Abstract: Polymer compositions with improved lacquer adhesion comprising A) 30 to 80 parts by wt. of at least one polymer chosen from the group of aromatic polycarbonates and aromatic polyester carbonates, B) 2 to 40 parts by wt. of at least one rubber-free and/or rubber-modified vinyl (co)polymer, the rubber-modified vinyl (co)polymers being prepared in the bulk, solution or suspension polymerization process, C) 0.5 to 20.0 parts by wt. of at least one rubber-modified vinyl (co)polymer prepared in the emulsion polymerization process, D) 2 to 16 parts by wt. of at least one polymer, E) 0 to 35 parts by wt. of at least one inorganic filler or reinforcing substance, F) 0.01 to 20.0 parts by wt. of at least one polymer additive, wherein the sum of the parts by weight of components A+B+C+D+E+F in the composition is 100.
Abstract: The present invention relates to heterocyclyl aminoimidazopyridazine compounds of general formula (I): in which A, R1, R2, R3 and R4 are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
Type:
Grant
Filed:
June 21, 2012
Date of Patent:
March 15, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Knut Eis, Florian Pühler, Ludwig Zorn, Arne Scholz, Philip Lienau, Mark Jean Gnoth, Ulf Bömer, Judith Günther, Jörg Fanghänel, Daniel Korr
Abstract: A process for the preparation of a solid, orally administrable pharmaceutical composition, comprising 5-chloro-N-({(5)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide comprising preparing granules in hydrophilized form using fluidized bed granulation for moist granulation, adding additives, compressing to form a tablet, and coating the tablet.
Abstract: The present invention relates to substituted imidazopyrazine compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined in the claims, to methods of and intermediates for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
Type:
Grant
Filed:
December 13, 2011
Date of Patent:
March 15, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Marcus Koppitz, Ulrich Klar, Rolf Jautelat, Dirk Kosemund, Rolf Bohlmann, Benjamin Bader, Philip Lienau, Gerhard Siemeister
Abstract: The present invention relates to a process for the preparation of a solid, orally administrable pharmaceutical composition, comprising 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide in hydrophilized form, and its use for the prophylaxis and/or treatment of diseases.
Abstract: The invention relates to substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-ones, in particular for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of neoplastic disorders.
Type:
Grant
Filed:
July 31, 2012
Date of Patent:
March 8, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Ningshu Liu, Kai Thede, Ursula Mönning, Arne Scholz, Christoph-Stephan Hilger, Ulf Bömer, Reiner Fischer
Abstract: The invention relates to a method for producing light-coloured polyisocyanates by phosgenation of mixtures comprising MDA and polycyclic aromatic polyamines that have o-phenylenediamine units incorporated via methylene bridges. The invention further relates to the polyisocyanate mixtures obtainable by this method.
Type:
Grant
Filed:
October 18, 2012
Date of Patent:
March 8, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Thomas Ernst Mueller, Christoph Guertler, Axel Scherer-Werke, Stefan Wershofen, Henning Vogt, Walter Leitner
Abstract: The present invention relates to a novel process for the preparation of 1-H-pyrrolidine-2,4-dione derivatives and to novel intermediates and to a process for their preparation.
Abstract: Processes for electrolysis of alkali metal chlorides with oxygen-consuming electrodes having startup and shutdown conditions which prevent damage to the constituents of the electrolysis cell.
Type:
Grant
Filed:
February 21, 2013
Date of Patent:
March 1, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Andreas Bulan, Rainer Weber, Jürgen Kintrup
Abstract: The invention is directed to arylpyrrolidines compounds which exhibit excellent insecticidal efficacy and which may be used as in the agrochemical field or in the field of veterinary medicine. The compounds are represented by formula (I): wherein the respective substituents are defined in the specification.
Abstract: The present application relates to novel bisaryl-linked 5-aryl-1,2,4-triazolone derivatives, to processes for preparing them, to their use alone or in combinations for the treatment and/or prevention of diseases and also to their use for the production of medicaments for the treatment and/or prevention of diseases, more particularly for the treatment and/or prevention of cardiovascular disorders.
Type:
Application
Filed:
November 2, 2015
Publication date:
February 25, 2016
Applicant:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Chantal FÜRSTNER, Jörg KELDENICH, Martina DELBECK, Peter KOLKHOF, Axel KRETSCHMER, Ingo PLUSCHKELL, Elisabeth POOK, Carsten SCHMECK, Hubert TRÜBEL
Abstract: The invention is directed to arylpyrrolidines compounds which exhibit excellent insecticidal efficacy and which may be used as in the agrochemical field or in the field of veterinary medicine. The compounds are represented by formula (I): wherein the respective substituents are defined in the specification.
Abstract: The present invention relates to a catalyst comprising a ceramic support with a BET surface area of less than 40 m2/g and (a) 1.0 to 100 g of at least one metal of groups 8 to 12 of the periodic table of the elements, (b) 1.0 g to 100 g of at least one metal of groups 4 to 6 and 12 of the periodic table of the elements and (c) 1.0 g to 100 g of at least one metal of groups 14 and 15 of the periodic table of the elements per liter of bulk volume of the ceramic support, wherein the catalyst is additionally doped with (d) potassium in a content of from 0.0050% by weight to 0.20% by weight, based on the total weight of the catalyst. The present invention also provides the use of such a catalyst in the catalytic gas phase hydrogenation of nitroaromatics.
Type:
Grant
Filed:
August 29, 2012
Date of Patent:
February 23, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Michael Merkel, Karl-Heinz Wilke, Peter Lehner
Abstract: Compounds of formula (I) which are inhibitors of Bub1 kinase, processes for their production and their use as pharmaceuticals.
Type:
Grant
Filed:
October 4, 2012
Date of Patent:
February 23, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Marion Hitchcock, Anne Mengel, Vera Pütter, Gerhard Siemeister, Antje Margret Wengner, Hans Briem, Knut Eis, Volker Schulze, Amaury Ernesto Fernandez-Montalvan, Stefan Prechtl, Simon Holton, Jörg Fanghänel, Philip Lienau, Cornelia Preusse, Mark Jean Gnoth
Abstract: The present invention relates to novel active compound combinations which include of the insecticidally active compounds of the formula (I) in combination with fungicidally active compounds (II) and are highly suitable for controlling unwanted animal pests, such as insects, and unwanted phytopathogenic fungi.
Type:
Grant
Filed:
July 7, 2011
Date of Patent:
February 23, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Christian Funke, Heike Hungenberg, Rüdiger Fischer
Abstract: The invention provides combinations of insecticides/acaricides and herbicides comprising an effective amount of components (A) and (B), where component (A) is one or more of the tetramic acid derivatives listed in the description, and (B) one or more herbicides from the group of the herbicides likewise listed in the description, where the combinations may optionally additionally comprise crop plant compatibility-increasing substances (safeners). The invention also relates to the use of the combinations for controlling animal pests and unwanted vegetation and to the corresponding methods.
Type:
Grant
Filed:
August 7, 2012
Date of Patent:
February 23, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Michael Deall, Reiner Fischer, Erwin Hacker, Heike Hungenberg, John Bell, Robert Steffens
Abstract: The present invention relates to a process for the preparation of substituted N-(benzyl)cyclopropanamines of the general formula (II) starting from N-[(aryl)methylene]cyclopropanamine derivatives. The present invention further provides the N-[(aryl)methylene]cyclopropanamine derivatives used as starting compounds in this process according to the invention, and their use for the preparation of substituted N (benzyl)cyclopropanamines.
Type:
Grant
Filed:
November 4, 2011
Date of Patent:
February 16, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Norbert Lui, Wahed Ahmed Moradi, Thomas Norbert Muller
Abstract: Insecticidal compositions, characterized by an effective amount of a combination of active compounds comprising (a) at least one compound of the formula (I) in which Het, A, R and X are as defined in the description, and (b) at least one crop plant compatibility-improving compound from the group of compounds listed in the description, which are used for controlling arthropods, and also methods for controlling arthropods by treating plants and their seed with the compositions.
Inventors:
Marion Hitchcock, Anne Mengel, Anja Richter, Hans Briem, Knut Eis, Vera Pütter, Gerhard Siemeister, Stefan Prechtl, Amaury Ernesto Fernández-Montalván, Christian Stegmann, Simon Holton, Mark Jean Gnoth, Cornelia Preuβe
Abstract: The invention relates to a process for the preparation of polycarbonate polyols, characterized in that cyclic carbonates are polymerized in the presence of DMC catalysts and chain-transfer agents consisting of polyether carbonate polyols.
Type:
Grant
Filed:
November 3, 2011
Date of Patent:
February 16, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Thomas Ernst Müller, Christoph Gürtler, Anthony Kermagoret, Yvonne Dienes, Igor Busygin, Burkhard Köhler, Walter Leitner, Ganna Lyashenko