Abstract: A cosmetic composition including diacetylresveratryl thioctate and a solvent. The solvent has a h value less than or equal to 8 and a d value greater than or equal to 16.9. Also, the use of the abovementioned composition to prevent and/or combat skin ageing.

Abstract: At least one microRNA selected from among hsa-miR-330, hsa-miR-7 and hsa-miR-137, the mature forms thereof, and the precursors thereof, for depigmenting the skin, and an in vitro method for identifying depigmenting compounds, which includes the steps of: a) placing at least one test compound in contact with a sample of melanocytes; b) measuring the expression or activity of at least one microRNA selected from among miR-330, miR-7 and miR-137, the mature forms thereof, and the precursors thereof, in the melanocytes; c) selecting the compounds for which at least 20% activation of the expression or of the activity of at least one of the microRNAs is measured in the melanocytes treated in a) by an element for comparing with the untreated melanocytes.

Abstract: A case for a cosmetic or body hygiene product comprises a body having a bottom and a free edge 2B and containing a dish 5 containing a solid, pasty or pulverulent product, and a lid 3 mounted pivotably on the body.

Abstract: A dispensing bottle-top 10 for bottles for products of liquid or viscous consistency includes a bottle-top body (20) adapted to be mounted on a bottle and including a feed cavity (13) and a top piece (30) adapted to be moved relative to this body between an inactive configuration in which a product dispensing orifice (35) is blocked and an active configuration in which this dispensing orifice (35) is exposed to the outside and communicates with the feed cavity (13). This bottle-top has a lateral wall that is advantageously cylindrical and is formed by the body 20 and, in said inactive configuration, an upper wall consisting entirely of the upper wall of the top part 30. This cylindrical body and this top part have complementary part-spherical surfaces adapted to slide one along the other with a relative movement and being connected by complementary retaining and guiding elements that remain hidden by this top part in each of the active and inactive configurations thereof.

Abstract: An in vitro method for screening for candidate compounds for preventing and/or attenuating skin ageing, and/or hydrating skin, includes: a) contacting a test compound with a sample of papillary fibroblasts; b) measuring the expression of a gene selected from PDPN, CCRL1 and NTN1, in the papillary fibroblasts; and c) selecting compounds for which an activation of at least 1.5 fold of the expression of at least one of the genes is measured in the treated papillary fibroblasts compared with untreated papillary fibroblasts. Another in vitro method includes: a) contacting a test compound with a sample of reticular fibroblasts; b) measuring the expression of a gene selected from MGP, PPP1R14A and TGM2, in the reticular fibroblasts; and c) selecting compounds for which an activation of at most 1.0 fold of the expression of at least one of the genes is measured in the treated reticular fibroblasts compared with untreated reticular fibroblasts.

Abstract: Esters of O-substituted hydroxy carboxylic acids are provided having Formula 1, or 2, or both Formulas 1 and 2: wherein R and R1 are independently selected from the group consisting of substituted and unsubstituted, branched- and straight-chain, saturated, unsaturated, and polyunsaturated C1-C22 alkyl, substituted and unsubstituted C3-C8 cycloalkyl, substituted and unsubstituted C6-C20 carbocyclic aryl, and substituted and unsubstituted C4-C20 heterocyclic; wherein the heteroatoms are selected from sulfur, nitrogen, and oxygen; and wherein n is 1-6. Process of producing esters of O-substituted hydroxy carboxylic acids are also provided.

Abstract: The dispenser member for dispensing fluid, the dispenser member includes: a nozzle; a shutter of the nozzle; and at least one magnet that is suitable for moving the shutter relative to the nozzle.

Abstract: A composition for external use containing a physiologically acceptable salt of a tranexamate as an active ingredient, which is dispersed in the composition in the state of fine particles, is provided. Thereby, a physiologically acceptable salt of the tranexamate is dissolved in a solvent to prepare a solution, to which a salting-out agent is added to precipitate the salt. Such salt is so dispersed in a composition for external use in the state of fine particles that the tranexamate salt can be mixed without using a large amount of an oil component to obtain a composition for external use affording excellent feel of use and stability.

Abstract: The present invention relates to a cosmetic composition containing an extract of flowers of Camellia Japonica Alba Plena, as well as the cosmetic use thereof, for moisturizing and/or protecting human skin against drying. It also relates to an extract of flowers of Camellia Japonica Alba Plena, characterized in that it can be obtained by extraction of flowers by at least one alcoholic solvent.

Abstract: Disclosed is a stable cosmetic composition having a syrupy texture while not being sticky, and translucent (or even transparent) appearance. Further disclosed is a method of preparation of such composition, as well as a method of its use.

Abstract: The invention relates to an extract of Vanilla planifolia, consisting in a liposoluble fraction, to a cosmetic or dermatological composition containing it, and to cosmetic and dermatological methods using same, especially in the treatment of skin ageing.

Abstract: A cosmetic or dermatological composition contains, in a physiologically acceptable medium, at least one compound from Formula (I). A method of using the composition, for reducing or preventing pigmenting, and/or whitening and/or lightening of the skin is described, as well as novel compounds from Formula (I?) that are included in Formula (I).

Abstract: The applicator for applying a composition to the eyelashes includes a stem and a brush including at least two independent supports following one after the other along an axis of the stem, each support carrying projections that present respective bases. At least one group of at least four consecutive bases of each support form a regular succession about the axis, two of the bases of the group constituting two ends that terminate the succession.

Abstract: A composition for external use containing a physiologically acceptable salt of a tranexamate as an active ingredient, which is dispersed in the composition in the state of fine particles, is provided. Thereby, a physiologically acceptable salt of the tranexamate is dissolved in a solvent to prepare a solution, to which a salting-out agent is added to precipitate the salt. Such salt is so dispersed in a composition for external use in the state of fine particles that the tranexamate salt can be mixed without using a large amount of an oil component to obtain a composition for external use affording excellent feel of use and stability.

Abstract: The invention relates to the identification and the use of compounds which activate the expression of at least one gene selected from LARGE, HS6ST2 and ST8SIA1, for preventing and/or attenuating ageing, and/or for hydrating skin. The invention thus relates to an in vitro method for screening for candidate compounds for preventing and/or attenuating ageing of the skin, and/or for hydrating the skin, including the following steps: a. bringing at least one test compound in contact with a sample of keratinocytes; b. measuring the expression of at least one gene selected from LARGE, HS6ST2 and ST8SIA1, in the keratinocytes; c. selecting the compounds for which an activation of at least 1.4 fold of the expression of at least one of the genes is measured in the keratinocytes treated in a. compared with the untreated keratinocytes.

Abstract: Identification and use of compounds which inhibit the expression or activity of micro-RNAs for preventing and/or attenuating ageing. An in vitro method for screening for candidate compounds for preventing and/or attenuating ageing of the skin including (a) bringing at least one test compound in contact with a sample of fibroblasts, (b) measuring the expression or the activity of at least one microRNA chosen from miR-134 and miR-152 in said fibroblasts, and (c) selecting the compounds for which an inhibition of at least 20%, preferably at least 30%, preferably at least 40% of the expression or an inhibition of at least 20%, preferably at least 30%, preferably at least 40% of the activity of at least one microRNA is measured in the fibroblasts treated in (a) compared with the untreated fibroblasts.

Abstract: A method for producing a composition for external use containing a physiologically acceptable salt of a tranexamate as an active ingredient, which is dispersed in the composition in the state of fine particles, includes dissolving a physiologically acceptable salt of the tranexamate in a solvent to prepare a solution, to which a salting-out agent is added to precipitate the salt. Such salt is so dispersed in a composition for external use in the state of fine particles, that the tranexamate salt can be mixed without using a large amount of an oil component to obtain a composition for external use affording excellent feel of use and stability.

Abstract: Cosmetic water-in-oil emulsion compositions containing solid particles and high concentrations of a specific silicone elastomer and including high content of polysilicon-11, solid particles providing at least one optical effect, and at least one silicon emulsifier are suitable for use for making up the face and/or lips or eyelids, preferably as foundations. They may also be used to as a base for make-up, or as a skin care cream to be applied on the body or face. These compositions result in a product that enhances the overall appearance of the skin by providing strong blurring effects to give anti-wrinkle/fine line effects, skin smoothness, and radiance while unifying color complexion. These compositions also have unique sensorial properties.

Abstract: The cosmetic product device comprises a container presenting an orifice for dispensing a product; and a cap presenting an internal portion in relief, such as a lip, arranged to pass over the orifice while closing the container with the cap, and to lie at a distance from the orifice when the cap closes the container. The cap is arranged in such a manner that while it is keeping the container closed it bears against the orifice and closes it.

Abstract: Disclosed is an oil-in-water type emulsion composition containing a physiologically acceptable salt of a tranexamate ester and a method for producing the same. An oil-in-water type emulsion composition containing a physiologically acceptable salt of a tranexamate ester can be obtained by preparing an oil phase including: A) a physiologically acceptable salt of a tranexamate ester; B) an amphiphilic substance; C) an oily substance; and D) water, a water-soluble organic solvent or a mixture thereof wherein the weight ratio of the ingredients A:B is in the range of 1:0.5 to 1:2.5, the weight ratio of the ingredients A:C is in the range of 1:1 to 1:5.0, and the weight ratio of the ingredients A:D is 1:0.2 to 1:5.0, and adding the oil phase to a water phase including E) water, a water-soluble organic solvent or a mixture thereof.