Patents Assigned to Cheng
  • Patent number: 8917779
    Abstract: The invention provides an electrocardiogram signal compression and de-compression system. The invention uses the sign characteristics of the coefficients of the discrete cosine transform type IV and the characteristics of quantization of spectrum to perform the differential pulse code modulation of the spectrum for preserving the high frequency characteristics of the spectrum of the discrete Fourier transform. The invention also uses the Huffman coding to increase the compression ratio. Different from the conventional compression technology, the invention uses the fact that the quantization values of the spectrum in the high frequency are almost the same to increase the compression ratio and preserve the characteristics of high frequency components of the spectrum.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: December 23, 2014
    Assignee: National Cheng Kung University
    Inventors: Sheau-Fang Lei, Shin-Chi Lai, Chien-Sheng Lan
  • Patent number: 8917938
    Abstract: A method for estimating blur degree of image and a method for evaluating image quality are revealed. First, an input image is transmitted to an image processing device for producing a synthesized blur image including a nonlinear image sensing function according to a pixel intensity distribution parameter of the input image. Next, the image processing device matches the pixel intensity distribution according to the input image and the synthesized blur image for producing a blur degree parameter; By the way, the image processing device further estimating an estimated blur result according to the blur degree parameter. The method for estimating blur degree of image can be further applied to estimate blur distribution for a plurality of regions of interest of a plurality of input images. Thereby, the blur distribution of the input images can be estimated, and thus further evaluating the image quality of the plurality of input images.
    Type: Grant
    Filed: November 23, 2012
    Date of Patent: December 23, 2014
    Assignee: National Chung Cheng University
    Inventors: Huei-Yung Lin, Xin-Han Zhou
  • Publication number: 20140370015
    Abstract: Alleviating neural injury, such as spinal cord injury, in a subject (e.g., a human subject) in need of the treatment using an IL-20 antagonist, which can be an antibody that blocks a signaling pathway mediated by IL-20. Such antibodies include anti-IL-20 antibodies and anti-IL-20R antibodies that specifically block the IL-20 signaling pathway.
    Type: Application
    Filed: June 17, 2014
    Publication date: December 18, 2014
    Applicant: National Cheng Kung University
    Inventors: Ming-Shi Chang, I-Ming Jou
  • Publication number: 20140370014
    Abstract: Alleviating obesity in a subject (e.g., a human subject) having, being suspected of having, or at risk for obesity using an IL-20 antagonist, which can be an antibody that blocks a signaling pathway mediated by IL-20. Such antibodies include anti-IL-20 antibodies and anti-IL-20R antibodies that specifically block the IL-20 signaling pathway.
    Type: Application
    Filed: June 17, 2014
    Publication date: December 18, 2014
    Applicant: National Cheng Kung University
    Inventors: Ming-Shi Chang, Yu-Hsiang Hsu
  • Patent number: 8911989
    Abstract: The present invention provides a microfluidic biochip, which comprises: a fluid transportation unit having a fluid transportation reservoir and a fluid transportation air chamber; a first fluid storage reservoir; a second fluid storage reservoir; a first valve unit having a first valve and a first valve control air chamber; and a second valve unit having a second valve and a second valve control air chamber; wherein the first valve unit is located between the first fluid storage reservoir and the fluid transportation unit, the second valve unit is located between the second fluid storage reservoir and the fluid transportation unit, and the top portion of the fluid transportation reservoir and the valves are made of a flexible material. The structure of the present microfluidic biochip allows fluids to be transported and/or mixed therein.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: December 16, 2014
    Assignee: National Cheng Kung University
    Inventors: Gwo-Bin Lee, Sung-Yi Yang, Song-Bin Huang, Kang-Yi Lien, Chen-Hsun Weng
  • Patent number: 8912155
    Abstract: A method for analyzing secretome, a biomarker for lung cancer metastasis, and a siRNA compound for inhibiting lung cancer metastasis are disclosed. The method for analyzing secretome of the present invention comprises the following steps: (A) collecting proteome secreted from a cell; (B) providing a purification gel, wherein the purification gel comprises a low-density layer, and a high-density layer, and the low-density layer is stacked on the high-density layer; (C) adding the proteome on the low-density layer, and separating the proteome through the low-density layer and the high-density layer of the purification gel; (D) collecting the separated proteome on the interface between the low-density layer and high-density layer, and tagging the separated proteome with a reagent after digestion; and (E) analyzing the separated proteome tagged with the reagent, and comparing an analysis result with a proteomic database.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: December 16, 2014
    Assignee: National Cheng Kung University
    Inventors: Pao-Chi Liao, Ying-Hwa Chang, Kuo-Hsun Chiu, Yu-Shun Wu, Shu-Hui Lee
  • Patent number: 8911605
    Abstract: A method of antibiotic susceptibility testing is disclosed, and includes the following steps: (A) providing a sample to be tested wherein the sample contains a microbe; (B) adding an antibiotic into the sample, wherein the antibiotic serves to inhibit cell wall synthesis; (C) checking the sample by dielectrophoresis and observing a shape change of the microbe; and (D) determining whether the microbe is susceptible to the antibiotic according to the shape change thereof. The present invention also discloses a method for determining a minimum inhibitory concentration of the antibiotic.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: December 16, 2014
    Assignee: National Cheng Kung University
    Inventors: Cheng-Che Chung, I-Fang Cheng, Wen-Horng Yang, Hsien-Chang Chang
  • Patent number: 8911323
    Abstract: A multi-ratio transmission system is provided, including multiple planet gear sub-systems, at least two coupling assemblies, a setting element, a setting element controller, an annular gear, a cylindrical casing, a sprocket, and a central axle. The planet gear sub-systems are disposed coaxially in series along a first axis. Each of the planet gear sub-system includes a sun gear and at least one planet gear. Each coupling assembly transmits the rotation between every two adjacent planet gear sub-systems. The setting element optionally engages with the sun gear. The annular gear is installed onto a one-way clutch. The cylindrical casing encloses the planet gear sub-systems. The sprocket is installed onto the planet gear sub-systems through the one-way clutch. The central axle enables the hollowed tube of the setting element controller to rotate around the central axle.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: December 16, 2014
    Assignee: Cheng Ho Chen
    Inventor: Cheng Ho Chen
  • Publication number: 20140361832
    Abstract: An operational transconductance amplifier for connection with multiple input voltage sources includes a resistance simulation unit, two current cancellation units, a first differential output unit, two current division units, and a second differential output unit. The resistance simulation unit is to simulate resistance. The two current cancellation units are to receive and convert the voltage of the input voltage sources into two first currents. The two first currents flow to two first output ends of the first differential output unit, respectively. The two current division units are to receive and convert the voltage of the input voltage sources into two second currents. The two second currents flow to two second output ends of the two second differential output units, respectively, and include the same potential as the two first currents.
    Type: Application
    Filed: August 13, 2013
    Publication date: December 11, 2014
    Applicant: National Chung Cheng University
    Inventors: Shuenn-Yuh LEE, Cheng-Pin WANG, Jia-Feng TSAI
  • Publication number: 20140364374
    Abstract: The invention relates to an amino acid sequence for inhibiting PTX3 to treat nasopharyngeal carcinoma. It can be used to inhibit PTX3 from promoting the migration and invasion of nasopharyngeal carcinoma cells, promoting angiogenesis and inhibiting macrophage phagocytosis to further treat nasopharyngeal carcinoma.
    Type: Application
    Filed: October 2, 2013
    Publication date: December 11, 2014
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: JU-MING WANG, YU-WEI HSIAO
  • Publication number: 20140362192
    Abstract: A measurement method for environment depth and the image extraction device thereof is revealed. First, rotate an image extraction unit and extract a plurality of images using an image extraction device according to different viewing angles of a target object. Then, use disparity information of the plurality of images and an image parameter of the image extraction unit to give a plurality pieces of depth-of-field information, which are further used for giving environment depth information. The image extraction device has an image extraction unit and a rotating member. The rotating member is connected with the base; the rotating member is connected to the image extraction unit, which is located on one side of the rotating member. The plurality of images with different viewing angles are extracted to the image extraction unit as the rotating member rotates about a rotating center to different image extracting locations.
    Type: Application
    Filed: July 26, 2013
    Publication date: December 11, 2014
    Applicant: NATIONAL CHUNG CHENG UNIVERSITY
    Inventors: HUEI-YUNG LIN, CHUN-LUNG TSAI
  • Patent number: 8906605
    Abstract: An analytical method of post-translational modifications in hemoglobin is disclosed. The analytical method comprises the steps of providing a blood comprising the hemoglobin with post-translational modification of nitration, nitrosylation, or oxidation; performing an extraction process to the blood by an organic solvent; quantifying the hemoglobin by a fluorescent spectrometry; hydrolyzing the hemoglobin into a plurality of peptides by an enzyme; and using a nanoflow liquid chromatography-nanospray ionization tandem mass spectrometry to characterize and quantify the post-translational modifications of the hemoglobin.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: December 9, 2014
    Assignee: National Chung Cheng University
    Inventors: Hauh-Jyun Candy Chen, Yu-Chin Chen
  • Publication number: 20140353010
    Abstract: An electronic component includes a flexible printed circuit board which has a main body, a fixing portion and a connecting portion, and an insulating portion integrally molded to the fixing portion. In the process of the insulating portion being molded to the fixing portion, a filling mold fixture is sleeved around and spaced from outsides of the fixing portion. A method of manufacturing the electronic component is described hereinafter. Sleeve the filling mold fixture around the fixing portion and apart from the outsides of the fixing portion. Place the flexible printed circuit board together with the filling mold fixture in a mold. Inject liquid rubber into the filling mold fixture. Close the mold. Cool the electronic component and the filling mold fixture. Open the mold to take out the electronic component and the filling mold fixture, and then separate the filling mold fixture from the electronic component smoothly.
    Type: Application
    Filed: May 29, 2013
    Publication date: December 4, 2014
    Applicant: Cheng Uei Precision Industry Co., Ltd.
    Inventor: Chih Wei Wang
  • Publication number: 20140353447
    Abstract: A supporting device includes a holding module and a locating module. The holding module includes a rear shell and a front shell which have a bottom positioning shell and a top positioning shell covered to define a receiving chamber therebetween. The locating module is movably disposed in the receiving chamber and includes a supporting part, a slide part mounted on the supporting part and slidable forward and backward, a locating part fixed on the slide part and projecting out of the top positioning shell, and an elastic part clamped between the supporting part and the bottom positioning shell. The locating part is located in front of the front shell with a distance therebetween being adjustable by the locating part along with the slide part sliding forward and backward. The supporting part together with the slide part and the locating part can move upward and downward by the elastic part.
    Type: Application
    Filed: May 29, 2013
    Publication date: December 4, 2014
    Applicant: Cheng Uei Precision Industry Co., Ltd.
    Inventor: Yung Cheng Chuang
  • Publication number: 20140354992
    Abstract: A localized surface plasmon resonance (LSPR) sensing system with particles arranged in anisotropic periodic manner is revealed. The anisotropy of the nanoparticle array spectrally splits the phase spectra of two perpendicular polarizations thus inducing a phase difference between the two polarizations. An apparatus of ellipsometry is used to measure the phase difference. The simulated results demonstrate that the full width at the half maximum of the spectrum of phase difference is much narrower than the spectrum of transmittance.
    Type: Application
    Filed: November 15, 2013
    Publication date: December 4, 2014
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: CHUN-HUNG LIN, WEN-YU CHEN
  • Publication number: 20140354993
    Abstract: A localized surface plasmon resonance (LSPR) sensing system with anisotropic particles is revealed. The anisotropy of nanoparticles spectrally splits the phase spectra of two perpendicular polarizations thus inducing a phase difference between the two polarizations. An apparatus of ellipsometry is used to measure the phase difference. The simulated results demonstrate that the full width at the half maximum of the spectrum of phase difference is much narrower than the spectrum of transmittance. Therefore the figure of merit is dramatically increased and the performance of the refractive index sensor is improved.
    Type: Application
    Filed: November 15, 2013
    Publication date: December 4, 2014
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: CHUN-HUNG LIN, WEN-YU CHEN
  • Patent number: 8902420
    Abstract: The present invention relates to a sensor chip for biomedical and micro-nano structured substances and a method for manufacturing the same. The sensor chip includes plural metal nanoparticles and a porous anodized aluminum oxide film. The plural metal nanoparticles are completely contained in holes of the porous anodized aluminum oxide film and located at the bottom of the holes, and an aluminum oxide layer covering the second end of the holes has a thickness of 1 nm to 300 nm. When analytes such as biomedical molecules are provided in contact with the sensor chip, a Raman signal can be detected based on the Raman spectroscopy. The structure of the sensor chip of the present invention is uncomplicated and the manufacturing steps thereof are simple, and therefore the sensor chip of the present invention is of great commercial value. Also, a method of manufacturing the above sensor chip is disclosed.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: December 2, 2014
    Assignee: National Cheng Kung University
    Inventors: Yon-Hua Tzeng, Chih-Yi Liu, Chen-Han Huang, Hsing-Ying Lin, Hsiang-Chen Chui, Kyaw-Oo Lau, Shih-Tse Chen, Cheng-Wen Huang
  • Patent number: 8902385
    Abstract: A polymer film without cholesteric liquid crystal (LC) is characterized in that the polymer film has photonic crystal structure. The polymer film is an innovative product in the feature of having photonic crystal structure without containing cholesteric LC. In addition, the polymer film can further contain fluid which is filled in the film body of the polymer film. By filling any of various fluids in the film body, the light of different wavelengths can be reflected by the polymer film based on Bragg reflection, so that the applications of the polymer film can be broadened. Especially when the fluid is anisotropic liquid, the polymer film can be applied to electro-controlled reflective display modules. In addition, stacking the imprinted polymer films manufactured from left-handed and right-handed cholesteric liquid crystals can improve the brightness of reflected light.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: December 2, 2014
    Assignee: National Cheng Kung University
    Inventor: Jui-Hsiang Liu
  • Publication number: 20140350647
    Abstract: An electromagnetic hyperthermia assembly includes: a substrate; a plurality of hyperthermia needles each having a needle portion that extends through and downwardly from the substrate and that has a needle tip distal from the substrate; and a guiding plate having a plurality of through holes. The needle portions of the hyperthermia needles respectively and removably extend through the through holes such that the guiding plate is movable along the needle portions and between the substrate and the needle tips of the needle portions. The through holes keep the needle tips spaced apart from each other at predetermined positions.
    Type: Application
    Filed: May 19, 2014
    Publication date: November 27, 2014
    Applicants: NATIONAL CHENG KUNG UNIVERSITY, METAL INDUSTRIES RESEARCH & DEVELOPMENT CENTRE
    Inventors: Yi-San CHANG, Tsung-Chih YU, Xi-Zhang LIN, Sheng-Jye HWANG, Ying-Jui CHAO, Syuan-Fong CHEN, Guan-Cheng CHEN, Tung-Chieh YANG, Shyang-Jye CHANG
  • Publication number: 20140351319
    Abstract: A portable electronic apparatus includes an operating system comprising an application layer, an application framework layer, a libraries layer and a kernel layer. The application layer includes a cloud user interface allowing a user to perform an interactive function. The application framework layer includes a plurality of cloud components and at least a cloud service. The libraries layer includes a plurality of cloud managers. The kernel layer includes a cloud server driver, which is connected to the cloud managers to start the cloud service, so that the cloud service calls one of the cloud components according to the interactive function. By such configuration, the portable electronic apparatus of this invention can carry a private cloud to provide the service of a portable personal cloud.
    Type: Application
    Filed: August 1, 2013
    Publication date: November 27, 2014
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Chiang LEE, Chao-Hsien HSIEH