Patents Assigned to CENTRE NATIONAL DE LA
  • Publication number: 20100010180
    Abstract: The present invention discloses an active supported catalyst system comprising: a) one or more non-metallocene catalyst component; b) an alkylating agent; c) an activating functionalised and fluorinated support. It also discloses a method for preparing said active support and its use in the polymerisation of polar and non polar monomers.
    Type: Application
    Filed: July 26, 2006
    Publication date: January 14, 2010
    Applicants: TOTAL PETROCHEMICALS RESEARCH FELUY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Floran Prades, Roger Spitz, Christophe Boisson, Sabine Sirol, Abbas Razavi
  • Publication number: 20100010781
    Abstract: The present invention relates to a method for modeling the interactions within a system between at least one object. The surface of each object defines an interface between at least two media. The set of elementary characteristic functions are chosen that correspond to the field of application in question. The physical properties of each medium considered composing the system are defined. Each object of the system is created by modeling it as a mesh and at least one elementary point source is associated with either side of each mesh element. The type of boundary conditions are determined for each interface. The global matrix for the interactions between the various objects is constructed, depending on the type of boundary conditions, the properties of the media and on the configuration of the system. The global matrix is inverted. The inverted matrix is multiplied by a column matrix containing the values of the excitation boundary conditions.
    Type: Application
    Filed: December 20, 2006
    Publication date: January 14, 2010
    Applicants: Centre National De La Recherche Scientifique, University of Arizona
    Inventors: Dominique Placko, Tribikram Kundu, Aurélie Cruau, Nicolas Liebeaux
  • Patent number: 7645740
    Abstract: Peptide of sequence TALRIRATYGEY (SEQ ID NO: 1) present on the gamma 2 chain of Laminin 5, a pharmaceutical composition containing the peptide and to the use of the composition for treating various skin alterations. More particularly, the treatment of the alterations includes reinforcing the derma-epidermal junction and the cell-matrix and/or cell-cell adherence of epidermis and in promoting the repair of a cutaneous surface.
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: January 12, 2010
    Assignee: Laboratoires d'Anjou Centre National de la Recherche Scientifique (CNRS)
    Inventor: Patricia Rousselle
  • Publication number: 20100004443
    Abstract: The present invention relates to linear pyridazine compounds, and more particularly to those of these compounds which are oligopyridazine compounds, to processes for obtaining them, to their uses, and also to their reduction to pyrroles and to the uses of the pyrrole, pyridazinylpyrrole and oligopyrrole compounds obtained. The invention relates in particular to the uses as medicaments, in particular for treating pathologies such as cancer, bacterial infections or parasitic infections, and also the applications in the materials, environmental, electronics and optics field.
    Type: Application
    Filed: July 26, 2007
    Publication date: January 7, 2010
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.
    Inventors: Didier Max Dubreuil, Muriel Geneviève Pipelier, Jean-Paul Pradere, Hicham Bakkali, Christine Geneviève Juliette Thobie, Eric Fredéric Leonel, Jean-Yves Joseph Maria Nedelec, Stephane Sengmany, Thierry Delaunay, Alexandra Tabatchnik
  • Patent number: 7642513
    Abstract: The inventive device for obtaining the electron energy loss image and/or spectra includes an image sensor, a control for at least two deflectors for alternately exposing at least two photosensitive parts of the image sensor, sensor reading means for generating the representative signal of an image captured by each photosensitive part of the image sensor, means for synchronizing the deflector and the reading means for successively controlling the exposition of the photosensitive part and the reading of the other photosensitive part for each photosensitive part and means for combining the two image parts in such a way that a spectrum is formed.
    Type: Grant
    Filed: August 1, 2005
    Date of Patent: January 5, 2010
    Assignees: Centre National de la Recherche Scientifique, Universite Paris SUD 11
    Inventors: Henri Pinna, Marcel Tence
  • Patent number: 7642521
    Abstract: The present invention concerns a system for the focusing and/or a collimation of an ion beam, in particular a beam of accelerated protons, wherein the system has a lens with a lens body that is permeable to the ion beam, wherein means for the generation of an in particular electrostatic field, propagating within the lens body and focusing the ion beam, are provided, wherein the lens body has a wall of low thickness, wherein the means for the field generation comprise a source of electromagnetic radiation, whose emitted beam is directed onto the outer side of the wall of the lens body, wherein the thickness of the wall and the quality of the electromagnetic radiation is chosen such that the radiation generates free electrons that emerge from the wall and accumulate on the exit side of the wall in an electron cloud.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: January 5, 2010
    Assignees: Heinrich-Heine Universitaet Duesseldorf, Université Pierre and Marie Curie (UPMC), The Queen's University of Belfast, The Centre National de la Recherche Scientifique, Ecole Polytechnique
    Inventors: Oswald Willi, Julien Fuchs, Marco Borghesi, Toma Toncian
  • Patent number: 7641715
    Abstract: The invention relates to a composite material, a method for controlling the thermal effects generated in a physicochemical process using said material, and applications of the material and the method. The composite material comprises an active solid and a phase change material. The phase change material takes the form of micronodules having an average size of between 1 micron and 5 millimeters and it is selected from materials with a liquid/solid phase change temperature of between ?150° C. and 900° C. The active solid is selected from solids that can be used in a method involving reversible physicochemical processes that are exothermic in one direction and endothermic in the opposite direction.
    Type: Grant
    Filed: November 24, 2003
    Date of Patent: January 5, 2010
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Xavier Py, Vincent Goetz
  • Patent number: 7642061
    Abstract: The invention relates to the use of the ubiquitous vertebrate glucose transporter GLUT1, or of fragments or sequences derived thereof, for the in vitro diagnosis of cancers, when used as a tumor marker, or for the screening of compounds useful for the preparation of drugs for the prevention or the treatment of pathologies linked to an infection of an individual with a PTLV, or pathologies linked to an overexpression of GLUT1 on cell surfaces, or the in vitro detection of GLUT1 on cell surfaces. The invention also relates to pharmaceutical compositions containing GLUT1, or fragments or sequences derived thereof, and to their uses such as in the frame of the prevention or the treatment of pathologies linked to an infection of an individual with a PTLV.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: January 5, 2010
    Assignees: Centre National de la Recherche Scientifique, Universite Montpellier II
    Inventors: Jean-Luc Georges Laurent Battini, Nicolas Gabriel Albert Manel, Felix Jinhyun Kim, Sandrina Kinet, Naomi Taylor, Marc Sitbon
  • Patent number: 7642051
    Abstract: The invention is directed to the induction of mitochondrial membrane permeabilization via the physical and functional interaction of the HIV-1 Vpr protein with the mitochondrial inner membrane protein ANT (adenine nucleotide translocator, also called adenine nucleotide translocase or ADP/ATP carrier). Reagents and methods for inducing and/or inhibiting the binding of Vpr to ANT, mitochondrial membrane permeabilization, and apoptosis are provided.
    Type: Grant
    Filed: July 8, 2005
    Date of Patent: January 5, 2010
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale, Centre National de la Recherche Scientifique, Universite de Technologie de Compiegne
    Inventors: Etienne Daniel Francois Jacotot, Guido Kroemer, Bernard Pierre Roques, Lena Edelman, Johan Hoebeke, Catherine Brenner-Jean, Anne-Sophie Belzacq
  • Publication number: 20090325289
    Abstract: The use of a cellular development inhibitor in a controlled manner in order to maintain an undifferentiated stem cell state, especially one of human stem cells, whereby cell division is permitted.
    Type: Application
    Filed: September 8, 2009
    Publication date: December 31, 2009
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: JACQUES ALEXANDRE HATZFELD, ANTOINETTE HATZFELD
  • Publication number: 20090326240
    Abstract: The present invention relates to a process for creating a Carbon-Carbon bond (C—C) or a Carbon-Heteroatom bond (C—HE) by reacting a compound carrying a leaving group with a nucleophilic compound carrying a carbon atom or a heteroatom (HE) that can substitute for the leaving group, creating a C—C or C—HE bond, wherein the reaction takes place in the presence of an effective quantity of a catalytic system comprising iron and copper.
    Type: Application
    Filed: July 4, 2007
    Publication date: December 31, 2009
    Applicants: Centre National de la Recherche Scientifique (C.N.R.S.), Ecole Nationale Superieure de Chimie de Montpellier
    Inventors: Marc Taillefer, Ning Xia, Armelle Ouali
  • Publication number: 20090326360
    Abstract: The invention relates to a method for automatic estimation of the growth potential of cerebral infarcts, particularly in the acute phase, that is to say in the six hours following survival of the stroke. The method includes sequences of diffusion MRI images are obtained, the apparent diffusion coefficient (ADC) is calculated at a multiplicity of points or voxels of the cortical parenchyma, and locating and delimiting the initial infarct and modelling the development of the infarct based on a growth model.
    Type: Application
    Filed: June 29, 2007
    Publication date: December 31, 2009
    Applicant: Centre National De La Recherche Scientifique (CNRS)
    Inventors: Sylvain Baillet, Yves Samson, Nidiyare Hevia-Montiel, Charlotte Rosso, Sandrine Deltour, Éric Bardinet, Didier Dormont
  • Publication number: 20090325438
    Abstract: The present invention relates to a method of grafting, by covalent bonding, hollow or solid composite capsules onto any type of natural, artificial or synthetic, organic or inorganic, support, the capsules being chemically, physically or physico-chemically modified, so as possibly to improve their affinity with the support and to functionalize them, and then grafted, after the capsules and/or the support have been activated. The invention also relates to the capsules thus modified, to the supports grafted by the capsules, especially fibres and textiles, and also to the use of these grafted supports, especially fibres and textiles, for making up what are called “functional” articles.
    Type: Application
    Filed: February 19, 2007
    Publication date: December 31, 2009
    Applicant: Centre National De La Recherche Scientifique (C.N.R.S.)
    Inventors: Yves Frere, Louis Danicher, Mahdi Merji
  • Publication number: 20090321398
    Abstract: The invention relates to a method and device for machining a target using a femtosecond laser beam. The invention consists in taking advantage of the deterministic nature of the ablation threshold and the nonlinear dependence thereof through the use of amplitude or phase pupillary filtering using the polarising effect or any other technique in order to reduce significantly the machining dimensions obtained by focusing a laser beam in nanotechnologies. One such filtering process modifies the distribution of the intensity in the focal plane such as to reduce the maximum of the central component of the spectrum of laser pulses while maintaining the bright rings below the deterministic ablation threshold. The invention associates the femtosecond ablation technique with deterministic threshold and the apodisation technique.
    Type: Application
    Filed: June 28, 2007
    Publication date: December 31, 2009
    Applicants: ECOLE POLYTECHNIQUE, ECOLE NATIONALE SUPERIEURE DES TECHNIQUES AVANCEES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Gerard Mourou, Gilbert Boyer
  • Patent number: 7638831
    Abstract: A molecular memory including a substrate made of silicon; a set of condensers, each condenser including two conductive layers constituting armatures of the condensers and between which is placed a dielectric layer; and a connector to provide electric contacts with external circuits, wherein the dielectric layer comprises at least partially a polymer containing triazole derivatives, a spin transition phenomenon support material or a spin transition molecular complex; and a method for manufacturing a molecular memory including covering a substrate with a conductive layer; coating a dielectric material on the conductive layer; covering the dielectric material with the conductive layer; impregnating by immersion a buffer in an inking solution of hexadecanethiol; drying and washing the impregnated buffer; creating a protective monolayer on the conductive layer by application of the impregnated, dried and washed buffer; and creating a chemical etching on the sample.
    Type: Grant
    Filed: August 29, 2002
    Date of Patent: December 29, 2009
    Assignee: Centre National de la Recherche Scientifique - CNRS
    Inventors: Azzedine Bousseksou, Christophe Vieu, Jean-Francois Letard, Philippe Demont, Jean-Pierre Tuchagues, Laurent Malaquin, Jerôme Menegotto, Lionel Salmon
  • Publication number: 20090318382
    Abstract: A method comprises preventing or inhibiting bacterial adhesion and/or bacterial biofilm development by treating a substrate with a composition of a soluble group II capsular polysaccharide obtained from a bacterial strain.
    Type: Application
    Filed: June 25, 2007
    Publication date: December 24, 2009
    Applicants: INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Marc Ghigo, Jaione Valle, Sandra Da Re
  • Publication number: 20090319122
    Abstract: The invention relates to a method for the transmission of data relating to the actuation of a member used to operate a vehicle, in which code words are transmitted along the length of a given channel, each of said code words resulting from the channel coding of a block of information symbols that is representative of the aforementioned data. According to the invention, at least two such successive blocks of information symbols are coded using two different codes. The invention also relates to a data transmission system that is used to implement said method.
    Type: Application
    Filed: October 21, 2005
    Publication date: December 24, 2009
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, AIRBUS FRANCE
    Inventors: Jean-Jacques Aubert, Patrice Brot, Agnan De Bonneval, Yves Crouzet, Anis Youssef
  • Publication number: 20090315001
    Abstract: Process for preparing a ceramic from an inorganic base material that is in the form of a powder having a high melting point, comprising a step of mixing the powder of the inorganic base material with a second inorganic component also in powder form and which acts as a dopant for the inorganic base material. The dopant is constituted by a single inorganic material or by a mixture of at least two inorganic materials having a dopant effect on the inorganic base material. The process comprises a sintering step carried out at a high temperature. The ceramics obtained, because of their high density, are advantageously used as a target element. Films and electrodes obtained from these ceramics exhibit particularly advantageous properties.
    Type: Application
    Filed: May 17, 2007
    Publication date: December 24, 2009
    Applicants: HYDRO-QUEBEC, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Guy Campet, Iyad Saadeddin, Karim Zaghib
  • Patent number: 7635689
    Abstract: 2? and/or 3? prodrugs of 1?, 2?, 3? or 4?-branched nucleosides, and their pharmaceutically acceptable salts and derivatives are described. These prodrugs are useful in the prevention and treatment of Flaviviridae infections, including HCV infection, and other related conditions. Compounds and compositions of the prodrugs of the present invention are described. Methods and uses are also provided that include the administration of an effective amount of the prodrugs of the present invention, or their pharmaceutically acceptable salts or derivatives. These drugs may optionally be administered in combination or alteration with further anti-viral agents to prevent or treat Flaviviridae infections and other related conditions.
    Type: Grant
    Filed: December 6, 2004
    Date of Patent: December 22, 2009
    Assignees: Idenix Pharmaceuticals, Inc., Universita Degli Studi di Cagliari, Centre National de la Recherche Scientifique, L'Universite Montpellier II
    Inventors: Paola LaColla, Richard Storer, Gilles Gosselin, Jean-Pierre Sommadossi
  • Patent number: 7636070
    Abstract: An antenna, permitting the configuration of at least one radioelectric wave beam of at least one fixed wavelength, of the type including at least one transmitting element, preferably of the passive type, arranged in a set of essentially parallel, wave-reflecting wires or bars, made from a photonic band gap (BIP) material and forming a given structure. The given structure includes faults for shaping the at least one beam in a direction as a function of the position and/or the configuration of the faults. The wires or bars and the faults are arranged on a set of N curves which are closed and concentric on a plane, N being greater than or equal to 1 and the transmitting element is arranged within the innermost curve. The curves are preferably circular and the wires/bars can be controlled to pass from a wave-conducting/reflecting state to a transparent state.
    Type: Grant
    Filed: November 26, 2004
    Date of Patent: December 22, 2009
    Assignees: Centre National de la Recherche Scientifique, Universite de Rennes 1, Universite Paris Sud (Paris XI)
    Inventors: André De Lustrac, Kouroch Mahdjoubi, Anne-Claude Tarot, Halim Boutayeb, Claude Terret