Abstract: The microbial nucleic acid detection method comprises the steps of: preparing a sample mixture by: mixing a probe solution, being a gold nanoparticle probe solution in which DNA that binds specifically to a target nucleic acid is modified with gold nanoparticles, with an extract obtained by applying a nucleic acid extraction treatment to a sample; and adding at least sodium chloride and applying heat thereto; acquiring an absorption spectrum of the probe solution; acquiring an absorption spectrum of a blank solution, being a sample-free solution obtained by adding sodium chloride to the probe solution and applying heat thereto; acquiring an absorption spectrum of the sample mixture; and performing calculations to estimate the concentration of the target nucleic acid in the sample based on the absorption spectra of the probe solution, the blank solution, and the sample mixture.
Type:
Application
Filed:
April 18, 2024
Publication date:
September 24, 2026
Applicants:
NATIONAL UNIV CORPORATION HOKKAIDO UNIV, CELLSPECT CO., LTD.
Abstract: [Problem] To provide a method for acquisition of data able to serve as an index for determining the likelihood that an ovarian endometriosis cyst is cancerous. [Solution] This data acquisition method for determining the likelihood that an ovarian endometriosis cyst is cancerous includes an iron concentration measurement step for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst. This diagnostic device for diagnosing the likelihood that an ovarian endometriosis cyst is cancerous is provided, at a minimum, with an iron concentration measurement unit for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst.
Abstract: [Problem] To provide a method for acquisition of data able to serve as an index for determining the likelihood that an ovarian endometriosis cyst is cancerous. [Solution] This data acquisition method for determining the likelihood that an ovarian endometriosis cyst is cancerous includes an iron concentration measurement step for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst. This diagnostic device for diagnosing the likelihood that an ovarian endometriosis cyst is cancerous is provided, at a minimum, with an iron concentration measurement unit for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst.
Abstract: [Problem] To provide a method for acquisition of data able to serve as an index for determining the likelihood that an ovarian endometriosis cyst is cancerous. Solution This data acquisition method for determining the likelihood that an ovarian endometriosis cyst is cancerous includes an iron concentration measurement step for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst. This diagnostic device for diagnosing the likelihood that an ovarian endometriosis cyst is cancerous is provided, at a minimum, with an iron concentration measurement unit for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst.
Abstract: An Fe(II) ion detection agent, and related method, capable of fluorescently detecting Fe(II) ions quickly with high sensitivity is disclosed. The Fe(II) ion detection agent can be a compound represented by formula (I) (fluorescence probe): wherein R1 and R2 represent lower alkyl; R3 and R4 represent hydrogen; R5 represents hydrogen, hydroxyl, or a group represented by formula (A): —NR51R52 wherein R51 and R52 represent lower alkyl; R6 and R7 represent hydrogen; ring A represents an aromatic ring; V represents O or SiR10R11 wherein R10 and R11 are the same or different and represent, hydrogen or lower alkyl; W represents CH2, CO; Z represents O; m and n are the same or different and represent 0 or 1. The agent can be combined with a compound having at least three coordinating positions.
Abstract: [Problem] To provide a method for acquisition of data able to serve as an index for determining the likelihood that an ovarian endometriosis cyst is cancerous. Solution This data acquisition method for determining the likelihood that an ovarian endometriosis cyst is cancerous includes an iron concentration measurement step for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst. This diagnostic device for diagnosing the likelihood that an ovarian endometriosis cyst is cancerous is provided, at a minimum, with an iron concentration measurement unit for measuring the iron concentration in the cystic fluid of the ovarian endometriosis cyst.