Abstract: Transdermal therapeutic system for administration of moxonidine, containing at least one higher n-alkane-carboxylic acid with at least 12 C atoms as a permeation accelerator.
Type:
Grant
Filed:
August 1, 1988
Date of Patent:
November 21, 1989
Assignee:
Beiersdorf Aktiengesellschaft
Inventors:
Gunter Guse, Michael Horstmann, Axel Erler
Abstract: A device for irrigating the intestines that can be employed during surgery with an irrigating cannula for introducing a rinse and with a drain. To ensure irrigation during surgery of a section of intestine of any diameter upstream of the stenosis while avoiding any contamination of the operating field, the drain consists of an adapter connected germ-proof to a hose and of a plastic fastener securing the intestine to the adapter.
Type:
Grant
Filed:
March 9, 1988
Date of Patent:
October 17, 1989
Assignee:
Beiersdorf Aktiengesellschaft
Inventors:
Albert Heimerl, Hans-Adolf Brammer, Wolfgang Hofeditz
Abstract: New substituted phenoxyalkanolamines and phenoxyalkanol-cycloalkylamines of the general formula I ##STR1## in which R.sup.1 and R.sup.2, which can be identical or different, denote alkyl groups with in each case 1 to 4 carbon atoms, or R.sup.1 and R.sup.2 together denote the group --(CH.sub.2).sub.n --, wherein n is the number 4 or 5, R.sup.3 denotes hydrogen, or an alkyl group or an acyl group with in each case 1 to 6 carbon atoms, R.sub.4 denotes an alkyl group with 1 to 4 carbon atoms or the cyclopropylmethyl group and R.sup.5 denotes hydrogen halogen or alkyl, and acid addition salts thereof, have a cardioselective .beta..sub.1 -adrenolytic and hypotensive action. They can be used as medicaments for the treatment of angina pectoris, hypertension and arrhythmias.
Abstract: An antithrombogenic, non-calcifying, and elastic material on a basis of polyurethane, characterized by the addition of fatty-acid esters and optionally by the further addition of cross-linking agent that react with water.
Abstract: A self-adhesive plaster with glycerol trinitrate in a self-adhesive composition of a saturated rubber and a tackifying resin for transdermal administration is characterized in that the saturated rubber comprises a higher-molecular, structure-forming component and a low-molecular, plasticizing component.
Type:
Grant
Filed:
May 12, 1986
Date of Patent:
October 11, 1988
Assignee:
Beiersdorf Aktiengesellschaft
Inventors:
Gunter Guse, Bodo Asmussen, Johannes Boss, Gunter Borchert
Abstract: Colored, antistatic adhesive tape, characterized in that it comprises(a) a fabric base(b) which is coated with carbon black in a binder,(c) the coating assuming the structure of the fabric base,(d) and printed with a non-conductive thixotropic ink,(e) the ink being present in the recesses of the fabric base, as well as(f) an adhesive on the rear face.
Abstract: Substituted 5-phenylthio-6-aminopyrimidinones of the general formula I ##STR1## in which R denotes an amino or hydroxyl group, and their tautomeric forms and acid addition salts thereof, have diuretic, saluretic and uricosuric actions. They can be used as medicaments for the treatment of hypertension, hyperuricemia and edemas.
Abstract: A blanking strip, made of paper or film, for the partial blanking of objects to be electroplated, such as printed circuit boards, coated with an adhesive composition based on a plastomer, a hard resin and a plasticizer.
Abstract: A heart valve prosthesis with a valve housing in the form of a ring and a curved valve which is mounted within the housing and which is hinged to the valve ring by means of a flat flexible small lug which, if appropriate, is drawn in one region through a slot in the valve ring, is characterized in that the valve and the ring each consist of two rigidly joined halves fitting respectively onto or into each other, and the end portions of the small lug in the form of a short strip are embedded "sandwich"-like between the valve halves on one side and between the ring halves on the other side.
Type:
Grant
Filed:
October 21, 1985
Date of Patent:
February 17, 1987
Assignee:
Beiersdorf Aktiengesellschaft
Inventors:
Hanns Pietsch, Holger Kartheus, Helmut Reul
Abstract: New substituted 1-(4-amino-6,7-dialkoxyquinazolinyl)-4-cyclohexenyl derivatives of piperazine and homopiperazine, of the general formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5, which can be identical or different, denote hydrogen, straight-chain or branched alkyl groups with in each case 1 to 6 carbon atoms, cyclic aliphatic radicals with in each case 5 to 7 carbon atoms, aromatic radicals or substituted aromatic radicals, which can be monosubstituted or polysubstituted by identical or different substituents from the group comprising halogen and lower alkyl groups with in each case 1 to 4 carbon atoms in the alkyl part, or denote aralkyl radicals, furanyl radicals or thienyl radicals, orR.sup.2 and R.sup.3 together denote the group --(CH.sub.2).sub.a --, wherein a is the number 4 or 5, orR.sup.3 and R.sup.4 together denote the group --(CH.sub.2).sub.b --, wherein b is the number 3, 4 or 5,R.sup.6 and R.sup.
Abstract: Substituted phenylpiperazinyl-propanols of the formula I ##STR1## in which R.sup.1 denotes hydrogen or an alkyl group with 1 to 4 carbon atoms and R.sup.2 and R.sup.3, which can be identical or different, each denote hydrogen, halogen, cyano, a trifluoromethyl group, a nitro group, a hydroxyl group, an alkoxy group or an alkyl group with in each case 1 to 4 carbon atoms, it being possible for the alkyl parts in each case to be straight-chain or branched, and their tautomeric forms and their salts as well as acid addition salts and N-oxides, have useful pharmacological properties, in particular a positively inotropic, vasodilating, broncholytic and platelet aggregation-inhibiting action and are therefore suitable for the treatment of cardiac insufficiency, hypertension, asthma and thrombosis.
Abstract: The present invention relates to an oil-cream bath that, added in a conventional amount to the bath water, lends it not only a skin-care and fat-restoration action but also a regenerating and normalizing effect on the skin, especially in the existence of non-clinical deviations from the norm, aging skin for example.
Type:
Grant
Filed:
May 22, 1985
Date of Patent:
December 23, 1986
Assignee:
Beiersdorf Aktiengesellschaft
Inventors:
Walter Engel, Udo Hoppe, Gerhard Sauermann
Abstract: Substituted 5-phenylthio-6-aminopyrimidinones of the general formula I ##STR1## in which R denotes an amino or hydroxyl group, and their tautomeric forms and acid addition salts thereof, have diuretic, saluretic and uricosuric actions. They can be used as medicaments for the treatment of hypertension, hyperuricemia and edemas.
Abstract: Surgical material based on liquid monomeric and pulverulent polymeric acrylates and/or methacrylates, catalysts, accelerators and, if appropriate, customary additives, which passes via a plastic state into the solid state by mixing of the liquid and pulverulent components, and which contains 1-15% by weight, based on the total weight, of one or more non-toxic, liquid aliphatic, saturated mono-, di- or tri-carboxylic acids with 1-6 carbon atoms and, if appropriate, 1 or 2 hydroxyl groups, completely or partially esterified with mono-, di- or tri-hydric alcohols with 1-4 carbon atoms, or liquid ethylene glycols or 1,2- or 1,3-propylene glycols with in each case 2 to about 30 glycol units, these liquids having a boiling point above 100.degree. C., preferably above 150.degree. C.
Abstract: New substituted phenyl-2-(1H)-pyrimidinones of the general formula I ##STR1## in which R.sup.1 denotes an alkyl group having 1 to 4 carbon atoms, and R.sup.2 and R.sup.3, which can be identical or different, each denote hydrogen, halogen, cyano, a trifluoromethyl group, a hydroxyl group or an alkoxy group having 1 to 4 carbon atoms, it being possible for each alkyl moiety to be straight-chain or branched, and their tautomeric forms and their acid addition salts and N-oxides have a positive inotropic effect and can thus be used as medicaments for the treatment of cardiac insufficiency.
Abstract: New substituted tetrahydro-1H-pyrazolo[5,1-a]isoindoles of the formula I ##STR1## in which R.sup.1 denotes a hydrogen or halogen atom or an alkoxy group having 1 to 4 carbon atoms, R.sup.2, R.sup.3 and R.sup.4, which can be identical or different, denote a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, or R.sup.2 and R.sup.3 together denote the ethylene group, and X denotes a nitrogen atom or a methine group, and their acid addition salts have a long-lasting hypertensive effect and can be used as anti-hypotensives.
Abstract: An emulsifier for oil-in-water emulsions consisting essentially of a substantially steroid-free wool-wax alcohol free of .alpha.,.omega.-diols prepared by subjecting(a) wool-wax esters of mono- or multi-valent alcohols of 1 to 6 carbon atoms or(b) wool-wax alcohols optionally containing monovalent aliphatic alcohols of 1 to 6 carbon atoms to catalytic hydrogenation at a pressure of 170 to 300 bars and a temperature of 200.degree. to 300.degree. C. in the presence of a high pressure hydrogenation catalyst to obtain substantially steroid-free wool wax alcohols and removing therefrom .alpha.,.omega.-diols useful as emulsifiers.
Abstract: Dressing material of at least one layer of a polymeric, hydrophilic gel and, where relevant, one or more layers of a carrier material as an intermediate and/or covering layer, wherein the gel consists of 40-50% by weight of a polyvinyl alcohol which is crosslinked and acetalized with formaldehyde and is water-insoluble to the extent of at least 90%, 15-30% by weight of water, 15-45% by weight of one or more polyhydric alcohols with 2-6 C atoms and, where relevant, small amounts of additives and/or auxiliaries.
Type:
Grant
Filed:
June 8, 1983
Date of Patent:
November 12, 1985
Assignee:
Beiersdorf Aktiengesellschaft
Inventors:
Wolfgang Hofeditz, Joachim Hornig, Werner Karmann
Abstract: A gravel-resistant selfadhesive decorative film which consists of(a) a thermoformable base of a calendered EVA-PVC copolymer film 80-900 .mu.m thick, which is(b) coated with a polyurethane primer on which is applied(c) a shearing-resistant, aging-resistant acrylate self-adhesive composition on which is present(d) a covering of release paper or release film.