Abstract: A single-walled carbon nanotube-based planar photodetector includes a substrate; a first electrode and a second electrode disposed on the substrate and spaced apart from each other; a plurality of single-walled carbon nanotubes, each of the plurality of single-walled carbon nanotubes contacting the first electrode and the second electrode; and an adsorbent attached to a surface of at least one of the plurality of single-walled carbon nanotubes, wherein the adsorbent is capable of doping the at least one of the plurality of single-walled carbon nanotubes by photo-excitation.

Abstract: Compositions and methods are provided for prognostic classification of rheumatoid arthritis disease patients into subtypes, which subtypes are informative of the patient's need for therapy and responsiveness to a therapy of interest.

Abstract: Electromagnetic energy transfer is facilitated. In accordance with an example embodiment, a first resonator transmits electromagnetic energy using an electromagnetic wave, based on frequency matching and alignment of an electromagnetic field with a second resonator within a distance of one wavelength of the electromagnetic wave from the first resonator. An electromagnetic energy reflector adjacent the first resonator redirects reflected portions of the electromagnetic wave back towards the first resonator.

Abstract: Provided herein are methods for detecting, quantifying, differentiating, diagnosing and imaging pathogenic bacteria or condition associated therewith using substrates for bacterial enzymes. Fluorescent, luminescent or colorimetric signals emitted by substrates or enzyme products in the presence of the bacteria are compared to controls to detect and locate the pathogenic bacteria. Provided is a method for screening therapeutic agents to treat the pathophysiological conditions by measuring a signal emitted from the substrates or products in the presence and absence of the potential therapeutic agent and a diagnostic method for detecting a mycobacterial infection in a subject by contacting biological samples with a substrate and imaging for signals emitted from a mycobacterial beta-lactamase product. Also provided are fluorogenic substrates or substrates comprising a colored dye or a chemical reagent effective to induce a color or pH change.

Abstract: A light field sensor for a 4D light field camera has a layer of nanoscale resonator detector elements, such as silicon nanoshells, below a layer of dielectric microlenses. By taking advantage of photonic nanojets in the microlenses and circulating resonances in nanoshells, the light field camera sensor achieves improved sensitivity, pixel density, and directional resolution even at large angles of incidence.

Abstract: As consistent with various embodiments, an electronic device includes a fibrous material having a conductive coating thereon. The conductive coating includes conductive nanoparticles coupled to fibers in the fibrous material. The structure is implemented in connection with a variety of devices, such as a capacitive device or a battery. Other embodiments are directed to forming conductive fibrous sheets, in dispersing a nanomaterial in a solution and applying the solution to a fibrous sheet, such as commercial paper, to form a conductive sheet.

Abstract: Compositions of purified biologically active Wnt proteins are provided. Wnt proteins are found to be hydrophobic and post-translationally modified by addition of a lipid moiety at a conserved cysteine residue. Methods for isolation of Wnt utilize detergents that maintain the solubility of the modified protein.

Abstract: Indwelling body lumen expanders which allow for the maintenance and patency of a body lumen, such as the prostatic urethra to relieve urethral obstruction, are described. Because the one or more expanders are configured to be relatively larger in diameter than the diameter of the body lumen, the expanders may become invaginated into the lumen wall thus enabling the prostheses to avoid fluid exposure which in turn prevent the prostheses from becoming encrusted or calcified.

Abstract: Compositions of a fusion protein comprising a spatially tethered ferredoxin-NADP-reductase (FNR) and an active [FeFe] hydrogenase, genetic sequences encoding such fusion proteins, and methods of use thereof are provided. The fusion proteins of the invention link an FNR polypeptide to an active [FeFe] hydrogenase through a polypeptide linker. The fusion protein facilitates improved electron transfer through a ferredoxin, and allows direct electron transfer from NADPH to the hydrogenase.

Abstract: In accordance with various embodiments, an organic electronic device includes an n-type dopant material including an imidazole-based material having a hydrogen-based material bonded between nitrogen atoms. The n-type dopant material n-dopes an organic material, and can be used to mitigate degradation in mobility due to conditions such as exposure to ambient atmosphere, which can effect an undesirable reduction in charge transport. Other embodiments are directed to carbon nanotubes or graphene structures with this type of n-type dopant, wherein the Fermi level for the carbon nanotubes or graphene structures is below ?2.5 eV to effect such n-type doping.

Abstract: Compound tunneling field effect transistors integrated on a silicon substrate are provided with increased tunneling efficiency and an abrupt band slope by forming a source region with a material having a bandgap at least 0.4 electron volts (eV) narrower than that of silicon to increase a driving current (ON current) by forming a channel region with a material having almost no difference in lattice constant from a source region and having a high electron mobility at least 5 times higher than silicon. ON/OFF current ratio simultaneously is increased by forming a drain region with a material having a bandgap at least as wide as a channel region material to restrain OFF current. Tunneling field effect transistors having various threshold voltages according to circuit designs are formed easily by adding a specific material with an electron affinity less than a source region material when forming a channel region.

Abstract: Device and method for rapid extraction of body tissue from an enclosed body cavity. Hollow entry cannula with optional core element provides entry into body tissue space such as bone marrow. Aspiration cannula is inserted through the hollow entry cannula into the body tissue and is manipulated to advance directionally through the body cavity. Optional stylet within the aspiration cannula aids in advancing the aspiration cannula through the body tissue and is removed to facilitate extraction of the body tissue through the aspiration cannula. Inlet openings near the distal tip of the aspiration cannula allow tissue aspiration, with negative pressure source at the proximal end of the aspiration cannula providing controlled negative pressure. The aspiration cannula may be withdrawn and its path adjusted for multiple entries through a same entry point, following different paths through the tissue space for subsequent aspiration of more tissue.

Abstract: The present invention pertains to an apparatus and method for delivering radiation to a human patient or other mammal. A scanning electron beam x-ray source is used and the detector can be a photon counting detector. The area of the detector is less than the area of field of view in the patient. Tomosynthesis can be used to generate images and images can be produced rapidly in real time.

Abstract: Aspects of the disclosure include methods for analyzing an analyte composition by mass spectrometry employing a macroporous metal organic polymer matrix. In practicing methods according to certain embodiments an analyte composition is applied to a macroporous metal organic polymer matrix, a voltage is applied to the macroporous metal organic polymer matrix sufficient to produce and expel analyte ions from the macroporous metal organic polymer matrix and the analyte ions are analyzed by mass spectrometry. In other embodiments, a composition having biological macromolecules is applied onto a surface-modified macroporous metal organic polymer matrix and analytes produced by reaction (e.g., enzymatic cleavage of the biological macromolecules) at or near the surface of the macroporous metal organic polymer matrix are measured by mass spectrometry.

Abstract: Devices, systems and methods for dynamically stabilizing the spine are provided. The devices include an expandable spacer having an undeployed configuration and a deployed configuration, wherein the spacer has axial and radial dimensions for positioning between the spinous processes of adjacent vertebrae. The systems include one or more spacers and a mechanical actuation means for delivering and deploying the spacer. The methods involve the implantation of one or more spacers within the interspinous space.

Abstract: The present disclosure provides a method of making a mammal (e.g., a rodent, such as a mouse) by integrating an intact polynucleotide sequence into a specific genomic locus of the mammal to result in a transgenic mammal. A transgenic mammal made by the methods of the present disclosure would contain a known copy number (e.g., one) of the inserted polynucleotide sequence at a predetermined location. The method involves introducing a site-specific recombinase and a targeting construct, containing a first recombination site and the polynucleotide sequence of interest, into the mammalian cell. The genome of the cell contains a second recombination site and recombination between the first and second recombination sites is facilitated by the site-specific, uni-directional recombinase. The result of the recombination is site-specific integration of the polynucleotide sequence of interest in the genome of the mammal. This inserted sequence is then also transmitted to the progeny of the mammal.

Abstract: Various apparatuses, systems and methods involve high mobility materials. In accordance with one or more example embodiments, a material includes a conjugated molecule and a side chain bonded to the conjugated molecule. The side chain includes at least one of a siloxane-terminated unit and a derivative of a siloxane-terminated unit that enhance solubility of the conjugated molecule. Further, the side chain facilitates a ?-stacking distance between the conjugated molecules when stacked (e.g., in an organic semiconductor film), thereby facilitating carrier mobility between the conjugated molecules.

Abstract: A 5-dimensional imaging method and system is provided to acquire and display the effect of dynamic physiologic changes (either spontaneous or induced) on cardiac function of a patient's heart to elucidate their effects on diastolic myocardial function. In a patient free-breathing magnetic resonance imaging study, 3-dimensional spatial information is encoded by a non-Cartesian 3-dimensional k-space readout trajectory and acquired concurrently with recordings of cardiac and respiratory cycles. The advantage of using non-Cartesian sampling in this invention compared to, for example, Cartesian sampling is higher scan acceleration, improved robustness to motion/flow effects (incoherent instead of coherent artifacts) and robustness to missing data points in k-space.

Abstract: A thermoelectronic energy converter device (100) comprises an electron emitter (11) being adapted for a temperature-dependent release of electrons (1), an electron collector (21) being adapted for collecting the electrons (1), wherein the electron collector (21) is spaced from the electron emitter (11) by an evacuated gap (2), a gate electrode (31) being arranged between the electron emitter (11) and the electron collector (21) for subjecting the electrons (1) in the gap (2) to an accelerating electric potential, wherein the gate electrode (31) has a plurality of electrode openings (34) being arranged for transmitting electrons (1) miming from the electron emitter (11) to the electron collector (21), and a magnetic field device (50) being arranged for creating a magnetic field with magnetic field lines extending between the electron emitter and the electron collector (11, 21), wherein the magnetic field device (50) is arranged such that at least a portion of the magnetic field lines pass through the electrode

Abstract: Cancer treatment is provided, by irradiating an individual with a localized, high single dose or short course of doses at a primary tumor site; collecting T cells from the individual after a period of time sufficient activation of an anti-tumor response; treating the individual with an effective dose of dose of chemotherapy; and reintroducing the T cell population back to the individual.