Patents Assigned to Bayer
  • 5-phenyl-substituted N-(tetrazol-5-yl) aryl carboxylic acid amides and N-(triazol-5-yl) aryl carboxylic acid amides, and use thereof as herbicides
    Patent number: 9259001
    Abstract: 5-phenyl-substituted N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamides of the general formula (I) are described as herbicides. In this formula (I), W, X, Y, Z and R are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen. A and B are N and CY.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: February 16, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Ralf Braun, Hartmut Ahrens, Andreas Van Almsick, Stefan Lehr, Isolde Häuser-Hahn, Hansjörg Dietrich, Elmar Gatzweiler, Ines Heinemann, Christopher Hugh Rosinger
  • Method of improving grass quality
    Patent number: 9259004
    Abstract: The invention relates to a method of improving grass quality comprising applying an effective amount of a composition containing a phthalocyanine to the grass in the substantial absence of phosphorous acid, monoalkyl esters of phosphorous acid, or salts thereof.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: February 16, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Lawrence H. Norton, Richard Hanrahan, David R. Spak
  • Method for producing nitrobenzene by adiabatic nitriding
    Patent number: 9260377
    Abstract: The invention provides a continuous adiabatic process for the preparation of nitrobenzene by nitrating benzene with mixtures of sulfuric and nitric acids using a stoichiometric excess of benzene, wherein the content of organic compounds in the circulating sulfuric acid, at least during the start-up period of the production plant, is always kept below 1.0 mass percent, based on the total mass of circulating sulfuric acid. This is preferably achieved by a procedure in which, either after the end or before the beginning of a production cycle, the circulating sulfuric acid is circulated at elevated temperature so that the organics contained in the sulfuric acid, preferably comprising nitrobenzene and traces of benzene, dinitrobenzene and nitrophenols, are separated off in the evaporation apparatus for concentrating the sulfuric acid.
    Type: Grant
    Filed: July 23, 2013
    Date of Patent: February 16, 2016
    Assignee: Bayer MaterialScience AG
    Inventors: Thomas Knauf, Michael Merkel, Antoni Mairata
  • Process for the preparation of substituted N-(benzyl)cyclopropanamines by imine hydrogenation
    Patent number: 9260378
    Abstract: The present invention relates to a process for the preparation of substituted N-(benzyl)cyclopropanamines of the general formula (II) starting from N-[(aryl)methylene]cyclopropanamine derivatives. The present invention further provides the N-[(aryl)methylene]cyclopropanamine derivatives used as starting compounds in this process according to the invention, and their use for the preparation of substituted N (benzyl)cyclopropanamines.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: February 16, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Norbert Lui, Wahed Ahmed Moradi, Thomas Norbert Muller
  • Dosing device and method for dosing and dispensing by means of the dosing device
    Patent number: 9261394
    Abstract: The invention relates to a dosing device comprising a storage container and a storage chamber disposed therein, a dosing container and a dosing chamber disposed therein, and a dosing connection between the storage chamber and the dosing chamber.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: February 16, 2016
    Assignee: BAYER CROPSCIENCE AG
    Inventor: Fabrice Moreau
  • Substituted benzylpyrazoles
    Patent number: 9260412
    Abstract: Compounds of formula (I) and their use as pharmaceutical.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: February 16, 2016
    Assignees: BAYER INTELLECTUAL PROPERTY GMBH, BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Marion Hitchcock, Anne Mengel, Anja Richter, Hans Briem, Knut Eis, Vera Pütter, Gerhard Siemeister, Stefan Prechtl, Amaury Ernesto Fernández-Montalván, Christian Stegmann, Simon Holton, Mark Jean Gnoth, Cornelia Preuβe
  • Electrochemical test sensor and method of making the same
    Patent number: 9261479
    Abstract: An electrochemical test sensor being adapted to assist in determining information relating to an analyte in a fluid sample and includes a base and a second layer. The base includes a plurality of electrodes, a working conductive lead and a counter conductive lead thereon. The electrodes include a working electrode and a counter electrode. The second layer assists in forming a channel in which the channel includes a reagent therein. Auto-calibration information of the test sensor is performed by a plurality of auto-calibration segments connected to one of the following: the working conductive lead, the counter conductive lead, or neither of the conductive leads, at least one of the plurality of auto-calibration segments being connected to the working conductive lead and at least one of the plurality of auto-calibration segments being connected to the counter conductive lead.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: February 16, 2016
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Harris A. Lieber, Joseph E. Perry
  • Insecticides based on neonicotinoids and safeners
    Patent number: 9259003
    Abstract: Insecticidal compositions, characterized by an effective amount of a combination of active compounds comprising (a) at least one compound of the formula (I) in which Het, A, R and X are as defined in the description, and (b) at least one crop plant compatibility-improving compound from the group of compounds listed in the description, which are used for controlling arthropods, and also methods for controlling arthropods by treating plants and their seed with the compositions.
    Type: Grant
    Filed: July 18, 2005
    Date of Patent: February 16, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Reiner Fischer, Wolfram Andersch, Heike Hungenberg, Wolfgang Thielert, Lothar Willms
  • Fluid delivery system with high and low pressure hand manifold
    Patent number: 9259527
    Abstract: A fluid delivery system is provided and includes a power injector supporting a high pressure syringe. The fluid delivery system further includes a manifold and a low pressure hand-operated syringe. The manifold generally includes a plurality of fluid control valves in series fluid communication. A first fluid control valve of the plurality of fluid control valves has a first port, a second inlet port, and a third port. The third port of the first fluid control valve is in fluid connection with a first port of a second fluid control valve. The low pressure hand-operated syringe is in fluid connection with the first port of the first fluid control valve, and the high pressure syringe is in fluid connection with the second port of the first fluid control valve. The fluid control valves may be multi-position stopcock valves.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: February 16, 2016
    Assignee: Bayer HealthCare LLC
    Inventors: Michael A Spohn, Michael James Swantner, Barry Lynn McDaniel
  • Method for producing polycarbonate polyols by the immortal polymerization of cyclic carbonates
    Patent number: 9260562
    Abstract: The invention relates to a process for the preparation of polycarbonate polyols, characterized in that cyclic carbonates are polymerized in the presence of DMC catalysts and chain-transfer agents consisting of polyether carbonate polyols.
    Type: Grant
    Filed: November 3, 2011
    Date of Patent: February 16, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Thomas Ernst Müller, Christoph Gürtler, Anthony Kermagoret, Yvonne Dienes, Igor Busygin, Burkhard Köhler, Walter Leitner, Ganna Lyashenko
  • Herbicidal composition for tolerant or resistant cereal crops
    Patent number: 9253985
    Abstract: The invention provides herbicide combinations and the use of herbicide combinations for controlling harmful plants in cereal crops wherein the herbicide combination in question comprises (A) a herbicide from the group of glufosinate derivatives of the formula (A1) in which Z represents hydroxyl, —NHCH(CH3)CONHCH(CH3)COOH or —NHCH(CH3)CONHCH[CH2CH(CH3)2]COOH, or an ester or salt thereof, and (B) a herbicide from the group of carboxylic acid derivatives of the formula (B1) in which X represents N or CH and R represents CO2H or a herbicidally active derivative thereof, and the cereal crops are tolerant, if appropriate in the presence of safeners, to the herbicides (A) and (B) present in the combination.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: February 9, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Erwin Hacker, Hansjörg Dietrich, Hubert Menne, Elmar Gatzweiler, Frank Ziemer
  • Substituted imidazopyridazines
    Patent number: 9255100
    Abstract: The present invention relates to substituted imidazopyridazine compounds of general formula (I), which are Mps-1 (Monopolar Spindle 1) Kinase inhibitors (also known as Tyrosine Threonine Kinase, TTK) in which R3, R5, and A are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: February 9, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Ulrich Klar, Marcus Koppitz, Rolf Jautelat, Dirk Kosemund, Rolf Bohlmann, Philip Lienau, Gerhard Siemeister, Antje Margret Wengner
  • Method for activation and conjugation of biomolecules
    Patent number: 9254336
    Abstract: The present invention is directed to a method for producing a biomolecule conjugate where the method is integrated into a single unit operation.
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: February 9, 2016
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Jens H. Vogel, Chi Shung Brian To, Carolina Lucia Bianco
  • Fungicide active substance combinations
    Patent number: 9253982
    Abstract: The novel active compound combinations comprising 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione of the formula and the active compound of groups (1) to (24) listed in the description have very good fungicidal properties.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: February 9, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stefan Dutzmann, Klaus Stenzel, Manfred Jautelat
  • AN INTELLIGENT AND CONFIGURABLE FLUID DELIVERY SYSTEM AND METHODS FOR ITS USE
    Publication number: 20160030662
    Abstract: A configurable fluid delivery system and methods for its use are disclosed. The system may include one or more control units, fluid delivery units, fluid actuator units, and disposable units. Data sources and sensors on each of the delivery units, actuator units, and disposable units may provide data to the control unit, thereby identifying the components along with the manner in which they may be configured. The control unit may notify a user regarding the status of any one or more of the delivery, actuator, and disposable units to indicate their appropriateness for delivering a fluid according to one or more selected procedures and protocols. Also disclosed are methods by which the configurable fluid delivery system may provide data to a user to assist the user in assembling and testing a particular configuration of the fluid delivery system for a specific use.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Applicant: BAYER MEDICAL CARE INC.
    Inventors: ARTHUR E. UBER, III, MARK TROCKI
  • NOVEL TRIAZOLINTHIONE DERIVATIVES
    Publication number: 20160031851
    Abstract: The present invention relates to novel triazolinthione derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: April 9, 2014
    Publication date: February 4, 2016
    Applicant: Bayer Cropscience Aktiengesellschaft
    Inventors: Sebastian HOFFMANN, Alexander SUDAU, Peter DAHMEN, Ulrike WACHENDORFF-NEUMANN, David BERNIER, Helene LACHAISE, Stephane BRUNET, Jacky VIDAL, Pierre GENIX, Pierre-Yves COQUERON, Julie GEIST, Jean-Pierre VORS, Philippe KENNEL, Ricarda MILLER
  • METHOD FOR COMBATING PESTS
    Publication number: 20160029631
    Abstract: Method for improving the utilization of the production potential of transgenic soybean plants in the absent of a pest and a method for controlling/combating/treating pests by treating Bt-soybean plants with at least one compound of I-1 to I-4.
    Type: Application
    Filed: April 15, 2014
    Publication date: February 4, 2016
    Applicant: Bayer Cropscience Aktiengesellschaft
    Inventors: Elke HELLWEGE, Koen VAN DEN EYNDE
  • VARIANT FACTOR VIII POLYPEPTIDES AND METHODS OF THEIR PRODUCTION AND USE
    Publication number: 20160031968
    Abstract: This disclosure relates to variant Factor VIII polypeptides comprising an amino acid substitution at one or more positions within one or both of the thrombin cleavage site and the activation loop. In certain embodiments, the variant Factor VIII polypeptide comprises one or more amino acid substitutions within both the thrombin cleavage site and the activation loop. In further embodiments, the variant factor VIII polypeptide further comprises one or more amino acid substitutions within the A1-A2 domain interface and the A2-A3 domain interface. The present disclosure further relates to methods of producing and/or using such variant Factor VIII polypeptides; nucleic acids encoding the polypeptides; vectors and/or recombinant cells, tissues, or organisms containing such nucleic acids; and kits and pharmaceutical compositions containing such polypeptides and/or nucleic acids.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Uwe GRITZAN, Peter KRETSCHMER, Lilley LEONG, Chandra PATEL
  • RECOMBINANT FACTOR VIII FORMULATIONS
    Publication number: 20160030524
    Abstract: Provided are liquid and lyophilized recombinant Factor VIII formulations, including formulations for polymer-conjugated FVIII such as PEGylated Factor VIII.
    Type: Application
    Filed: March 11, 2014
    Publication date: February 4, 2016
    Applicant: BAYER HEALTHCARE LLC
    Inventors: De Qian WANG, Xinghang MA, Nelly TSVETKOVA
  • Compositions containing factor VIII glycoforms
    Patent number: 9249209
    Abstract: The invention concerns glycosylated proteins having human factor VIII activity. In a preferred embodiment, the protein is glycosylated with oligosaccharides that include an alpha-(2,6)-linked sialic acid and a bisecting GlcNAc linked to a core beta-mannose.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: February 2, 2016
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Myung-Sam Cho, Sham-Yuen Chan