Patents Assigned to Bayer
  • Process for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses
    Patent number: 9242934
    Abstract: The present invention relates to processes for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses. The invention further relates to a process for the preparation of compounds of formula (4): where a mixture of an aniline (compound of formula Q) is reacted with a thioether (compound of formula W): in the presence of a chlorinating agent and an organic solvent at a reaction temperature in the range above ?65° C.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: January 26, 2016
    Assignee: BAYER CROPSCIENCE AG
    Inventors: Mark James Ford, Gunter Karig
  • ARYL UREAS WITH ANGIOGENISIS INHIBITING ACTIVITY
    Publication number: 20160015697
    Abstract: This invention relates to methods of using aryl ureas to treat diseases mediated by the VEGF induced signal transduction pathway characterized by abnormal angiogenesis or hyperpermeability processes.
    Type: Application
    Filed: July 18, 2014
    Publication date: January 21, 2016
    Applicant: Bayer Healthcare LLC
    Inventors: Jacques Dumas, William Scott, James Elting, Holia Hatoum-Makdad
  • METHOD FOR PRODUCING LIGHT-COLOURED TDI-POLYISOCANTES
    Publication number: 20160017097
    Abstract: The invention relates to polyisocyanates comprising urethane groups, based on toluylene diisocyanate, to a method for their production, and to their use as the polyisocyanate component in one- and two-component polyurethane coatings.
    Type: Application
    Filed: March 7, 2014
    Publication date: January 21, 2016
    Applicant: BAYER MATERIALSCIENCE AG
    Inventors: Josef SANDERS, Andreas HECKING, Reinhard HALPAAP, Frank RICHTER, Oswald WILMES, Jan BUSCH, Tim LODDENKEMPER, Friedhelm STEFFENS
  • Methods of determining analyte concentration having enhanced stability and hematocrit performance
    Patent number: 9239312
    Abstract: The present invention relates to methods of determining the concentration of an analyte in a sample or improving the performance of a concentration determination. The electrochemical sensor strips may include at most 8 ?g/mm2 of a mediator. The strips, the strip reagent layer, or the methods may provide for the determination of a concentration value having at least one of a stability bias of less than ±10% after storage at 50° C. for 4 weeks when compared to a comparison strip stored at ?20° C. for 4 weeks, a hematocrit bias of less than ±10% for whole blood samples including from 20 to 60% hematocrit, and an intercept to slope ratio of at most 20 mg/dL.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: January 19, 2016
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Huan-Ping Wu, Christine D. Nelson, Hope Spradlin, Eric Maurer
  • System and apparatus for modeling pressures generated during an injection procedure
    Patent number: 9238099
    Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a pressure modeling system adapted to predict a pressure to be generated at one or more points in the injection fluid path during planned injection procedure based upon variables associated with an injection protocol.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: January 19, 2016
    Assignee: Bayer HealthCare LLC
    Inventors: John F. Kalafut, David A. Mishler
  • Polymer comprising a plurality of phenothiazine groups and methods of making the same
    Patent number: 9238717
    Abstract: A non-leaching mediator may include a polymer comprising the general formula (VIII): and salts thereof, where R? is an organic group, m is 0 or 1, n is about 9, and x and y independently are an integer from 1 to 10,000.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: January 19, 2016
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Jiangfeng Fei, William Chiang, Frank Kerrigan, Stuart Green, Craig Robson, Howard Easterfield
  • Process for the production of polyurethane composite components
    Patent number: 9238320
    Abstract: A composite and process for the production of a composite component, comprising a) a support of a thermoplastic composition, and b) at least one polyurethane layer in direct contact with the support.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: January 19, 2016
    Assignee: BAYER MATERIALSCIENCE AG
    Inventors: Andreas Seidel, Rainer Protte, Eckhard Wenz, Uli Franz, Philipp Moeller
  • Hydroxylamino polymer and method for the production thereof
    Patent number: 9238711
    Abstract: The present invention relates to a process for the preparation of a hydroxy-amino polymer, comprising the steps: a) reacting an H-functional starter compound carrying at least one Zerewitinoff-active H atom with an unsaturated cyclic carboxylic acid anhydride to give a carboxyl-group-carrying prepolymer, b) reacting the carboxyl-group-carrying prepolymer with at least one epoxide compound to give a hydroxyl-group-carrying prepolymer, c) adding a primary amine and/or ammonia to the double bond of the hydroxyl-group-carrying prepolymer obtained according to step b) to give the hydroxy-amino polymer, wherein the ratio of the amount of carboxylic acid anhydride to the number of Zerewitinoff-active H atoms of the H-functional starter compound is so chosen that almost all the Zerewitinoff-active H atoms of the H-functional starter compound are reacted.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: January 19, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Jorg Hofmann, Klaus Lorenz, Hartmut Nefzger
  • NOVEL HALOGEN-SUBSTITUTED COMPOUNDS
    Publication number: 20160007604
    Abstract: The invention relates inter alia to halogen-substituted compounds of the general formula (II) in which the radicals A1-A4, T, n, W, Q, R1 and Z1-Z3 have the meanings given in the description. Also described are processes for preparing the compounds of the formula (II). The compounds according to the invention are particularly suitable for controlling insects, arachnids and nematodes in agriculture and ectoparasites in veterinary medicine.
    Type: Application
    Filed: February 27, 2014
    Publication date: January 14, 2016
    Applicant: BAYER ANIMAL HEALTH GMBH
    Inventors: Michael MAUE, Anne DECOR, Thomas BRETSCHNEIDER, Julia Johanna HAHN, Werner HALLENBACH, Reiner FISCHER, Hans-Georg SCHWARZ, Ulrich GÖRGENS, Kerstin ILG, Klaus RAMING, Johannes KÖBBERLING, Walter HÜBSCH, Andreas TURBERG
  • METHOD FOR THE PRODUCTION OF ABS COMPOSITIONS HAVING AN IMPROVED SURFACE
    Publication number: 20160009870
    Abstract: The invention relates to a method for producing compositions containing vinylaromatic copolymers which are obtained in an emulsion polymerization process and comprise production-related salt inclusions. Said compositions are characterized by an improved surface quality once the granulates have been moistened by bringing same in contact with liquid water and have been stored in said water, thus making the compositions suitable for producing molded articles having a class A surface that remains flawless over time.
    Type: Application
    Filed: February 5, 2014
    Publication date: January 14, 2016
    Applicant: BAYER MATERIAL SCIENCE AG
    Inventors: Hans-Juergen THIEM, Ingmar HERMSDORFER, Birgit MANNEL, Andreas SEIDEL, Eckhard WENZ, Hans-Juergen KLANKERS, Udo BIRKENBEUL, Alfred SATZINGER
  • METAL CHELATE COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA
    Publication number: 20160008490
    Abstract: The present invention is directed to compounds that bind to glycoprotein IIb/IIIa and can be used for diagnostic imaging, in particular magnetic resonance imaging of thrombi. The disclosed compounds enable the binding to glycoprotein IIb/IIIa receptor combined with an adequate relaxivity.
    Type: Application
    Filed: February 11, 2014
    Publication date: January 14, 2016
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: MARKUS BERGER, JESSICA LOHRKE, GREGOR JOST, MICHAEL REINHARDT
  • PYRROLO- AND PYRAZOLO-TRIAZOLODIAZEPINES AS BET-PROTEIN INHIBITORS FOR TREATING HYPERPROLIFERATIVE DISEASES
    Publication number: 20160009725
    Abstract: What is described are BET protein-inhibitory, especially BRD2-, BRD3- and BRD4-inhibitory, bicyclo- and spino-substituted pyrrolo- and pyrazolodiazepines of the general formula I in which X, Y, n, m, R1, R2, R3, R4 and R5 are each as defined in the description, to intermediates for preparation of the inventive compounds, to pharmaceutical compositions comprising the inventive compounds, and to the prophylactic and therapeutic use thereof for hyperproliferative disorders, especially for tumour disorders. Also described is the use of the compounds according to the invention as BET protein inhibitors for benign hyperplasias, for atherosclerotic disorders, for sepsis, for autoimmune disorders, for vascular disorders, for viral infections, for neurodegenerative disorders, for inflammatory disorders, for atherosclerotic disorders and for male fertility control.
    Type: Application
    Filed: February 17, 2014
    Publication date: January 14, 2016
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Norbert SCHMEES, Bernd BUCHMANN, Bernard HAENDLER, Roland NEUHAUS, Pascale LEJEUNE, Martin KRÜGER, Amaury Ernesto FERNANDEZ-MONTALVAN, Hermann KÜNZER
  • MICRO-PLATE ELECTRODE CELL AND USE THEREOF
    Publication number: 20160009575
    Abstract: The invention relates to an electrolysis cell for the particularly efficient treatment of wastewater polluted with organic substances by electrooxidative degradation of the wastewater constituents contributing to the chemical oxygen demand, and also its use.
    Type: Application
    Filed: February 24, 2014
    Publication date: January 14, 2016
    Applicants: BAYER CROPSCIENCE AKTIENGESELLSCHAFT, BAYER TECHNOLOGY SERVICES GMBH
    Inventors: Jens AßMANN, Johannes LEONHÄUSER, Ivonne GÖRTZ, Christian RÄMSCH, Frank HERBSTRITT
  • SUBSTITUTED THIAZOLOPYRIMIDINES
    Publication number: 20160009734
    Abstract: The present invention relates to substituted thiazolopyrimidine compounds of general formula I as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: March 6, 2014
    Publication date: January 14, 2016
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Ulrich KLAR, Lars WORTMANN, Keith GRAHAM, Florian PUEHLER, Detlev SÜLZLE, Georg KETTSCHAU, Philip LIENAU
  • Systems and method of delivering fluids to a patient of varying concentration
    Patent number: 9233176
    Abstract: A method for injection of an imaging contrast into a patient, includes: a. in a first phase, injecting a fluid having a first concentration of contrast agent for a first period of time; and b. in a second phase, injecting a fluid having a second concentration of contrast agent for a second period of time. The osmolarity of the second phase is higher than the osmolarity of the first phase. The method can further include: c. in a third phase, subsequent to the second phase, injecting a fluid having a third concentration of contrast agent for a third period of time. The osmolarity of the third phase is lower than the osmolarity of the second phase. In embodiments in which the composition of the contrast agent of the third phase is the same as the composition of the contrast agent of the second phase, the third concentration can be lower than the second concentration.
    Type: Grant
    Filed: June 6, 2007
    Date of Patent: January 12, 2016
    Assignee: Bayer HealthCare LLC
    Inventors: Ruediger Lawaczek, John F. Kalafut
  • N-[(het)arylethyl)] pyrazole(thio)carboxamides and their heterosubstituted analogues
    Patent number: 9232799
    Abstract: The present invention relates to fungicidal N-[(het)arylethyl)] pyrazolecarboxamide or thiocarboxamide and their heterosubstituted analogues, their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: January 12, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Jurgen Benting, Christoph Braun, Pierre-Yves Coqueron, Pierre Cristau, Peter Dahmen, Philippe Desbordes, Stephanie Gary, Jorg Greul, Hiroyuki Hadano, Thomas Knobloch, Ruth Meissner, Ulrike Wachendorff-Neumann, Lothar Willms
  • Plant growth regulator
    Patent number: 9232791
    Abstract: The invention relates to the use of one or more acylsulfonamide safener compounds of formula (I): for modifying plant development of useful plants. The use provides an increase in root growth and/or a regulation in shoot growth of the plants.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: January 12, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Christopher Hugh Rosinger, Frank Ziemer
  • Heterocyclic compounds as pesticides
    Patent number: 9233951
    Abstract: The present invention relates to novel heterocyclic compounds, to processes for preparation thereof and to the use thereof for controlling animal pests, which include arthropods and especially insects.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: January 12, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Friedrich August Mühlthau, Thomas Bretschneider, Reiner Fischer, Martin Füβlein, Markus Heil, Achim Hense, Joachim Kluth, Adeline Köhler, Eva-Maria Franken, Olga Malsam, Arnd Voerste, Peter Jeschke, Angela Becker, Peter Lösel, Yoshitaka Sato
  • Use of succinate dehydrogenase inhibitors for controlling ssp
    Patent number: 9232794
    Abstract: The invention relates to the use of succinate dehydrogenase inhibitors, especially of fluopyram, for controlling Sclerotinia ssp., to a method for treating plants or plant parts for controlling Sclerotinia ssp. and to a method for treating seed for controlling Sclerotinia ssp. in the seed and in the plants which grow from the seed, by treating the seed with a succinate dehydrogenase inhibitor.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: January 12, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Ingo Wetcholowsky, Heiko Rieck, Gilbert Labourdette, Jose Augusto Geraldes
  • Electronic autoinjector
    Patent number: D748245
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: January 26, 2016
    Assignees: Bayer Pharma Aktiengesellschaft, Glufsen Medicom A/S, Corporation
    Inventor: Carsten Petersen