Patents Assigned to Board of
  • Method and system for computing and integrating genetic and environmental health risks for a personal genome
    Patent number: 8700337
    Abstract: Methods and systems are provided for the computation and display of an individual's personalized health risk based on the genome sequence of the individual, known etiological interactions between diseases for which the individual is determined to have genetic risk factors, and environmental etiological factors associated with the same diseases that represent potentially modifiable disease risk modifiers.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: April 15, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Joel T. Dudley, Atul J. Butte, Alexander A. Morgan
  • Peptide inhibition of lung epithelial apoptosis and pulmonary fibrosis
    Patent number: 8697840
    Abstract: During lung injury, p53 expression increases, inducing plasminogen activator inhibitor-1 (PAI-1) while inhibiting expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR), resulting in apoptosis of lung epithelial cells (LECs). In the bleomycin lung injury model, p53 and PAI-1 are induced while uPA and uPAR are inhibited. A 20 residue peptide DGIWKASFTTFTVTKYWFYR termed PP-1 (the Cav-1 scaffolding domain) or peptide NYHYLESSMTALYTLGH, termed PP-2, protected LECs from bleomycin-induced apoptosis in vitro and in vivo and prevented subsequent pulmonary fibrosis by attenuating lung epitheilial damage. Pharmaceutical compositions, peptide multimers and deliverable polypeptides comprising the above peptides are dislcosed.
    Type: Grant
    Filed: March 5, 2009
    Date of Patent: April 15, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventors: Sreerama Shetty, Steven Idell
  • SOLID CARRIER SPRAYER APPARATUS AND METHODS OF USING SAME
    Publication number: 20140097264
    Abstract: A solid carrier sprayer apparatus, including a solid carrier container, a liquid container, a solid carrier spreading apparatus, and a liquid application apparatus is provided. The solid carrier spreading apparatus can be coupled to receive solid carrier from the solid carrier container, and is configured to drop the received solid carrier substantially evenly over an area of ground. The liquid application apparatus can be coupled to receive liquid from the liquid container, and is configured to spray received liquid substantially evenly over the received solid carrier, such that the liquid is sprayed substantially evenly over the received solid carrier before the solid carrier is dropped substantially evenly over the area of ground. Methods of using a solid carrier sprayer apparatus are also discussed.
    Type: Application
    Filed: December 10, 2013
    Publication date: April 10, 2014
    Applicant: Board of Trustees of Michigan State University
    Inventors: A. Ronald Detweiler, Gary Zehr, Joseph Vargas
  • TREATMENT OF CARDIOVASCULAR DISORDERS WITH TARGETED NANOPARTICLES
    Publication number: 20140100411
    Abstract: Methods for treating various cardiovascular disorders include targeted delivery of calcium ions for permanently impairing a portion of the autonomic nervous system (ANS). Targeted delivery may be via magnetically-targetable nanoparticles.
    Type: Application
    Filed: December 12, 2013
    Publication date: April 10, 2014
    Applicant: The Board of Regents of the University of Oklahoma
    Inventor: Sunny Po
  • HERV-K ANTIGENS, ANTIBODIES, AND METHODS
    Publication number: 20140099324
    Abstract: Methods and compositions for cancer diagnostics and therapy are provided. More particular, methods and compositions for detecting, preventing, and treating HERV-K+ cancers are provided. One example of a method may involve a method for preventing or inhibiting cancer cell proliferation by administering to a subject a cancer cell proliferation blocking or reducing amount of a HERV-K env protein binding antibody.
    Type: Application
    Filed: March 18, 2013
    Publication date: April 10, 2014
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventor: Feng WANG-JOHANNING
  • SALT-TOLERANT ANIONIC SURFACTANT COMPOSITIONS FOR ENHANCED OIL RECOVERY (EOR) APPLICATIONS
    Publication number: 20140096967
    Abstract: The present invention includes compositions and methods for using an anionic surfactant composition for treating a hydrocarbon-bearing formation or a reservoir, of formula (I): wherein R1 and R2 are identical or different and may independently be alkyl, alkenyl, alkynyl, alkylene, aryl, propylene oxide, ethylene oxide or hydrogen groups in a straight or branched chain with 16 or more carbon atoms, X1 and X2 are identical or different and are selected from the group consisting of phosphate, sulfate, carboxylate, sulfonate or other suitable anionic groups, S is a spacer group selected from short or long arkyl, alkenyl, alkynyl, alkylene, stilbene, polyethers, and other suitable aliphatic or aromatic groups comprising 2 to 12 carbon atoms.
    Type: Application
    Filed: August 9, 2013
    Publication date: April 10, 2014
    Applicant: Board of Regents, The University of Texas System
    Inventors: Mukul M. Sharma, Bo Gao
  • SMART GAIT REHABILITATION SYSTEM FOR AUTOMATED DIAGNOSIS AND THERAPY OF NEUROLOGIC IMPAIRMENT
    Publication number: 20140100494
    Abstract: The present invention describes a Smart Gait Rehabilitation System (SGRS). The present invention is capable of performing a quantitative analysis of human movements based on the simultaneous measurement of within-subject stride-to-stride changes in gait using accelerometers, gyroscopes, goniometers, and electromyography (EMG). The system described in the present invention is based on step-training that incorporates sensory feedback, provide feedback about kinematics and torques, and proceeds at walking speeds typical of overground ambulation.
    Type: Application
    Filed: December 16, 2013
    Publication date: April 10, 2014
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Thompson Sarkodie-Gyan, Adrian Trejo
  • FORMATE-ASSISTED PYROLYSIS
    Publication number: 20140100396
    Abstract: The present invention provides, among other thing, methods for creating significantly deoxygenated bio-oils form biomass including the steps of providing a feedstock, associating the feedstock with an alkali formate to form a treated feedstock, dewatering the treated feedstock, heating the dewatered treated feedstock to form a vapor product, and condensing the vapor product to form a pyrolysis oil, wherein the pyrolysis oil contains less than 30% oxygen by weight.
    Type: Application
    Filed: January 4, 2013
    Publication date: April 10, 2014
    Applicant: UNIVERSITY OF MAINE SYSTEM BOARD OF TRUSTEES
    Inventors: William Joseph DeSisto, Marshall Clayton Wheeler, Adriaan R.P. van Heiningen
  • RADIOACTIVE LUMINESCENT NANOPARTICLE COMPOSITIONS
    Publication number: 20140099256
    Abstract: An embodiment of the invention is directed to a composition comprising a luminescent noble metal nanoparticle, wherein the surface of the noble metal nanoparticle is coated with a ligand, and wherein the noble metal nanoparticle is about 2 nm to 5 nm in diameter and further wherein a portion of the noble metal is present as its radioactive isotope. In an embodiment of the invention, the radioactive isotope is present at a concentration of up to 2% w/w of the noble metal.
    Type: Application
    Filed: August 28, 2013
    Publication date: April 10, 2014
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Jie Zheng, Xiankai Sun
  • TREATMENT METHODS USING VERY LONG CHAIN POLYUNSATURATED FATTY ACIDS
    Publication number: 20140100280
    Abstract: Compositions that include Very Long Chain Polyunsaturated Fatty Acids (VLC-PUFAs) are disclosed, along with methods of production and use thereof.
    Type: Application
    Filed: November 8, 2013
    Publication date: April 10, 2014
    Applicant: THE BOARD REGENTS OF THE UNIVERSITY OF OKLAHOMA
    Inventors: Robert E. Anderson, Martin-Paul Agbaga, Richard S. Brush
  • SOYBEAN BASED FIBERS
    Publication number: 20140100351
    Abstract: Fibers can be formed from monomers derived from a biorenewable source. In an embodiment, a fiber forming composition that includes a monomer or mixture of monomers with at least one monomer being derived from a biorenewable source in placed in a fiber producing device. At least a portion of the fiber forming composition is ejected through an opening of the fiber forming device. The ejected fiber forming composition is subjected to light at wavelengths sufficient to activate a reaction which causes solidification of the fiber as the fibers are ejected from the fiber producing device.
    Type: Application
    Filed: August 28, 2013
    Publication date: April 10, 2014
    Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Christopher J. Ellison, Dustin W. Janes
  • ENZYME INHIBITING COMPOUNDS AND METHODS
    Publication number: 20140100198
    Abstract: The invention provides compounds, compositions, and methods for studying the Rohmer pathway and for treating bacterial infections or parasitic infections. The parasitic infection can be a protozoan infection, such as malaria. The compounds and compositions can also be used as antibiotics, for example, to kill bacteria or parasites, or to inhibit bacterial or parasite growth. The invention further provides inhibitors of isoprenoid biosynthesis enzymes, and methods of inhibiting the activity of isoprenoid biosynthesis enzymes. The compounds can be, for example, alkynes or allenes that bind to a unique Fe of an Fe4S4 cluster of an isoprenoid biosynthesis enzyme.
    Type: Application
    Filed: December 12, 2013
    Publication date: April 10, 2014
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Eric Oldfield, Ke Wang, Weixue Wang, Yonghui Zhang
  • POLARIZATION-SENSITIVE SPECTRAL INTERFEROMETRY
    Publication number: 20140098373
    Abstract: A polarization sensitive spectral interferometer apparatus and method for analyzing a sample by optical energy reflected from the sample. The polarization sensitive spectral interferometer apparatus and method determines polarization properties of the sample by optical energy reflected from the sample.
    Type: Application
    Filed: September 30, 2013
    Publication date: April 10, 2014
    Applicant: Board of Regents, The University of Texas System
    Inventors: Thomas E. Milner, Nathaniel J. Kemp, Eunha Kim
  • MOLECULAR FAN
    Publication number: 20140096942
    Abstract: A molecular fan for dissipating heat, the fan having a chemically functionalized molecular fan thin film coating affixed to a surface in need of heat dissipation. A nanocoating for dissipating heat, the coating having a thin film coating affixed to a surface in need of heat dissipation. A molecular fan thin film coating affixed to a surface in need of heat dissipation for dissipating heat.
    Type: Application
    Filed: September 30, 2013
    Publication date: April 10, 2014
    Applicant: BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY
    Inventor: Chhiu-Tsu Lin
  • Female specific insect expression system
    Patent number: 8691564
    Abstract: The present invention provides an insect expression system that may be used to provide biological control of pest insects and control transmission of infectious diseases transmitted to the human population by insects.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: April 8, 2014
    Assignee: The Board of Trustees of the University of Arkansas
    Inventor: Helen Benes
  • Neuromorphic spatiotemporal where-what machines
    Patent number: 8694449
    Abstract: In various embodiments, electronic apparatus, systems, and methods include a unified compact spatiotemporal method that provides a process for machines to deal with space and time and to deal with sensors and effectors. Additional apparatus, systems, and methods are disclosed.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: April 8, 2014
    Assignee: Board of Trustees of Michigan State University
    Inventors: Juyang Weng, Zhengping Ji, Matthew Luciw, Mojtaba Solgi
  • Soybean gene for resistance to alphis glycines
    Patent number: 8692053
    Abstract: An Aphis glycines resistance Rag2 gene is provided herein, along with methods for identifying its presence using marker-assisted selection. A cultivar of G. max having resistance to Aphis glycines conferred by the Rag2 gene has been identified. The Rag2 gene, as well as the methods, aphid-resistant varieties, and markers disclosed herein may be used to breed new elite lines expressing soybean aphid resistance.
    Type: Grant
    Filed: January 12, 2011
    Date of Patent: April 8, 2014
    Assignees: The Board of Trustees of the University of Illinois, The United States of America, as represented by the Secretary of Agriculture
    Inventors: Curtis B. Hill, Glen L. Hartman
  • Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby
    Patent number: 8691780
    Abstract: Methods and compositions for enhancing taxane sensitivity are provided. Aspects of the subject methods include administering to a subject a txr1 pathway modulatory agent in conjunction with a taxane. Also provided are txr1 polypeptides and nucleic acids encoding the same. The subject methods and compositions find use in a variety of different applications.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: April 8, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Chih Jian Lih, Stanley N. Cohen
  • Methods and systems for fluid examination and remediation
    Patent number: 8691582
    Abstract: A method for in situ monitoring within a specified environment. The method includes locating a housing in a well, wherein a set of pumps and a plurality of test beds are inserted. Each of the set of pumps are controlled by signals from the control system to push water from each pump into one of the plurality of separate test beds where, after flowing through each of the test beds, effluent flows into an effluent storage device.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: April 8, 2014
    Assignee: Arizona Board of Regents
    Inventor: Rolf U. Halden
  • Method and apparatus for congestion-aware routing in a computer interconnection network
    Patent number: 8694704
    Abstract: The present disclosure relates to an example of a method for a first router to adaptively determine status within a network. The network may include the first router, a second router and a third router. The method for the first router may comprise determining status information regarding the second router located in the network, and transmitting the status information to the third router located in the network. The second router and the third router may be indirectly coupled to one another.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: April 8, 2014
    Assignee: Board of Regents, University of Texas Systems
    Inventors: Paul Gratz, Boris Grot, Steven W. Keckler