Patents Assigned to Bayer Intellectual Property GmbH
  • Patent number: 9636344
    Abstract: The present invention relates to 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo-[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide dihydrochloride salt of formula (II): or a tautomer, solvate or hydrate thereof; and to its use for the treatment of non-Hodgkin's lymphoma.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: May 2, 2017
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Jan-Georg Peters, Hans-Christian Militzer, Hartwig Müller
  • Patent number: 9629367
    Abstract: The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a thiazolylisoxazoline of formula (I) and a further fungicidally active compound (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: April 25, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Ulrike Wachendorff-Neumann, Sebastian Hoffmann, Pierre Wasnaire
  • Patent number: 9624309
    Abstract: This invention relates to monospecific and multispecific antibodies that may be utilized for the diagnosis and treatment of various diseases. In addition, these antibodies may be modified by protease cleavage. Protease control or regulation may be provided by a protease site located in, for example, a linker. These protease-regulated antibodies may also be utilized for the diagnosis and treatment of various diseases.
    Type: Grant
    Filed: August 16, 2008
    Date of Patent: April 18, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GmbH
    Inventors: Bing Liu, David Light, Zhuozhi Wang, Douglas Schneider
  • Patent number: 9617286
    Abstract: The present invention relates to fungicidal N-[(trisubstitutedsilyl)methyl]carboxamide or its thiocarboxamide derivatives with formula: their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: April 11, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Juergen Benting, Pierre Cristau, Philippe Desbordes, Helene Lachaise, Philippe Rinolfi
  • Patent number: 9610297
    Abstract: The invention relates to preparations comprising vitamin B12 and a butanol, and to the use of butanol for stabilizing vitamins.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: April 4, 2017
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Iris Heep, Hans-Rolf Taterra
  • Patent number: 9609871
    Abstract: The invention relates to novel compositions for controlling parasites on animals, comprising an N-arylpyrazole and also a pyrethroid in a formulation comprising aliphatic cyclic carbonates and aliphatic cyclic or acyclic polyethers.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: April 4, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Kirkor Sirinyan, Andreas Turberg
  • Patent number: 9609863
    Abstract: Herbicide-safener compositions are described, comprising active herbicidal ingredients from the group of the N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamides and safeners. These herbicide-safener compositions are particularly suitable for use against harmful plants in crops of useful plants.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: April 4, 2017
    Assignee: Bayer Intellectual Property GMBH
    Inventors: Ralf Braun, Hartmut Ahrens, Andreas Van Almsick, Simon Dörner-Rieping, Arnim Köhn, Christopher Rosinger, Elmar Gatzweiler, Erwin Hacker
  • Patent number: 9603936
    Abstract: The invention relates to novel polyethylene glycol (PEG) based prodrug of Adrenomedullin, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for producing medicaments for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders.
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: March 28, 2017
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Ingo Flamme, Johannes Köbberling, Hans-Georg Lerchen, Nils Griebenow, Rudolf Schohe-Loop, Sven Wittrock, Maria Köllnberger, Frank Wunder, Gorden Redlich, Andreas Knorr, Julie Marley, Iain Pritchard
  • Patent number: 9604989
    Abstract: The present invention relates to a method for the treatment of a cancer that is sensitive to Pi3K/Akt pathway inhibition by administering a therapeutically effective amount of a compound of formula (I)
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: March 28, 2017
    Assignees: BAYER INTELLECTUAL PROPERTY GMBH, BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Lars Bärfacker, William Scott, Andrea Hägebarth, Stuart Ince, Hartmut Rehwinkel, Oliver Politz, Roland Neuhaus, Hans Briem, Ulf Bömer
  • Patent number: 9596862
    Abstract: Compositions are provided that improve overall plant vigor and yield by combining agriculturally effective amounts of at least one environmentally friendly biological control agent and at least one insect control agent and or fungicide. A composition of the present invention is particularly effective in the presence of plant parasitic nematode and fungal species. Along with a benefit of reducing insect pressure, the inventive composition enhances the root system of a plant and improves the establishment of the biological control agent within the rhizosphere, thereby enhancing the effectiveness thereof. Use of a composition of the present invention leads to an overall reduction in crop losses caused by either plant parasitic nematodes or fungi and this reduction is much greater than would have bean expected from application of either component alone. Methods for utilizing compositions of the present invention are also provided.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: March 21, 2017
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Wolfram Andersch, Paul Hawen Evans, Bernd Springer, Kevin Bugg, Jennifer Riggs, Chi-Yu Roy Chen
  • Patent number: 9598416
    Abstract: This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-fJ[1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases.
    Type: Grant
    Filed: December 11, 2012
    Date of Patent: March 21, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Marie-Pierre Collin, Dirk Brohm, Mélanie Héroult, Mario Lobell, Walter Hübsch, Klemens Lustig, Sylvia Grünewald, Ulf Bömer, Verena Vöhringer, Niels Lindner
  • Patent number: 9592245
    Abstract: The present invention relates to a very low-dosed dosage form for hormone replacement therapy (HRT). More particularly, the present invention concerns a solid oral dosage form comprising about 0.5 mg estradiol and about 0.25 mg drospirenone, and at least one pharmaceutically acceptable excipient. Despite the very low E2 and DRSP doses it has surprisingly been found that a high proportion of the women suffering from moderate to severe hot flushes actually respond to this treatment. Accordingly, the dosage form of the invention may be used as maintenance HRT or may be used already when HRT is initiated.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: March 14, 2017
    Assignee: Bayer Intellectual Property GMBH
    Inventors: Stephan Mletzko, Rolf Schürmann, Kerstin Gude
  • Patent number: 9591856
    Abstract: The present invention relates to novel fungicide compositions comprising (A) fluopyram, (B) at least one further succinate dehydrogenase (SDH) inhibitor and optionally further (C) at least one triazole fungicide, whereas the invention especially comprises such novel fungicide compositions of (A) fluopyram, (B) bixafen and (C) at least one triazole fungicide, which is preferably prothioconazole. The present invention also relates to the use of such novel fungicide compositions for improving growth in crops, comprising preventively and/or curatively controlling pathogenic fungi and/or nematodes, resistance management, and improving plant physiology effects by enhancing root growth, improving greening, improving water use efficiency, improving nitrogen-use efficacy, delaying senescence and enhancing yield.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: March 14, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Ulrich Krieg, Damien Viollet, Andreas Görtz
  • Patent number: 9593140
    Abstract: The present invention relates to new macrolide derivatives, in particular new tylosin derivatives of the formula (I); a pharmaceutical or veterinary composition comprising the derivatives; a method for preparation thereof; a method for treating and/or preventing bacterial infections in an animal, wherein the method comprises administering the derivatives or the composition; and a use of the derivatives for the manufacture of medicaments for treating and/or preventing bacterial infections in an animal.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: March 14, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Gerd Kleefeld, Robrecht Froyman, Julia Charlotte Dörner, Carolin Ludwig, Omura Satoshi, Sunazuka Toshiaki, Hirose Tomoyasu, Sugawara Akihiro, Shiomi Kazuro
  • Publication number: 20170057918
    Abstract: The present invention relates to a process for preparing 4-{4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy}-N-methylpyridine-2-carboxamide, its salts and monohydrate.
    Type: Application
    Filed: September 8, 2016
    Publication date: March 2, 2017
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Juergen STIEHL, Werner HEILMANN, Michael LÖGERS, Joachim REHSE, Michael GOTTFRIED, Saskia WICHMANN
  • Patent number: 9572342
    Abstract: A composition comprising a compound of formula (I): in which R1, R2, R3, R4, R5, R6, A, Q and n can have the definitions stated in the description, and at least one biological control agent selected from bacteria, fungi or yeasts, protozoas, viruses, entomopathogenic nematodes, and botanical extracts, or products produced by microorganisms including proteins or secondary metabolites, and optionally an inoculant, for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, nematodes and phytopathogens.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: February 21, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Rüdiger Fischer, Heiki Hungenberg
  • Patent number: 9572315
    Abstract: The present invention relates to an ALS inhibitor herbicide tolerant B. napus plant, progeny and parts thereof comprising a non-transgenic mutation of an endogenous acetolactate synthase I gene and a non-transgenic mutation of an endogenous acetolactate synthase III gene.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: February 21, 2017
    Assignees: BAYER INTELLECTUAL PROPERTY GMBH, DEUTSCHE SAATVEREDELUNG AG
    Inventors: Rüdiger Hain, Günter Donn, Nathalie Knittel-Ottleben, Heinrich Busch, Carsten Oertel, Dieter Stelling
  • Patent number: 9562249
    Abstract: The present invention is directed to an innate DNA sequence within the complete genome sequence of Actinoplanes sp. SE50/110 which resembles the structure of an actinomycete integrative and conjugative element (AICE). Related AICEs were used for establishing genetic manipulation tools for other bacteria in the past. In this document, we describe the unique features of the specific AICE found in Actinoplanes sp. SE50/110 which are clearly distinct from any other known AICE as a whole, but share minor parts with varying sequence similarity with other characterized AICEs from other species.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: February 7, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Andreas Klein, Klaus Selber, Hermann Wehlmann, Winfried Rosen, Alfred Pühler, Patrick Schwientek, Jörn Kalinowski, Udo Wehmeier
  • Patent number: 9560852
    Abstract: Compositions are provided that improve overall plant vigor and yield by combining agriculturally effective amounts of at least one environmentally friendly biological control agent and at least one insect control agent and or fungicide. A composition of the present invention is particularly effective in the presence of plant parasitic nematode and fungal species. Along with a benefit of reducing insect pressure, the inventive composition enhances the root system of a plant and improves the establishment of the biological control agent within the rhizosphere, thereby enhancing the effectiveness thereof. Use of a composition of the present invention leads to an overall reduction in crop losses caused by either plant parasitic nematodes or fungi and this reduction is much greater than would have been expected from application of either component alone. Methods for utilizing compositions of the present invention are also provided.
    Type: Grant
    Filed: April 7, 2009
    Date of Patent: February 7, 2017
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Wolfram Andersch, Paul Hawen Evans, Bernd Springer, Kevin Bugg, Jennifer Riggs, Chi-Yu Roy Chen
  • Patent number: 9555022
    Abstract: The present invention relates to substituted triazolopyridine compounds of general formula (I): in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease of uncontrolled cell growth, proliferation and/or survival as well as to the use of intermediate compounds for the preparation of said compounds.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: January 31, 2017
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Volker Schulze, Dirk Kosemund, Hartmut Schirok, Benjamin Bader, Philip Lienau, Antje Margret Wengner, Hans Briem, Simon Holton, Gerhard Siemeister, Stefan Prechtl, Marcus Koppitz, Detlef Stöckigt, Olaf Prien