Patents Assigned to Bowling Green State University
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Patent number: 7553945Abstract: The invention includes RNA complexes comprising at least three monomeric units of an RNA molecule, each monomeric unit comprising an RNA polymer having first and second helical domains that have respective first and second binding sites, wherein the first binding sites are adapted to binding to one another and are not adapted to bind to the second binding sites, and the second binding sites are adapted to binding to one another and are not adapted to bind to the first binding sites; such that the at least three monomeric units are adapted to self-assemble by forming pairs of cognate interactions and so as to form the RNA complex in a circular closed complex. The invention also includes derivatives of these complexes including aptamers, and analytical methods and devices using same.Type: GrantFiled: August 3, 2005Date of Patent: June 30, 2009Assignee: Bowling Green State UniversityInventor: Neocles Leontis
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Publication number: 20080317700Abstract: The present invention holds forth improvements in the field of herbicide synthesis, their application, and methods of plant and weed control and antifouling. The present invention includes the synthesis of new acrylate and methacrylate derivatives of a glyphosate. Two isomers resulting from a hindered rotation around the amide CN bond are observed for both acrylic and methacrylic analogs and barriers for internal rotation are obtained. Biological activity tests indicate that functionalized glyphosates possess herbicidal activity similar to the parent compound.Type: ApplicationFiled: December 21, 2007Publication date: December 25, 2008Applicant: Bowling Green State UniversityInventors: Douglas C. Neckers, Aneta Bogdanova, Andrei V. Fedorov
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Publication number: 20070209850Abstract: The present invention is a method and apparatus by which power is controlled in a hybrid electric vehicle such that high levels of performance and efficiency are realized. The present invention includes a method and apparatus developed to optimize the use of energy in a hybrid vehicle application from the hybrid energy storage device. The method and apparatus of the present invention is particularly useful with energy storage devices there the energy state, such as the state of charge, is readily determined by an easily measured attribute. Ultracapacitors and hydraulic storage cylinders are examples of the types of energy storage devices to which the present invention may be applied.Type: ApplicationFiled: March 13, 2006Publication date: September 13, 2007Applicant: Bowling Green State UniversityInventor: Aaron Bloomfield
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Publication number: 20070196579Abstract: The present invention is a method and apparatus for remote curing of resin-coated surfaces and articles by means of a vaporous curing agent. The method of the present invention includes the steps: (a) providing a surface of the substrate with a layer of a coating precursor comprising a curable material and a stabilized curing agent that is adapted to react with a gaseous, vaporous or aerosol initiating agent to activate the stabilized curing agent so as to cause the curable material to undergo a curing reaction; (b) subjecting the coating precursor to the gaseous, vaporous or aerosol initiating agent for sufficient time to initiate the curing reaction, and allowing the coating precursor to form a cured coating on the substrate. Another variation of the method of the present invention involves the reversal of the positions of the active compounds utilizing the interaction between the gaseous, vaporous or aerosol curing agent and coating precursor comprising a curable material and initiating agent.Type: ApplicationFiled: February 23, 2006Publication date: August 23, 2007Applicant: Bowling Green State UniversityInventors: Douglas Neckers, Andrei Fedorov, Andrey Ermoshkin
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Patent number: 7252165Abstract: A hybrid electric propulsion system for powering a vehicle using a natural fuel engine and an electric motor. The hybrid electric vehicle is comprised of a drive train; an electric motor for driving the drive train; an auxiliary power unit (APU); an electric energy storage system electrically coupled to the electric motor; and wherein the auxiliary power unit and the electric energy storage system provide energy for powering the vehicle. An electric bus is directly connected to both the auxiliary power unit and the electric energy source and the voltage across the electric bus is substantially the same as the voltage across the electric energy source so that a change in voltage of the electric bus results in the same change to the voltage across the electric energy source. A power management controller is programmed to control output power of the power unit to maintain the energy storage system between a predetermined high voltage set-point and a predetermined low voltage set-point.Type: GrantFiled: February 24, 2006Date of Patent: August 7, 2007Assignee: Bowling Green State UniversityInventors: Robert Gruenwald, Jeff T. Major, Anthony J. Palumbo
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Patent number: 7132254Abstract: The present invention relates to a method of detecting phycocyanin algae or bacteria in water from reflected light, and also includes devices for the measurement, calculation and transmission of data relating to that method.Type: GrantFiled: January 22, 2004Date of Patent: November 7, 2006Assignee: Bowling Green State UniversityInventor: Robert Vincent
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Patent number: 6651759Abstract: A hybrid electric propulsion system for powering a vehicle using a natural fuel engine and an electric motor. The hybrid electric vehicle is comprised of a drive train; an electric motor for driving the drive train; an auxiliary power unit (APU); an electric energy storage system electrically coupled to the electric motor; and wherein the auxiliary power unit and the electric energy storage system provide energy for powering the vehicle. An electric bus is directly connected to both the auxiliary power unit and the electric energy source and the voltage across the electric bus is substantially the same as the voltage across the electric energy source so that a change in voltage of the electric bus results in the same change to the voltage across the electric energy source. A power management controller is programmed to control output power of the power unit to maintain the energy storage system between a predetermined high voltage set-point and a predetermined low voltage set-point.Type: GrantFiled: October 1, 2002Date of Patent: November 25, 2003Assignee: Bowling Green State UniversityInventors: Robert Gruenwald, Jeff T. Major, Anthony J. Palumbo
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Patent number: 6484830Abstract: A hybrid electric propulsion system for powering a vehicle using a natural fuel engine and an electric motor. The hybrid electric vehicle is comprised of a drive train; an electric motor for driving the drive train; an auxiliary power unit (APU); an electric energy storage system electrically coupled to the electric motor; and wherein the auxiliary power unit and the electric energy storage system provide energy for powering the vehicle. An electric bus is directly connected to both the auxiliary power unit and the electric energy source and the voltage across the electric bus is substantially the same as the voltage across the electric energy source so that a change in voltage of the electric bus results in the same change to the voltage across the electric energy source. A power management controller is programmed to control output power of the power unit to maintain the energy storage system between a predetermined high voltage set-point and a predetermined low voltage set-point.Type: GrantFiled: April 26, 2000Date of Patent: November 26, 2002Assignee: Bowling Green State UniversityInventors: Robert Gruenwald, Jeff T. Major, Anthony J. Palumbo
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Patent number: 6225333Abstract: The present invention in general terms includes a method of treating cancerous cells containing a pigment, the method including irradiation of the cells with light of comprising the steps: (1) subjecting the cancerous cells to relatively high power light so as to substantially reduce the amount of the pigment in the cells; (2) treating the cancerous cells with one or more photosensitizing agent; followed by (3) subjecting the cancerous cells to relatively low power light so as to activate the photosensitizing agent(s).Type: GrantFiled: March 14, 2000Date of Patent: May 1, 2001Assignee: Bowling Green State UniversityInventors: Michael A. J. Rodgers, Giulio Jori, Malcolm E. Kenney
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Patent number: 6071944Abstract: The present invention in general terms includes a method of treating cancerous cells containing a pigment, the method including irradiation of the cells with light of comprising the steps: (1) subjecting the cancerous cells to relatively high power light so as to substantially reduce the amount of the pigment in the cells; (2) treating the cancerous cells with one or more photosensitizing agent; followed by (3) subjecting the cancerous cells to relatively low power light so as to activate the photosensitizing agent(s).Type: GrantFiled: November 12, 1997Date of Patent: June 6, 2000Assignee: Bowling Green State UniversityInventors: Michael A. J. Rodgers, Giulio Jori, Malcolm E. Kenney
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Patent number: 5032572Abstract: Polymers from ethylenically unsaturated monomers, cross-linked by a substituted divinylazobenzene are useful as pharmaceutical compositions for the delivery of medicaments. The polymers are degraded by the enzymes of the upper gastrointestinal tract or are transferred intact past the upper gastrointestinal tract, to deliver the medicament to the large intestine. In particular, the polymers contain divinylazobenzene compounds of the formulae ##STR1## wherein R.sub.1 and R.sub.2 are independently selected from the group consisting of H, (except that R.sub.1 and R.sub.2 are not both H), Cl, Br, I, NO.sub.2, NH.sub.2, RO, ArO, COOH or salts thereof, COOR, COOAr, CHO, COR, SO.sub.3 H or salts thereof, R or Ar and wherein R is alkyl of up to 18 carbon atoms and Ar is mono- or bicyclic aryl of up to 15 carbon atoms.Type: GrantFiled: August 12, 1988Date of Patent: July 16, 1991Assignees: Medical College of Ohio, Bowling Green State UniversityInventors: Murray Saffran, Douglas C. Neckers
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Patent number: 4924009Abstract: Photooxidizable dye complexes of the formula (I):X.sup.-n [Y.sup.+ ].sub.n (I)where X is a xanthene dye and Y is gegen ion selected from sulfonium, phosphonium, iodonium, pyrylium, hydrazinium, and hydrazide ions; and n is 1 to 2; the complexes are useful as photoinitiators or in photobleachable imaging systems.Type: GrantFiled: June 3, 1987Date of Patent: May 8, 1990Assignee: Bowling Green State UniversityInventors: Douglas C. Neckers, Shwn M. Y. Linden
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Patent number: 4831188Abstract: Peresters of the formula: R.sub.1 Ar COOOR wherein R is an alkyl group; Ar is selected from the group including phenyl (unsubstituted or substituted) groups, naphthyl groups, anthryl groups, pyryl groups, phenanthryl groups, or heterocyclic groups; and R.sub.1 is any group absorbing radiation between 250 and 800 nm such that R.sub.1 produces an excited state of sufficient lifetime to cause the decomposition to free radicals of the appended perester or peroxidic function.Type: GrantFiled: January 20, 1987Date of Patent: May 16, 1989Assignee: Bowling Green State UniversityInventor: Douglas C. Neckers
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Patent number: 4752649Abstract: Peresters of the formula: ROOC--R.sub.1 --COOOR wherein R is an alkyl group; R.sub.1 is selected from the group including ketone (unsubstituted or substituted) groups, and R.sub.1 is any group absorbing radiation between 250 and 800 nm such that R.sub.1 produces an excited state of sufficient lifetime to cause the decomposition to free radicals of the appended perester or peroxidic function.Type: GrantFiled: August 27, 1984Date of Patent: June 21, 1988Assignee: Bowling Green State UniversityInventor: Douglas Neckers
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Patent number: 4663308Abstract: Polymers from ethylenically unsaturated monomers, cross-linked by a substituted or unsubstituted divinylazobenzene are useful as carriers or capsules for medicaments, which are degraded by the enzymes of the upper gastrointestinal tract or which must be transferred intact past the upper gastrointestinal tract, to deliver the medicament to the large intestine.Polymers containing monomeric units of the formulaH.sub.2 C.dbd.CH--C.sub.6 H.sub.4 --N.dbd.N--M,wherein M is the residue of an amino-containing medicament, are useful as carriers for therapeutic agents or as therapeutic agents per se.Type: GrantFiled: July 18, 1984Date of Patent: May 5, 1987Assignees: Medical College of Ohio, Bowling Green State UniversityInventors: Murray Saffran, Douglas C. Neckers
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Patent number: 4498963Abstract: Peresters of the formula: ##STR1## wherein R is an alkyl group; and ##STR2## is a light-absorbing chromophore group; and use thereof as photoinitiators are provided.Type: GrantFiled: August 29, 1983Date of Patent: February 12, 1985Assignee: Bowling Green State UniversityInventor: Douglas C. Neckers