Patents Assigned to Bayer
  • Publication number: 20170319549
    Abstract: The present invention relates to benzimidazol-2-amines of general formula (I) in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: October 21, 2015
    Publication date: November 9, 2017
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Hartmut REHWINKEL, Sonja ANLAUF, Duy NGUYEN, Olaf PANKNIN, Marcus BAUSER, Katja ZIMMERMANN, Stefan KAULFUSS, Roland NEUHAUS, Paul Matthew BLANEY, Gianna TOSCHI
  • Patent number: 9809542
    Abstract: The invention relates to novel compounds of the formula (I) in which W, X, Y, Z, A and G have the meanings given above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides and/or fungicides. Moreover, the invention relates to selectively herbicidal compositions comprising, firstly, the spiroheterocyclically substituted tetramic acid derivatives and, secondly, a crop plant compatibility-improving compound. The present invention furthermore relates to the boosting of the action of crop protection compositions comprising in particular spiroheterocyclically substituted tetramic acid derivatives through the addition of ammonium or phosphonium salts and optionally penetrants, to the corresponding compositions, to processes for their preparation and to their use in crop protection as insecticides and/or acaricides and/or fungicides and/or for preventing unwanted vegetation.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: November 7, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Reiner Fischer, Arnd Voerste, Isolde Häuser-Hahn, Stefan Lehr, Elmar Gatzweiler, Ulrich Görgens, Ines Heinemann
  • Patent number: 9809792
    Abstract: The invention relates to a separator for retaining and recirculating cells in a continuous-flow or batch-flow type plastic bag or bottle, which can preferably be operated outside of a bioreactor. Additionally, the invention relates to a method for retaining and recirculating cells within or outside a bioreactor. The invention further relates to a method for producing the separator according to the invention.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: November 7, 2017
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Joerg Kauling, Juri Seletzky, Jorgen Magnus, Andre Pastor, Helmut Brod
  • Patent number: 9808571
    Abstract: A pressure sensor for use with a fluid delivery system having good sensitivity at low pressure, but also configured to remain in operating condition after being exposed to high pressures is disclosed herein. In one variation, the pressure sensor includes a fluid path set, a deformable element associated with the fluid path set and configured to deform in response to an external pressure, and a pressure transducer for monitoring deformation of the deformable element. In certain embodiments, the pressure sensor is configured to measure fluid pressure within the range of between about 0 mm Hg to about 300 mm Hg. However, the sensor pressure is also be configured to remain functional after being exposed to pressure in excess of about 60,000 mm Hg.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: November 7, 2017
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Michael A. Riley, Gerald W. Callan, Michael A. Spohn, Michael J. Swantner
  • Publication number: 20170312219
    Abstract: The invention is related to an improved method of contraception, for preventing or suppressing abnormal and/or irregular endometrial bleeding and achieving a rapid induction of amenorrhea by using an intrauterine delivery system comprising controlled release levonorgestrel over a prolonged period of time and at a therapeutic level required for contraception, and a sufficient amount of NSAID capable of suppressing abnormal and/or irregular endometrial bleeding
    Type: Application
    Filed: July 14, 2017
    Publication date: November 2, 2017
    Applicant: Bayer Oy
    Inventors: Bernd Duesterberg, Manja Ahola, Jyrki Pihlaja, Heikki Lyytikäinen, Harri Jukarainen, Satu Kleemola, Tero Parkatti, Tuula Valo, Ina Gröticke, Bernhard Lindenthal, Ulrike Fuhrmann
  • Publication number: 20170313731
    Abstract: The present invention primarily relates to a process for producing methyldichlorophosphane (MDP) by reaction of methane with PCl3 (phosphorus trichloride) in the presence of a catalytically active amount of a compound of formula SOxCl2, wherein the index x may take the value 1 (SOCl2, thionyl chloride) or 2 (SO2Cl2, sulphuryl chloride). The present invention further relates to particular mixtures that are particularly suitable for producing methyldichlorophosphane (MDP) in the context of the process according to the invention/that are formed when carrying out a process according to the invention.
    Type: Application
    Filed: November 18, 2015
    Publication date: November 2, 2017
    Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: HANS-JOACHIM RESSEL, MARK JAMES FORD, Tim HAMMERER, Aurel WOLF
  • Publication number: 20170313700
    Abstract: The present application relates to novel substituted pyrazolo[1,5-a]pyridines and imidazo[1,2-a]pyrazines, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
    Type: Application
    Filed: November 30, 2015
    Publication date: November 2, 2017
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Alexandros VAKALOPOULOS, Damian BROCKSCHNIEDER, Frank WUNDER, Johannes-Peter STASCH, Tobias MARQUARDT, Lisa DIETZ, Volkhart Min-Jian LI
  • Publication number: 20170311602
    Abstract: Provided herein are compositions and methods that are useful for the control of fungal pathogens in crop plants by reducing the incidence of corn stalk, ear and root rots and other diseases and for improving one or more agronomic characteristics of plants. The methods include administration of prothioconazole and/or fluoxastrobin to a plant, a seed, or soil.
    Type: Application
    Filed: November 26, 2014
    Publication date: November 2, 2017
    Applicants: Monsanto Technology LLC, Bayer CropScience LP
    Inventors: Stefan Dutzmann, Frank Kohn, Sally Metz, Jennifer Riggs, Anne Suty-Heinze
  • Patent number: 9801355
    Abstract: The present invention relates to a pesticidal control device that includes at least one pesticidal active ingredient, cellulose fibers, and a polymer or polymer matrix. The combination of the cellulose fibers with the polymer allows for a higher loading of liquid pesticidal active ingredients within the pesticidal control device, maintains the active ingredient within the control device during transportation, storage and handling, and provides higher efficacy or control of pests during treatment. The pesticidal control device may be an ear tag, collar, or bee strip.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: October 31, 2017
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Robert G. Pennington, John Rose, Jochem Rueter
  • Patent number: 9802899
    Abstract: The present application relates to the use of heterocyclic compounds for controlling animal pests including arthropods, insects and nematodes, to novel heterocyclic compounds, to processes for their preparation and to intermediates for preparing the heterocyclic compounds.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: October 31, 2017
    Assignee: BAYER CROPSCIENCE AG
    Inventors: Eike Kevin Heilmann, Joerg Greul, Axel Trautwein, Hans-Georg Schwarz, Isabelle Adelt, Roland Andree, Peter Luemmen, Maike Hink, Martin Adamczewski, Mark Drewes, Angela Becker, Arnd Voerste, Ulrich Goergens, Kerstin Ilg, Johannes-Rudolf Jansen, Daniela Portz
  • Patent number: 9805464
    Abstract: Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generating a suitable patient model used to make such an estimate, to approaches for estimating patient dose by interpolating the results of multiple simulations, and to approaches for a service provider to host a dose estimation service made available to multiple CT scan providers.
    Type: Grant
    Filed: January 19, 2015
    Date of Patent: October 31, 2017
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Gregory Couch, James Couch
  • Patent number: 9801374
    Abstract: The present invention relates to active compound combinations, in particular within a composition, which comprises (A) a N-cyclopropyl-N-[substituted-benzyl]-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide or thiocarboxamide derivative of formula (I) and (B) a further herbicidally active compound or (C) a plant growth regulator and/or (D) a safener for reducing phytotoxic actions of agrochemicals. Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: October 31, 2017
    Assignee: BAYER CROPSCIENCE AG
    Inventors: Pierre Cristau, Peter Dahmen
  • Patent number: 9801387
    Abstract: The present invention relates to a composition comprising at least one biological control agent selected from the group consisting of Bacillus chitinosporus AQ746 (NRRL Accession No. B-21618), Bacillus mycoides AQ726 (NRRL Accession No. B-21664), Bacillus purnilus (NRRL Accession No. B-30087), Bacillus purnilus AQ717 (NRRL Accession No. B-21662), Bacillus sp. AQ175 (ATCC Accession No. 55608), Bacillus sp. AQ177 (ATCC Accession No. 55609), Bacillus sp. AQ178 (ATCC Accession No. 53522), Bacillus subtilis AQ743 (NRRL Accession No. B-21665), Bacillus subtilis AQ713 (NRRL Accession No. B-21661), Bacillus subtilis AQ153 (ATCC Accession No. 55614), Bacillus thuringiensis BD#32 (NRRL Accession No. B-21530), Bacillus thuringiensis AQ52 (NRRL Accession No. B-21619), Muscodor albus 620 (NRRL Accession No. 30547), Muscodor roseus A3-5 (NRRL Accession No. 30548), Rhodococcus globerulus AQ719 (NRRL Accession No. B-21663), Streptomyces galbus (NRRL Accession No. 30232), Streptomyces sp. (NRRL Accession No.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: October 31, 2017
    Assignee: Bayer CropScience AG
    Inventors: Elke Hellwege, Wolfram Andersch, Klaus Stenzel, Bernd Springer
  • Patent number: 9802895
    Abstract: The present invention relates to compounds of the general formula (I), in which R1 to R6, G and n have the meanings given in the description and to a process for their preparation and to their use as insecticides and acaricides.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: October 31, 2017
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Markus Heil, Eike Kevin Heilmann, Werner Hallenbach, Kerstin Ilg, Ulrich Goergens
  • Publication number: 20170305882
    Abstract: Compounds of formula (I) and their use as pharmaceuticals.
    Type: Application
    Filed: September 17, 2015
    Publication date: October 26, 2017
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Anne MENGEL, Hans-Georg LERCHEN, Thomas MÜLLER, Lars BÄRFACKER, Marion HITCHCOCK, Arwed CLEVE, Hans BRIEM, Gerhard SIEMEISTER, Wilhelm BONE, Amaury Ernesto FERNÁNDEZ-MONTÁLVAN, Jens SCHRÖDER, Ursula MÖNNING, Simon HOLTON
  • Publication number: 20170304278
    Abstract: The present application relates to novel heteroaryl-substituted imidazo[1,2-a]pyridines, to processes for preparation thereof, to the use thereof, alone or in combinations, for the treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders.
    Type: Application
    Filed: November 30, 2015
    Publication date: October 26, 2017
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Alexandros VAKALOPOULOS, Damian BROCKSCHNIEDER, Frank WUNDER, Johannes-Peter STASCH, Tobias MARQUARDT, Lisa DIETZ, Volkhart Min-Jian LI
  • Publication number: 20170305912
    Abstract: A process for the preparation of 3-phenyl/heteroaryl-6-phenoxy-8-alkylamino-imidazo[1,2-b]pyridazine derivatives and intermediates of this process. A crystalline form of N-cyclopropyl-4-{6-(2,3-difluor-4-methoxyphenoxy)-8-[(3,3,3-trifluorpropyl)amino]imidazo[1,2-b]pyridazin-3-yl}-2-methylbenzamide. The compounds are inhibitors of the Mps-1 kinase (Monopolar Spindle 1 kinase; also known as Tyrosine Threonine Kinase, TTK).
    Type: Application
    Filed: August 28, 2015
    Publication date: October 26, 2017
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Holger PAULSEN, Uwe MÜNSTER, Nicolas GUIMOND
  • Publication number: 20170303540
    Abstract: The present invention relates to novel triazole derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: September 29, 2015
    Publication date: October 26, 2017
    Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Pierre-Yves COQUERON, Jean-Pierre VORS, David BERNIER, Julie GEIST, Ricarda MILLER, Sven WITTROCK, Ulrike WACHENDORFF-NEUMANN, Stephane BRUNET, Pierre GENIX, Philippe KENNEL
  • Patent number: 9795137
    Abstract: The invention relates to co-crystals of metalaxyl and prothioconazole, to methods of making them, to compositions containing them and to the methods of using said co-crystals and said compositions to treat crops and plants.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: October 24, 2017
    Assignee: Bayer CropScience LP
    Inventor: David Frizzell
  • Patent number: D800562
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: October 24, 2017
    Assignee: Bayer HealthCare LLC
    Inventors: Michael Scott Carpenter, David S. Reynolds, Jr.