Patents Assigned to Bayer
  • Deployment actuation system
    Patent number: 9597224
    Abstract: Contraceptive methods, systems, and devices generally improve the ease, speed, and reliability with which a contraceptive device can be deployed transcervically into an ostium of a fallopian tube. The contraceptive device may remain in a small profile configuration while a sheath is withdrawn proximally, and is thereafter expanded to a large profile configuration engaging the surrounding tissues, by manipulating one or more actuators of a proximal handle with a single hand. This leaves the other hand free to manipulate a hysteroscope, minimizing the number of health care professional required to deploy the contraceptive device.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: March 21, 2017
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Christian Lowe, Donnell Gurskis, Ashish Khera, Monica Sharmane Barnhart Nachbar, Steven Bacich, Betsy Swann, Roberto Silva-Torres
  • HETEROCYCLIC COMPOUNDS AS PESTICIDES
    Publication number: 20170073318
    Abstract: The present application relates to novel heterocyclic compounds, to the use thereof for controlling animal pests including arthropods, insects and nematodes, and to processes and intermediates for preparation of the novel compounds.
    Type: Application
    Filed: March 4, 2015
    Publication date: March 16, 2017
    Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Eike Kevin HEILMANN, Heinz-Juergen WROBLOWSKY, Axel TRAUTWEIN, Joerg GREUL, Hardwin DEMBSKI, Kerstin ILG, Daniela PORTZ, Ulrich GOERGENS
  • Monoclonal antibodies against antithrombin ?
    Patent number: 9593166
    Abstract: This patent document relates to antibodies, antigen-binding antibody fragments (Fabs), and other protein scaffolds, directed against human antithrombin ? complexed with heparin and/or heparin-like structure (AT?H). These AT?H binding proteins can block the anti-coagulant activity of AT? to induce coagulation. Therapeutic uses of these antibodies and binders are described herein as are methods of panning and screening specific antibodies.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 14, 2017
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Ye Jin, John E. Murphy, Terry Hermiston, Timothy Myles, Frank Dittmer, Michael Strerath, Uwe Gritzan
  • Very low-dosed solid oral dosage forms for HRT
    Patent number: 9592245
    Abstract: The present invention relates to a very low-dosed dosage form for hormone replacement therapy (HRT). More particularly, the present invention concerns a solid oral dosage form comprising about 0.5 mg estradiol and about 0.25 mg drospirenone, and at least one pharmaceutically acceptable excipient. Despite the very low E2 and DRSP doses it has surprisingly been found that a high proportion of the women suffering from moderate to severe hot flushes actually respond to this treatment. Accordingly, the dosage form of the invention may be used as maintenance HRT or may be used already when HRT is initiated.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: March 14, 2017
    Assignee: Bayer Intellectual Property GMBH
    Inventors: Stephan Mletzko, Rolf Schürmann, Kerstin Gude
  • Methods and means to modify a plant genome at a nucleotide sequence commonly used in plant genome engineering
    Patent number: 9593317
    Abstract: Methods and means are provided to modify in a targeted manner the plant genome of transgenic plants comprising chimeric genes wherein the chimeric genes have a DNA element commonly used in plant molecular biology. Re-designed meganucleases to cleave such an element commonly used in plant molecular biology are provided.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: March 14, 2017
    Assignee: Bayer CropScience NV
    Inventor: Kathleen D'Halluin
  • Fungicide compositions comprising fluopyram, at least one succinate dehydrogenase (SDH) inhibitor and optionally at least one triazole fungicide
    Patent number: 9591856
    Abstract: The present invention relates to novel fungicide compositions comprising (A) fluopyram, (B) at least one further succinate dehydrogenase (SDH) inhibitor and optionally further (C) at least one triazole fungicide, whereas the invention especially comprises such novel fungicide compositions of (A) fluopyram, (B) bixafen and (C) at least one triazole fungicide, which is preferably prothioconazole. The present invention also relates to the use of such novel fungicide compositions for improving growth in crops, comprising preventively and/or curatively controlling pathogenic fungi and/or nematodes, resistance management, and improving plant physiology effects by enhancing root growth, improving greening, improving water use efficiency, improving nitrogen-use efficacy, delaying senescence and enhancing yield.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: March 14, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Ulrich Krieg, Damien Viollet, Andreas Görtz
  • Antibacterial tylosin derivatives and methods for their preparation
    Patent number: 9593140
    Abstract: The present invention relates to new macrolide derivatives, in particular new tylosin derivatives of the formula (I); a pharmaceutical or veterinary composition comprising the derivatives; a method for preparation thereof; a method for treating and/or preventing bacterial infections in an animal, wherein the method comprises administering the derivatives or the composition; and a use of the derivatives for the manufacture of medicaments for treating and/or preventing bacterial infections in an animal.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: March 14, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Gerd Kleefeld, Robrecht Froyman, Julia Charlotte Dörner, Carolin Ludwig, Omura Satoshi, Sunazuka Toshiaki, Hirose Tomoyasu, Sugawara Akihiro, Shiomi Kazuro
  • Antibody and protein formulations
    Patent number: 9592297
    Abstract: Provided are salt-free antibody and other protein formulations that are substantially isosmotic and of low viscosity. Also provided are methods for the treatment of diseases using the disclosed formulations.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 14, 2017
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Jun Xiang, Xinghang Ma
  • Prodrug derivatives of substituted triazolopyridines
    Patent number: 9586958
    Abstract: The present invention relates to prodrug derivatives of Mps-1 kinase inhibitors, processes for their preparation, and their use for the treatment and/or prophylaxis of diseases.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: March 7, 2017
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Volker Schulze, Hans-Georg Lerchen, Donald Bierer, Antje Margret Wengner, Gerhard Siemeister, Philip Lienau, Ursula Krenz, Dirk Kosemund, Detlef Stöckigt, Michael Brüning, Ulrich Lücking, Ildikó Terebesi
  • Compositions comprising a biological control agent and an insecticide
    Patent number: 9585399
    Abstract: The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: March 7, 2017
    Assignee: Bayer CropScience AG
    Inventors: Elke Hellwege, Wolfram Andersch, Klaus Stenzel, Bernd Springer
  • 3-phenylisoxazolin derivatives with herbicidal action
    Patent number: 9585392
    Abstract: 3-Phenylisoxazoline derivatives of the formula (I), and the use thereof as herbicides, are described. In this formula (I), X2 to X6 and R1 to R3 are radicals such as hydrogen, halogen, and organic radicals such as substituted alkyl. W* is carboxyl, cyano or CHO.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: March 7, 2017
    Assignee: BAYER CROPSCIENCE AG
    Inventors: Birgit Kuhn, Lothar Willms, Thomas Frenzel, Klaus Bernhard Haaf, Stephen David Lindell, Hansjörg Dietrich, Dirk Schmutzler, Elmar Gatzweiler, Christopher Hugh Rosinger
  • SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND THEIR USE
    Publication number: 20170057954
    Abstract: The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
    Type: Application
    Filed: March 19, 2015
    Publication date: March 2, 2017
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Alexandros VAKALOPOULOS, Gaelle VALOT, Niels LINDNER, Markus FOLLMANN, Frank WUNDER, Johannes-Peter STASCH, Tobias MARQUARDT, Gorden REDLICH, Lisa DIETZ, Volkhart Min-Jian Ll
  • PROCESS FOR THE PREPARATION OF 4-CARBONYL)AMINO]-3-FLUOROPHENOXY}-N-ETHYLPYRIDINE-2-CARBOXAMIDE, ITS SALTS AND MONOHYDRATE
    Publication number: 20170057918
    Abstract: The present invention relates to a process for preparing 4-{4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy}-N-methylpyridine-2-carboxamide, its salts and monohydrate.
    Type: Application
    Filed: September 8, 2016
    Publication date: March 2, 2017
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Juergen STIEHL, Werner HEILMANN, Michael LÖGERS, Joachim REHSE, Michael GOTTFRIED, Saskia WICHMANN
  • ENANTIOMERS OF THE N-(2-AMINO-5-FLUORO-2-METHYLPENTYL)-8-[(2,6-DIFLUOROBENZYL)OXY]-2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXAMIDE, AS WELL AS OF THE DI- AND TRIFLUORO DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
    Publication number: 20170057958
    Abstract: The present application relates to novel 6-hydrogen-substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
    Type: Application
    Filed: April 29, 2015
    Publication date: March 2, 2017
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Alexandros Vakalopoulos, Markus Follmann, Johannes-Peter Stasch, Damian Brockschnieder, Frank Wunder, Tobias Marquardt, Lisa Dietz, Thomas Mondritzki, Dieter Lang, Volkhart Min-Jian Li
  • NOVEL T CELL RECEPTORS ANDIMMUNE THERAPY USING THE SAME
    Publication number: 20170055531
    Abstract: The present invention relates to novel compositions comprising certain pyrazolecarboxylic acid alkoxyamides according to formula (I) in combination with certain fungicides, to a process for preparing these compositions and to the use thereof as biologically active compositions, especially for the control of harmful microorganisms in plants and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: February 17, 2015
    Publication date: March 2, 2017
    Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Leonie ALTEN, Dominik MAURER, Steffen WALTER, Sebastian BUNK
  • Cotton variety FM 2322GL
    Patent number: 9578839
    Abstract: The cotton variety FM 2322GL is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and cotton lint as well as to hybrid cotton plants and seeds obtained by repeatedly crossing plants of variety FM 2322GL with other plants. The invention also relates to plants and varieties produced by the method of essential derivation from plants of FM 2322GL and to plants of FM 2322GL reproduced by vegetative methods, including but not limited to tissue culture of regenerable cells or tissue from FM 2322GL.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: February 28, 2017
    Assignee: BAYER CROPSCIENCE LP
    Inventors: David Becker, Margaret Shields, Craig Bednarz
  • Devices and methods for occluding a fallopian tube
    Patent number: 9579232
    Abstract: Devices and method for occluding a fallopian tube. The devices, in one embodiment, may include a plurality of expandable occluding members coupled by respective dissolvable connecting members.
    Type: Grant
    Filed: April 3, 2013
    Date of Patent: February 28, 2017
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Betsy Swann, Christopher A. Stout, Julian Cruzada, Vidya Gopal, Charlotte Hermanto
  • Use and application regimen of a pharmaceutical composition containing levonorgestrel and a COX inhibitor for on-demand contraception
    Patent number: 9579330
    Abstract: The invention relates to a method of hormonal female controlled “on demand” contraception, in which a pharmaceutical preparation comprising a COX inhibitor and levonorgestrel is taken on demand prior to expected sexual intercourse. Further subjects of the invention relate to pharmaceutical compositions and application regimes for “on demand” contraception.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: February 28, 2017
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Bernhard Lindenthal, Katrin Waellnitz, Peter Serno, Stefanie Lindemann, Ulrike Fuhrmann
  • IMIDAZO[1,2-A]PYRIDINES AS SOLUBLE GUANYLATE CYCLASE STIMULATORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
    Publication number: 20170050961
    Abstract: The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
    Type: Application
    Filed: April 29, 2015
    Publication date: February 23, 2017
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Alexandros VAKALOPOULOS, Gaelle VALOT, Markus FOLLMANN, Frank WUNDER, Johannes-Peter STASCH, Tobias MARQUARDT, Lisa DIETZ, Volkhart Min-Jian LI, Nicholas Charles RAY, Dominika BACHERA
  • IMIDAZO[1,2-A]PYRIDINES AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE FOR TREATING CARDIOVASCULAR DISEASES
    Publication number: 20170050962
    Abstract: The present application relates to novel heterocyclyl- and heteroaryl-substituted imidazo[1,2-a]pyridines, to processes for preparation thereof, to the use thereof, alone or in combinations, for the treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders.
    Type: Application
    Filed: April 29, 2015
    Publication date: February 23, 2017
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Alexandros VAKALOPOULOS, Markus FOLLMANN, Frank WUNDER, Johannes-Peter STASCH, Tobias MARQUARDT, Lisa DIETZ, Volkhart Min-Jian LI, Nicholas Charles RAY, Ines VUJASINOVIĆ