Abstract: In order to monitor the administration of medicament portions Ta in a reliable and simple manner, the invention provides a display device for a dispenser for medicament portions Ta, it being necessary to administer the medicament portions at regularly recurring reference administration times, and the display device comprising a display 1 and an electronic actuation means for the display, characterized in that the display comprises a first visualization means 30, 40 for displaying a first period of time between a first reference administration time and the current time, and the first reference administration time being distinguished in that the medicament portion has not been taken by the first reference administration time.
Abstract: The present invention relates to novel compositions and/or formulations, to a process for preparing these compositions and/or formulations and to the use thereof as biologically active compositions and biologically active compositions and/or formulations, especially for the control of phytopathogenic fungi in plants, in the protection of materials and as plant growth regulators.
Abstract: A description is given of a process for preparing 1-indanols and 1-indanamines by palladium-catalyzed arylation and of the use thereof as intermediates for the synthesis of fine chemicals and of active agrochemical ingredients.
Type:
Grant
Filed:
January 23, 2015
Date of Patent:
October 24, 2017
Assignee:
Bayer CropScience Aktiengesellschaft
Inventors:
Mark James Ford, Jean-Pierre Vors, Olivier Baudoin, Simon Janody
Abstract: The present invention relates to a method for increasing the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure, wherein the plants, the plant propagules, the seed of the plants and/or a locus where the plants are growing or are intended to grow are treated with an effective amount of a composition comprising a Bacillus subtilis strain with NRRL Accession No. B-21661, a mutant of the strain having all the identifying characteristics of the strain, or a cell-free extract thereof; and a compound selected from the group consisting of fosetyl, fosetyl-aluminum, propamocarb, and propamocarb hydrochloride; wherein the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure is increased.
Abstract: The disclosure relates to the recombinant Gla domain proteins and their use targeting phosphatidylserine (PtdS) moieties on the surface of cells, particularly those expressing elevated levels of PtdS, such as cells undergoing apoptosis.
Abstract: The present invention relates to novel anthranilamide derivatives of the general formula (I) in which R1, R2, R3, R4, R5, R6, A, Q, Y and n are each as defined in the description—, to the use thereof as insecticides and acaricides for control of animal pests, and to several processes for preparation thereof.
Type:
Grant
Filed:
July 8, 2011
Date of Patent:
October 17, 2017
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Rüdiger Fischer, Ernst Rudolf Gesing, Christoph Grondal, Markus Heil, Heinz-Juergen Wroblowsky, Arnd Voerste, Ulrich Gorgens
Abstract: Techniques are disclosed for estimating patient radiation exposure during computerized tomography (CT) scans. More specifically, embodiments of the invention provide efficient approaches for generating a suitable patient model used to make such an estimate, to approaches for estimating patient dose by interpolating the results of multiple simulations, and to approaches for a service provider to host a dose estimation service made available to multiple CT scan providers.
Abstract: The invention relates to a liquid preparation comprising biologically active fungi and/or fungal organs and/or other microorganisms in a suspension, to a method for producing it and to the use thereof for biological protection of plants, for biological plant strengthening, or for biological soil improvement. Polyether-modified trisiloxane is a preferred liquid used. The preparation according to the invention is notable for easily manageable storage at room temperature, trouble-free transport, and simplicity of production and application.
Abstract: The present invention relates to the use of succinate dehydrogenase inhibitors and/or complex III inhibitors for controlling undesired fungal pathogens and simultaneously improving the ratio of harmful to beneficial microorganisms in crops and to a method for treating crops or parts of crops for controlling undesired fungal pathogens and simultaneously improving the ratio of harmful to beneficial microorganisms by treating the crops or parts of crops with a succinate dehydrogenase inhibitor and/or a complex III inhibitor.
Type:
Grant
Filed:
July 25, 2011
Date of Patent:
October 17, 2017
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Lorianne Fought, Herbert Young, George Musson, Gilbert Labourdette, Dominique Steiger, Heiko Rieck
Abstract: The present invention relates to 5-fluoro pyrimidine derivatives containing a sulfondiimine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
Type:
Grant
Filed:
March 27, 2015
Date of Patent:
October 17, 2017
Assignee:
Bayer Pharma Aktiengesellschaft
Inventors:
Ulrich Lücking, Arne Scholz, Philip Lienau, Gerhard Siemeister, Rolf Bohlmann, Ulf Bömer
Abstract: The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.
Type:
Application
Filed:
September 22, 2015
Publication date:
October 12, 2017
Applicant:
BAYER PHARMA AKTIENGESELLSCHAFT
Inventors:
Susanne RÖHRIG, Eloisa JIMENEZ-NUNEZ, Karl-Heinz SCHLEMMER, Adrian TERSTEEGEN, Henrik TELLER, Alexander HILLISCH, Stefan HEITMEIER, Martina Victoria SCHMIDT, Jens ACKERSTAFF, Jan STAMPFUß
Abstract: The present invention relates to antibodies capable of binding to the coagulation Factor XI and/or its activated form factor XIa and methods of use thereof, particularly methods of use as agents inhibiting platelet aggregation and by this inhibits thrombus formation.
Type:
Grant
Filed:
May 8, 2013
Date of Patent:
October 10, 2017
Assignee:
Bayer Pharma Aktiengesellschaft
Inventors:
Andreas Wilmen, Julia Straβburger, Frank Dittmer, Michael Strerath, Anja Buchmüller, Joanna Grudzinska-Goebel, Ricarda Finnern, Martina Schäfer, Christoph Gerdes, Hannah Jöriβen, Asako Itakura, Philberta Leung, Erik Tucker
Abstract: The present invention relates to a novel crystalline form of 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenylmethansulphonate, to processes for its preparation and to its use in agrochemical preparations.
Type:
Grant
Filed:
October 13, 2014
Date of Patent:
October 10, 2017
Assignee:
BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventors:
Britta Olenik, Stefan Hillebrand, Pierre Wasnaire, Martin Weiss, Ulrike Wachendorff-Neumann
Abstract: The present invention relates to novel heterocyclic compounds, to processes for preparation thereof and to the use thereof for controlling animal pests, which include arthropods and especially insects and acarids.
Type:
Grant
Filed:
July 4, 2014
Date of Patent:
October 10, 2017
Assignee:
BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Inventors:
Bernd Alig, Silvia Cerezo-Galvez, Reiner Fischer, Adeline Köhler, Julia Johanna Hahn, Kerstin Ilg, Peter Lösel, Olga Malsam, Daniela Portz
Abstract: Methods for controlling unwanted vegetation, such as weeds, to turfgrass by applying an active compound combination including a triazolinone herbicide, for example, sulfonylamino-carbonyl-triazolinone, and at least one sulfonylurea herbicides, to turfgrass is described herein. The disclosure also provides for active compound combinations and methods of improving turfgrass quality.
Type:
Grant
Filed:
May 24, 2013
Date of Patent:
October 10, 2017
Assignee:
BAYER CROPSCIENCE LP
Inventors:
Bruce Spesard, Don Myers, Laurence Mudge, Matt Bradley
Abstract: The present invention relates to amino-substituted imidazopyridazine compounds of general formula (I), in which A, R1, R2, R3, R4 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
Type:
Grant
Filed:
November 14, 2013
Date of Patent:
October 10, 2017
Assignee:
BAYER PHARMA AKTIENGESELLSCHAFT
Inventors:
Ludwig Zorn, Knut Eis, Volker Schulze, Detlev Sülzle, Florian Puehler, Philip Lienau, Ulf Bömer, Kirstin Petersen, Andrea Hägebarth
Abstract: Compounds of formula (I) which are inhibitors of Bub 1 kinase, processes for their production and their use as pharmaceuticals.
Type:
Application
Filed:
March 28, 2017
Publication date:
October 5, 2017
Applicant:
Bayer Pharma Aktiengesellschaft
Inventors:
Christoph-Stephan HILGER, Marion HITCHCOCK, Hans BRIEM, Gerhard SIEMEISTER, Amaury Ernesto FERNANDEZ-MONTALVAN, Jens SCHRÖDER, Simon HOLTON, Cornelia PREUßE, Karsten DENNER
Abstract: The present application relates to novel 3-aryl-substituted imidazo[1,2-a]pyridines, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
Type:
Grant
Filed:
June 4, 2014
Date of Patent:
October 3, 2017
Assignee:
BAYER PHARMA AKTIENGESELLSCHAFT
Inventors:
Alexandros Vakalopoulos, Markus Follmann, Ingo Hartung, Philipp Buchgraber, Alexey Gromov, Niels Lindner, Frank Wunder, Johannes-Peter Stasch, Gorden Redlich, Volkhart Min-Jian Li