Abstract: The present invention relates to a method for preparing benzaldehyde oximes of the general formula (I) and to the use thereof as important precursors for the synthesis of agrochemical and pharmaceutical active substances.

Abstract: This present invention relates to a crystalline form of (6S)-5-[4?-Fluoro-2-(trifluoromethyl)biphenyl-4-yl]-6-methyl-3, 6-dihydro-2H-1,3,4-oxadiazin-2-one which is the polymorph C, to processes for its preparation, to pharmaceutical compositions comprising it and to its use in the treatment of disorders.

Abstract: The present invention provides methods for the preparation of Compound (I) intermediate compounds and their use for the preparation of compound (I).

Abstract: The present invention relates to the technical field of the marking of articles by means of optically readable codes and of decoding the codes. Such a code is introduced into a surface of an article. The code is decoded on the basis of a transformed captured image of the code. The transformed captured image is generated from at least one captured image of the code using a machine learning model. The model is trained to generate a transformed captured image from at least one captured image and the readout of the optically readable code leads to less decoding errors than the readout of the code in the at least one captured image. The present invention relates to a method for training the machine learning model and to a method, a system and a computer program product for decoding a code using the trained machine learning model.

Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.

Abstract: The present disclosure relates to the detection of acute respiratory distress syndrome in a patient. Subjects of the present disclosure are a computer system, a method and a computer program product for detection of acute respiratory distress syndrome.

Abstract: The present invention relates to the crystal forms of methyl(2R*,4R*)-4-[[(5S)-3-(3,5-difluorophenyl)-5-vinyl-4H-isoxazole-5-carbonyl]amino]tetrahydrofuran-2-carboxylate (I) existing in the form of two stereoisomers: Methyl(2R,4R)-4-[[(5S)-3-(3,5-difluorophenyl)-5-vinyl-4H-isoxazole-5-carbonyl]-amino]tetrahydrofuran-2-carboxylate of formula (Ia) and methyl (2S,4S)-4-[[(5S)-3-(3,5-difluoro-phenyl)-5-vinyl-4H-isoxazole-5-carbonyl]amino]tetrahydrofuran-2-carboxylate of formula (Ib), to a method for preparing the crystal forms, to the use for preparing stable agrochemical formulations, and to the use in the field of agriculture for controlling harmful plants.

Abstract: The present invention covers combinations comprising one or more inhibitors of DGKalpha and one or more inhibitors of DGKzeta Another aspect of the present invention covers the use of such combinations as described herein for the preparation of a medicament for the treatment or prophylaxis of a disease, particularly of a condition with dysregulated immune responses, particularly cancer, or a viral infection or another disorder associated with aberrant DGKalpha and/or DGKzeta signaling.

Abstract: The invention relates to a spray unit comprising an axle (20), a disc (30), a disc shape modifying assembly (40) and a liquid applicator (50). The disc is configured to spin about the axle centred on the centre of the disc. The liquid applicator is configured to apply liquid to a surface of the disc. The disc shape modifying assembly is configured to modify the trajectory of the liquid droplets that leave the spray unit by way of varying the diameter of the disc.

Abstract: The present invention relates to a novel method for preparing alkyl 4-oxotetrahydrofuran-2-carboxylate (I)

Abstract: The present invention is concerned with the application of biological and/or chemical substances or mixtures of substances, more particularly of crop protection products, and/or nutrients outdoors. Subjects of the present invention are a method, a computer system, an apparatus and a computer program product for dynamically adapting application parameters to variable air movements.

Abstract: The present invention relates to crop protection compounds and to compositions which comprise specific compounds as safeners for reducing phytotoxic effects of agrochemicals, especially herbicides. The invention relates more particularly to certain [5-(phenyl)-5-(heteroaryl)-1H-pyrazol-3-yl)oxy] acetic acid derivatives of the general formula (I) and their salts, to processes for preparing them and to their use as plant protection compounds (safeners).

Abstract: Compounds of formula (I), process for their production and their use as pharmaceuticals.

Abstract: The invention relates to a process for preparing optically active 4-substituted 1,2,3,4-tetrahydroquinolines comprising enantioselective hydrogenation of the corresponding 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium (P,N)-ligand catalyst and an additive.

Abstract: Compounds of formula (I), formula (I), processes for their production and their use as pharmaceuticals.

Abstract: A device for agricultural management includes a processing unit to determine at least one geographical location of an agricultural land area, the determination comprising utilization of a GPS unit. Agricultural data is provided from an input unit to the processing unit. The processing unit determines agricultural management data, the determination comprising utilization of the at least one geographical location and the agricultural data. An output unit outputs agricultural management information to a user of the device on the basis of the agricultural management data.

Abstract: The present disclosure relates to azabicyclyl-substituted heterocyclic compounds of formula (I), wherein A1, A2, m, R3, R4, R5, L, R6, T, the ring Y, p, R7 and Q have the meanings as defined in the specification, to compositions comprising such compounds, to processes and intermediates for their preparation as well as the uses thereof for controlling phytopathogenic microorganisms, such as phytopathogenic fungi.

Abstract: The present invention relates to the technical field of producing artificial contrast-enhanced radiological images by way of machine learning methods.

Abstract: The present invention deals with the selection of antibodies and/or antibody fragments in a selection method. Subjects of the present invention are a method, a system and a computer program product for generating score values for pairs of genes which encode the variable domains of light and heavy chains of antibodies and/or antibody fragments. Antibodies and/or antibody fragments can be selected on the basis of the score values.

Abstract: The present invention relates to crop protection compounds and to compositions which comprise specific compounds as safeners for reducing phytotoxic effects of agrochemicals, especially herbicides. The invention relates more particularly to certain [(1-phenyl-5-(heteroaryl)-1H-1,2,4-triazol-3-yl)oxy]acetic acid derivatives of the general formula (I) and their salts, to processes for preparing them and to their use as crop protection compounds (safeners).