Abstract: An in-situ sensor system that is configured to be placed inside of an oxygen mask for a pilot. The sensor system is readily placed in a position over the exhalation valve such that it can capture data from the exhaled air of the pilot. The sensor system has an optical sensor element that can capture data real time and feed the data to a control module that can subsequently be use to generate output data for the pilot and/or ground elements.

Abstract: A solid-state device chip including diodes (generating a higher or lower frequency output through frequency multiplication or mixing of the input frequency) and a novel on-chip diplexing design that allows combination of two or more multiplier or mixer structures operating at different frequency bands within the 50-5000 GHz range within a same chip and/or waveguide. The on-chip diplexing design consists of a single-substrate multiplier chip with two or more multiplying structures each one containing 2 or more Schottky diodes. The diodes in each structure are tuned to one portion of the target frequency band, resulting in the two or more structures working together as a whole as a large broadband multiplier or mixer. Thus, an increase in bandwidth from 10-15% (current state-of-the-art) to at least 40% is achieved. Depending on the target frequencies, each subset of diodes within the chip can be designed to work either as a doubler or a tripler.

Abstract: A detector including a detector membrane comprising a semiconductor sensor and a readout circuit, the detector membrane having a thickness of 100 micrometers or less and a curved surface conformed to a curved focal plane of an optical system imaging electromagnetic radiation onto the curved surface; and a mount attached to a backside of the detector membrane. A maximum of the strain experienced by the detector membrane is reduced by distribution of the strain induced by formation of the curved surface across all of the curved surface of the detector membrane, thereby allowing an increased radius of curvature of the curved surface as compared to without the distribution.

Abstract: The present disclosure describes a cavity accumulating the intensity of the laser beams reflecting within the cavity to build up power while also maintaining a relatively uniform intensity distribution. An apparatus comprising the cavity can be used to build up the power of the electromagnetic radiation for interacting with material, wherein the material does not substantially reflect or absorb the electromagnetic radiation.

Abstract: Systems and methods for embedding a thermal management system in an electric propulsion (EP) system is presented. According to one aspect, one or more oscillating heat pipes (OHPs) are provided within functional elements of the EP system. Each OHP includes channel segments that include a sealed working fluid. The channel segments are joined to form a continuous serpentine channel with a channel path that alternates between hot and cold regions of the EP system. According to another aspect, the functional elements of the EP system are reduced to a single monolithic structure with an embedded OHP. The single monolithic structure may be a single material or a multi material. According to yet another aspect, the functional elements are elements of a magnetic circuit of the EP system, including one or more of a backplate, an outer pole, an inner pole, or a center pole.

Abstract: Provided herein are compositions having a porous, architected three-dimensional geometry that are tiled to achieve increased surface area and/or volume. The tiled compositions include a plurality of tiles having seams where one of the plurality of tiles contacts an adjacent tile. Also provided herein are methods and systems for making the compositions.

Abstract: A system includes, in part, a multitude of RF receivers, a first optical modulator adapted to modulate an optical signal in accordance with a first data received by a first one of RF receivers to generate a first modulated signal, a second optical modulator adapted to modulate the optical signal in accordance with a second data received by a second RF receiver to generate a second modulated signal, and a first optical fiber adapted to carry the first and second modulated signals. The optical modulator may be a photodiode or a Mach-Zehnder modulator.

Abstract: The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for prophylaxis, and methods for diagnosis and treatment of HIV infection.

Abstract: Disclosed herein are trogocytosis based TCR ligand discovery platforms and methods of using the same, trogocytosis based TCR discovery platforms and methods of using the same, and trogocytosis based ligand discovery platforms and methods of using the same. Also disclosed herein are isolated cells, nucleotides, sequences, and sequence databases produced using trogocytosis based discovery platforms.

Abstract: Systems and methods for assessment of lipid membrane-associated molecules are described. Generally, a system can comprise a scaffold with a molecule attached thereon. The scaffold can comprise a plurality of hydrophobic seeds to form a liposome. The molecule attached to the scaffold can integrate into the formed liposome and then be released from the scaffold. The kinetics, dynamics, and interactions of the molecule within the liposome can be detected or monitored.

Abstract: Quantum teleportation is essential for many quantum information technologies, including long-distance quantum networks. Using fiber-coupled devices, including state-of-the-art low-noise superconducting nanowire single-photon detectors and off-the-shelf optics, we achieve conditional quantum teleportation of time-bin qubits at the telecommunication wavelength of 1536.5 nm. We measure teleportation fidelities of ?9% that are consistent with an analytical model of our system, which includes realistic imperfections. To demonstrate the compatibility of our setup with deployed quantum networks, we teleport qubits over 22 km of single-mode fiber while transmitting qubits over an additional 22 km of fiber. Our systems, which are compatible with emerging solid-state quantum devices, provide a realistic foundation for a high-fidelity quantum Internet with practical devices.

Abstract: Systems and methods for a self-powered wireless wearable sensor system include a freestanding triboelectric nanogenerator (FTENG), used as a power source for a wearable sensor. The FTENG includes stator panels and corresponding slider panels with a grating pattern. Movement, such as cardiovascular exercise causes the slider panel(s) to slide across the stator panel(s) inducing a charge and powering a wearable device sufficiently to support data transmission and continuous monitoring. An integrated self-powered wireless wearable sensor system includes a microfluidic sweat sensor patch which may be connected to lower-power wireless sensor circuitry for regulating power efficiently and is powered by the FTENG.

Abstract: A computer-implemented method and system provide the ability to detect an earthquake. Distributed acoustic sensing (DAS) data is obtained. A deep neural network model that picks seismic phase arrival times on the DAS data is acquired. A semi-supervised learning approach is utilized to train the deep neural network model. The semi-supervised learning approach utilizes existing labels from a defined seismic dataset to generate pseudo labels on the DAS data. An earthquake is detected by applying the trained deep neural network model to new DAS data.

Abstract: A method, apparatus, and system provide the ability to act on cyber risks and reduce cyber attacks. System characteristics and system information for a cyber system are gathered. The system characteristics and system information are pre-processed to identify vulnerabilities that are relevant to the cyber system. A system model of a cyber environment is generated for the cyber system. One or more features are converted from cyber threat reports to one or more semantically relevant queries over the system model. The system model is reasoned over to generate one or more answers relevant to the one or more semantically relevant queries. Attack models are executed over the system model to generate actionable intelligence and reduce cyber attacks.

Abstract: Disclosed herein are multi-way oligonucleotide junctions for delivering one or more cargo molecules to a biological target and method of making such junctions. The oligonucleotide junctions are formed by two or more oligonucleotides and are stable outside the cell and easily dissociate inside the cell to release the cargo molecule(s). One or more cargo molecules as well as delivery ligand can be loaded to the junctions for targeted delivery. Also disclosed are nanostructures including one or more junctions attached to each other for delivering two or more cargo molecules.

Abstract: Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) potent VRC01-like (PVL) antibodies targeted to gp120 having an amino acid substitution at a residue in the anti-CD4 binding site PVL antibody that is equivalent to Phe43 in CD4, these antibodies having improved potency and breadth.

Abstract: Among the various aspects described herein is the provision of systems and methods of cross-ray ultrasound tomography. In some embodiments, a cross-ray ultrasound tomography system utilizes an ultrasonic emitter configured to emit one or more ultrasonic waves and an ultrasonic detector array configured to generate one or more radio frequency signals in response to detecting ultrasonic waves. The ultrasonic emitter and the ultrasonic detector array are configured such that the one or more ultrasonic waves are emitted by the ultrasonic emitter at an angle to a focal plane of the ultrasonic detector array.

Abstract: Systems and methods for epitaxy-free thin-film solar cells are described. The thin-film solar cells can be fabricated with low cost epitaxy-free processes. The solar cells have high efficiency and are lightweight. These properties make the solar cells desired for space based solar cell applications.

Abstract: Described herein are compositions and kits comprising recombinant adeno-associated viruses (rAAVs) with tropisms showing increased specificity and efficiency of viral transduction in targeted cell types such as the brain and lung. The rAAV compositions described herein also have tropisms showing decreased specificity and decreased efficiency of viral transduction in an off-target cell type such as the liver. The rAAV compositions described herein encapsidate a transgene, such as a therapeutic nucleic acid. Upon systemic delivery to a subject, the rAAV is capable of increased specificity and increased transduction of the transgene in a target cell-type, as compared to a parental or reference AAV.

Abstract: Systems and methods relate to arranging atoms into 1D and/or 2D arrays; exciting the atoms into Rydberg states and evolving the array of atoms, for example, using laser manipulation techniques and high-fidelity laser systems described herein; and observing the resulting final state. In addition, refinements can be made, such as providing high fidelity and coherent control of the assembled array of atoms. Exemplary problems can be solved using the systems and methods for arrangement and control of atoms.