Abstract: A circuit board connector is disclosed that has isolator ribs between contact tails, and slots in the edge of a circuit board between circuit pads that communicate with the ribs to avoid pad-to-pad current leakage and high-voltage breakdown. The slots may be between individual circuit board fingers that each include one of the conductor pads.

Abstract: A method can include providing (302) at least one parameter to control a therapy that is applied to at least one internal anatomical structure of a patient. Electrical data can be obtained from the patient (304), including electrical data acquired via a plurality of sensors during each of a plurality of iterations of the therapy. The electrical data can be analyzed (306) for a respective value of the at least one parameter of the therapy at each of the plurality of iterations of the applied therapy to compute an indication of at least one function of the at least one internal anatomical structure of the patient at each respective iteration of the applied therapy. The computed indication can be stored in memory (308). At least one parameter of the therapy can be adjusted (310) for delivery in a subsequent one of the plurality of iterations based on the indication of the at least one function.

Abstract: Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.

Abstract: A method for visualization of electrophysiology information can include storing electroanatomic data in memory, the electroanatomic data representing electrical activity on an anatomic region within a patient's body over a time period. An interval within the time period is selected in response to a user selection. A visual representation of physiological information for the user selected interval can be generated by applying at least one analysis method to the electroanatomic data. The visual representation can spatially represented on a graphical representation of the anatomic region within the patient's body.

Abstract: A system (10) can localize an object in a patient's body. The system (10) can include a pulse generator (18 or 30) configured to provide a localization signal to at least one electrode that is fixed to the object in the patient's body. A sensor array (22) can be configured to detect an electrical field produced in response to the localization signal and provide respective sensor signals. A map generator (42) can be configured to reconstruct electrical signals based on the respective sensor signals and geometry data representing a geometric relationship between patient anatomy and the sensor array. A location calculator (50) can determine a location where the localization signal was applied based on the reconstructed electrical signals.

Abstract: A map generator can be programmed to generate a multi-parameter graphical map by encoding at least two different physiological parameters for a geometric surface, corresponding to tissue of a patient, using different color components of a multi-dimensional color model such that each of the different physiological parameters is encoded by at least one of the different color components.

Abstract: A method can determine one or more origins of focal activation. The method can include computing phase for the electrical signals at a plurality of nodes distributed across a geometric surface based on the electrical data across time. The method can determine whether or not a given candidate node of the plurality of nodes is a focal point based on the analyzing the computed phase and magnitude of the given candidate node. A graphical map can be generated to visualize focal points detected on the geometric surface.

Abstract: A method can include storing a plurality of data sets including values computed for each of a plurality of points for a given spatial region of tissue, the values in each of the data sets characterizing electrical information for each respective point of the plurality of points for a different time interval. The method can also include combining the values computed for each of a plurality of points in a first interval, corresponding to a first map, with the values for computed for each of the respective plurality of points in another interval and to normalize the combined values relative to a common scale. The method can also include generating a composite map for the given spatial region based on the combined values that are normalized.

Abstract: A method can include storing input electrical signal data representing at least a given electrophysiological signal acquired from a patient. A non-local mean filter can be applied to the given electrophysiological signal, the non-local mean filter including a spatial filter component and an intensity filter component. The method can also include controlling parameters to establish weighting of each of the spatial filter component and the intensity filter component in response to a control input. Filtered signal data can be stored based on the applying and the controlling.

Abstract: A method to calculate and visualize dynamic wave front propagation of electrical signals on a geometric surface is described. Wave front locations are identified on the geometric surface between each identified pair of adjacent nodes on the geometric surface. A graphical map can be generated to represent the identified wave front locations on at least a portion of the geometric surface.

Abstract: Uniquely positioned slots are provided in the receptacle and uniquely positioned bosses are provided in the plug of a connector pair. These features are designed to prevent the plug from being inserted midspan and damaging the exposed contacts of the receptacle. The bosses may be located near outside corners of the plug, and may protrude sufficiently from the face of the plug to prevent the corners of the plug from being inserted into the receptacle, except when the bosses are aligned with the boss-receiving slots in the receptacle.

Abstract: A device includes an electrical connector coupled to the end of a flex circuit. The connector includes interior ribs that engage slots in the flex circuit, with the ribs and slots separating adjacent contact pads on the flex circuit. The contact pads are exposed portions of conductive traces on the flex circuit. Other portions of the conductive traces may be covered by a dielectric material, such as a non-conductive ink. The ribs provide an increased isolation path between the contact pads.

Abstract: A method can include providing (302) at least one parameter to control a therapy that is applied to at least one internal anatomical structure of a patient. Electrical data can be obtained from the patient (304), including electrical data acquired via a plurality of sensors during each of a plurality of iterations of the therapy. The electrical data can be analyzed (306) for a respective value of the at least one parameter of the therapy at each of the plurality of iterations of the applied therapy to compute an indication of at least one function of the at least one internal anatomical structure of the patient at each respective iteration of the applied therapy. The computed indication can be stored in memory (308). At least one parameter of the therapy can be adjusted (310) for delivery in a subsequent one of the plurality of iterations based on the indication of the at least one function.

Abstract: A linear connector contact array is presented with focus on the tails of the contacts that are connected to individual wires. A wire management comb made from dielectric material positions each wire over its contact's tail. The wire is attached to the tail by electrically welding the wire to the tail without removing the insulating material. This is accomplished with a heated welding electrode that melts through the insulator material until electrical contact is made with the wire. A non-heated electrode is beneath the tail to complete this circuit. The wire management comb has deep channels which form insulating ribs between adjacent wires. The weld sites are staggered, and exposed ends of the contact tails are held short of the end of the management comb.

Abstract: Systems and methods can be utilized to visualize physiological data relative to a surface region (e.g., an organ) of a patient. A computer-implemented method can include storing electroanatomic data in memory representing electrical activity for a predetermined surface region of the patient and providing an interactive graphical representation of the predetermined surface region of the patient. A user input is received to define location data corresponding to a user-selected location for at least one virtual electrode on the graphical representation of the predetermined surface region of the patient. A visual representation of physiological data for the predetermined surface region of the patient is generated based on the location data and the electroanatomic data.

Abstract: A non-transitory computer-readable medium can have instructions executable by a processor. The instructions can include an electrogram reconstruction method to generate reconstructed electrogram signals for each of a multitude of points residing on or near a predetermined cardiac envelope based on geometry data and non-invasively measured body surface electrical signals. The instructions can include a phase calculator to compute phase signals for the multitude of points based on the reconstructed electrogram signals and a visualization engine to generate an output based on the computed phase signals.

Abstract: Systems and methods can be used to determine activation information for points along a surface or selected region of interest. In one example, a computer-readable medium having computer-executable instructions for performing a method that includes computing a local activation vector based on relative timing among electrical signals corresponding to neighboring points of a plurality of points on a surface envelope. An activation time can be computed for each of the plurality of points as a function of corresponding local activation vectors.

Abstract: A computer-implemented method can include determining an amplitude for each of a plurality of input channels, corresponding to respective nodes. A measure of similarity can be computed between the input channel of each node and the input channel of its neighboring nodes. The method can also include comparing an amplitude for each node relative to other nodes to determine temporary bad channels. For each of the temporary bad channels, a measure of similarity can be computed between the input channel of each node and the input channel of its neighboring nodes. Channel integrity can then be identified based on the computed measures of similarity.

Abstract: A sensor array system (10, 30) can include a substrate layer (12, 14) that includes a stretchable and conformable material that is configured to allow spaced apart and interconnected portions thereof to stretch and conform commensurate with movement of the substrate layer (12, 14), such as when attached to a patient's body. A plurality of electrodes (16) are disposed on a contact surface of the substrate layer (12, 14). Electrically conductive paths are also disposed on the substrate layer (14) and extending from each of the electrodes to which it is connected and terminating in an end thereof. The substrate layer may itself include more than one layer, such as including a flexible substrate layer (12) that is affixed to a stretchable material layer (14).