Abstract: Disclosed are a pharmaceutical composition for preventing or treating a respiratory disease, and health functional food, a food composition, and a quasi-drug composition for preventing and ameliorating a respiratory disease, each including, as active ingredients, a Lactobacillus plantarum KC3 strain and a Leonurus japonicus extract. The composition including the Lactobacillus plantarum KC3 strain (Accession No: KCTC13375BP) and the Leonurus japonicus extract as active ingredients according to an aspect has a defense effect against respiratory damage caused by air pollutants such as fine dust and can inhibit expression of IL-17A, TNF-?, and CXCL-1, thereby being able to effectively treat or prevent a respiratory disease including chronic obstructive pulmonary disease (COPD).

Abstract: Provided are a method for producing stem cell-derived extracellular vesicles by using a three-dimensional cell culture process, use of three-dimensional cell aggregates of stem cells in producing extracellular vesicles, a culture of three-dimensional cell aggregates of stem cells comprising a high concentration of extracellular vesicles, and a pharmaceutical composition comprising the culture.

Abstract: The present disclosure relates to a composition for ameliorating immune disorders and preventing or treating respiratory inflammatory diseases, the composition including, as an active ingredient, new lactic acid bacteria from Lactobacillus plantarum KC3 (also referred to as “CKDB-KC3”).

Abstract: The present invention relates to an affinity isolation system and method using a switch-like binding reaction. An affinity isolation system according to an embodiment of the present invention comprises: a ligand (10); a binder (20) to which the ligand (10) is reversibly bound and which structurally changes with the binding reaction thereof with the ligand (10); a recognition material (30) specifically binding to the structurally changed binder (20); an immobilizing member (40) having a surface onto which any one of the binding pair, the binder (20) and the recognition material (30), is immobilized; and a capturing material (50) conjugating with the other of the binding pair, the binder (20) and the recognition material (30), to form a conjugate (C) and specifically binding to the target (1) in a target subpopulation from a sample solution.

Abstract: The present invention relates to a technique in which a target exosome subpopulation, a sub-subpopulation, or a lower population in human fluid, which is associated with a specific disease, is isolated and recovered in its intact form at high yield to prepare a liquid biopsy sample and analyzed.

Abstract: According to an embodiment of the disclosure, a method of creating an object with a conduit is disclosed. A material is deposited on a sacrificial collector; and, the sacrificial collector is then removed to create the object with the conduit. Both the object and the sacrificial collector can approximate the shape of desired blood vessel. The method can also include a 3-D printing of the desired shape of the mold and utilization of Gallium as the sacrificial collector. The sacrificial object is created by insertion of the gallium in the mold. After removal of the gallium from the mold, fibers are electrospun onto the gallium. The gallium is removed through melting—leaving a scaffold, the object with the conduit. In addition to the gallium, an extra sacrificial layer of a water-soluble material may be utilized.

Abstract: The composition may be used therapeutically or prophylactically and is directed toward a cluster of diarrhea-causing pathogens which cause illness or death in animals, including dogs and cats. It is prepared from a powdered egg preparation and powdered protein matrix, such as bovine colostrum. The eggs are collected from hens which have been immunized with the relevant pathogens or toxins. When the matrix includes colostrum, the powdered colostrum is derived from non-hyperimmune cattle. The vaccination strategy includes the use of antibody cross-reactivity between toxins or pathogens which cause diarrhea. For some diseases, including canine parvo, the clinical improvement using this therapeutic exceeds the standard of care. Instead of a pharmaceutical product, this composition is an orally administered food product with the same safety profile as eggs and milk.

Abstract: According to an embodiment of the disclosure, a device with the capability of performing both conventional bioprinting and electrohydrodynamic printing (EHDP) is provided. The disclosure also provides methods of using the described device, methods of optimization of printing parameters, methods of position calibration, methods of selecting or creating voltage waveforms, and other methods relating to the fabrication device.

Abstract: A control device to be connected to a host and a disk device including at least one Redundant Arrays of Independent Disks (RAID) set, the control device includes circuitry that performs data communication with the host by a protocol capable of connecting one logical device in the RAID set to each port, virtually sets a plurality of ports which are defined by the protocol, sets a plurality of logical devices in the RAID set included in the disk device, and connects the plurality of logical devices to the plurality of ports, respectively, and the circuitry is to be connected to the host through an interface.

Abstract: Cryogenic devices are provided in which solid carbon dioxide (dry ice) is used to maintain a temperature zone in which samples can be manipulated under conditions in which the sample is maintained at a temperature below ?50 C.

Abstract: A storage control device that includes processing circuitry that receives second access instructions of a plurality of series generated based on a first access instruction for instructing writing of data in a first storage or reading of data from the first storage, through a plurality of channels, the storage control device being connected to a controller configured to perform writing of data in the first storage or reading of data from the first storage according to an instruction for accessing the first storage, reassembles the first access instruction based on the second access instructions of the plurality of series received by the processing circuitry, and outputs the first access instruction reassembled by the processing circuitry to the controller.

Abstract: A storage controlling system, coupled to a storage apparatus including storage disk devices, receives writing target data, generates a parity in units of parity generation of a given length for the data, and stores the data and parity into the devices. The system includes a cache memory and controller. The controller includes: a reception section receiving a writing instruction including the writing target data and information for specifying a target sector to write the data to; a decision section deciding whether processing target data is held in the cache memory, the processing target data including at least one unit of parity generation that includes sector data stored in the sector and fraction data other than the sector data; and a writing processing section updating, when the processing target data is in the cache memory, the data based on the instruction and outputting the post-update data as the writing target data to the apparatus.

Abstract: A control device to be connected to a host and a disk device including at least one Redundant Arrays of Independent Disks (RAID) set, the control device includes circuitry that performs data communication with the host by a protocol capable of connecting one logical device in the RAID set to each port, virtually sets a plurality of ports which are defined by the protocol, sets a plurality of logical devices in the RAID set included in the disk device, and connects the plurality of logical devices to the plurality of ports, respectively, and the circuitry is to be connected to the host through an interface.

Abstract: A storage control device that includes processing circuitry that receives second access instructions of a plurality of series generated based on a first access instruction for instructing writing of data in a first storage or reading of data from the first storage, through a plurality of channels, the storage control device being connected to a controller configured to perform writing of data in the first storage or reading of data from the first storage according to an instruction for accessing the first storage, reassembles the first access instruction based on the second access instructions of the plurality of series received by the processing circuitry, and outputs the first access instruction reassembled by the processing circuitry to the controller.

Abstract: A storage control device is connected to a disk device that retains write commands including area specifying information specifying areas as write targets and including write object data as write objects and performs writing onto a disk based on the retained write commands. The storage control device includes a controller cache memory in which data read from the disk device is cached, and controller circuitry that generates a write command for writing write object data of a write command received at a second point of time later than a first point of time and gap data between an area specified by area specifying information included in the write command received at the second point of time and an area specified by area specifying information included in the write command received at the first point of time, and outputs the generated write command to the disk device.

Abstract: A storage controlling system, coupled to a storage apparatus including storage disk devices, receives writing target data, generates a parity in units of parity generation of a given length for the data, and stores the data and parity into the devices. The system includes a cache memory and controller. The controller includes: a reception section receiving a writing instruction including the writing target data and information for specifying a target sector to write the data to; a decision section deciding whether processing target data is held in the cache memory, the processing target data including at least one unit of parity generation that includes sector data stored in the sector and fraction data other than the sector data; and a writing processing section updating, when the processing target data is in the cache memory, the data based on the instruction and outputting the post-update data as the writing target data to the apparatus.

Abstract: Embodiments of this invention encompass a method for producing and purifying rebaudioside C. In particular, this invention relates to a method for purifying rebaudioside C compositions to obtain a substantially pure rebaudioside C product using one or more crystallization steps. Resulting polymorphic forms of rebaudioside C, substantially pure rebaudioside C compositions and their uses are disclosed.

Abstract: A method is provided for reducing weight in a subject by administering an effective amount of a composition comprising omega-3 polyunsaturated fatty acid (PUFA), at least one of L-arginine, L-ornithine, an L-arginine precursor and an L-ornithine precursor, and at least one of a nucleobase, a nucleoside and a nucleic acid. The method can also be used to treat obesity, hyperlipidemia, diabetes and/or hypertension and for improving diathesis, or treating adult disease or disposition to adult disease.

Abstract: The present invention is directed to the use of rebaudioside C, or a stereoisomer thereof, for enhancing the sweet taste of carbohydrate sweeteners, such as sucrose and fructose. The present invention is also directed to consumables comprising a combination of a carbohydrate sweetener and rebaudioside C, or a stereoisomer thereof.

Abstract: The present invention is directed to the use of rebaudioside C, or a stereoisomer thereof, for enhancing the sweet taste of carbohydrate sweeteners, such as sucrose and fructose. The present invention is also directed to consumables comprising a combination of a carbohydrate sweetener and rebaudioside C, or a stereoisomer thereof.