Patents Assigned to Byk Gulden Lomberg Chemische Fabrik GmbH
  • Process for the production of powdered pulmonary surfactant preparations
    Patent number: 6315983
    Abstract: A powdered pulmonary surfactant preparation containing a hydrophobic protein serving as a pulmonary surfactant is obtained by spray drying an organic solution or suspension containing a hydrophobic protein serving as a pulmonary surfactant and possibly other components. Obtained power preparations exhibit very good stability under storage, are easy to reconstitute and are also suitable for administration by inhalation.
    Type: Grant
    Filed: July 24, 1998
    Date of Patent: November 13, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Klaus Eistetter
  • Imidazo- and oxazolopyridines
    Patent number: 6306867
    Abstract: are useful for preventing or treating airway disorders, dermatoses, disorders based on excessive release of TNF and leukotrienes, disorders of the immune system and generalized inflammation in the gastrointestinal area.
    Type: Grant
    Filed: October 4, 2000
    Date of Patent: October 23, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Thomas Bär, Wolf-Rüdiger Ulrich
  • Proton pump inhibitor in therapeutic combination with antibacterial substances
    Patent number: 6303644
    Abstract: The invention relates to the use of proton pump inhibitors as combination therapeutics in the treatment of bacterial diseases which do not affect the gastrointestinal track using antibacterially active compounds.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: October 16, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Klaus Tuch
  • Benzamides with tetrahydrofuranyloxy substitutents as phosphodiesterase 4 inhibitors
    Patent number: 6303789
    Abstract: Compounds of the formula I in which R1, R2, R3, R4, R5, m and n have the meanings cited in the description, are novel effective PDE-inhibitors.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: October 16, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Thomas Bär
  • Benzimidazoles and benzoxazoles
    Patent number: 6294564
    Abstract: The invention relates to compounds of formula (I) wherein R1, R2, R3, R4 and Y have the meanings given in the description. Said compounds are novel active bronchial therapeutic agents.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: September 25, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Thomas Bär
  • Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole
    Patent number: 6274173
    Abstract: An oral pharmaceutical composition comprises an acid-labile irreversible proton pump inhibitor in pellet or tablet form, wherein the irreversible proton pump inhibitor is at least partly in slow-release form. On combined administration with an anti-microbially-active ingredient, the composition is distinguished by imparting an enhanced action of rapid onset against disorders caused by Helicobacter.
    Type: Grant
    Filed: December 15, 1999
    Date of Patent: August 14, 2001
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventors: George Sachs, Rango Dietrich
  • Phthalazinone PDE III/IV inhibitors
    Patent number: 6255303
    Abstract: The compounds of formula (I) in which R1, R2, R3, R4, R5, X and Y have the meanings as given in the description are novel effective bronchial therapeutica.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: July 3, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Geert Jan Sterk, Margaretha van der Mey
  • Substituted 6-alkylphenanthridines
    Patent number: 6214839
    Abstract: Compounds of formula I pharmaceutically acceptable salts thereof and compositions of either are useful for treating conditions amenable to treatment with a phosphodiesterase inhibitor type 4.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: April 10, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Beate Gutterer
  • Benzofuran-4-carboxamides
    Patent number: 6211203
    Abstract: Compounds of formula I wherein R1 is 1-2C-alkoxy optionally substituted by flourine, R2 is methyl, 1-methylethyl, 3-7C-cycloalkyl or 3-7Ccycloalkylmethyl and Ar is a pyridyl which is optionally di-halo substituted.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: April 3, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Hermann Amschler
  • Tetrahydropyrido compounds
    Patent number: 6197783
    Abstract: Tetrahydropyrido compounds of formula (I) in which the substituents have the meanings mentioned in the description, are suitable for the prevention or treatment of gastrointestinal diseases.
    Type: Grant
    Filed: September 24, 1999
    Date of Patent: March 6, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Jörg Senn-Bilfinger, Gerhard Grundler
  • Phenanthridines
    Patent number: 6191138
    Abstract: Compounds of formula (I), where R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings given in the description, are new active bronchial therapeutic agents.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: February 20, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Beate Gutterer
  • Imidazopyridines and oxazolopyridines
    Patent number: 6172074
    Abstract: Compounds of formula (I), wherein A, B, D, E, R1, R2, R3 and Y have the meanings cited in the description, are effective bronchial therapeutic agents.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: January 9, 2001
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Thomas B{umlaut over (a)}r, Wolf-R{umlaut over (u)}diger Ulrich
  • Pyridylthio compounds for controlling helicobacter bacteria
    Patent number: 6162809
    Abstract: Pyridinylthiomethyl- and pyrimidinylthiomethyl-pyridines and their pharmacologically-acceptable compositions are useful for controlling Helicobacter bacteria and for treating those afflicted with diseases based on Helicobacter bacteria.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: December 19, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Bernhard Kohl, Gerhard Grundler, Jorg Senn-Bilfinger
  • Fused dihydropyrans
    Patent number: 6160119
    Abstract: Compounds of formula (I) in which the substituents have the meanings mentioned in the specification, are suitable for the prevention and treatment of gastrointestinal diseases.
    Type: Grant
    Filed: November 16, 1999
    Date of Patent: December 12, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Jorg Senn-Bilfinger
  • Tetrazoles
    Patent number: 6143759
    Abstract: Compounds of formula (I) in which R.sup.4 is a phenyl radical substituted by R.sup.5, where R.sup.5 is a tetrazole-5-yl-radical optionally substituted by a radical R.sup.6, are novel efficacious PDE3/4 inhibitiors.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: November 7, 2000
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Dieter Flockerzi
  • Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors
    Patent number: 6132768
    Abstract: An oral pharmaceutical composition of a reversible proton pump inhibitor in pellet or tablet form, wherein the reversible proton pump inhibitor is at least partly in slow-release form, is distinguished, on combined administration with an antimicrobially-active ingredient, by an enhanced action of rapid onset against disorders caused by Helicobacter.
    Type: Grant
    Filed: July 5, 1995
    Date of Patent: October 17, 2000
    Assignee: BYK Gulden Lomberg Chemische Fabrik GmbH
    Inventors: George Sachs, Rango Dietrich
  • Phenanthridines substituted in the 6 position
    Patent number: 6127378
    Abstract: Compounds of the formula I in which R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings indicated in the description, are novel efficacious bronchial therapeutics.
    Type: Grant
    Filed: September 3, 1998
    Date of Patent: October 3, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Beate Gutterer
  • Imidazopyridine azolidinones
    Patent number: 6124313
    Abstract: Imidazopyridine-azolidinones are useful for treating or preventing amenable gastro-intestinal ailments.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: September 26, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Gerhard Grundler, Jorg Senn-Bilfinger, Ulrich Thibaut, Georg Rainer
  • Dihydrobenzofurane
    Patent number: 6121274
    Abstract: The invention concerns componuds of formula (I), in which R1, R2, R3 and R4 have the meanings given in the description. The compounds are novel, effective PDE-inhibitors.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: September 19, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventors: Wolf-Rudiger Ulrich, Ulrich Thibaut
  • Substituted 6-phenylphenanthridines
    Patent number: 6121279
    Abstract: The invention relates to compounds of formula (I): wherein R1, R2, R3, R31, R4, R5, R51 and R6 are as defined in the specification. The compounds are phosphodiesterase inhibitors. Also disclosed are pharmaceutical compositions and methods of use of the compounds.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: September 19, 2000
    Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH
    Inventor: Beate Gutterer