Patents Assigned to Brookhaven Science Associates LLC
  • Patent number: 10502842
    Abstract: Technologies are described for semiconductor radiation detectors. The semiconductor radiation detectors may comprise a semiconductor material. The semiconductor material may include a first surface and a second surface. The first surface may be opposite from the second surface. The semiconductor material may include at least one metal component. The semiconductor material may be effective to absorb radiation and induce a current pulse in response thereto. The semiconductor radiation detector may comprise an electrode contact. The electrode contact may include a metal doped oxide deposited on the first surface of the semiconductor material. The metal doped oxide may include the metal component element of the semiconductor material.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: December 10, 2019
    Assignees: BROOKHAVEN SCIENCE ASSOCIATES, LLC, NORFOLK STATE UNIVERSITY
    Inventors: Utpal N. Roy, Ralph B. James, Giuseppe Camarda, Yonggang Cui, Anwar Hossain, Ge Yang, Aswini Pradhan, Rajeh Mundle
  • Patent number: 10501321
    Abstract: Nitride stabilized metal nanoparticles and methods for their manufacture are disclosed. In one embodiment the metal nanoparticles have a continuous and nonporous noble metal shell with a nitride-stabilized non-noble metal core. The nitride-stabilized core provides a stabilizing effect under high oxidizing conditions suppressing the noble metal dissolution during potential cycling.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: December 10, 2019
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Kurian Abraham Kuttiyiel, Kotaro Sasaki, Radoslav R. Adzic
  • Patent number: 10395789
    Abstract: Technologies are described for apparatus, methods and systems effective for filtering. The filters may comprise a first plate. The first plate may include an x-ray absorbing material and walls defining first slits. The first slits may include arc shaped openings through the first plate. The walls of the first plate may be configured to absorb at least some of first x-rays when the first x-rays are incident on the x-ray absorbing material, and to output second x-rays. The filters may comprise a second plate spaced from the first plate. The second plate may include the x-ray absorbing material and walls defining second slits. The second slits may include arc shaped openings through the second plate. The walls of the second plate may be configured to absorb at least some of second x-rays and to output third x-rays.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: August 27, 2019
    Assignees: Brookhaven Science Associates, LLC, UChicago Argonne, LLC
    Inventors: John Jay Sinsheimer, Raymond P. Conley, Nathalie Christine Dominique Bouet, Eric Y. Dooryhee, Sanjit K. Ghose
  • Patent number: 10351868
    Abstract: Heterologous expression of E. coli cyclopropane synthase in genotypic and phenotypic fad2fae1 plants facilitates accumulation of cyclopropane fatty acids. Co-expression of Sterculia foetida transferases, including lysophosphatidic acid acyltransferase, diacylglycerol acyltransferase (DGAT), and Phospholipid Diacyl Glycerol Acyltransferase (PDAT), with E. coli cyclopropane synthase further enhances cyclopropane fatty acid accumulation in fad2fae1 plant seeds.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: July 16, 2019
    Assignee: Brookhaven Science Associates, LLC
    Inventors: John Shanklin, Xiao-Hong Yu, Richa Rawat Prakash
  • Patent number: 10333017
    Abstract: Thin-film photovoltaic devices and methods of their use and manufacture are disclosed. More particularly, polycrystalline CuIn(1-x)GaxSe2 (CIGS) based thin-film photovoltaic devices having independently tunable sublayers are disclosed. Also provided are methods of producing an n-doped graphene.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: June 25, 2019
    Assignees: Brookhaven Science Associates, LLC, The Research Foundation for the State University of New York
    Inventors: Nanditha M. Dissanayake, Matthew Eisaman, Ahsan Ashraf, Nancy Goroff, Xiuzhu Ang
  • Patent number: 10290507
    Abstract: Technologies are described for methods and systems effective for etching nanostructures in a substrate. The methods may comprise depositing a patterned block copolymer on the substrate. The patterned block copolymer may include first and second polymer block domains. The methods may comprise applying a precursor to the patterned block copolymer to generate an infiltrated block copolymer. The precursor may infiltrate into the first polymer block domain and generate a material in the first polymer block domain. The methods may comprise applying a removal agent to the infiltrated block copolymer to generate a patterned material. The removal agent may be effective to remove the first and second polymer block domains from the substrate. The methods may comprise etching the substrate. The patterned material on the substrate may mask the substrate to pattern the etching. The etching may be performed under conditions to produce nanostructures in the substrate.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: May 14, 2019
    Assignee: BROOKHAVEN SCIENCE ASSOCIATES, LLC
    Inventors: Charles T. Black, Atikur Rahman, Matthew Eisaman, Ahsan Ashraf
  • Patent number: 10281069
    Abstract: Flange technologies are described for a flange comprising a first and second side. Each side may include a knife edge surface disposed circumferentially around a base surface and a periphery section disposed around the knife edge surface. The knife edge surface and the periphery section are effective to define grooves therebetween. The flange may include an alloy with a relatively high thermal conductivity and yield strength. The flange may include water channels to remove heat.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: May 7, 2019
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Sushil Kumar Sharma, Lewis Garth Doom, Jr., Christopher Amundsen, Muhammad Aftab Hussain, Frank A. DePaola, Frank Charles Lincoln, Charles Hetzel, Charles S. De La Parra, Paul Edward Palecek, Jr.
  • Patent number: 10246499
    Abstract: A composition comprising a synthetic growth factor analogue comprising a non-growth factor heparin binding region, a linker and a sequence that binds specifically to a cell surface receptor and an osteoconductive material where the synthetic growth factor analogue is attached to and can be released from the osteoconductive material and is an amplifier/co-activator of osteoinduction.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: April 2, 2019
    Assignees: Ferring B.V., Brookhaven Science Associates, LLC
    Inventors: Paul Zamora, Brent Lee Atkinson, Xinhua Lin, Louis A. Pena
  • Patent number: 10242770
    Abstract: A method for producing a long length high temperature superconductor wire, includes providing a substrate, having a surface with a length of at least 50 meters and a width. The surface supports a biaxially textured high temperature superconducting layer and the biaxially textured high temperature superconducting layer has a length and a width corresponding to the length and width of the surface of the substrate. The method includes irradiating the biaxially textured high temperature superconductor layer with an ion beam impinging uniformly along the length and across the width of the biaxially textured high temperature superconductor layer to produce a uniform distribution of pinning microstructures in the biaxially textured high temperature superconductor layer.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: March 26, 2019
    Assignees: American Superconductor Corporation, Brookhaven Science Associates, LLC
    Inventors: Martin W. Rupich, Srivatsan Sathyamurthy, Qiang Li, Vyacheslav F. Solovyov
  • Patent number: 10189704
    Abstract: Technologies are described for methods and systems effective for etching nanostructures in a substrate. The methods may comprise depositing a patterned block copolymer on the substrate. The methods may comprise applying a precursor to the patterned block copolymer to generate an infiltrated block copolymer. The precursor may infiltrate into the first polymer block domain and generate a material. The methods may comprise applying a removal agent effective to remove the polymer block domains to the infiltrated block copolymer to generate a pattern of the material. The methods may comprise etching the substrate. The pattern of the material may mask the substrate to pattern the etching. The etching may be performed under conditions to produce nanostructures in the substrate. The methods may comprise removing the pattern of the material and coating the nanostructures and the surface of the substrate with a hydrophobic coating.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: January 29, 2019
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Antonio Checco, Charles T. Black, Atikur Rahman, Benjamin M. Ocko
  • Patent number: 10132942
    Abstract: TOF-PET detector systems, and methods for imaging photon-emitting samples using the detector systems, are provided. The TOF-PET detector systems use large-area photodetectors with extremely high time-resolution and an approach to data collection and analysis that allows for the use of inexpensive low-density scintillator materials. The TOF-PET detector systems are characterized by their ability to identify, on a statistical basis, the transverse and depth location of the first of the series of energy deposition events that are generated when a gamma photon enters the low-density scintillator material.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: November 20, 2018
    Assignees: The University of Chicago, Brookhaven Science Associates, LLC
    Inventors: Henry J. Frisch, Eric J. Oberla, Hee-Jong Kim, Minfang Yeh
  • Patent number: 10126652
    Abstract: This disclosure provides embodiments of an approach that enforces coexistence of multiple, aligned block copolymer morphologies within a single patterning layer.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: November 13, 2018
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Charles Thomas Black, Aaron Stein, Gwen Wright, Kevin G. Yager
  • Patent number: 10126167
    Abstract: Technologies are described for methods and systems effective to detect photon receiving events. A first comparator may compare a magnitude of a photon signal to a first threshold voltage to produce a first output. A second comparator may compare the magnitude of the photon signal to a second threshold voltage to produce a second output. A counter control circuit may increment a second counter in response to a determination that the magnitude of a first peak of the photon signal exceeds and then falls below the second threshold voltage. The counter control circuit may prevent a third counter from incrementing in response to a second peak of the photon signal. The counter control circuit may increment the first counter in response to the magnitude of the signal exceeding and then falling below the first threshold voltage. The first counter may be associated with a number of photon receiving events detected.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: November 13, 2018
    Assignee: Brookhaven Science Associates, LLC
    Inventor: Gianluigi De Geronimo
  • Publication number: 20180296656
    Abstract: The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies. The invention also provides methods for administering the chimeric OspA molecules to a subject in the prevention and treatment of Lyme disease or borreliosis.
    Type: Application
    Filed: January 19, 2018
    Publication date: October 18, 2018
    Applicants: BROOKHAVEN SCIENCE ASSOCIATE, LLC, RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK
    Inventors: Brian A. Crowe, Ian Livey, Maria O'rourke, Michael Schwendinger, John J Dunn, Benjamin J Luft
  • Patent number: 10049848
    Abstract: Technologies are described for methods for fabricating a film component. The methods may comprise sputtering a first film onto a substrate. The first film may include a semiconductor compound material. The semiconductor compound material may include a semi-metal material and one or more alkali material. The methods may further comprise evaporating a second film onto the first film. The second film may include the one or more alkali materials. The one or more alkali materials may catalyze crystallization of the semiconductor compound material in the first film substantially throughout the first film to form the film component in the first layer.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: August 14, 2018
    Assignees: Brookhaven Science Associates, LLC, The Regents of the University of California
    Inventors: John Smedley, Klaus Attenkofer, Susanne Schubert, Mengjia Gaowei, John Walsh
  • Patent number: 9976155
    Abstract: Compositions and methods include genetically encoding and expressing a novel ?9-18:0-ACP desaturase in plant cells. In some embodiments, nucleic acid molecules encode the novel ?9-18:0-ACP desaturase. In other embodiments, amino acid sequences have ?9-18:0-ACP desaturase activity. Methods can involve expression of ?9-18:0-ACP desaturase in plant cells, plant materials, and whole plants for the purpose of increasing the amount of unusual fatty acids in whole plants, plant seeds, and plant materials, for example, seeds.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: May 22, 2018
    Assignees: Dow AgroSciences LLC, Brookhaven Science Associates, LLC
    Inventors: John Shanklin, Tam Huu Nguyen, Terence A. Walsh, Mark S. Pidkowich, Edward J. Whittle
  • Patent number: 9976199
    Abstract: Embodiments of the disclosure relate to intermetallic nanoparticles. Embodiments include nanoparticles having an intermetallic core including a first metal and a second metal. The first metal may be palladium and the second metal may be at least one of cobalt, iron, nickel, or a combination thereof. The nanoparticles may further have a shell that includes palladium and gold.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: May 22, 2018
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Kurian A. Kuttiyiel, Kotaro Sasaki, Radoslav R. Adzic
  • Patent number: 9957514
    Abstract: The present disclosure provides methods and compositions for genetic transformation of Lemnaceae species.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: May 1, 2018
    Assignees: Cold Spring Harbor Laboratory, Brookhaven Science Associates, LLC
    Inventors: Rob Martienssen, Almudena Molla-Morales, Alex Cantó-Pastor, Evan Ernst, John Shanklin, Yiheng Yan
  • Patent number: 9916958
    Abstract: Methods and systems for fabricating a film, such as, for example, a photocathode, having a tailored band structure and thin-film components that can be tailored for specific applications, such as, for example photocathode having a high quantum efficiency, and simple components fabricated by those methods.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: March 13, 2018
    Assignees: RADIATION MONITORING DEVICES, INC., THE UNIVERSITY OF CHICAGO, BROOKHAVEN SCIENCE ASSOCIATES, LLC
    Inventors: Harish B. Bhandari, Vivek V. Nagarkar, Olena E. Ovechkina, Henry J. Frisch, Klaus Attenkofer, John M. Smedley
  • Patent number: 9895434
    Abstract: The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies. The invention also provides methods for administering the chimeric OspA molecules to a subject in the prevention and treatment of Lyme disease or borreliosis.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: February 20, 2018
    Assignees: Research Foundation of the State University of New York, Brookhaven Science Associates, LLC
    Inventors: Brian A. Crowe, Ian Livey, Maria O'Rourke, Michael Schwendinger, John J. Dunn, Benjamin J. Luft