Patents Assigned to Bayer
  • Substituted pyridines or pyrimidines, method for their production, agents containing said substances and the use thereof as pesticides
    Publication number: 20060014960
    Abstract: The invention relates to compounds of the formula (I) where the symbols and indices are defined as cited in the description. Said compounds are suitable for controlling pests.
    Type: Application
    Filed: August 14, 2003
    Publication date: January 19, 2006
    Applicant: Bayer CropScience GmbH
    Inventors: Marion Beckmann, Uwe Doller, Gerhard Krautstrunk, Wolfgang Schaper, Daniela Jans, Waltraud Hempel
  • Method for removing deposits from chemical reactors
    Patent number: 6986816
    Abstract: The invention relates to a process for the removal of deposits formed in a reaction apparatus by the precipitation of solids from a liquid reaction mixture, which process is characterized in that particles of a material that is inert under the reaction conditions are introduced into the reaction apparatus, which particles, by suitable mechanical circulation of the reaction mixture, are so moved through the reactor that, during the reaction, by striking the walls or other built-in elements, they abrasively remove precipitates adhered thereto.
    Type: Grant
    Filed: July 8, 2002
    Date of Patent: January 17, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Claus-Peter Reisinger, Sven Michael Hansen, Peter Fischer, Konrad Triebeneck, Joachim Helbig
  • Method for separating methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-6-methyl-1,4-dihydro-5-pyrimidine-carboxylate-recemate
    Patent number: 6987185
    Abstract: The enantiomers of methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-6-methyl)-1,4-dihydro-5-pyrimidinecarboxylate can be separated with the aid of (?)-camphanic acid.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: January 17, 2006
    Assignee: Bayer HealthCare AG
    Inventors: Siegfried Goldmann, Peter Fey
  • Polyadducts containing uretidone groups
    Patent number: 6987158
    Abstract: Polyaddition compounds containing uretdione groups prepared by reacting uretdione polyisocyanates formed from diisocyanates having exclusively secondary- and/or tertiary-attached isocyanate groups with a molar fraction of isocyanurate structures, based on the sum of uretdione groups and isocyanurate groups, of not more than 10%, with compounds reactive towards isocyanates. The polyaddition compounds can be use as a starting component in the preparation of polyurethane plastics, in particular as crosslinkers for heat-crosslinkable powder coating materials. The compounds may be used as starting components in the preparation of moldings and shaped parts, and as starting components in the preparation of coating materials and coatings.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: January 17, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Josef Laas, Reinhard Halpaap, Peter Thometzek, Michael Grahl, Hans-Ulrich Meier-Westhues
  • Process for conditioning standing and flowing water systems
    Patent number: 6986852
    Abstract: The invention relates to a novel conditioning agent based on polysuccinimide, its hydrolysates or its partial hydrolysates, for preventing deposits in standing or flowing water systems.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: January 17, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hermann Sicius, Thomas Sildatke, Thomas Menzel, Wolfgang Wambach, Winfried Joentgen, Thomas Klausa, Thomas Klein
  • Organ, tissue and cell-specific immuno-therapeutic for chronic viral infections and inflammatory, degenerative and proliferative diseases, in particular of the liver, and for cancer, based on a recombinant parapox virus
    Publication number: 20060008471
    Abstract: The present invention relates to the preparation and use of organ-specific, tissue-specific and/or cell-specific recombinant parapoxvirus ovis as a pathogen-specific and organ-specific, targeted immunotherapeutic agent for chronic viral infections and inflammatory, degenerative and proliferative diseases, in particular of the liver, and cancer.
    Type: Application
    Filed: September 13, 2005
    Publication date: January 12, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Olaf Weber, Angela Siegling, Tobias Schlapp
  • Compounds and compositions for the treatment of diabetes and diabetes-related disorders
    Publication number: 20060009483
    Abstract: The present invention relates to novel compounds which are useful in the treatment of diabetes and diabetes-related disorders. The invention also relates to pharmaceutical compositions comprising said compounds, intermediates useful in the preparation of said compounds, and methods of preparation.
    Type: Application
    Filed: May 30, 2003
    Publication date: January 12, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Yamin Wang, Eric Mull
  • Process for preparing aspartates
    Patent number: 6984715
    Abstract: The present invention relates to novel aspartates, their method of production and the use of these mono and polyaspartates as reactive components for polyisocyanates in two-component polyurethane coating compositions and for preparing polyurethane prepolymers.
    Type: Grant
    Filed: October 3, 2003
    Date of Patent: January 10, 2006
    Assignee: Bayer MaterialScience LLC
    Inventors: Richard R. Roesler, Douglas A. Wicks, Terrell Dean Wayt, Brian Long, Karsten Danielmeier, Charles A. Gambino
  • Immunogenic peptides of foot-and-mouth disease viruses
    Patent number: 6984387
    Abstract: The present invention relates to FMDC vaccine based on peptides having a sequence of at least 8 amino acids, which corresponds to a partial sequence of the non-structural protein region of FMDV, which was selected by immunoreactivity with FMDV-specific antibodies or by immunoreactivity with FMDV-specific T lymphocytes, and to their production and their use.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: January 10, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Roberto Correa, Hans-Robert Hehnen, Eberhard Pfaff, Armin Saalmüller, Thomas Pauly, Bettina Höhlich, Bernadette Glatthaar-Saalmüller, Karl-Heinz Wiesmüller
  • Process for the two-step production of dinitrotoluene
    Patent number: 6984762
    Abstract: The invention relates to a process for the production of dinitrotoluene by the two-stage nitration of toluene. In the first stage of this process, toluene was reacted adiabatically with nitrating acid so that at least 90% of the toluene was reacted off and no more than 70% of the toluene formed dinitrotoluene. The resulting organic phase containing mononitrotoluene and the aqueous acid phase containing sulfuric acid were separated, and the aqueous acid phase containing sulfuric acid was concentrated by flash evaporation. The resulting concentrated sulfuric acid was recycled into the reaction in the first stage, and/or into the reaction in the second stage, and/or into the concentration in the second stage. In the second stage, the organic phase containing mononitrotoluene from the first stage was completely reacted isothermally with nitrating acid.
    Type: Grant
    Filed: February 17, 2004
    Date of Patent: January 10, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erwin Dieterich, Anke Hielscher, Berthold Keggenhoff, Manfred Keller-Killewald, Jürgen Münnig, Dietmar Wastian
  • Electrochemical cell for electrolyzers with stand-alone element technology
    Patent number: 6984296
    Abstract: The invention describes an electrochemical cell for the membrane electrolysis process for electrolyzers with single-element technology. The cell consists of at least of 2 half-shells (8, 10), which surround an anolyte chamber (16) and a cathode chamber (22) with a membrane (5) arranged in between, and an anode (6) in the anolyte chamber (16), with the cathode chamber (22) being provided with an oxygen-consuming cathode (4), with a plurality of pressure-compensated gas pockets (15) arranged one above the other, a catholyte gap (14) and optionally a back chamber (19), where electrically conducting supporting elements (7) are provided in the anolyte chamber (16) and supporting elements (3, 2, 1) are provided in the cathode chamber (22) at the same position opposite one another.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: January 10, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventor: Fritz Gestermann
  • Substituted phenylcyclohexane carboxylic acid amides and their use as adenosine uptake inhibitors
    Patent number: 6984642
    Abstract: The present invention relates to substituted phenylcyclohexanecaboxamides of the formula (I), to processes for their preparation and to their use in medicaments, in particular for treating cardiovascular disorders.
    Type: Grant
    Filed: May 16, 2000
    Date of Patent: January 10, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erwin Bischoff, Stephan Lensky, Stephan-Nicholas Müller, Holger Paulsen, Jörg Keldenich, Thomas Krahn, Joachim Schuhmacher, Jan Jänichen, Wolfgang Thielemann, Henning Steinhagen
  • Device for taking measurements of cells which are contained in a liquid environment
    Patent number: 6984297
    Abstract: A method and a device are used for carrying out measurements on cells located in a liquid environment. Each cell is positioned with an underside of its membrane on a surface having a channel running through it. A negative pressure is established to aspirate the cells. Each cell is electrically scanned via at least one electrode which is spaced apart from the cell. The negative pressure is preferably established in a pulse-like manner to rupture the membrane in such a way that the cell interior enclosed by the membrane is connected to the channel.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: January 10, 2006
    Assignees: NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen, Bayer AG
    Inventors: Wilfried Nisch, Martin Stelzle, Alfred Stett, Thomas Krahn, Thomas Müller, Christoph Methfessel
  • Fluorescence-measuring system
    Patent number: 6985225
    Abstract: The invention relates to a fluorescence-measuring system as can be employed for high-throughput screening in drug development. The arrangement for fluorescence excitation contains a two-dimensionally extended sample-receiving device and at least two illumination sources for exciting the fluorescence of the samples. The illumination sources are extended linearly and arranged in such a way that the illuminated area of the sample-receiving device is homogeneously illuminated directly or via deflecting mirrors at an opening angle of ?30°.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: January 10, 2006
    Assignee: Bayer HealthCare Aktiengesellschaft
    Inventors: Martin Bechem, Wolfgang Paffhausen
  • Antiparasitic artemisinin derivatives (endoperoxides)
    Patent number: 6984640
    Abstract: This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substituted deriviatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: January 10, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Richard K. Haynes, William Wai-Lun Lam, Ho-Wai Chan, Hing-Wo Tsang, Man-Ki Cheung, Gisela Greif, Gabriele Schmuck, Arnd Voerste
  • Pyridine derivatives
    Patent number: 6984649
    Abstract: Pyridine compounds of general formula: wherein —R1 represents in which R11 is hydrogen, C1-6 alkyl, halogen, hydroxy, C1-12 alkoxy, nitro, amino, C1-6 alkylsulfonylamino, C1-6 alkoxycarbonyl, C1-6 alkylamino, di (C1-6 alkyl)amino, C1-6 alkanoylamino, phenyl C1-6 alkylamino, phenylsulfonylamino, or —O—(CH2)n—R111; R2 represents hydrogen or halogen; R3 represents 1.2.3.6-tetrahydro-pyridine, or —CR31R32R33 wherein R31 represents H or C1-6 alkyl and R32 and R33 are joined to form a 5-8 membered saturated ring optionally containing up to three heteroatoms; R4 is carbamoyl, CN, carboxyl, etc.; R5 is amino, C1-6 alkylamino, di C1-6 alkylamino, etc. or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological activity.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: January 10, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Toshiki Murata, Masaomi Umeda, Sachiko Sakakibara, Takashi Yoshino, Hiroki Sato, Tsutomu Masuda, Yuji Koriyama, Mitsuyuki Shimada, Takuya Shintani, Hiroshi Kadono, Timothy B. Lowinger, Karl B. Ziegelbauer, Kinji Fuchikami, Hiroshi Komura
  • 5-Nitrobenzofurans
    Patent number: 6984741
    Abstract: The present invention relates to 5-nitrobenzofurans, to a process for preparing 5-nitrobenzofurans, and to 5-nitro-2,3-dihydrobenzofuran-3-ols, to a process for the preparation thereof and to intermediates.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: January 10, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventor: Wolfgang Mägerlein
  • Imidazopyridinones as p38 map kinase inhibitors
    Patent number: 6984646
    Abstract: The invention relates to imidazopyridinones of the formula wherein the groups R1, R2, R3, and R4 are as defined in claim 1, to the process for their preparation, to pharmaceutical compositions containing them, and to a method of using them for treatment of chronic inflammatory processes in humans or animals.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: January 10, 2006
    Assignee: Bayer Healhcare AG
    Inventors: Cristina Alonso-Alija, Martin Michels, Hartmut Schirok, Karl-Heinz Schlemmer, Sara Dodd, Mary Fitzgerald, John Bell, Andrew Gill
  • Peptides acting as both GLP-1 receptor agonists and glucagon receptor antagonists and their pharmacological methods of use
    Publication number: 20060003935
    Abstract: The invention provides polypeptides that act both as an agonist of the GLP-1 receptor and an antagonist of the glucagon receptor. Such polypeptides are useful for treating individuals with type 2 diabetes or other metabolic disorders.
    Type: Application
    Filed: August 26, 2005
    Publication date: January 5, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Clark Pan, James Whelan, Kevin Clairmont
  • Peptides acting as both GLP-1 receptor agonists and glucagon receptor antagonists and their pharmacological methods of use
    Publication number: 20060003419
    Abstract: The invention provides polypeptides that act both as an agonist of the GLP-1 receptor and an antagonist of the glucagon receptor. Such polypeptides are useful for treating individuals with type 2 diabetes or other metabolic disorders.
    Type: Application
    Filed: August 26, 2005
    Publication date: January 5, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Clark Pan, James Whelan, Kevin Clairmont