Patents Assigned to Bayer
  • Bicyclically substituted uracils and the use thereof
    Patent number: 9481672
    Abstract: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: November 1, 2016
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Chantal Fürstner, Jens Ackerstaff, Alexander Straub, Heinrich Meier, Hanna Tinel, Katja Zimmermann, Adrian Tersteegen, Dmitry Zubov, Raimund Kast, Jens Schamberger, Martina Schäfer, Kirsten Börngen
  • NOVEL INDAZOLECARBOXAMIDES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS COMPRISING THEM AND THEIR USE FOR PRODUCING MEDICAMENTS
    Publication number: 20160311833
    Abstract: The present application relates to novel 6-substituted indazoles having a carboxamide side chain, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of endometriosis, lymphomas, macular degeneration, COPD and psoriasis.
    Type: Application
    Filed: December 16, 2014
    Publication date: October 27, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Ulrich BOTHE, Holger SIEBENEICHER, Nicole SCHMIDT, Andrea ROTGERI, Ulf BÖMER, Sven RING, Horst IRLBACHER, Judith GÜNTHER, Holger STEUBER, Martin LANGE, Martina SCHÄFER
  • ADENOSINE A1 AGONISTS AS MEDICAMENTS FOR KIDNEY DISORDERS
    Publication number: 20160311812
    Abstract: The present application relates to selective partial adenosine A1 receptor agonists of the formula (I) and their use for treating and/or preventing diseases and to their use for preparing medicaments for treating and/or preventing diseases, preferably for treating and/or preventing acute and/or chronic kidney disorders (primary disorder and secondary disorder) with and without concomitant acute and/or chronic heart disorders.
    Type: Application
    Filed: December 9, 2014
    Publication date: October 27, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Barbara ALBRECHT-KÜPPER, Kirsten LEINEWEBER, Axel KRETSCHMER, Daniel MEIBOM, Alexandros VAKALOPOULOS, Nicole DIEDRICHS, Katja ZIMMERMANN
  • Substituted benzothienyl-pyrrolotriazines and uses thereof
    Patent number: 9475815
    Abstract: This invention relates to novel substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: October 25, 2016
    Assignee: BAYER INTELLETUAL PROPERTY GMBH
    Inventors: Mario Lobell, Walter Hübsch, Hartmut Schirok, Mélanie Héroult, Dirk Brohm, Marie-Pierre Collin, Sylvia Grünewald, Klemens Lustig, Ulf Bömer, Verena Voehringer, Niels Lindner
  • plant comprising a mutant INDEHISCENT allele
    Patent number: 9475849
    Abstract: This invention relates to crop plants of which the fruit dehiscence properties are modulated. More specifically the invention relates to improved methods and means for reducing seed shattering, or delaying seed shattering until after harvest, in plants, while maintaining at the same time an agronomically relevant threshability of the pods.
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: October 25, 2016
    Assignee: Bayer CropScience N.V.
    Inventors: Benjamin Laga, Bart den Boer, Bart Lambert
  • Cyanoenamines and their use as fungicides
    Patent number: 9474275
    Abstract: The present invention relates to cyanoenamine derivatives, their process of preparation, intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants and in material protection, using these compounds or compositions.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: October 25, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Jürgen Benting, Ulrike Wachendorff-Neumann, Philippe Desbordes, Christophe Dubost, Pierre Genix, Shinichi Narabu, Jean-Pierre Vors
  • Multi-fluid medical injector system and methods of operation
    Patent number: 9474857
    Abstract: A multi-fluid injector system and methods of operation thereof are presented. One embodiment of such a fluid injector system includes an automatic refill procedure for a fluid injector system comprising a fluid injector and an operably engaged syringe. The procedure includes the step of determining, using an electronic control device operably controlling the fluid injector system, whether a fluid injection procedure involving the syringe is impending. If the electronic control device determines that the fluid injection procedure is not impending, such that the automatic refill will not interfere with the fluid injection procedure, an automatic refill of the syringe is initiated.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: October 25, 2016
    Assignee: Bayer HealthCare LLC
    Inventors: Michael A. Riley, Ralph H. Schriver, William D. Barlow, Thomas P. Joyce, Andreas Maihoefer
  • Substituted oxopyridine derivatives and use thereof as factor xia/plasma
    Patent number: 9475809
    Abstract: The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: October 25, 2016
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Susanne Röhrig, Alexander Hillisch, Julia Straβburger, Stefan Heitmeier, Martina Victoria Schmidt, Karl-Heinz Schlemmer, Anja Buchmüller, Christoph Gerdes, Henrik Teller, Martina Schäfer, Adrian Tersteegen
  • Combination Therapy Of Substituted Oxazolidinones
    Publication number: 20160303138
    Abstract: The present invention relates to combinations of A) oxazolidinones of the formula (I) with B) acetylsalicylic acid (aspirin) and C) an ADP receptor antagonist, in particular P2Y12 purinoreceptor blocker, to a process for producing these combinations and to the use thereof as medicaments, in particular for the prophylaxis and/or treatment of thromboembolic disorders.
    Type: Application
    Filed: June 23, 2016
    Publication date: October 20, 2016
    Applicant: Bayer Intellectual Property GMBH
    Inventor: Elisabeth Perzborn
  • PREPARATION OF HALOGENATED DI-SUBSTITUTED BENZYLAMINES, PARTICULARLY HALOGENATED DIALKYLBENZYLAMINES
    Publication number: 20160304435
    Abstract: The present invention relates to a novel process for preparing halogenated di-substituted benzylamines, particularly halogenated dialkylbenzylamines.
    Type: Application
    Filed: December 8, 2014
    Publication date: October 20, 2016
    Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Johann SEEBA, Günter SCHLEGEL, Martin LITTMANN, Rafael WARSITZ, Mark James FORD
  • SUBSTITUTED PIPERIDINYLTETRAHYDROQUINOLINES
    Publication number: 20160304491
    Abstract: The present application relates to novel substituted piperidinyltetrahydroquinolines, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disorders, peripheral and cardial vascular disorders, thromboembolic disorders and ischaemias, peripheral circulatory disturbances, Raynaud's phenomenon, CREST syndrome, microcirculatory disturbances, intermittent claudication, and peripheral and autonomous neuropathies.
    Type: Application
    Filed: December 16, 2014
    Publication date: October 20, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Eva Maria BECKER-PELSTER, Philipp BUCHGRABER, Anja BUCHMÜLLER, Karen ENGEL, Volker GEISS, Andreas GÖLLER, Herbert HIMMEL, Raimund KAST, Andreas KNORR, Dieter LANG, Gorden REDLICH, Carsten SCHMECK, Hanna TINEL, Frank WUNDER
  • SUBSTITUTED BIPIPERIDINYL DERIVATIVES
    Publication number: 20160304492
    Abstract: The invention relates to novel substituted bipiperidinyl derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disorders, peripheral and cardial vascular disorders, thromboembolic disorders and ischaemias, peripheral circulatory disturbances, Raynaud's phenomenon, CREST syndrome, microcirculatory disturbances, intermittent claudication, and peripheral and autonomous neuropathies.
    Type: Application
    Filed: December 16, 2014
    Publication date: October 20, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Eva Maria BECKER-PELSTER, Philipp BUCHGRABER, Anja BUCHMÜLLER, Karen ENGEL, Andreas GÖLLER, Herbert HIMMEL, Raimund KAST, Joerg KELDENICH, Carsten SCHMECK, Hanna TINEL, Frank WUNDER
  • Counter-flow combustor
    Patent number: 9470420
    Abstract: Counterflow burner having a combustion chamber (5) to which combustible gas (B) and an oxidising agent (0) can be fed from opposite sides, having three planar substrates (1, 2, 3) which are interconnected, lying one above the other, the middle substrate (2) having the combustion chamber (5), from which passages (4), lying in the plane of the substrate, lead to the edge, the upper substrate (3) and the lower substrate (1) being closed, and at least the middle substrate (2) is produced using methods of microsystem technology.
    Type: Grant
    Filed: July 21, 2010
    Date of Patent: October 18, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Jörg Müller, Winfred Kuipers
  • Imidazopyrazines
    Patent number: 9468642
    Abstract: The present invention relates to imidazopyrazine compounds of general Formula (I): in which X, R1, R2, R3a, R3b, R4a, R4b, R4C, and R4D are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: October 18, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Ulrich Klar, Marcus Koppitz, Dirk Kosemund, Rolf Bohlmann, Benjamin Bader, Philip Lienau, Gerhard Siemeister, Stefan Prechtl, Duy Nguyen, William Scott
  • Fungicide N-cycloalkyl-N-bicyclicmethylene-carboxamide derivatives
    Patent number: 9468211
    Abstract: The present invention relates to N-cycloalkyl-N-bicyclicmethylene-carboxamide or thiocarboxamide derivatives, their process of preparation, preparation of intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.
    Type: Grant
    Filed: March 25, 2013
    Date of Patent: October 18, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Jurgen Benting, Peter Dahmen, Philippe Desbordes, Stephanie Gary, Helene Lachaise, Philippe Rinolfi, Ulrike Wachendorff-Neumann
  • System and Method for Medical Fluid Identification and Verification
    Publication number: 20160296692
    Abstract: A system for injecting fluid to a patient is provided. The system provides manual or automatic verification and identification of the fluid to be injected, prior to, during or after injection. The system includes: a fluid having at least one active compound and at least one tracer compound; an injector configured to deliver the fluid to the patient through a fluid path set; at least one sensor coupled to at least one of the syringe, the injector, or the patient, configured to measure at least one property of the tracer in the fluid, and a feedback path to adjust at least one injection parameter of the injector based on at least one measurement from the at least one sensor.
    Type: Application
    Filed: November 25, 2014
    Publication date: October 13, 2016
    Applicant: BAYER MEDICAL CARE INC.
    Inventors: Jacob Agris, III, Arthur E. Uber, III, Ralph H. Schriver, Evelina Zapatka, Michael A. Spohn
  • ALS INHIBITOR HERBICIDE TOLERANT MUTANT PLANTS
    Publication number: 20160298129
    Abstract: The present invention relates to an ALS inhibitor herbicide tolerant crop plants, such as allotetraploid Brassica plants, such as B. napus plants, progeny and parts thereof comprising mutations in acetolactase genes.
    Type: Application
    Filed: December 1, 2014
    Publication date: October 13, 2016
    Applicants: BAYER CROPSCIENCE NV, BAYER CROPSCIENCE LP
    Inventors: Rene RUITER, Rudiger HAIN, Gerhard JOHANN, Bernd LABER, Bart LAMBERT
  • SUBSTITUTED TRIAZOLOPYRIDINES
    Publication number: 20160297811
    Abstract: The present invention relates to substituted triazolopyridine compounds of general formula (I); in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.
    Type: Application
    Filed: June 3, 2014
    Publication date: October 13, 2016
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Hartmut SCHIROK, Volker SCHULZE, Dirk KOSEMUND, Hans BRIEM, Benjamin BADER, Ulf BÖMER, Antje Margret WENGNER, Gerhard SIEMEISTER, Philip LIENAU
  • SUBSTITUTED URACILS AND USE THEREOF
    Publication number: 20160297771
    Abstract: The present application relates to novel substituted uracil derivatives of formula (I), to a method for the production thereof, to the use thereof either alone or in combination for treating and/or preventing diseases, and to the use thereof for producing pharmaceuticals for the treatment and/or prevention of diseases.
    Type: Application
    Filed: November 5, 2014
    Publication date: October 13, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Chantal FÜRSTNER, Jens ACKERSTAFF, Alexander STRAUB, Heinrich MEIER, Hanna TINEL, Katja ZIMMERMANN, Adrian TERSTEEGEN, Dmitry ZUBOV, Raimund KAST, Jens SCHAMBERGER, Martina SCHÄFER
  • Sprayer with wand
    Patent number: D769412
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: October 18, 2016
    Assignee: BAYER CROPSCIENCE LP
    Inventors: Valerie M. Henshaw, Kenneth Krause