Patents Assigned to CENTRE NATIONAL DE LA
  • Method for preparing oligonucleotides
    Publication number: 20100069623
    Abstract: A solution phase synthesis method for preparing an oligonucleotide, wherein at least some of the reagents are solid supported. The method suitable for large-scale synthesis comprises coupling a protected compound with a nucleotide derivative having a protection group in the presence of a solid supported activator to give an elongated oligonucleotide with a P(III)-internucleotide bond; optionally processing the elongated oligonucleotide by capping by reaction with a solid supported capping agent and/or by oxidizing or sulfurizing by reaction of the oligonucleotide with a solid supported oxidizing or sulfurization reagent; and removing the protection group. The coupling may include reacting a 3?-protected compound of formula: with a nucleotide derivative having a 5?-protection group, or reacting a 5?-protected compound of formula with a nucleotide derivative having a 3?-protection group.
    Type: Application
    Filed: April 3, 2009
    Publication date: March 18, 2010
    Applicants: GIRINDUS AG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITY OF MONTPELLIER II
    Inventors: Ilaria Adamo, Cècile Dueymes, Andreas Schönberger, Jean-Louis Imbach, Albert Meyer, Francois Morvan, Francoise Debart, Jean-Jacques Vasseur, Meinolf Lange, Fritz Link
  • METAL-POLYMER COORDINATION COMPLEX INCORPORATING PHOSPHORUS ATOMS AND APPLICATIONS USING SUCH A COMPLEX
    Publication number: 20100068143
    Abstract: The invention relates to a compound comprising at least one polymeric chain incorporating phosphorus atoms and consisting, in all or in part, of identical or different repeated units, each of said units being represented by the following formula: wherein X3 represents —[Si(O2)]—; or —O—[Si(R1R2)O]— with R1 and R2 being, independently of each other, a C1-C30 alkyl or alkoxy group, a C5-C30 aryl group; or a mono- or polyorganosilicate derived radical; or —N(R3)— with R3 being —H, a C1-C30 alkyl group or a C5-C30 aryl group, optionally substituted with —OH or —NH2, or at least one unit of general formula (I), and ?X4 represents an electron pair, ?O, ?S, ?NR4 with R4 representing a C1-C30 alkyl group or a C5-C30 aryl group, ?Se or ?Te, and its use for complexing metal atoms.
    Type: Application
    Filed: March 17, 2009
    Publication date: March 18, 2010
    Applicants: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Steven VAN ZUTPHEN, Nicolas MEZAILLES, Pascal LE FLOCH
  • DEVICE WITH PLANE JETS FOR REDUCING THE NOISE GENERATED BY A JET AIRCRAFT
    Publication number: 20100065680
    Abstract: The invention relates to an aircraft engine having a longitudinal axis (XX?), comprising a wall (30) surrounding a gas stream that is ejected at a downstream end (30a) of the wall along the longitudinal axis, characterized in that a plurality of conduits (60, 62, 64, 66, 68, 70, 72, 74) distributed at the periphery of the downstream end of the wall are each capable of ejecting, via an outlet orifice (60c), a fluid jet (76) in the form of a sheet, in such a way that the jets thus ejected each form a fluid perturbation around the ejected gas stream.
    Type: Application
    Filed: March 31, 2009
    Publication date: March 18, 2010
    Applicants: Airbus France, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ( CNRS ), UNIVERSITE DE POITIERS
    Inventors: Jerome HUBER, Jean-Paul BONNET, Joel DELVILLE, Peter JORDAN, Francois STREKOWSKI
  • METHOD OF CHARACTERISING THE ANISOTROPY OF A SCATTERING MEDIUM AND DEVICE FOR IMPLEMENTING SUCH A METHOD
    Publication number: 20100067006
    Abstract: The invention relates to a method of characterizing a scattering medium. According to the invention, the processing on the electromagnetic radiation scattered by the scattering medium is carried out for an unpolarized signal. In this way, only the anisotrophic incoherent transport of radiation induced by the scattering medium is obtained in the characterization according to the invention. According to the invention, the data representative of the angular variation of the first image representing the unpolarized scattered radiation is representative of the purely isotrophic part of the scattering. Having obtained this purely isotrophic part, it is then possible, according to the invention, to calculate a second image representative of the non-isotrophic part of the scattering. This non-isotrophic part represents the anisotrophic transport of radiation induced by the medium at the moment of scattering.
    Type: Application
    Filed: June 13, 2007
    Publication date: March 18, 2010
    Applicant: Centre National De La Recherche Scientifique (CNRS)
    Inventor: Christophe BARAVIAN
  • NOVEL MARTERIALS INCLUDING ELEMENTS OF GROUP 14
    Publication number: 20100065775
    Abstract: The invention relates to a method for preparing a material including at least one member of the Group 14 by thermal degradation of a ternary phase, also known as the Zintl phase, or by reaction therewith an oxidising solvent. The invention also relates to the material containing at least one element of Group 14 that can be obtained by this method, and to the use thereof mainly in the field of electrochemistry, particularly for batteries. The material is more particularly suited for the field of batteries of the alkaline metal and/or alkaline-earth ions type, in particular of the lithium-ion type.
    Type: Application
    Filed: February 21, 2008
    Publication date: March 18, 2010
    Applicant: Centre National De La Recherche Scientifique - CNRS -
    Inventors: David Zitoun, Claude Belin, Monique Tillard
  • USE OF A COMBINATION OF IRON MONOXIDE AND SPINEL OXIDES AS A SENSITIVE MATERIAL FOR DETECTING INFRARED RADIATION
    Publication number: 20100065743
    Abstract: The invention relates to the use of a material having a spinel ferrite/iron monoxide structure as a sensitive material in the form of a thin film for the bolometric detection of infrared radiation, the chemical composition of said structure, excluding doping agents that may be present, having empirical formula (I): (Fe1?zMz)xO, where x is strictly less than 1 and strictly greater than 0.75. The invention also relates to a bolometric device for infrared radiation detection and infrared imaging, comprising at least one sensor provided with a sensitive element in the form of a thin film as defined above.
    Type: Application
    Filed: June 11, 2009
    Publication date: March 18, 2010
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE, UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Philippe TAILHADES, Lionel PRESMANES, Corinne BONNINGUE, Bruno MAUVERNAY, Jean-Louis OUVRIER-BUFFET, Agnes ARNAUD, Wilfried RABAUD
  • Sound-wave imaging method and apparatus
    Patent number: 7679988
    Abstract: An ultrasound imaging method including an emission step during which an array of transducers is caused to emit at an ultrasound wave focused in a target medium by causing the excitation wave to pass through a reverberant solid object prior to reaching the target medium.
    Type: Grant
    Filed: July 23, 2004
    Date of Patent: March 16, 2010
    Assignees: Centre National de la Recherche Scientifique -CNRS-, universite Paris 7 - Denis Diderot
    Inventors: Mathias Fink, Gabriel Montaldo, Mickael Tanter
  • CRYSTALLIZATION OF CHEMICAL SPECIES/POLYMORPHS AND MICROFLUIDIC APPARATUS AND SCREENING METHODOLOGY THEREFOR
    Publication number: 20100058845
    Abstract: The crystallization of chemical species/polymorphs comprises forming droplets of a solution of a substance with optionally different concentrations of said substance in an inert phase; producing and storing the droplets in at least one storage microchannel (1); forming crystals in all droplets; increasing the temperature in order to induce the dissolution of at least a portion of the crystals in at least some droplets; and analyzing the crystallization and dissolution process.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 11, 2010
    Applicants: RHODIA OPERATIONS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Mathieu Joanicot, Philippe Laval, Jacques Leng, Jean-Baptiste Salmon
  • GALLERY-MODE MICRODISC SYSTEM FOR ELECTRICALLY PUMPED OPTICAL SOURCES
    Publication number: 20100061416
    Abstract: The invention concerns a gallery mode microdisc system for an electrically pumped optical source, the microdisc (1) being formed on one face of a substrate (2), the lower part of the microdisc being provided with an electrical contact referred to as the lower contact (4), the upper part of the microdisc being provided with an electrical contact referred to as the upper contact (6), the upper part of the microdisc being covered with a protective layer (3) of electrically insulating material, the central part (5) of the microdisc being electrically neutralised in order to prevent the passage of an electric current in said central part.
    Type: Application
    Filed: March 9, 2009
    Publication date: March 11, 2010
    Applicants: Commissariat A L'Energie Atomique, Centre National De La Recherche Scientifique, Ecole Centrale De Lyon
    Inventors: Fabien Mandorlo, Jean-Marc Fedeli, Pedro Rojo-Romeo
  • CONTROLLED ATOMIC FORCE MICROSCOPE
    Publication number: 20100064397
    Abstract: The invention relates to an atomic force microscope including a microtip placed on a flexible support connected to a microscope head facing a surface to be studied, which includes means for controlling the distance between the head and the surface for a given value and means for inhibiting vibration of the microtip.
    Type: Application
    Filed: May 23, 2007
    Publication date: March 11, 2010
    Applicants: UNIVERSITE JOSEPH FOURIER, EUROPEAN SYNCHROTRON RADIATION FACILITY, INSTITUT NATIONAL POLYTECHNIQUE DE GRENOBLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Michal Hrouzek, Alina Anca Voda, Joel Chevrier, Gildas Besancon, Fabio Comin
  • INTEGRATED ELECTRONIC CIRCUIT INCLUDING A THIN FILM PORTION BASED ON HAFNIUM OXIDE
    Publication number: 20100059834
    Abstract: An integrated electronic circuit has a thin layer portion based on hafnium oxide. This portion additionally contains magnesium atoms, so that the portion is in the form of a hafnium-and-magnesium mixed oxide. Such a portion has a high dielectric constant and a very low leakage current. It is particularly suitable for forming a part of a gate insulation layer of a MOS transistor or a part of a MIM capacitor dielectric.
    Type: Application
    Filed: April 25, 2008
    Publication date: March 11, 2010
    Applicants: STMicroelectronics (Crolles) SAS, Centre National de La Recherche Scientifique - CNRS -, Institut National Polytechnique De Grenoble
    Inventors: Catherine Dubourdieu, Erwan Yann Ruawel, Vincent Cosnier, Sandrine Lhostis, Daniel-Camille Bensahel
  • Method for Detecting Aggregate-Forming Circulating Protein Forms Using an Agent for Aggregating Said Forms and an Agent for Capturing Formed Aggregates
    Publication number: 20100062540
    Abstract: The present invention concerns a method for detecting aggregate-forming circulating protein forms in a biological sample of human origin that may contain said aggregate-forming circulating protein forms, characterized in that it uses a non-protein agent I producing aggregation of the circulating forms of the noninfectious proteins involved in pathological aggregation processes of the central nervous system and/or a non-protein agent II for capturing the natural aggregrates of aggregate-forming circulating protein forms or the aggregates induced by said agents I.
    Type: Application
    Filed: July 7, 2006
    Publication date: March 11, 2010
    Applicants: BIOMERIEUX S.A., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1
    Inventors: Sébastien Cecillon, Anthony William Coleman, Anne Eveno-Nobile, Hervé Perron, Marc Rodrigue
  • BULK ACOUSTIC WAVE RESONATOR WITH ADJUSTABLE RESONANCE FREQUENCY AND USE OF SUCH A RESONATOR IN THE FIELD OF TELEPHONY
    Publication number: 20100060386
    Abstract: A bulk acoustic wave resonator has an adjustable resonance frequency. A piezoelectric element is provided having first and second electrodes. A switching element is provided in the form of a MEMS structure which is deformable between a first and second position. The switching element forms an additional electrode that is selectively disposed on top of, and in contact with, one of the first and second electrodes. This causes a total thickness of the electrode of the resonator to be changed resulting in a modification of the resonance frequency of the resonator.
    Type: Application
    Filed: January 15, 2008
    Publication date: March 11, 2010
    Applicants: STMicroelectronics (Crolles 2) SAS, Centre National de La Recherche Scientifique
    Inventors: Didier Belot, Andrea Cathelin, Yann Deval, Moustapha El Hassan, Eric Kerherve, Alexandre Shirakawa
  • POST-TRANSLATIONALLY MODIFIED NEUROTROPHINS
    Publication number: 20100055109
    Abstract: The present invention describes that neurotrophins undergo post-translational modifications, and that these post-translational modifications mediate the pro-apoptotic and/or pro-neurite activity of neurotrophins. These post-translational modifications notably include nitration and the formation of conformationally-different dimers, as well as of abnormal oligomers, such as tetramers and octamers. The invention further relates to compounds that compete with such modified neurotrophins, as well as to compounds that binds to said modified neurotrophins. The invention thus provides useful agents for the treatment of the conditions or diseases involving a chronic pain and/or neuron loss.
    Type: Application
    Filed: July 23, 2007
    Publication date: March 4, 2010
    Applicants: Institut Pasteur, Instituto De Investigaciones Biol. Clem. Estable, Facultad De Medicina, Universidad De La Republica, Centre National De La Recherche Scientifique
    Inventors: Luis Barbeito, Mariana Pehar, Patricia Cassina, Pedro M. Alzari
  • Cyclodipeptide Synthetase and its use for Synthesis of Cyclo(Tyr-Xaa) Cyclodipeptides
    Publication number: 20100055737
    Abstract: Isolated, natural or synthetic polynucleotide and polypeptide encoded by said polynucleotide, that is involved in the synthesis of cyclodipeptides, recombinant vector comprising said polynucleotide or any substantially homologous polynucleotide, host cell modified with said polynucleotide or said recombinant vector and also methods for in vitro and in vivo synthesizing cyclodipeptides, in particular cyclo(Tyr-Xaa) cyclodipeptides, wherein Xaa is any amino acid and their derivatives and applications thereof.
    Type: Application
    Filed: April 26, 2006
    Publication date: March 4, 2010
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Pascal Belin, Muriel Gondry, Robert Thai, Jean-Luc Pernodet, Roger Genet
  • METHOD AND DEVICE FOR THE REHABILITATION AND/OR CORRECTION OF POSTURAL SYMMETRY IN STATIC OR DYNAMIC SITUATIONS
    Publication number: 20100056957
    Abstract: A method for rehabilitation or correction of the postural symmetry of a person in static or dynamic situations includes the following steps: monitoring at least one parameter of at least one body part; detecting whether the parameter and/or a combination of parameters falls short of, or exceeds, a threshold value; and if so, warning the person by means of a lingual electrostimulation signal and informing the person of a postural response to be carried out in order to bring the value back to the threshold value.
    Type: Application
    Filed: June 11, 2007
    Publication date: March 4, 2010
    Applicants: UNIVERSITE JOSEPH FOURIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Nicolas Vuillerme, Yohan Payan, Jaques Demongeot
  • Controlled Distribution of Stereospecific Sites in Ziegler-Natta Catalyst Systems
    Publication number: 20100056736
    Abstract: This invention relates to an improved method for improving the tacticity of Ziegler-Natta catalyst systems and for controlling the behaviour of the active stereospecific sites.
    Type: Application
    Filed: April 4, 2007
    Publication date: March 4, 2010
    Applicants: TOTAL PETROCHEMICALS RESEARCH FELUY, Centre National de la Recherche Scientifique (CNR
    Inventors: David Ribour, Roger Spitz, Jerome Gromada
  • Calixarene Derivatives as Anticancer Agent
    Publication number: 20100056482
    Abstract: This invention relates to compounds having the following formula (I): of compositions including them, uses of these compounds, particularly for preparation of medicines, and in vitro induction processes for apoptosis and direct death of cancer cells.
    Type: Application
    Filed: April 18, 2007
    Publication date: March 4, 2010
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERITE CLAUDE BERNARD - LYON 1
    Inventors: William Anthony Coleman, Loris Gilbert Baggetto, Adina Nicoleta Lazar, Mickael Henri Michaud, Sandrine Magnard
  • GLUT-1 AS A RECEPTOR FOR HTLV ENVELOPES AND ITS USES
    Publication number: 20100056448
    Abstract: The invention relates to the use of the ubiquitous vertebrate glucose transporter GLUT1, or of fragments or sequences derived thereof, for the in vitro diagnosis of cancers, when used as a tumor marker, or for the screening of compounds useful for the preparation of drugs for the prevention or the treatment of pathologies linked to an infection of an individual with a PTLV, or pathologies linked to an overexpression of GLUT1 on cell surfaces, or the in vitro detection of GLUT1 on cell surfaces. The invention also relates to pharmaceutical compositions containing GLUT1, or fragments or sequences derived thereof, and to their uses such as in the frame of the prevention or the treatment of pathologies linked to an infection of an individual with a PTLV.
    Type: Application
    Filed: August 26, 2009
    Publication date: March 4, 2010
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE UNIVERSITE MONTPELLIER II
    Inventors: Jean-Luc Georges Laurent BATTINI, Nicolas Gabriel Albert Manel, Felix Jinhyun Kim, Sandrina Kinet, Naomi Taylor, Marc Sitbon
  • Piezoelectric motor allowing at least two degrees of freedom, in rotation and linear displacement
    Patent number: 7671513
    Abstract: A motor (1) includes a stator (4) and a rotor (6), the stator including piezoelectric actuators (11,12,21) for maneuvering staples (30A, 30Z) maintaining the stator and its linear displacement (L) along a guide (2), the actuators serving to drive the rotor in rotation (R).
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: March 2, 2010
    Assignees: Centre National de la Recherche Scientifique, Institut National Polytechnique de Toulouse
    Inventors: Marc René Christian Budinger, Jean-Francois Roland Rouchon, Bertrand Nogarede