Abstract: The present invention relates to substituted imidazopyridazine compounds of general formula (I): in which A, Q, R1, R3, R4 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
Type:
Grant
Filed:
September 20, 2012
Date of Patent:
April 26, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Knut Eis, Florian Puehler, Ludwig Zorn, Arne Scholz, Philip Lienau, Mark Jean Gnoth, Ulf Bömer, Judith Günther
Abstract: The present invention relates to N-cycloalkyl-N-biphenylmethyl-carboxamide derivatives of formula (I) wherein A, Z1, Z2, Z3, X, n, Y and m represent various substituents, their process of preparation, preparation intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.
Type:
Grant
Filed:
February 19, 2014
Date of Patent:
April 26, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Philippe Desbordes, Ralf Dunkel, Stephanie Gary, Marie-Claire Grosjean-Cournoyer, Benoit Hartmann, Philippe Rinolfi, Jean-Pierre Vors, Rachel Rama
Abstract: The present invention relates to N-Hetarylmethyl pyrazolylcarboxamides derivatives or their thiocarboxamides derivatives, their process of preparation, their use as fungicide, particularly in the form of compositions. Formula (I), and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.
Type:
Grant
Filed:
November 2, 2011
Date of Patent:
April 26, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Jurgen Benting, Pierre Cristau, Peter Dahmen, Philippe Desbordes, Stephanie Gary, Jan-Peter Schmidt, Ulrike Wachendorff-Neumann
Abstract: The present invention relates to novel phenyl(oxy/thio)alkanol derivatives, to processes for preparing these compounds, to compositions comprising these compounds and to their use as biologically active compounds, in particular for controlling harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
Type:
Grant
Filed:
August 13, 2014
Date of Patent:
April 26, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Carl Friedrich Nising, Klaus Kunz, Jörg Nico Greul, Hendrick Helmke, Gorka Peris, Jürgen Benting, Peter Dahmen, Isolde Hauser-Hahn, Ines Heinemann, Christian Paulitz, Dirk Schmutzler, Ulrike Wachendorff-Neumann, Tomoki Tsuchiya, Christoph Andreas Braun, Ruth Meissner, Thomas Knobloch
Abstract: The invention relates to a method for constructing bodies which, while rotating codirectionally about axes arranged in parallel, constantly touch one another at at least one point.
Abstract: The invention relates to novel tyrosine based linkers that allow the releasable connection of peptides or proteins with other molecular entities, e.g. polyethylene glycol, to processes for their preparation and their use for preparing medicaments for the treatment and/or prophylaxis of diseases.
Abstract: Heterocyclylpyri(mi)dinylpyrazole of the formula (I), in which R1 to R5, X1, U, Q, W, a, b and n have the meanings given in the description, and agrochemically active salts, to their use and to methods and compositions for controlling phytopathogenic harmful fungi in and/or on plants or in and/or on seed of plants and for reducing mycotoxins in plants and parts of the plants, to processes for preparing such compounds and compositions and treated seed and also to their use for controlling phytopathogenic harmful fungi in agriculture, horticulture, forestry, in animal husbandry, in the protection of materials, in the domestic and hygiene field and for the reduction of mycotoxins in plants and parts of the plants.
Type:
Grant
Filed:
October 4, 2012
Date of Patent:
April 19, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Alexander Sudau, Hendrik Helmke, Stefan Hillebrand, Amos Mattes, Lars Rodefeld, Pierre Wasnaire, Jürgen Benting, Peter Dahmen, Ulrike Wachendorff-Neumann, Philippe Desbordes, Anne-Sophie Rebstock
Abstract: Thiazolopyridinones of the general formula (I) are described as herbicides. In this formula (I), R1, R2, R3 and R4 represent radicals such as hydrogen, organic radicals such as alkyl and other radicals such as halogen, nitro and cyano.
Type:
Grant
Filed:
March 25, 2013
Date of Patent:
April 12, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Christian Waldraff, Stefan Lehr, Alfred Angermann, Hansjoerg Dietrich, Jan Dittgen, Elmar Gatzweiler, Christopher Hugh Rosinger, Angela Becker
Abstract: The present invention relates to a process for the activation of double metal cyanide (DMC) catalysts with heterocumulenes for the preparation of polyether carbonate polyols by catalytic copolymerization of carbon dioxide (CO2) with alkylene oxides in the presence of one or more H-functional starter substances, and to a process for the preparation of polyether carbonate polyols from one or more H-functional starter substances, one or more alkylene oxides and carbon dioxide in the presence of a double metal cyanide catalyst, characterized in that (?) under an inert gas atmosphere, under an atmosphere of an inert gas/carbon dioxide mixture or under a pure carbon dioxide atmosphere, at temperatures of from 90 to 150° C., the DMC catalyst is mixed with a heterocumulene and H-functional starter substance, (?) alkylene oxide is added at temperatures of from 100 to 150° C.
Type:
Grant
Filed:
July 16, 2012
Date of Patent:
April 12, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Thomas Ernst Müller, Christoph Gürtler, Yvonne Dienes, Julien Barruet, Burkhard Köhler, Walter Leitner
Abstract: The present application relates to novel substituted 6-fluoro-1H-pyrazolo[4,3-b]pyridines, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases and to the use thereof for preparing Medicaments for the treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
Type:
Grant
Filed:
November 3, 2011
Date of Patent:
April 12, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Jens Ackerstaff, Nils Griebenow, Andreas Knorr, Frank Wunder, Volkhart Min-Jian Li, Joachim Mittendorf, Karl-Heinz Schlemmer, Rolf Jautelat
Abstract: To provide pesticidal allylAryl heterocycle derivatives that are useful as a pesticidal compound. Pesticidal allylAryl heterocycle derivatives that are expressed by the Formula (I), and pesticides and an agent for controlling animal parasites which include the allylAryl heterocycle derivatives as an effective component.
Abstract: The present invention relates to a pharmaceutical composition which comprises progestogens, preferably drospirenone, estrogens, preferably ethinylestradiol and 5-methyl-(6S)-tetrahydrofolate, can be employed as oral contraceptive and moreover prevents disorders caused by folate deficiency in the consumers, in particular cardiovascular disorders and, after conception of the embryo, congenital malformations caused by folate deficiency such as, for example, neural tube defects, ventricular valve defects, urogenital defects, and cleft lip, jaw and palate, without masking the symptoms of vitamin B12 deficiency, and at the same time even in the case of homozygous or heterozygous polymorphism of methylenetetrahydrofolate reductase facilitates unimpaired utilizability of the folate component 5-methyl-(6S)-tetrahydrofolate by the body and thus its biological activity for preventing the abovementioned congenital malformations caused by folate deficiency.
Abstract: The invention relates to active compound combinations, in particular a fungicidal and/or insecticidal composition, comprising Isotianil (3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide) and at least one further insecticide of the anthranilamide group and optionally one further insecticide of the neonicotinoids. Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi and/or microorganisms and/or pests of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed.
Type:
Grant
Filed:
October 9, 2014
Date of Patent:
April 5, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Lutz Assmann, Ulrike Wachendorff-Neumann, Peter Dahmen, Heike Hungenberg, Wolfgang Thielert
Abstract: The present invention relates to the use of known pyridyl carboxamide derivatives and novel pyridyl carboxamide derivatives as nematicides, compositions containing such compounds and methods for the control of nematodes.
Type:
Grant
Filed:
October 29, 2012
Date of Patent:
April 5, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Jörg Nico Greul, Darren Mansfield, Martin Füsslein, Heiko Rieck, Matthias Riedrich, Lars Rodefeld, Kristian Kather, Olga Malsam, Peter Lösel, Arnd Voerste, Hans-Georg Schwarz, Kerstin Ilg, Ulrich Görgens, Lionel Carles, Pierre-Yves Coqueron, Philippe Desbordes, Philippe Meresse
Abstract: For selective treatment of diseased tissue sections or organ parts, the surface of medical devices entering into contact with areas thereof under pressure is coated with lipophilic substantially water-insoluble medicaments binding to various tissue components with good adherence thereto, said medicaments having an effect thereupon a short time after entering into contact therewith without exerting a harmful influence upon adjacent healthy tissue.
Abstract: The present invention relates to the use of new and known dithiine derivatives for controlling unwanted microorganisms, more particularly phytopathogenic fungi, in crop protection, in the household and hygiene sector and in the protection of materials, and also to new dithiine derivatives, to processes for preparing them, to their use, and to crop protection compositions comprising these new dithiine derivatives.
Type:
Grant
Filed:
March 11, 2013
Date of Patent:
March 29, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Thomas Seitz, Jurgen Benting, Ulrike Wachendorff-Neumann
Abstract: The present invention relates to a method for producing polyetherester carbonate polyols by means of catalytic addition of carbon dioxide, alkylene oxides and cyclic anhydrides to H-functional starter compounds in the presence of double metal cyanide (DMC) catalysts.
Type:
Grant
Filed:
December 10, 2012
Date of Patent:
March 29, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Christoph Guertler, Thoams Ernst Mueller, Anthony Kermagoret, Yvonne Dienes, Julien Barruet, Aurel Wolf, Stefan Grasser
Abstract: The present invention relates to the use of new and known dithiine derivatives for controlling unwanted microorganisms, more particularly phytopathogenic fungi, in crop protection, in the household and hygiene sector and in the protection of materials, and also to new dithiine derivatives, to processes for preparing them, to their use, and to crop protection compositions comprising these new dithiine derivatives.
Type:
Grant
Filed:
November 18, 2013
Date of Patent:
March 29, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Thomas Seitz, Jurgen Benting, Ulrike Wachendorff-Neumann
Abstract: The present invention relates to flame-resistant, thermoplastic molding compositions containing at least one aromatic polycarbonate, at least one flameproofing agent, at least one rubber-free anhydride-modified alpha-olefin terpolymer, at least one glass fiber, at least one antidripping agent, and optionally, at least one mold release agent and/or further additives. The present invention furthermore relates to the use of the compositions according to the invention for the production of thin-walled housing parts or switch boxes in the EE sector.
Type:
Grant
Filed:
November 30, 2012
Date of Patent:
March 29, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Michael Erkelenz, Hans Franssen, Helmut Werner Heuer
Abstract: The application relates to polymeric antistatic agents for use in polymer molding compositions, as well as molding compositions containing these antistatic agents, the antistatic agents having good compounding properties and being inexpensive to produce, wherein the antistatic agent is an antistatic agent of the general formula (I) having a polymeric cationic polyelectrolyte constituent produced from diallyldialkylammonium compounds and an anionic counterion A?, in which R1 is uniformly or mutually independently C1-C18 alkyl, A? is an acid anion, and n is a whole number from 10 to 1000.