Patents Assigned to Cassella
  • Alkenyl-phosphonic and -phosphinic esters, process for their preparation, their use and hydrogels prepared using them
    Patent number: 5068298
    Abstract: The present invention relates to compounds of the general formula I ##STR1## in which R.sup.1, R.sup.1', R.sup.2, A and n are as defined in the description, a process for their preparation, their use and also hydrogels prepared using them.
    Type: Grant
    Filed: June 25, 1990
    Date of Patent: November 26, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Friedrich Engelhardt, Ulrich Riegel, Joachim Gersdorf, Hans-Jerg Kleiner
  • Alkenylphosphonic and --phosphinic acid esters, process for their preparation, hydrogels produced using them, and their use
    Patent number: 5066745
    Abstract: Alkenylphosphonic and -phosphinic acid esters of 1,1,1-tris(hydroxymethyl)alkanes and of 2,2-bis-hydroxymethyl-1,3-propanediol are useful as cross-linking agents in polymeric hydrogels.
    Type: Grant
    Filed: May 29, 1990
    Date of Patent: November 19, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Friedrich Engelhardt, Ulrich Riegel, Joachim Gersdorf, Hans-Jerg Kleiner
  • Pyrrolealdehydes, their preparation and their use
    Patent number: 5043348
    Abstract: Pyrrolealdehydes of the formula I ##STR1## wherein R and R.sup.1 independently of one another denote hydrogen or alkyl with 1 to 4 C atoms, R.sup.2 denotes alkyl, which is substituted by acylamino of the formula II ##STR2## wherein X stands for an oxygen or sulphur atom and R.sup.3 denotes hydrogen, optionally substituted alkyl or alkylamino, cycloalkyl with 5 to 7 C atoms, optionally substituted phenyl, an amino group or an optionally substituted phenylamio group, and pharmaceutically acceptable acid addition salts thereof, and wherein R.sup.3 cannot represent hydrogen if R and R.sup.1 denote hydrogen and the pyrrole ring is formylated in the 3-position, their preparation and their use.
    Type: Grant
    Filed: February 26, 1990
    Date of Patent: August 27, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Gerhard Zoller, Rudi Beyerle, Ursula Schindler
  • Hydrophilic, swellable graft copolymers, their preparation and use
    Patent number: 5041496
    Abstract: The present invention relates to hydrophilic, swellable graft copolymers composed, in random distribution, of 0.5 to 20% by weight of radicals of the general formula I ##STR1## of 79 to 99% by weight of radicals containing an acidic group, of the general formula II ##STR2## and of 0.1 to 2% by weight of radicals of a crosslinking agent which are derived from monomers having at least two olefinically unsaturated double bonds, and the radicals X, Z, m, n, z and also R.sup.1 to R.sup.4 are defined as given in the description, a process for the preparation of these graft copolymers and also their use as absorbents for water and aqueous solutions.
    Type: Grant
    Filed: March 19, 1990
    Date of Patent: August 20, 1991
    Assignee: Cassella AG
    Inventors: Friedrich Engelhardt, Ulrich Riegel, Jurgen Kuhlwein
  • Process for the preparation of 2-substituted 1-(acylaminoalkyl)-2-imidazolines
    Patent number: 5041553
    Abstract: In the process for the preparation of 2-substituted 1-(acylaminoalkyl)-2-imidazolines of the general formula I ##STR1## wherein R denotes an alkylene radical and R.sup.1 denotes a fatty acid radical, for example, a fatty acid and a dialkylenetriamine are reacted in a molar ratio of (1.9 to 2.0): 1 in such a way that the dialkylenetriamine is initially introduced hot under an inert gas atmosphere and the fatty acid is metered in hot and the amido amine formation is subsequently completed by heating to temperatures from 140.degree. to 190.degree. C. and the cyclization to the compound of the formula I is subsequently carried out at an under-pressure of at least 50 mbar.
    Type: Grant
    Filed: September 17, 1990
    Date of Patent: August 20, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl-Heinz Keil, Georg-Wolfgang Eckardt, Herbert Wirtz, Helmut Berenbold, Werner Wellbrock, Horst Frohlich
  • .beta.-modification of 1-(2,4-dinitro-6-chloro-phenylazo)-2-propionylamino-4-N-ethylamino-5-(2- methoxy-ethoxy)benzene, its preparation and its use
    Patent number: 5037962
    Abstract: The .beta.-modification, which is stable under dyeing conditions, of the dyestuff of the formula ##STR1## is prepared by heating the .alpha.-modification, which is unstable under dyeing conditions, at temperatures of 60.degree. to 180.degree. C. and the .beta.-modification is useful in printing and dyeing fiber materials of cellulose esters, synthetic linear polyesters or mixed fabrics of the polyester fiber material with wool or viscose staple.
    Type: Grant
    Filed: August 21, 1989
    Date of Patent: August 6, 1991
    Assignee: Cassella AG
    Inventors: Hubert Kruse, Ulrich Buhler, Konrad Opitz, Willi Steckelberg
  • Thienylacetic acid derivatives, process for the preparation thereof, the use thereof, and pharmaceuticals containing these and the preparation thereof
    Patent number: 5015659
    Abstract: The present invention relates to thienylacetic acid derivatives of the general formula I ##STR1## in which X denotes --O-- or --NH--;R.sup.1 denotes hydrogen, the group --CH.sub.2 --CO--R.sup.3 or the group --CO--CH.sub.2 --NH.sub.2 ;R.sup.2 denotes hydrogen, (C.sub.1 -C.sub.4)-alkyl or the radical R.sup.1 andR.sup.3 denotes (C.sub.1 -C.sub.4)-alkoxy, hydroxyl or amino, it not being possible for both R.sup.1 and R.sup.2 to represent hydrogen when X denotes O,as well as the pharmaceutically tolerated salts thereof, process for the preparation thereof, the use thereof, and pharmaceuticals containing these and the preparation thereof.
    Type: Grant
    Filed: March 14, 1990
    Date of Patent: May 14, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Ursula Schindler, Bernd Jablonka, Jeffery Troke
  • Hydrophilic swellable graft copolymers, their preparation and use
    Patent number: 5011892
    Abstract: The present invention relates to hydrophilic, swellable graft copolymers composed, in random distribution, of 0.5 to 20% by weight of radicals of the general formula I ##STR1## 79 to 99% by weight of radicals containing an acidic group, of the general formula II ##STR2## and 0.1 to 2% by weight of crosslinking structures which are derived from monomers having at least two olefinically unsaturated double bonds, where the radicals X, Y, R.sup.1 to R.sup.4 and n have the meanings given in claim 1, and which are used as absorbents for water and aqueous solutions.
    Type: Grant
    Filed: March 26, 1990
    Date of Patent: April 30, 1991
    Assignee: Cassella AG
    Inventors: Friedrich Engelhardt, Ulrich Riegel
  • Substituted 3-aminosydnonimines, processes for their preparation and their use
    Patent number: 5006540
    Abstract: Substituted 3-aminosydnonimines of the formula I ##STR1## and their pharmacologically acceptable acid addition salts, wherein R.sup.1 denotes, for example, alkyl having 1 to 8 C atoms, R.sup.2 denotes hydrogen or the radical --COR.sup.3 and R.sup.3 denotes, for example, an aliphatic radical having 1 to 4 C atoms, are prepared, for example, by cyclization of a compound of the formula II ##STR2## and if appropriate subsequent acylation and have useful pharmacological properties.
    Type: Grant
    Filed: October 17, 1989
    Date of Patent: April 9, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Melitta Just, Helmut Bohn, Jorg Ostrowski
  • Thienylpiperazines, the use thereof and pharmaceuticals containing these
    Patent number: 4987134
    Abstract: The present invention relates to thienylpiperazines of the general formula I ##STR1## in which R.sup.1 denotes hydrogen or double-bonded oxygen and R.sup.2 denotes hydrogen or double-bonded oxygen, with R.sup.1 and R.sup.2 not both having the same meaning, as well as the pharmaceutically tolerated salts thereof, process for the preparation thereof, the use thereof, and pharmaceuticals containing these and the preparation thereof.
    Type: Grant
    Filed: March 16, 1990
    Date of Patent: January 22, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Ursula Schindler, Bernd Jablonka, Jeffery Troke
  • Mixtures of monoazo dyes containing halogen and cyano substituents
    Patent number: 4985043
    Abstract: Mixtures of monoazo dyes suitable for dyeing and printing hydrophobic fiber materials and mixtures thereof with natural fibers contain one or more dyes of the formula I ##STR1## and one or more dyes of the formula II ##STR2## in which Hal denotes bromo or chloro; R.sup.1 and R.sup.2, independently of one another, denote methyl or ethyl; R.sup.3, R.sup.4, R.sup.5 and R.sup.6, independently of one another, denote linear alkyl having 1 to 4 carbon atoms or alkenyl having 3 or 4 carbon atoms; and R denotes methyl, acetylamino, propionylamino, i-butyrylamino, or n-butyrylamino.
    Type: Grant
    Filed: March 15, 1989
    Date of Patent: January 15, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Manfred Hahnke, Reinhard Kuhn, Margarete Boos
  • Mixtures of mon-azo dyestuffs for dyeing and printing hydrophobic synthetic fiber materials
    Patent number: 4985045
    Abstract: A monoazo dyestuff composition comprising at least two different individual compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently of each other, are linear or branched alkyl having 1 to 4 carbon atoms and R is linear or branched alkyl having 1 to 5 carbon atoms, and where said individual compounds differ from each other in at least the R moiety, has improved dyeing properties compared with the individual dyestuffs when used to dye or print hydrophobic fiber materials.
    Type: Grant
    Filed: October 30, 1989
    Date of Patent: January 15, 1991
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Klaus Hofmann
  • Polybase from amino amido carboxylic acid, polyamine and difunctional alkylating agent
    Patent number: 4977239
    Abstract: A water-soluble organic polybase which is useful for the cationization of asbestos-free, cellulose fiber filter media is prepared by reacting a mixture of a compound of the formulaR.sup.2 --CO--R.sup.1 --COOHand a polyalkyleneimine with a difunctional alkylating agent, wherein R.sup.1 is a single bond or alkylene having 1 to 10 carbon atoms and R.sup.2 is inter alia a moiety of the formulaH.sub.2 N--(CH.sub.2).sub.u --NH--(CH.sub.2).sub.u --NH).sub.wwherein u is the number 2, 3, 4 or 5 and w is the number 0, 1, 2 or 3.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: December 11, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Walter Kamutzki, Karl-Heinz Keil
  • Water-soluble aminonaphthol disazo dyestuffs, their preparation and their use
    Patent number: 4973672
    Abstract: Coloring natural or synthetic fiber material containing hydroxyls or nitrogen is achieved by printing or dyeing the fiber material with a water-soluble disazo dyestuff of the formula ##STR1## wherein R.sup.1 is alkyl, alkoxy or alkoxyethoxy, each having 3-6 carbon atoms, B.sup.1 is the radical of a 1-amino-8-hydroxynaphthalene monosulphonic or disulphonic acid and B.sup.2 is the same as B.sup.1 or another napthyl moiety.
    Type: Grant
    Filed: March 27, 1989
    Date of Patent: November 27, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Wolfgang Bauer, Klaus Hunger
  • Pyrrole derivatives, their preparation and their use as pharmaceutical active compounds
    Patent number: 4966901
    Abstract: Pyrrole derivatives of the general formula I ##STR1## wherein R denotes alkyl which is substituted by --NH.sub.2 or acylamino, R.sup.1 and R.sup.2 independently of one another denote hydrogen or alkyl having 1 to 4 carbon atoms, R.sup.3 denotes hydrogen, alkyl having 1 to 4 carbon atoms or a carboxylic acid grouping, R.sup.
    Type: Grant
    Filed: May 23, 1989
    Date of Patent: October 30, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Gerhard Zoller, Rudi Beyerle, Ursula Schindler
  • Alkenylphosphonic and -phosphinic acid esters, process for their preparation, hydrogels produced using them, and their use
    Patent number: 4959441
    Abstract: Alkenylphosphonic and -phosphinic acid esters of 1,1,1-tris(hydroxymethyl)alkanes and of 2,2-bis-hydroxymethyl-1,3-propanediol are useful as cross-linking agents in polymeric hydrogels.
    Type: Grant
    Filed: May 8, 1989
    Date of Patent: September 25, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Friedrich Engelhardt, Ulrich Riegel, Joachim Gersdorf, Hans-Jerg Kleiner
  • Water-insoluble monoazo dyes, their preparation and use, and mixtures of these monoazo dyes
    Patent number: 4950305
    Abstract: Hydrophobic textile materials can be dyed or printed with one or more monoazo dyes of the formula ##STR1## in which R.sup.1 is fluoro, chloro or bromo;R.sup.2 is hydrogen or chloro; andR.sup.3 is allyl, alkyl having 1 to 4 carbon atoms, alkoxyalkyl having 2 to 4 carbon atoms in the alkyl portion and 1 to 4 carbon atoms in the alkoxy portion or cyanoalkyl having 2 to 4 carbon atoms.
    Type: Grant
    Filed: August 7, 1989
    Date of Patent: August 21, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Ulrich Buhler, Margareta Boos, Reinhard Kuhn
  • N-substituted N-nitrosoaminoacetonitriles, process for their preparation and their use
    Patent number: 4937241
    Abstract: Pharmacologically useful N-substituted-N-nitrosoaminoacetonitriles of the general formula I ##STR1## wherein A denotes the radical --CH.sub.2 --, --O--, --S(O.sub.n)--, --N(R.sup.2)-- or a direct bond,R.sup.1 and R.sup.
    Type: Grant
    Filed: December 27, 1988
    Date of Patent: June 26, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle, Helmut Bohn
  • Process for dyeing and printing synthetic fibers with mixtures of monoazo dyestuffs
    Patent number: 4937325
    Abstract: A monoazo dyestuff composition comprising at least two different individual compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently of each other, are linear or branched alkyl having 1 to 4 carbon atoms and R is linear or branched alkyl having 1 to 5 carbon atoms, and where said individual compounds differ from each other in at least the R moiety. The monoazo dyestuff mixtures are used for the dyeing and printing of hydrophobic fibers such as high molecular weight polyesters of their mixtures with natural fiber material.
    Type: Grant
    Filed: December 12, 1988
    Date of Patent: June 26, 1990
    Assignees: Cassella Aktiengesellschaft, Tokico Ltd.
    Inventors: Ulrich Buhler, Klaus Hofmann, Hiroshi Mitsuhashi, Harutsugu Ushiota, Akiharu Odagiri, Gen Kano, Susumu Sakamoto
  • Substituted 3-aminosydnonimines, processes for their preparation and their use
    Patent number: 4937244
    Abstract: Substituted 3-aminosydnonimines of the formula I ##STR1## and their pharmacologically acceptable acid addition salts wherein A denotes, for example, --CH.sub.2 --,R.sup.1 denotes hydrogen or the radical --COR.sup.7,R.sup.2, R.sup.3, R.sup.4 and R.sup.5 denote alkyl with 1 to 4 C atoms andR.sup.7 denotes, for example, an aliphatic radical and 1 to 4 C atoms, are prepared by cyclization of a compound of the formula II ##STR2## and if appropriate subsequent acylation and have useful pharmacological properties. The invention includes pharmaceutical preparations containing the present compounds, and the use thereof for treating patients having cardiovascular ailments.
    Type: Grant
    Filed: August 3, 1988
    Date of Patent: June 26, 1990
    Assignee: Cassella Aktiengesellschaft
    Inventors: Karl Schonafinger, Rudi Beyerle