Patents Assigned to Bayer
  • Amides of acetic and propionic acids
    Patent number: 9433614
    Abstract: The invention relates to novel amides of acetic and propionic acids, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning ability and memory.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: September 6, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Joachim Luithle, Frank-Gerhard Bob, Christina Erb, Katrin Schnizler, Timo Flessner, Marja V. Kampen, Christoph Methfessel
  • Fluid mixing control device for a multi-fluid delivery system
    Patent number: 9433730
    Abstract: A fluid delivery system for use in medical procedures includes multiple fluid pump devices to deliver multiple injection fluids to a patient. The system includes a control unit controlling the fluid pump devices. An interactive visual display may be provided and electronically linked to the control unit so a user may select discrete mixture ratios of the first and the second of the multiple injection fluids to be delivered to the patient. A manual control device is operatively associated with the fluid pump devices and includes a housing and an actuator associated with the housing. Actuation of the actuator controls discrete flow rates of the selected discrete mixture ratio of the first and the second of the multiple injection fluids to the patient.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: September 6, 2016
    Assignee: Bayer HealthCare LLC
    Inventors: Ralph H Schriver, Michael Riley
  • Imidazo-, pyrazolopyrazines and imidazotriazines and their use
    Patent number: 9434731
    Abstract: The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: September 6, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stephan Siegel, Andreas Wilmen, Susanne Röhrig, Niels Svenstrup, Mark Jean Gnoth, Stefan Heitmeier, Ulrich Rester, Adrian Tersteegen, Michael Gerisch
  • Active compounds combination containing fluopyram and biologically control agent
    Patent number: 9433214
    Abstract: The present invention relates to active compound combinations and compostions for reducing the damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, nematodes or phytopathogens and which have fungicidal or nematicidal or insecticidal activity including any combination of the three activities, in particular within a composition, which comprises (A) Fluopyram, (B) a spore-forming bacterium of the genera Bacillus, selected from Bacillus firmus, Bacillus cereus, Bacillus pumilis, Bacillus amyloliquefaciens, Bacillus subtilis strain GB03, Bacillus subtilis strain QST713, and (C) at least one biological control agent, in particular bacteria, fungi or yeasts, protozoa, viruses, entomopathogenic nematodes, inoculants, botanicals and products produced by microorganisms including proteins or secondary to metabolites.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: September 6, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Elke Hellwege, Heike Hungenberg
  • Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis
    Patent number: 9433213
    Abstract: A composition comprising at least a pyridylethylbenzamide derivative of general formula (I) (a) and a compound capable of inhibiting the ergosterol biosynthesis (b) in a (a)/(b) weight ratio of from 0.01 to 20. A composition further comprising an additional fungicidal compound. A method for preventively or curatively combating the phytopathogenic fungi of crops by using this composition.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: September 6, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Marie-Claire Grosjean-Cournoyer, Jean-Marie Gouot
  • Heteroarylpiperidine and -piperazine derivatives as fungicides
    Patent number: 9434723
    Abstract: Heteroarylpiperidine and -piperazine derivatives of the formula (I) in which the symbols A, X, Y, L1, L2, G, Q, p, R1, R2 and R10 are each as defined in the description, and salts, metal complexes and N-oxides of the compounds of the formula (I), and the use thereof for controlling phytopathogenic harmful fungi and processes for preparing compounds of the formula (I).
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: September 6, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Tomoki Tsuchiya, Pierre Wasnaire, Sebastian Hoffmann, Pierre Cristau, Thomas Seitz, Joachim Kluth, Stefan Hillebrand, Juergen Benting, Daniela Portz, Ulrike Wachendorff-Neumann
  • Novel crystalline form of 2-piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenylmethanesulphonate
    Publication number: 20160251344
    Abstract: The present invention relates to a novel crystalline form of 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenylmethansulphonate, to processes for its preparation and to its use in agrochemical preparations.
    Type: Application
    Filed: October 13, 2014
    Publication date: September 1, 2016
    Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Britta OLENIK, Stefan HILLEBRAND, Pierre WASNAIRE, Martin WEISS, Ulrike WACHENDORFF-NEUMANN
  • A NOVEL STABLE FORMULATION
    Publication number: 20160250349
    Abstract: The present invention relates to a stable formulation particularly suitable for the anti-mesothelin immunoconjugate MF-T-SPDB-DM4. The described stable aqueous formulation comprising MF-T-SPDB-DM4 is directly suitable for therapeutic applications and for subsequent lyophilization. The lyophilized powder can be reconstituted with water to create a reconstituted solution which is again suitable for therapeutic applications. It is a further object to provide a stable reconstituted protein formulation which is suitable for therapeutic administrations.
    Type: Application
    Filed: October 21, 2014
    Publication date: September 1, 2016
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Carsten OLBRICH, Thomas TRILL
  • Overexpression of starch synthase in plants
    Patent number: 9428760
    Abstract: The present invention relates to a process for increasing the phosphate content of starches of genetically modified plant cells in comparison with starches from corresponding wild-type plant cells by introducing a foreign nucleic acid molecule which codes for a soluble starch synthase II. The present invention furthermore relates to the overexpression of this soluble starch synthase II in the genetically modified plant cells. Furthermore, the present invention relates to rice starch and rice flour with improved quality characteristics, to rice grains comprising this rice starch, and to rice plants on which these rice grains grow.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: August 30, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Claus Frohberg, Ralf-Christian Schmidt
  • Difluoromethyl-nicotinic- tetrahydronaphtyl carboxamides
    Patent number: 9428459
    Abstract: The present invention relates to novel difluoromethyl-nicotinic indanyl carboxamide compounds, to processes for preparing the carboxamide compounds, to compositions comprising the carboxamide compounds, and to the use thereof as biologically actives, especially for control of harmful microorganisms in crop protection and in the protection of materials.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: August 30, 2016
    Assignee: BAYER CROPSCIENCE AG
    Inventors: Simon Maechling, Alexander Sudau, Ulrike Wachendorff-Neumann, Christophe Dubost, David Bernier, Lionel Carles, Jean-Pierre Vors, Stephane Brunet, Helene Lachaise
  • Herbicidal agents containing aclonifen
    Patent number: 9426990
    Abstract: Herbicidal agents containing aclonifen. Herbicidal compositions having an effective amount of aclonifen and the other herbicides pendimethalin and picolinafen. These herbicidal compositions have an improved application profile.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: August 30, 2016
    Assignee: BAYER CROPSCIENCE AG
    Inventors: Dominique Schreiber, Thomas Wilde, Dirk Brueggemann
  • -[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products
    Patent number: 9428460
    Abstract: The invention relates to N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides, intermediates and methods for their production, use thereof for treating and/or preventing diseases and use thereof for producing medicinal products and use thereof for treating and/or preventing diseases, especially of hyperproliferative diseases.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: August 30, 2016
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Duy Nguyen, Hermann Künzer, Hortensia Faus Gimenez, Benjamin Bader, Silke Köhr, Martin Fritsch
  • Heteroaromatic amides and thioamides as pesticides
    Patent number: 9428487
    Abstract: The present application relates to novel amides and thioamides, to processes for preparation thereof and to use thereof for controlling animal pests, in particular arthropods and especially insects.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: August 30, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Thomas Bretschneider, Eva-Maria Franken, Ulrich Görgens, Martin Fusslein, Achim Hense, Joachim Kluth
  • Hydration prevention coating
    Patent number: 9427352
    Abstract: Occlusion devices and delivery systems are described in which a polymerizing oil is used to protect a hydrogel from premature swelling. In an embodiment, a delivery system includes an occlusion device releasably coupled within a catheter sheath. The occlusion device includes an expandable implant and a hydrogel. An at least partially oxidized polymerizing oil is inside a lumen of the catheter sheath between the distal end of the catheter sheath and the hydrogel.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 30, 2016
    Assignee: Bayer HealthCare LLC
    Inventor: Christopher A. Stout
  • SUBSTITUTED URACILS AS CHYMASE INHIBITORS
    Publication number: 20160244415
    Abstract: Substituted uracil derivatives of formula (I), processes for their preparation, their use alone or in combinations for the treatment and/or prophylaxis of diseases, and their use for preparing medicaments for the treatment and/or prophylaxis of diseases.
    Type: Application
    Filed: November 5, 2014
    Publication date: August 25, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Chantal Furstner, Jens Ackerstaff, Alexander Straub, Heinrich Meier, Hanna Tinel, Katja Zimmermann, Dmitry Zubov, Jens Schamberger
  • SUBSTITUTED PHENYLALANINE DERIVATIVES
    Publication number: 20160244437
    Abstract: The invention relates to substituted phenylalanine derivatives and to processes for preparation thereof, and to the use thereof for production of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and/or severe perioperative blood loss.
    Type: Application
    Filed: September 24, 2014
    Publication date: August 25, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Ulrike RÖHN, Manuel ELLERMANN, Julia STRASSBURGER, Astrid WENDT, Susanne RÖHRIG, Robert Alan WEBSTER, Martina Victoria SCHMIDT, Adrian TERSTEEGEN, Kristin BEYER, Martina SCHÄFER, Anja BUCHMÜLLER, Christoph GERDES, Michael SPERZEL, Steffen SANDMANN, Stefan HEITMEIER, Alexander HILLISCH, Jens ACKERSTAFF, Carsten TERJUNG
  • CYCLIC THIENOURACIL-CARBOXAMIDES AND USE THEREOF
    Publication number: 20160244461
    Abstract: The present application relates to novel 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide derivatives (“thienouracil”-carboxamides), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for the preparation of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiovascular disorders.
    Type: Application
    Filed: October 2, 2014
    Publication date: August 25, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Michael HÄRTER, Martina DELBECK, Bernd KALTHOF, Klemens LUSTIG, Niels LINDNER, Raimund KAST, Pierre WASNAIRE, Frank SÜßMEIER
  • Fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives and methods of use thereof
    Patent number: 9422263
    Abstract: The present invention relates to novel fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders.
    Type: Grant
    Filed: October 1, 2010
    Date of Patent: August 23, 2016
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Martin Michels, Markus Follmann, Alexandros Vakalopoulos, Katja Zimmermann, Nicole Teusch, Mario Lobell, Donald Bierer, Karen Engel, Maria Kissel
  • Use of aryl and hetaryl carboxamides as endoparasiticides
    Patent number: 9422276
    Abstract: The present application relates to known and novel aryl- and hetarylcarboxamides of the formula (I) and to their use as medicaments for controlling endoparasites in animals or humans, and also to parasiticidal compositions, in particular endoparasites, comprising aryl- and hetarylcyclylcarboxamides.
    Type: Grant
    Filed: November 23, 2012
    Date of Patent: August 23, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Hans-Georg Schwarz, Axel Trautwein, Lothar Willms, Maike Hink, Peter Lümmen, Ulrich Görgens, Pierre-Yves Coqueron, Achim Harder, Claudia Welz, Joerg Nico Greul
  • Substituted benzylpyrazoles
    Patent number: 9422268
    Abstract: Compounds of formula (I) and their use as pharmaceutical.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: August 23, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Marion Hitchcock, Anne Mengel, Anja Richter, Hans Briem, Knut Eis, Vera Pütter, Gerhard Siemeister, Stefan Prechtl, Amaury Ernesto Fernández-Montalván, Christian Stegmann, Simon Holton, Mark Jean Gnoth, Cornelia Preuβe