamin James Cullen, Alison Ruth Norcott, Ernesto Hueso Monis, Kamman Law, Mark Silvio Profaca, Patrick Spence, Michael A. Spohn, Justin Angert
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Patent number: 10507003Abstract: Described is an in-scan phantom for use during an imaging procedure. The phantom can include at least one measuring insert and/or at least one measured insert. The measuring insert may have radiation detecting capabilities while the measured insert may include a radioactive material. Also described is an imaging modality system that includes an imaging modality and an in-scan phantom as well as methods of using the in-scan phantom for imaging a patient or performing a scout scan.Type: GrantFiled: February 26, 2016Date of Patent: December 17, 2019Assignee: BAYER HEALTHCARE LLCInventors: Arthur E. Uber, III, Kevin P. Cowan, David M. Griffiths, Ivana Kingston, Dzmitry Liushtyk, Matthew Hoiko, Roey Flor, Robert Redmond, Henry Hernaez, Sridhar Balasubramanian
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Publication number: 20190367256Abstract: The present disclosure relates to, inter alia, a method of making a whipped formulation and the formulation. The method comprises: selecting an amount of a gas propellant co-mingled with one or more active agents. The gas propellant is dispersed in the formulation, and the formulation is filled under pressure into a package, which may be pressurized. The package has a selected amount of pressure (“pre-gas or cut-bag pressure”). The pressure maintains the gas propellant dispersed in the formulation and the pressurized package is under sufficient pressure such that the formulation may be expelled as a whipped formulation upon application of external force on said formulation in said package. The whipped formulation is characterized by providing a desired sensory impact to a user.Type: ApplicationFiled: May 11, 2017Publication date: December 5, 2019Applicants: Bayer Healthcare LLC, Formulated Solutions, LLCInventors: Stephen Baldwin, Scott Carpenter, Heidi Graham, Nanhye Kim, Tom Meyer, David Reynolds, Jerry Vancleave, Eric Dann, Thomas Dann, Renee Nelson, Brian Dann
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Publication number: 20190370513Abstract: A reader system for reading information on at least one identification tag associated with a syringe connected to a fluid injector has a detector and a background screen spaced apart from the detector such that at least one of the at least one identification tags is positioned in an optical path between the detector and the background screen when the syringe is connected to the fluid injector. The reader system further has an illumination system configured for illuminating at least a portion of the background screen. The detector is configured for detecting and decoding the at least one identification tag.Type: ApplicationFiled: February 22, 2018Publication date: December 5, 2019Applicant: BAYER HEALTHCARE LLCInventors: CHRISTOPHER CAPONE, JAROSLAW WLODARCZYK
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Publication number: 20190350865Abstract: The present disclosure provides for suspension-based pharmaceutical formulations for cold and flu medications, specifically suspension formulations and soft gel capsule dosage forms having reduced size. The present disclosure also provides methods of preparing the suspensions and soft gel capsule dosage forms.Type: ApplicationFiled: May 13, 2019Publication date: November 21, 2019Applicant: BAYER HEALTHCARE LLCInventors: JAVIER ZUMETA PEREZ, BLANCA ALVAREZ MALUENDA, MARIA PILAR SANZ SAIZ, MARIA ELENA IGLESIAS PIÑEIRO, ANTHONY BELL, REINHARD WALTER
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Patent number: 10478558Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.Type: GrantFiled: December 12, 2016Date of Patent: November 19, 2019Assignee: BAYER HEALTHCARE LLCInventors: Martin J. Uram, Michael J. Yanniello, Barry L. Tucker, David A. Mishler, Edward J. Rhinehart, Mark Trocki, Arthur E. Uber, III, Kevin P. Cowan, John A. Brosovich
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Patent number: 10463782Abstract: A system has a parameter generation system that includes a processor, an input system and a memory system in which an algorithm is stored. Upon execution by the processor, the algorithm is used to determine parameters of at least one phase of an injection procedure to be performed on a patient based at least in part upon the type of injection procedure selected via the input system. The volume of a pharmaceutical to be delivered to the patient during the injection procedure is determined at least in part on the basis of the concentration of a contrast enhancing agent contained in the pharmaceutical and at least in part on the basis of a function that depends upon and varies with a parameter of the patient such as the weight, the body mass index, the body surface area or the cardiac output of the patient.Type: GrantFiled: March 16, 2016Date of Patent: November 5, 2019Assignee: BAYER HEALTHCARE LLCInventors: John F. Kalafut, Larry McCutchan
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Patent number: 10441716Abstract: The control device is used to control delivery of fluids from a multi-fluid delivery system during a medical injection procedure. The fluid delivery system includes an injector used to deliver injection fluids to a patient. The control device is operatively associated with the injector for controlling discrete flow rates of injection fluids delivered to the patient. The control device includes first and second actuators associated with the manual control device, and an electronic substrate disposed within the manual control device and having a conductive pattern. The first actuator is operatively associated with the conductive pattern. The conductive pattern includes a plurality of predetermined digital values corresponding to discrete flow rates of injection fluids to be delivered by the injector.Type: GrantFiled: January 8, 2018Date of Patent: October 15, 2019Assignee: BAYER HEALTHCARE LLCInventors: Ralph H. Schriver, Thomas P. Joyce, Michael Riley, William D. Barlow
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Patent number: 10441775Abstract: A bolus control device for use with an injection device includes a valve body having a proximal end opposite a distal end. The valve body defines a fluid channel therethrough to allow a passage of medical fluid from the proximal end to the distal end. A connector at the proximal end and is configured for connecting to a fluid inlet line. A connector subassembly at the distal end and is configured for connecting to a fluid outlet line. A compressible check valve is disposed within the fluid channel, such that the compressible check valve is adjustable to control a cracking pressure at which the compressible check valve closes.Type: GrantFiled: April 29, 2014Date of Patent: October 15, 2019Assignee: BAYER HEALTHCARE LLCInventors: Ralph H. Schriver, James A. Dedig
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Patent number: 10434249Abstract: A syringe includes a body and a plunger movably disposed within the body. The syringe may be used with an injector including a drive member. The drive member preferably includes at least one pin adapted to form a retractable abutting connection with an interior of a plunger to enable the drive member to retract the plunger with the body of the syringe.Type: GrantFiled: October 28, 2016Date of Patent: October 8, 2019Assignee: Bayer HealthCare LLCInventors: Kevin P. Cowan, John H. Haury, Jared E. Neff
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Patent number: 10438348Abstract: Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generating a suitable patient model used to make such an estimate, to approaches for estimating patient dose by interpolating the results of multiple simulations, and to approaches for a service provider to host a dose estimation service made available to multiple CT scan providers.Type: GrantFiled: January 16, 2017Date of Patent: October 8, 2019Assignee: BAYER HEALTHCARE LLCInventors: Gregory Couch, James Couch
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Patent number: 10420902Abstract: A fluid injection system and a fluid verification system for confirming that a syringe, containing a fluid for injection, is fully filled with fluid and neither has free space (i.e., air) near the distal end thereof when the syringe is provided in an upright position nor contains air bubbles. Imaging processing techniques and systems are also provided to determine various injection parameters and to verify the type and certain properties of fluid that is present within a syringe.Type: GrantFiled: August 29, 2016Date of Patent: September 24, 2019Assignee: BAYER HEALTHCARE LLCInventors: Kevin P. Cowan, Michael A. Spohn, Michael McDermott, Herbert M. Grubic, Henry Phalen
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Publication number: 20190282463Abstract: The present disclosure relates to, inter alia, a formulation in a package. The formulation comprises one or more active agents and is co-mingled with a whipping agent prior to being filled under pressure into the package. The whipping agent is added in sufficient amounts to be dispersed in the formulation. The pressurized package is under sufficient pressure suitable to maintain the whipping agent dispersed in the formulation; and the pressurized package is under sufficient pressure to expel the formulation as a whipped formulation upon application of external force on the formulation in the package.Type: ApplicationFiled: May 11, 2017Publication date: September 19, 2019Applicants: Bayer Healthcare LLC, Formulated Solutions, LLCInventors: Stephen Baldwin, Scott Carpenter, Heidi Graham, Nanhye Kim, Tom Meyer, David Reynolds, Jerry Vancleave, Eric Dann, Thomas Dann, Renee Nelson, Brian Dann
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Publication number: 20190282464Abstract: The present disclosure relates to, inter alia, a formulation in a package, the formulation comprises one or more active agents and is co-mingled with a whipping agent prior to being filled under pressure into the package. The whipping agent is added in sufficient amounts to be dispersed in the formulation. The pressurized package is under sufficient pressure suitable to maintain the whipping agent dispersed in the formulation; and the pressurized package is under sufficient pressure to expel the formulation as a whipped formulation upon application of external force on the formulation in the package.Type: ApplicationFiled: May 11, 2017Publication date: September 19, 2019Applicants: Bayer Healthcare LLC, Formulated Solutions, LLCInventors: Stephen Baldwin, Scott Carpenter, Heidi Graham, Nanhye Kim, Tom Meyer, David Reynolds, Jerry Vancleave, Eric Dann, Thomas Dann, Renee Nelson, Brian Dann
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Patent number: D863745Type: GrantFiled: June 14, 2018Date of Patent: October 22, 2019Assignee: BAYER HEALTHCARE LLCInventors: Alexander Fromholtz, Andrew Anthony Markle
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Patent number: D863746Type: GrantFiled: June 14, 2018Date of Patent: October 22, 2019Assignee: BAYER HEALTHCARE LLCInventors: Alexander Fromholtz, Andrew Anthony Markle
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Patent number: D864541Type: GrantFiled: June 14, 2018Date of Patent: October 29, 2019Assignee: BAYER HEALTHCARE LLCInventors: Alexander Fromholtz, Daniel L. Miranda, Andrew Anthony Markle
