Abstract: A novel compound having NMDA receptor channel blocking activity, is provided. A pharmaceutical agent comprising the compound is also provided. The pharmaceutical agent can be used for the treatment or prevention of a disease caused by overexcitation of an NMDA receptor, and can comprise a compound having NMDA receptor channel blocking activity and represented by the formula (1), or a pharmaceutically acceptable salt thereof.

Abstract: A medicinal preparation for preventing and/or treating psychoneurotic diseases such as integration dysfunction and Alzheimer's disease which contains tropisetron or its pharmaceutically acceptable salt as the active ingredient.

Abstract: [Object] The object is to provide a functional composite material which is adaptable to environmental changes. [Means for Achieving the Object] The present invention provides a method for producing a functional composite material comprising a step wherein an insert layer is formed on a first metal substrate having a groove; a step wherein a piezoelectric fiber having a metal core is placed on the first metal substrate; and a step wherein a second metal substrate and the first metal substrate are hot-pressed. The present invention can provide a functional composite material which is adaptable to environmental changes.

Abstract: There is provided a composition for electrochromic devices which clearly present only two states, a white-colored state and a decolored state. The composition for electrochromic devices contains (A) a specific quaternary ammonium salt, (B) a supporting electrolyte containing bromide ion, and (C) a solvent containing water as an essential component, and (A) is soluble in (C).

Abstract: A method of treating or reducing at least one inflammatory condition or the susceptibility to at least one inflammatory condition is provided involving administering at least one CD69 antagonist to a subject, wherein the subject has been diagnosed with at least one inflammatory condition, or a susceptibility to the same. CD69 antagonists can include one or more of an anti-CD69 antibody, an anti-CD69 aptamer, a CD69 mRNA antagonist, and a small molecule pharmaceutical.

Abstract: To solve the problems in the prior art, the present invention provides a method for measuring a time difference between digital video signals and digital audio signals, wherein said method comprises the steps of extracting respective time series data from respective frequency domains of said digital video signals and said digital audio signals; statistically identifying the cross-correlation of said time series data in said frequency domains, thereby measuring the time difference between said digital video signals and said digital audio signals.

Abstract: The present invention is directed to a unique mammalian cell line expressing inducible c-Src, and, particularly, a unique human cell line overexpressing c-Src in an inducible manner.

Abstract: Provided is a high-strength and high-toughness magnesium alloy which has practical level of both the strength and the toughness for expanded applications of the magnesium alloys, and is a method for manufacturing thereof. The high-strength and high-toughness magnesium alloy of the present invention contains: a atom % in total of at least one metal of Cu, Ni, and Co; and b atom % in total of at least one element selected from the group consisting of Y, Dy, Er, Ho, Gd, Tb, and Tm, while a and b satisfying the following formulae (1) to (3), 0.2?a?10??(1) 0.2?b?10??(2) 2/3a?2/3<b.

Abstract: A method of producing a zinc oxide-based semiconductor crystal, including: introducing at least zinc and oxygen on a surface of a substrate; and growing a zinc oxide-based semiconductor crystal on the substrate, wherein a total or partial portion of the zinc is ionized in a vacuum atmosphere of 1×10?4 Torr or less and is introduced to the surface of the substrate to grow the ZnO based semiconductor crystal. As a result, it is possible to provide a method of producing a zinc oxide based semiconductor crystal capable of growing a zinc oxide semiconductor crystal having excellent surface flatness and crystallinity and including an extremely small amount of impurities at a high growth rate.

Abstract: Indole alkaloid derivatives having an opioid receptor agonistic effect, their synthesis, and therapeutic compositions containing these derivatives, and methods of treating conditions with these compounds and therapeutic compositions, are provided.

Abstract: The present invention provides an antenna that is small in size and has band frequencies corresponding to multibands, and a wireless communication apparatus including the antenna. The antenna according to the present invention has two radiation elements 12a and 12b connected to a ground plate 11 via a shorting pin. The two radiation elements 12a and 12b each have a lower arm and an upper arm that are formed through bending. The lower arm is connected to the shorting pin and is located closer to the ground plate 11 than the upper arm is. At least one of the lower arm and the upper arm has a meandered structure.

Abstract: A process for producing polymer particles having an antigen or an antibody introduced into the surface thereof, by carrying out miniemulsion polymerization using a monomer, a radical polymerization initiator, an emulsifier, and a hydrophobe in the presence of the antigen or antibody to thereby produce the polymer particles, is disclosed. According to the process, it is possible to provide a reagent for immunological analysis having an excellent detection sensitivity and capable of avoiding a nonspecific reaction which occurs in conventional methods.

Abstract: A method of treating or reducing at least one inflammatory condition or the susceptibility to at least one inflammatory condition is provided involving administering at least one CD69 antagonist to a subject, wherein the subject has been diagnosed with at least one inflammatory condition, or a susceptibility to the same. CD69 antagonists can include one or more of an anti-CD69 antibody, an anti-CD69 aptamer, a CD69 mRNA antagonist, and a small molecule pharmaceutical.

Abstract: A vector developed to transform fungi can be used to study the expression of a gene of interest. The vector can provide for the expression of signal proteins in fungi that can be observed and/or monitored. The vector can be used to investigate the effects of RNA interference on a gene of interest in pathogenic fungi. Systems and methods of using the vector are provided.

Abstract: A surface acoustic wave device includes a pair of reflectors and an interdigital transducer having a cross electrode having a interdigitated portion and a dummy portion and a dummy electrode. The dummy electrode has a length different from the length of the dummy portion of the cross electrode arranged adjacent to the dummy electrode.

Abstract: [PROBLEM TO BE SOLVED] An object of the present invention is to provide a novel tumor marker and use thereof. In more detail, the present invention provides a novel tumor marker, a method for measuring said tumor marker and a measurement kit, a method for detecting cancer using the same, a kit for detecting cancer, a method for screening a preventive and/or therapeutic agent for cancer, as well as a medicament such as cancer vaccine. [SOLUTION] According to the present invention, a method for measuring an alternative splicing variant of OATP1B3 mRNA in a sample to be examined is provided. Said measurement method comprises measuring mRNA comprising a nucleotide sequence represented by SEQ ID NO: 1 in the sequence listing table in a sample to be examined isolated from living organism with differentiation from a mRNA comprising a nucleotide sequence represented by SEQ ID NO: 2. Said measurement method is useful for detecting cancer or screening a preventive and/or therapeutic agent. [SELECTED DRAWING] FIG. 5.

Abstract: Disclosed is a process of preparing an optically active allyl compound, e.g., as represented by formula (III): comprising asymmetrically coupling an allyl compound with an organic nucleophilic compound in the presence of a catalyst. The catalyst is preferably a transition metal complex compound having a phosphine ligand. The phosphine ligand is preferably a 2,3-bis(dialkylphosphino)pyrazine derivative. The pyrazine derivative is preferably a quinoxaline derivative. The transition metal is preferably palladium.

Abstract: Disclosed are: a polypeptide marker for diagnosing arteriosclerosis; a gene marker for diagnosing arteriosclerosis; an antibody; a probe for detecting an arteriosclerosis marker gene; a DNA microarray or a DNA chip for detecting an arteriosclerosis marker gene; a method for detecting arteriosclerosis; and a kit for diagnosing arteriosclerosis; with which an arteriosclerotic lesion can be detected with much improved accuracy.

Abstract: An electrophoretic liquid includes a first electrophoretic particle, a second electrophoretic particle having a polarity opposite to that of the first electrophoretic particle, a non-electrophoretic particle, and a transparent dispersion medium. In the electrophoretic liquid, the first, second, and non-electrophoretic particles are dispersed in the transparent dispersion medium.

Abstract: The present invention provides a new additional identification of a gene related to cancer expression and a diagnostic kit using the same.