Abstract: The present invention relates to oral effervescent dosage forms for the administrations of an intended ingredient to children, and processes for their administration.
Type:
Grant
Filed:
August 26, 1991
Date of Patent:
June 29, 1993
Assignee:
Cima Labs, Inc.
Inventors:
Fred Wehling, Steve Schuehle, Navayanarao Madamala
Abstract: A tableting aid including magnesium carbonate and an oil adsorbed thereon provides useful lubricating and disintegration properties. A free-flowing particulate flavoring additive including magnesium carbonate and a flavor oil adsorbed thereon, is also described.
Type:
Grant
Filed:
March 11, 1991
Date of Patent:
June 15, 1993
Assignee:
Cima Labs. Inc.
Inventors:
Fred Wehling, Steve Schuehle, Navayanarao Madamala
Abstract: A pharmaceutical dosage form incorporates microparticles which are susceptible to rupture upon chewing or which are adapted to provide substantially immediate release of the pharmaceutical ingredient contained in the microparticles. These microparticles are provided in a tablet with an effervescent disintegration agent. When the tablet is taken orally, the effervescent disintegration agent aids in rapid dissolution of the tablet and hence permits release of the microparticles, and swallowing of the microparticles, before the pharmaceutical ingredient is released from the microparticles. The system therefore provides particularly effective taste masking.
Type:
Grant
Filed:
April 16, 1992
Date of Patent:
January 12, 1993
Assignee:
Cima Labs, Inc.
Inventors:
Fred Wehling, Steve Schuehle, Navayanarao Madamala