Abstract: 5-phenyl-substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamides of the general formula (I) are described as herbicides. In this formula (I), W, X, Y, Z and R are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen. A and B are N and CY.
Type:
Grant
Filed:
October 29, 2012
Date of Patent:
February 16, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Ralf Braun, Hartmut Ahrens, Andreas Van Almsick, Stefan Lehr, Isolde Häuser-Hahn, Hansjörg Dietrich, Elmar Gatzweiler, Ines Heinemann, Christopher Hugh Rosinger
Abstract: The invention relates to a method of improving grass quality comprising applying an effective amount of a composition containing a phthalocyanine to the grass in the substantial absence of phosphorous acid, monoalkyl esters of phosphorous acid, or salts thereof.
Type:
Grant
Filed:
October 24, 2014
Date of Patent:
February 16, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Lawrence H. Norton, Richard Hanrahan, David R. Spak
Abstract: The invention provides herbicide combinations and the use of herbicide combinations for controlling harmful plants in cereal crops wherein the herbicide combination in question comprises (A) a herbicide from the group of glufosinate derivatives of the formula (A1) in which Z represents hydroxyl, —NHCH(CH3)CONHCH(CH3)COOH or —NHCH(CH3)CONHCH[CH2CH(CH3)2]COOH, or an ester or salt thereof, and (B) a herbicide from the group of carboxylic acid derivatives of the formula (B1) in which X represents N or CH and R represents CO2H or a herbicidally active derivative thereof, and the cereal crops are tolerant, if appropriate in the presence of safeners, to the herbicides (A) and (B) present in the combination.
Type:
Grant
Filed:
May 19, 2011
Date of Patent:
February 9, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Erwin Hacker, Hansjörg Dietrich, Hubert Menne, Elmar Gatzweiler, Frank Ziemer
Abstract: The present invention relates to substituted imidazopyridazine compounds of general formula (I), which are Mps-1 (Monopolar Spindle 1) Kinase inhibitors (also known as Tyrosine Threonine Kinase, TTK) in which R3, R5, and A are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
Type:
Grant
Filed:
September 6, 2011
Date of Patent:
February 9, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Ulrich Klar, Marcus Koppitz, Rolf Jautelat, Dirk Kosemund, Rolf Bohlmann, Philip Lienau, Gerhard Siemeister, Antje Margret Wengner
Abstract: The novel active compound combinations comprising 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione of the formula and the active compound of groups (1) to (24) listed in the description have very good fungicidal properties.
Type:
Grant
Filed:
November 8, 2013
Date of Patent:
February 9, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Stefan Dutzmann, Klaus Stenzel, Manfred Jautelat
Abstract: The present invention relates to a process for the activation of double metal cyanide (DMC) catalysts and to a process for the preparation of polyethercarbonate polyols from one or more H-functional starter compounds, one or more alkylene oxides and carbon dioxide in the presence of a double metal cyanide catalyst, characterized in that (?) (?1) the DMC catalyst and one or more H-functional starter compounds are placed in a reactor, (?2) an inert gas, an inert gas/carbon dioxide mixture or carbon dioxide is passed through the reactor at a temperature of 50 to 200° C. and at the same time a reduced pressure (absolute) of 10 mbar to 800 mbar is established in the reactor by removal of the inert gas or carbon dioxide, (?) under an atmosphere of inert gas/carbon dioxide mixture or under a pure carbon dioxide atmosphere, alkylene oxide is added to the mixture from step (?) at temperatures of 50 to 200° C.
Type:
Grant
Filed:
July 17, 2012
Date of Patent:
February 2, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Thomas Ernst Müller, Christoph Gürtler, Matthias Wohak, Jörg Hofmann, Muhammad Afzal Subhani, Maurice Cosemans, Walter Leitner
Abstract: Bis(difluoromethyl)pyrazole derivatives of the formula (I) in which the symbols R1, X and G are each as defined in the description, and agrochemically active salts, metal complexes and N-oxides thereof, and use thereof for controlling phytopathogenic harmful fungi, and also processes for preparing compounds of the formula (I).
Type:
Grant
Filed:
September 12, 2014
Date of Patent:
February 2, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Pierre Cristau, Sebastian Hoffmann, Joachim Kluth, Tomoki Tsuchiya, Pierre Wasnaire, Jurgen Benting, Daniela Portz, Ulrike Wachendorff-Neumann, Stefan Hillebrand
Abstract: For safe storage and simple and safe administration of tablets T by a user, a cartridge 900 is provided that can be inserted into a medicament dispenser 1 for solid medicament portions T and that is designed with a reservoir for receiving the medicament portions T, and a medicament dispenser 1 containing this cartridge 900 is also provided. According to the invention, the cartridge 900 comprises a transport safety mechanism for preventing movement of the medicament portions T during storage and transport of the cartridge 900 . This transport safety mechanism is in particular a tolerance compensation plug 970 that sits with a frictional fit in the reservoir and that is movable in the axial direction.
Type:
Grant
Filed:
November 14, 2009
Date of Patent:
February 2, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Sabine Leifeld, Tom Reinhold, Sven Filler, Uwe Karla
Abstract: A combination comprising an enaminocarbonyl compound of formula (I): wherein R is methyl, cyclopropyl or 2,2-difluoroethyl, and at least one biological control agent selected from bacteria, fungi or yeasts, protozoas, viruses, and entomopathogenic nematodes, and optionally an inoculant, for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, mites nematodes and phytopathogens.
Abstract: The present invention is directed to the neutralizing prolactin receptor antibody 005-C04, as well as maturated forms thereof, and antigen binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation. The antibodies of the invention block prolactin receptor-mediated signaling.
Type:
Grant
Filed:
November 18, 2010
Date of Patent:
January 26, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Christiane Otto, Siegmund Wolf, Christoph Freiberg, Axel Harrenga, Simone Greven, Mark Trautwein, Sandra Bruder, Andrea Eicker, Andreas Wilmen
Abstract: The present invention relates to the use of active substance combinations which consist firstly of known cyclic ketoenols and secondly of further known insecticidal active substances, for controlling animal pests from the stink bug family (Pentatomidae).
Type:
Grant
Filed:
February 18, 2014
Date of Patent:
January 26, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Reiner Fischer, Konrad Kemper, Jürgen Kühnhold, Xavier Alain Marie Van Waetermeulen, Francisco Leonel Junior Lozano
Abstract: The present invention relates to novel substituted pyrimidine derivatives, to processes for preparing these compounds, to compositions comprising these compounds and to their use as biologically active compounds, in particular for controlling harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
Type:
Grant
Filed:
November 28, 2011
Date of Patent:
January 26, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Carl Friedrich Nising, Graham Holmwood, Hendrik Helmke, Gorka Peris, Tomoki Tsuchiya, Alexander Sudau, Jürgen Benting, Peter Dahmen, Ulrike Wachendorff-Neumann
Abstract: The present invention relates to disubstituted pyridine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, immunological diseases, autoimmune diseases, cardiovascular diseases, cell proliferative diseases, inflammation, erectile dysfunction and stroke, and pharmaceutical compositions containing at least one of said disubstituted pyridine derivatives and/or pharmaceutically acceptable salts thereof. Furthermore, the present invention relates to the use of said disubstituted pyridine derivatives as inhibitors for a protein kinase.
Type:
Grant
Filed:
March 1, 2012
Date of Patent:
January 26, 2016
Assignees:
Bayer Intellectual Property GmbH, LEAD DISCOVERY CENTER GMBH
Inventors:
Gerd Rühter, Peter Nussbaumer, Axel Choidas, Carsten Schulz-Fademrecht, Bert Klebl, Jan Eickhoff
Abstract: The present invention relates to a process for the preparation of a hydroxy-amino polymer, comprising the steps: a) reacting an H-functional starter compound carrying at least one Zerewitinoff-active H atom with an unsaturated cyclic carboxylic acid anhydride to give a carboxyl-group-carrying prepolymer, b) reacting the carboxyl-group-carrying prepolymer with at least one epoxide compound to give a hydroxyl-group-carrying prepolymer, c) adding a primary amine and/or ammonia to the double bond of the hydroxyl-group-carrying prepolymer obtained according to step b) to give the hydroxy-amino polymer, wherein the ratio of the amount of carboxylic acid anhydride to the number of Zerewitinoff-active H atoms of the H-functional starter compound is so chosen that almost all the Zerewitinoff-active H atoms of the H-functional starter compound are reacted.
Type:
Grant
Filed:
December 17, 2012
Date of Patent:
January 19, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Jorg Hofmann, Klaus Lorenz, Hartmut Nefzger
Abstract: The present invention relates to fungicidal N-[(het)arylethyl)] pyrazolecarboxamide or thiocarboxamide and their heterosubstituted analogues, their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.
Type:
Grant
Filed:
June 1, 2011
Date of Patent:
January 12, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Jurgen Benting, Christoph Braun, Pierre-Yves Coqueron, Pierre Cristau, Peter Dahmen, Philippe Desbordes, Stephanie Gary, Jorg Greul, Hiroyuki Hadano, Thomas Knobloch, Ruth Meissner, Ulrike Wachendorff-Neumann, Lothar Willms
Abstract: The invention relates to the use of succinate dehydrogenase inhibitors, especially of fluopyram, for controlling Sclerotinia ssp., to a method for treating plants or plant parts for controlling Sclerotinia ssp. and to a method for treating seed for controlling Sclerotinia ssp. in the seed and in the plants which grow from the seed, by treating the seed with a succinate dehydrogenase inhibitor.
Type:
Grant
Filed:
June 2, 2010
Date of Patent:
January 12, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Ingo Wetcholowsky, Heiko Rieck, Gilbert Labourdette, Jose Augusto Geraldes
Abstract: The present invention relates to novel heterocyclic compounds, to processes for preparation thereof and to the use thereof for controlling animal pests, which include arthropods and especially insects.
Type:
Grant
Filed:
July 15, 2011
Date of Patent:
January 12, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Friedrich August Mühlthau, Thomas Bretschneider, Reiner Fischer, Martin Füβlein, Markus Heil, Achim Hense, Joachim Kluth, Adeline Köhler, Eva-Maria Franken, Olga Malsam, Arnd Voerste, Peter Jeschke, Angela Becker, Peter Lösel, Yoshitaka Sato
Abstract: The invention relates to a process for purifying aniline produced by gas-phase hydrogenation of nitrobenzene, by fractional condensation of the crude reaction product obtained in gaseous form so that at least two liquid process products, a partial condensate (PK) and a total condensate (TK), are obtained.
Type:
Grant
Filed:
October 17, 2011
Date of Patent:
January 12, 2016
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Peter Lehner, Knut Sommer, Amgad Salah Moussa
Abstract: The invention relates to the use of one or more acylsulfonamide safener compounds of formula (I): for modifying plant development of useful plants. The use provides an increase in root growth and/or a regulation in shoot growth of the plants.
Type:
Grant
Filed:
December 9, 2008
Date of Patent:
January 12, 2016
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Christopher Hugh Rosinger, Frank Ziemer
Abstract: The object of the present invention is to provide novel carboxamides which exhibit an excellent pesticidal activity as pesticides. Disclosed are the carboxamides represented by the following Formula (I): wherein each substituent is as defined in the specification, and use thereof as pesticides and animal parasite controlling agents.