Patents Assigned to Board of Trustees of the University
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Publication number: 20230414305Abstract: A robotic surgical station is disclosed having a wheeled base, a partial-ring shaped structure slidably coupled to the based to be rotatable relative to the base about a horizontal roll axis passing through a center of the ring shape, a patient's bed restrained to a first arcuate segment of the partial-ring shaped structure at a first mount, a plurality of robotic arms restrained to a second arcuate segment of the partial-ring shaped structure at a second mount, and a remote control unit to command one or more of the plurality of robotic arms. The second arcuate segment is rotatable sideways with respect to the first arcuate segment to allow full access to the patient's bed by a surgeon.Type: ApplicationFiled: November 9, 2021Publication date: December 28, 2023Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Pier Cristoforo GIULIANOTTI, Andreas VOGLER
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Patent number: 11850256Abstract: Provided herein are complexes comprising amphotericin B (AmB) or derivatives and sterols. Also provided herein are methods of treating cystic fibrosis using AmB or complexes comprising AmB or derivatives and sterols.Type: GrantFiled: June 1, 2021Date of Patent: December 26, 2023Assignee: The Board of Trustees of the University of IllinoisInventors: Martin D. Burke, Katrina A. Muraglia
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Patent number: 11853719Abstract: An exemplary random number generation system leverages the r includes at least one solar power panel of a solar power system, at least one sensor and a random number generator. The sensor senses one or more output parameters (e.g., voltage or current) from the solar power system and provides the sensed parameter to the random number generator, which uses the sensed parameter to generate a number that is truly random (i.e., is not deterministic). As an example, the random number generator may receive multiple samples of the measured parameter and generate a random number based on a difference of the multiple samples. If desired, the random number generator may include an algorithm to remove biasing in the random number.Type: GrantFiled: May 3, 2019Date of Patent: December 26, 2023Assignee: Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in HuntsvilleInventor: Biswajit Ray
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Patent number: 11855529Abstract: The invention discloses a novel control scheme/strategy for the stacked structure LLC resonant converter. The control scheme includes a control signal as a gating signal of the fourth switch, and gating signals of the first, second and third switches that are operably generated according to the gating signal of the fourth switch. The gating signals of the second switch has a same duty ratio as and a phase shift of 180 degrees from the gating signal of the fourth switch. The gate signals of the first and third switches are complementary with the gate signals of the second and fourth switches, respectively. By adopting the control strategy, a three level LLC resonant network input voltage is generated, which includes Vin, Vin/2 and 0.Type: GrantFiled: September 13, 2021Date of Patent: December 26, 2023Assignee: BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSASInventors: Homer Alan Mantooth, Yuqi Wei
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Publication number: 20230408926Abstract: Plasma-Activated liquids and methods of using the same are described. In one aspect, a method of manufacturing an integrated circuit includes activating a photolithography liquid with a plasma; and treating a device component with the activated photolithography liquid. In one example, the photolithography liquid is a photoresist. Activating the photoresist liquid may impart reactive species to the photoresist.Type: ApplicationFiled: November 8, 2021Publication date: December 21, 2023Applicant: The Board of Trustees of the University of IllinoisInventors: David RUZIC, Mohan SANKARAN, Christian WILLIAMS
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Patent number: 11845038Abstract: Methods of reducing acid gas from a stream, comprising contacting the stream with a solvent system comprising a glycerol derivative are described herein. Disclosed herein is a composition comprising a glycerol derivative and an acid gas. A method for sweetening a natural gas stream comprising contacting a solvent system comprising a glycerol derivative with a natural gas stream is described herein.Type: GrantFiled: August 18, 2022Date of Patent: December 19, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMAInventors: Jason E. Bara, Brian Flowers, Max Mittenthal
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Patent number: 11845660Abstract: Chemical looping reform methods comprising heating an oxygen carrier in the presence of a catalyst and plasma radicals to react the oxygen carrier with a fuel to provide a reduced oxygen carrier; and contacting the reduced oxygen carrier with water or carbon dioxide to produce hydrogen or carbon monoxide, respectively, and regenerate the oxygen carrier. The chemical looping reform methods are carried out at low temperatures such as from 150° C. to 1000° C., preferably from 150° C. to 500° C. Catalyst used in the chemical looping reform methods include a sintered rare earth metal oxide oxygen carrier and perovskite. Methods of preparing the catalyst are also provided.Type: GrantFiled: December 9, 2019Date of Patent: December 19, 2023Assignee: The Board of Trustees of The University of AlabamaInventors: Mruthunjaya Uddi, Rajagopalan Varadarajan Ranganathan, Steven M. Fondriest
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Patent number: 11845084Abstract: Provided are methods and related devices for preparing a cell and tissue culture, including a hanging drop culture. Microwells are specially loaded with cell mixtures using a removable reservoir and forcing cells into the underlying microwells. The removable reservoir is removed and the cells partitioned into the individual microwells and covered by an immiscible layer of fluid. The microwells and immiscible layer is inverted and the cells in the microwells cultured. The microwells may have shape-controlling elements to control the three-dimensional shape of the culture.Type: GrantFiled: May 4, 2021Date of Patent: December 19, 2023Assignees: The Board of Trustees of the University of Illinois, Mayo Foundation for Medical Education and ResearchInventors: Anurup Ganguli, Rashid Bashir, Panagiotis Z. Anastasiadis, George Vasmatzis
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Patent number: 11845543Abstract: Systems and methods for enabling infinite wireless charging of unmanned aerial systems (UASs) are provided. A UAS detects sources of power and wirelessly charges itself by collecting ambient electromagnetic energy from a power infrastructure. A UAS in accordance with features and aspects described herein is autonomous, may always be wirelessly charged (e.g., with high induced voltage), and can make use of weak energy. Moreover, various charging techniques can be used, such as in-flight, trickle, perching, and/or parking. Dynamic flight is supported using multi-angle MIMO coils. Additionally or alternatively, faster charging can be achieved with a supercapacitor and slower charging can be achieved with a battery.Type: GrantFiled: December 17, 2020Date of Patent: December 19, 2023Assignee: The Board of Trustees of The University of AlabamaInventor: Nathan Seongheon Jeong
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Patent number: 11844798Abstract: The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.Type: GrantFiled: December 22, 2020Date of Patent: December 19, 2023Assignees: The Board of Trustees of the University of Illinois, Vanquish Oncology, Inc., The Johns Hopkins UniversityInventors: Paul J. Hergenrother, Rachel C. Botham, Timothy M. Fan, Mark J. Gilbert, Michael K. Handley, Avadhut Joshi, Gregory J. Riggins, Theodore M. Tarasow
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Publication number: 20230397945Abstract: The disclosure provides an example electrosurgical system and methods for use thereof. The electrosurgical system includes a high-frequency inverter (“HFI”) having a full bridge and a control system electrically coupled to the HFI. The control system controls output parameters including one or more of an output power Pout(t) and an output voltage or current by varying power reference Pref(t) or switch states of the HFI. The control system causes a power adaptation ?P(t) to a preset power set Pset based on receiving at least one of impedance feedback and thermal feedback according to the following relationship: Pref(t)=Pset+?P(t).Type: ApplicationFiled: June 14, 2023Publication date: December 14, 2023Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Sudip Mazumder, Congbo Bao
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Patent number: 11841307Abstract: Microfabricated PM sensors measure concentrations of particulate matter (PM) in air. Some sensors improve the accuracy of measurements by accounting for the effect of ambient conditions (e.g., temperature or humidity) on mass-sensitive elements employed to determine a mass of the PM in a stream of air. Some sensors improve the accuracy of measurements by controlling humidity in the stream of air measured by mass-sensitive elements. Some sensors employ a plurality of mass-sensitive elements to extend the useful life of the PM sensor. Some sensors employ one or more mass-sensitive elements and heating elements to cause deposition and allow measurement of different sizes of PM. Some sensors can measure mass concentration of coarse PM in addition to fine PM in a stream of air. Some sensors control the flow rate of a stream of air measured by mass-sensitive elements. Some sensors include features to mitigate electromagnetic interference or electromagnetic signal loss.Type: GrantFiled: November 9, 2017Date of Patent: December 12, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventor: Igor Paprotny
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Patent number: 11840533Abstract: Described herein are pyridinone-based compounds, derivatives thereof, and pharmaceutical formulations thereof. In some aspects, the pyridinone-based compounds, derivatives thereof, and/or pharmaceutical formulations thereof can be administered to a subject in need thereof. In some aspects, pyridinone-based compounds, derivatives thereof, and/or pharmaceutical formulations thereof can modulate an activity and/or a function of a BRD protein and/or BET protein.Type: GrantFiled: May 16, 2022Date of Patent: December 12, 2023Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Gregory R. Thatcher, Rui Xiong, Jiong Zhao, Yangfeng Li
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Publication number: 20230391721Abstract: Small molecule ER? biomodulators that kill therapy-resistant ERa positive breast, ovarian, and endometrial cancer cells are disclosed. In one embodiment, the small molecule biomodulator has increased therapeutic utility because of an increased ability to kill therapy-resistant cancer cells compared to BHPI and other conventional therapies (endocrine therapies, tamoxifen, and fulvestrant/ICI). The small molecule biomodulators not only inhibit proliferation of the cancer cells but kills them, which prevents reactivation of tumors years later. Compounds of the invention, such as ErSO-DFP, are effective for treating ERa positive cancers such as breast cancer, ovarian cancer, uterine cancer, cervical carcinoma, endometrial cancer, and the like.Type: ApplicationFiled: October 21, 2021Publication date: December 7, 2023Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: Paul J. HERGENROTHER, Matthew BOUDREAU
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Patent number: 11833147Abstract: The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.Type: GrantFiled: January 8, 2021Date of Patent: December 5, 2023Assignees: Vanquish Oncology, Inc., The Board of Trustees of the University of IllinoisInventors: Paul J. Hergenrother, Rachel C. Botham, Timothy M. Fan, Mark J. Gilbert, Michael K. Handley, Howard S. Roth, Theodore M. Tarasow
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Patent number: 11836852Abstract: A method includes receiving data including a plurality of data items, each data item of the plurality of data items including a three-dimensional (3D) radar heat map of an object and a corresponding two-dimensional (2D) image of the object captured by a stereo camera, inputting the training dataset into a machine learning model including a neural network (NN) that generates, from the 3D radar heat map, a 2D depth map for the object and outputs a probability that the 2D depth map is the corresponding 2D image of the object, and training the machine learning model based on a training dataset to generate a trained machine learning model that iteratively learns to generate an updated 2D depth map that approximates the corresponding 2D image. The training dataset includes the plurality of data items, the 2D depth map and the probability.Type: GrantFiled: December 17, 2020Date of Patent: December 5, 2023Assignee: Board of Trustees of the University of IllinoisInventors: Junfeng Guan, Seyedsohrab Madani, Suraj S. Jog, Haitham Al Hassanieh, Saurabh Gupta
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Patent number: 11833493Abstract: A method for C—H bond activation and/or C—N coupling reaction comprises adding a hydrocarbon material to a container; adding a metal catalyst to the container; adding a primary or a secondary amine to the container. The metal catalyst is represented by the following formula: where Q is a 5 or 6 membered aromatic ring; W, X, and Y are the same or different, and are independently N, S, P, or O; M is Ni, Pd, Fe, Co, Cr, Mn, Cu, Pt, Ir, or Ru; Z is halide (F, Cl, Br, or I); R1 and R2 are the same or different, and are independently alkyl, aryl, alkylaryl or cycloalkyl; and n is 1, 2, or 3.Type: GrantFiled: June 6, 2022Date of Patent: December 5, 2023Assignee: BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSASInventors: Anindya Ghosh, Andrew L. Brandt, Charlette Parnell
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Patent number: 11832948Abstract: The provided systems, methods and devices describe lightweight, wireless tissue monitoring devices that are capable of establishing conformal contact due to the flexibility or bendability of the device. The described systems and devices are useful, for example, for skin-mounted intraoperative monitoring of nerve-muscle activity. The present systems and methods are versatile and may be used for a variety of tissues (e.g. skin, organs, muscles, nerves, etc.) to measure a variety of different parameters (e.g. electric signals, electric potentials, electromyography, movement, vibration, acoustic signals, response to various stimuli, etc.).Type: GrantFiled: December 21, 2021Date of Patent: December 5, 2023Assignees: NORTHWESTERN UNIVERSITY, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISInventors: John A. Rogers, Michel Kliot, Roozbeh Ghaffari, YuHao Liu
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Patent number: 11833386Abstract: Various implementations include a spotting device for supporting a barbell, the spotting device including a base and an arm. The base has a base body with first end and a second end, at least one foot coupled to the second end of the base body, and a base longitudinal axis. The arm has an arm body with a first end and a second end, a coupler coupled to the first end of the arm body, and an arm longitudinal axis. The coupler is couplable to a portion of a barbell. One of the first end of the base body and the second end of the arm body defines a body opening extending partially through the one of the base body or the arm body, and the other of the second end of the arm body and the first end of the base body is slidably disposed within the body opening.Type: GrantFiled: January 12, 2022Date of Patent: December 5, 2023Assignee: The Board of Trustees of The University of AlabamaInventors: Michael R. Esco, Will Wright
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Patent number: PP35552Abstract: Description and specifications of a new and distinct cultivar of blackberry plant named ‘APF-409T’ which originated from seed produced by a hand-pollinated cross of Arkansas selections ‘A-2504T’ (an unpatented breeding selection) x ‘APF-295T’ (an unpatented breeding selection) is provided. This new cultivar of blackberry plant can be distinguished by its excellent plant health, thornless canes, strong primocane-fruiting tendency, and early season of fruit ripening on both floricanes and primocanes.Type: GrantFiled: April 14, 2023Date of Patent: December 19, 2023Assignee: The Board of Trustees of The University of ArkansasInventor: John R. Clark