Abstract: A method for optimizing non-uniform quantization thresholds of an ADC in MLSE-based receivers in an optical communication channel, according to which a Quantized Noise (QN) distortion model, in which the quantization and the channel additive noises are combined is generated. The model is applied on the channel deterministic analog states x(n) and on sequences of analog states and transition probabilities are calculated, which will be used later on to calculate the BER, from channel deterministic states and sequences of channel deterministic states into the discrete ADC quantization regions. Real value outputs of the ADC are replaced by the transition probabilities and non-uniform quantization of the ADC is performed, with thresholds that are optimized for MLSE detection, to obtain maximal statistical separation.

Abstract: The present invention relates to methods for the treatment of hepatic disorders in a subject in need thereof. More specifically, the methods of the invention are based on the administration, preferably, systemic administration, of a therapeutically effective amount of at least one biocompatible alginate biomaterial, any modification thereof and any combination thereof. The invention further provides methods for sustaining serum albumin levels, and/or reducing serum AST and ALT, in subjects suffering from hepatic disorder. Still further, the invention provides methods for reducing apoptosis and inducing cell proliferation in a damaged liver tissue of a subject suffering of hepatic disorder, using the alginate biomaterial described by the invention.

Abstract: Disclosed is a method of compensating for coupling impairments in optical communication systems comprising two or more coupled transmission lines. The method comprises introducing into the system a component comprising an electronic circuit configured to realize at least one of an exact electrical coupling compensation (EECC) algorithm and a spectrally fragmented electrical coupling compensation (SF-ECC) algorithm.

Abstract: The present invention relates to a device and method for transferring rotational, mechanical motion into sinusoidal wave-like motion.

Abstract: A method of monitoring network traffic in a communication network with a sentinel module to detect malicious activity is described. A gateway sentinel module receives network traffic directed through a gateway installed for a local distribution of the network, the gateway connecting the local distribution of the network to a core of the network. Malicious activity in the local distribution is detected based on a combination of: a local machine-learning model for identifying malicious activity in the local distribution, the local machine-learning model modelling network traffic from the local distribution; and a global machine-learning model. The global machine-learning model models network traffic from a plurality of local distributions of the network based training data from a plurality of local sentinel modules executed on a respective plurality of computing nodes. The computing nodes respectively receive network traffic from the plurality of location distributions.

Abstract: The invention relates to a system for protecting a computerized device from activities within the device bootstrap, which comprises: (a) a DC supply monitoring unit for monitoring power consumption of the DC supply of the device during bootstrap; and (b) a database for storing one or more valid bootstrap signatures, each of said valid bootstrap signatures describes a valid variation of power consumption pattern, respectively, from the DC supply of the device; wherein, during bootstrapping of the device, said DC supply monitoring unit continuously monitors the power consumption from said DC supply of the device, compares characteristics of the power consumption with said one or more valid bootstrap signatures in said database, and alerts upon detection of a mismatch.

Abstract: Disclosed herein methods for combating biofouling in a liquid, e.g. an aqueous medium by providing a surface coated with at least one laser-induced graphene (LIG) layer in said liquid medium. Particularly disclosed herein method and devices for treating water comprising passing a water stream through a membrane module equipped with at least one spacer coated with at least one layer of LIG, and optionally by applying an electric potential to the at least one LIG layer to achieve a bactericidal effect in the water stream. Specifically, disclosed herein a polymeric mesh suitable for use as a spacer in a membrane module in water treatment application, said mesh being at least partially coated with LIG.

Abstract: The present invention relates to regulation of ureide levels for optimal plant survival during nutrient remobilization such as occurs during normal growth, dark stress and senescence. Plants can be genetically engineered or selected using a suitable gene marker to have enhanced ureide accumulation. The present invention further provides methods of protecting plants, or extending the shelf life of fresh plant produce by application of exogenous ureides.

Abstract: A system for optimizing power allocation for each optical transmitter in an optical transmission system, the system comprises at least two intensity modulated optical transmitters, each of which is controlled by a modulator; an optical channel that can be spatially multiplexed by a multiplexer; and at least two optical detectors, for detecting the transmitted modulated signals. Each of the modulators are adapted to modulate the transmitters such that the electrical power consumption of the optical transmitters is minimized by a modulation scheme of the modulators, that uses energy efficient convex optimization to multiplex the transmitted optical signals, by the multiplexer in a multiple-input-multiple-output (MIMO) scheme.

Abstract: An isolated peptide is disclosed. The peptide comprises a titanium oxide binding amino acid sequence connected to a heterologous biologically active amino acid sequence via a beta sheet breaker linker, wherein: (i) the titanium oxide binding amino acid sequence is selected to bind coordinatively with titanium oxide; (ii) the titanium oxide binding amino acid sequence is selected to induce a beta sheet structure; and (ii) the titanium oxide binding amino acid sequence binds to titanium oxide with a higher affinity than said biologically active amino acid sequence binds to the titanium oxide under physiological conditions. Use of the peptides and titanium devices comprising same are also disclosed.

Abstract: The invention relates generally to compositions and methods for generating immunotolerant responses in a subject. Specifically, the invention relates to a composition comprising a sulfated polysaccharide and a bioactive polypeptide for generating an immunotolerant response.

Abstract: The caged cell-penetrating peptide (cCPP) conjugates of this invention are ideal for intracellular delivery of a broad variety of cargoes including various nanoparticulate pharmaceutical carriers (liposomes, micelles, microparticles, nanoparticles, polymer-conjugates). The conjugates comprise a detectable agent or a therapeutic agent, and the conjugates provide a novel strategy for site-specific delivery of the same to appropriate tissues in the subject. Versatile application of the conjugates in diagnostics and imaging is described.

Abstract: A linearized MIMO system which includes a MIMO receiver which comprises one or more receiving units, each receiving unit comprises one or more receiving antennas and an optional MIMO spatial decoder. The linearized MIMO system also includes a linearized MIMO transmitter, which comprises a plurality of non-linear power amplifiers at respective transmission branches, where each of the non-linear power amplifiers feeds a respective antenna with an amplified signal. The linearized MIMO system also includes a MIMO spatial pre-coder for receiving an artificial data signal from a global linearizer, and based on a channel state information of the medium (medium-channel), the linearized MIMO system creates a plurality of transmission branch-signals. Each of the branch signals feeds one of the non-linear power amplifiers, respectively. The global linearizer receives a data signal and creates the artificial data signal.

Abstract: A method for obtaining transient Bragg gratings in optical waveguides and several different applications of the transient Bragg gratings obtained using this method are presented. The basic mechanisms for obtaining the transient gratings in the waveguides are refractive index change due to Kerr nonlinearity, free carrier generation, and gratings formed by linear or non-linear absorption of thermal energy. The exemplary applications include an ultra-fast fiber laser source at any central wavelength, a fast spectral switch/modulator, transient pulse stretchers based on transient chirped gratings, Q-switching based on transient gratings, and time reversal of ultra-short pulses and low power sub-nanosecond pulse generations.

Abstract: The invention is an optical system for up-conversion of SWIR images into visible images. The optical system of the invention comprises a liquid crystal optically addressed spatial light modulator (LC-OASLM), which acts as an optical valve, and two optionally GRADIUM lenses to reduce the size and complexity of the optical setup. In embodiments of the invention, the photosensitive layer is replaced by a photodiode or array of photodiodes and the liquid crystal layer is replaced by an array (film) of organic light emitting diodes which emit light at the VIS by collecting SWIR light or by a fluorescence layer with sensitivity in the SWIR range.

Abstract: Provided is a method of treating a pathology associated with neural damage, the method comprising administering non-antigen specific polyclonal activated T cells and/or genetically modified T cells into the brain in a manner which prevents meningoencephalitis in the subject, thereby treating the pathology associated with neural damage. Also provided are devices for intrabrain and intrathecal administration of T cells, which comprise the brain-specific or non-antigen specific polyclonal activated T cells and/or genetically modified T cells and a catheter for intrabrain administration in a manner which prevents meningoencephalitis in a subject.

Abstract: A method of preventing or treating xenotransplant rejection in a subject in need thereof is disclosed. The method comprises administering a therapeutically effective amount of alpha-1-antitrypsin (AAT) in combination with a therapeutically effective amount of an anti-CD8 antibody or an antigen binding fragment thereof.

Abstract: The invention is optical configurations for constructing laser oscillators or laser amplifiers that comprise an extremely short fiber (typically tens of cm long or below, e.g. 5 cm to 30 cm). In order to overcome the absorption limitation due to the very short length of the fiber, the present invention employs a multi pump-pass scheme for pump light confinement. This scheme is based on the small angular overlap between the lasing and pump beams. The multi pump-pass method of the invention leads to efficient fiber laser oscillators and amplifiers having pulse duration of a few ns, with high average and peak power output that is comparable to the state-of-the-art solid state lasers.

Abstract: A spectroscopic method using either tunable or preset non-tunable thin-layered devices or a combination of both to modulate compressed-sensing-compliant, spectral modulations and to use intensity measurements of each respective spectral modulation to numerically reconstruct an estimated spectral distribution of the spectral signal such that the estimated spectral distribution is characterized by a totality of spectral bands exceeding the number of spectral modulations by about one half an order-of-magnitude or more.

Abstract: Disclosed is a device for up-conversion of Short Wavelength Infra-Red (SWIR) images into visible images. The device comprises a sub micrometer thickness structure that is composed of several sub-layers, each having a typical thickness of tens to hundreds of nanometers. The device is composed of two main sections one on top of the other: (a) a highly efficient SWIR absorption thin layer and (b) a highly efficient organic light emitted diode (OLED). The generated visible image is emitted from the OLED through a top transparent cathode, which is deposited on the OLED.