Abstract: The present invention provides methods for inducing tolerance and/or suppressing an immune response to an antigen by passing a cell suspension containing an anucleate cell through a constriction, wherein the constriction deforms the cell thereby causing a perturbation of the cell such that an antigen and/or tolerogenic factor enters the cell. In some embodiments, the anucleate cell is delivered to an individual and the antigen is delivered to and processed in a tolerogenic environment to induce tolerance and/or suppress an immune response to the antigen.

Abstract: A Rogowski integrator kit, equipped with RJ45 socket, that provides simple installation and protection against Electromagnetic Interference (EMI) and Electrostatic Discharge (ESD). The kit consists of a Rogowski coil that comes with a first RJ45 socket and an electrical integrator that includes a second RJ45 socket. With these features, the Rogowski integrator kit ensures reliable and accurate measurement in a safe and secure manner.

Abstract: A Rogowski integrator kit, equipped with RJ45 socket, that provides simple installation and protection against Electromagnetic Interference (EMI) and Electrostatic Discharge (ESD). The kit consists of a Rogowski coil that comes with a first RJ45 socket and an electrical integrator that includes a second RJ45 socket. With these features, the Rogowski integrator kit ensures reliable and accurate measurement in a safe and secure manner.

Abstract: Systems and methods for determining a user's health/wellness condition. Gait-based biometric data from a user is gathered using a sensor module. The biometric data is transmitted to a data processing module that compares characteristics of the biometric data with previously obtained baseline biometric data from the same user. Differences between the current data and the baseline data indicate changes in the user's condition. Databases containing kinematic chain models for the user are used to obtain more accurate and more specific indications regarding determined changes in the user's condition. A base kinematic chain model is created for the user when the user first uses the system and current kinematic chain models are generated for each biometric data set gathered. Characteristics of the base and the current kinematic chain models are compared to determine changes in the user's condition.

Abstract: Disclosed are novel fused mescaline derivative compounds, notably C1-substituted isopropylamine fused heterocyclic mescaline derivatives, including C1-substituted isopropylamine fused dioxolane and fused dioxane mescaline derivatives, and pharmaceutical and recreational drug formulations containing the same. Methods of making and using these compounds are also disclosed.

Abstract: In some implementations, a machine learning model (e.g., a knowledge processing system) can apply a reasoning technique to knowledge representations associated with cells (e.g., using a genetic algorithm) and predict a clinical outcome (e.g., for a patient). In some implementations, a method includes producing a cell population. Gene expression data for the cell population can be received. The gene expression data can be analyzed to identify a set of gene signatures. The set of gene signatures can be provided as an input to a machine learning classifier. A predicted clinical outcome can be generated.

Abstract: Disclosed are novel hydroxylated psilocybin derivative compounds and pharmaceutical and recreational drug formulations containing the same. The compounds may be produced synthetically or biosynthetically.

Abstract: A landing gear system includes a landing gear assembly coupled to a body of a vehicle and configured for reciprocating motion between a retracted position and an extended position. A fail-secure uplock assembly is reciprocal between a locked state and an unlocked state. A first electromagnet and a first permanent magnet are mounted to the body, and a second electromagnet and a second permanent magnet are mounted to a component of the landing gear assembly. The first and second electromagnets generate magnetic fields with reversible polarities. When the landing gear assembly is in the retracted position, the first permanent magnet is attracted to the second permanent magnet. The first electromagnet is attracted to the second electromagnet when the uplock assembly is in the locked state and is repelled by the second electromagnet when the uplock assembly is in the unlocked state.

Abstract: A landing gear system for a vehicle includes a landing gear configured for reciprocating motion between a stowed position and a deployed position. The landing gear has a linkage with a first link rotatably coupled to a second link. The linkage reciprocates between folded and extended states when the landing gear reciprocates between the stowed and deployed positions, respectively. A fail-secure downlock includes first and second electromagnets fixedly positioned relative to the first and second links, respectively. The first electromagnet is proximate to the second electromagnet when the landing gear is in the stowed position. The first electromagnet is attracted to the second electromagnet when the downlock is in the locked state. The first electromagnet is repelled by the second electromagnet when the downlock is in the unlocked state.

Abstract: The present invention relates to an electricity meter with a unique structure to prevent tampering and damage to the nameplate. The meter comprises a drawer-like structure with an opening, a nameplate positioned within the drawer-like structure, and a cover fixed to the drawer-like structure over the opening. The cover is designed to protect the nameplate from any external factors that could potentially damage or tamper with it. This innovative design ensures the accuracy and reliability of the electricity meter, preventing any interference with the nameplate. The design can be adapted to various types of electricity meters, making it an essential feature for maintaining the integrity of the meter.

Abstract: Electric motors and methods of controlling electric motors are described herein. The electric motors include a mobile component having at least one permanent magnet coupled thereto and a stator spaced apart from the mobile component. The stator includes at least one stator pole having a ferromagnetic core and a coil wrapped around the ferromagnetic core. The ferromagnetic core is naturally attracted to the at least one permanent magnet. The motors also include a magnetic position control system configured to monitor a position of the at least one permanent magnet relative to the stator and controllably deliver an electric pulse to the coil of each stator pole to generate a repulsive magnetic flux on the ferromagnetic core to cancel an attraction force between the ferromagnetic core and the at least one permanent magnet to control movement of the mobile component.

Abstract: Systems and method of calibrating a range measurement system for a vehicle mounted on a guideway are disclosed. In some embodiments, a method includes: measuring a first time of transmission (TOT) between a first internal component of an on-board range measurement device and a second internal component of a wayside range measurement device. The first TOT is compared with a first pre-determined time. A health of the range measurement system is determined based on a difference between the first TOT and the first pre-determined time.

Abstract: The present invention relates to a system for stimulating alertness in a subject within an environment exposed to an ambient light having a fluctuating ambient light illuminance. The system comprises an optical generator with a light source configured to generate a stimulating light having a stimulating light irradiance; and a driver coupled to the light source for controlling the stimulating light irradiance; an ambient light sensor configured to monitor the ambient light illuminance in real-time; and a controller operatively coupled to the optical generator and to the ambient light sensor to control the stimulating light irradiance in response to the ambient light illuminance monitored by the ambient light sensor, the controlling comprising capping the stimulating light irradiance to a maximal irradiance value based on the monitored ambient light illuminance. The present invention also relates to a method for stimulating alertness in a subject.

Abstract: Systems and methods relating to the replacement or removal of sensitive data in images of documents. An initial image of a document with sensitive data is received at an execution module and changes are made based on the execution module's training. The changes include replacing or effectively removing the sensitive data from the image of the document. The resulting sanitized image is then sent to a user for validation of the changes. The feedback from the user is then used in training the execution module to refine its behaviour when applying changes to other initial images of documents. To train the execution module, training data sets of document images with sensitive data manually tagged by users are used. The execution module thus learns to identify sensitive data and its submodules replace that sensitive data with suitable replacement data. The feedback from the user works to improve the resulting sanitized images from the execution module.

Abstract: Systems, methods, and devices for verification of an immunization status of an individual and for secure data portability are provided. A system for verifying an immunization status of an individual includes a verification device, a vault computing device, and an immunization record database server. The verification device includes a web terminal configured to send an immunization status request including identifying data about the individual. The vault computing device receives the immunization status request and generates and sends an immunization record request including an insurance plan number corresponding to the individual. The immunization record database server has access to an immunization record database and retrieves immunization record data from the immunization record database using the insurance plan number and sends the immunization record data to the vault computing device.

Abstract: An apparatus and a process for the production at high capacity of high purity powders from a wire using a combination of plasma torches and induction heating are disclosed. The process has good productivity by providing a preheating system. A mechanism is included in the apparatus, which allows adjusting the position of the plasma torches and their angle of attack with respect to the wire, permitting to control the particle size distribution.

Abstract: An upper for an article of footwear includes a three-dimensional engineered textile having an inner section, an outer section, and an intermediate section disposed between the inner section and the outer section. The intermediate section is attached to the inner section on one side and the outer section on an opposite side. The intermediate section extends through at least a forefoot region of the upper. In the forefoot region, the intermediate section includes a plurality of curving portions arranged adjacent to each other such that each curving portion of the plurality of curving portions is spaced apart from neighboring curving portions by one or more gaps. Air is configured to flow from an interior of the upper to an exterior of the upper through the one or more gaps between neighboring curving portions of the plurality of curving portions in the forefoot region of the upper.

Abstract: An upper for an article of footwear includes a three-dimensional engineered textile having an inner section, an outer section, and an intermediate section disposed between the inner section and the outer section. The intermediate section is attached to the inner section on one side and the outer section on an opposite side. The intermediate section extends through at least a forefoot region of the upper. In the forefoot region, the intermediate section includes a plurality of curving portions arranged adjacent to each other such that each curving portion of the plurality of curving portions is spaced apart from neighboring curving portions by one or more gaps. Air is configured to flow from an interior of the upper to an exterior of the upper through the one or more gaps between neighboring curving portions of the plurality of curving portions in the forefoot region of the upper.