Patents Assigned to Closure Medical Corporation
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Patent number: 8153743Abstract: An adhesive composition includes one or more polymerizable cyanoacrylate monomers, a polymerization initiator and a polymerization accelerator for the one or more polymerizable cyanoacrylate monomers. A system for treating living tissue includes a first reservoir containing one or more polymerizable cyanoacrylate monomers, a second reservoir in a non-contacting relationship with the first reservoir containing a polymerization initiator and accelerator for the one or more polymerizable cyanoacrylate monomers, and an applicator capable of combining the polymerizable cyanoacrylate monomer and the polymerization initiator and accelerator to form an adhesive composition and then applying the adhesive composition to living tissue. The initiator may be a quaternary ammonium salt, and the accelerator may be a trihydroxy tertiary amine.Type: GrantFiled: July 31, 2008Date of Patent: April 10, 2012Assignee: Closure Medical CorporationInventors: Ibraheem T. Badejo, Andres Rivera, Melanie Vander Klok
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Patent number: 8118508Abstract: An applicator device for dispensing a polymerizable adhesive material comprising a body portion comprising a closed proximal end and an open distal end providing a cavity sized to accept a frangible container having a polymerizable adhesive material; at least one breaking member at least partially deflectable into the cavity; an annular housing movable with respect to the body portion; and a reservoir secured to the open distal end of the body portion, the reservoir further comprising an applicator; wherein the annular housing is movable relative to the body portion from a first position to a second position to deflect at least a portion of the breaking member into the cavity.Type: GrantFiled: November 30, 2006Date of Patent: February 21, 2012Assignee: Closure Medical CorporationInventors: Jack Goodman, Gregory Hake, Thomas Schoon, Thomas A. Shepard
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Publication number: 20090270884Abstract: A mesh dispensing device includes a housing having a substantially enclosed interior and an opening; a plurality of routing guide elements mounted in the interior of the housing; and a closed loop of backing film having a defined circumference. The closed loop of backing film is routed around at least a portion of the plurality of routing guide elements to define a path along which the closed loop of backing film moves. The device also includes a defined length of mesh that is detachably adhered to the closed loop of backing film and an opening guide element mounted near the opening of the housing. The opening guide element receives mesh that has been detached from the closed loop of backing film for dispensing.Type: ApplicationFiled: April 25, 2008Publication date: October 29, 2009Applicant: CLOSURE MEDICAL CORPORATIONInventor: Gregory HAKE
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Publication number: 20080302487Abstract: A dispensing device configured to operate with an adhesive backed mesh and backing film for tissue bonding is disclosed. The dispensing device provides for low-friction, low force pay-out of a desired length of an adhesive backed mesh to a wound site. The device prevents or eliminates distortion of the mesh prior to application to the wound sites and includes means for reducing or eliminating binding during use. The dispensing device is configured to operate in a “forward” mode (substrate to which mesh is applied passes beneath applicator after mesh is applied) to provide essentially an unobstructed view of the wound site during use.Type: ApplicationFiled: June 7, 2007Publication date: December 11, 2008Applicant: CLOSURE MEDICAL CORPORATIONInventors: Jack GOODMAN, Gregory HAKE, Thomas SCHOON
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Publication number: 20080255610Abstract: An article, such as a tissue bonding article, includes a flexible material, a polymerization initiator or rate modifier disposed in or on the flexible material, and a polymerizable adhesive composition permeated throughout at least a portion of the flexible material, where the polymerization initiator or rate modifier is a polymerization initiator or rate modifier for the polymerizable adhesive composition.Type: ApplicationFiled: June 27, 2008Publication date: October 16, 2008Applicant: Closure Medical CorporationInventors: Jerry Jonn, Julian Quintero, Glenn Hoskin, Susan L. Roweton
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Publication number: 20080241249Abstract: An adhesive composite composition is provided including one or more polymerizable monomers and one or more metal stearates. The one or more polymerizable monomers may be a cyanoacrylate monomer. The adhesive composite composition may further comprise a plasticizer, an initiator, a rate modifier, a stabilizer, a colorant, a heat dissipating agent, or other additives. Methods for the application of the adhesive composite compositions to living tissue are also provided. The adhesive composite composition provides an adhesive composite material upon polymerization which is a polymer matrix entrapping the metal stearate. Polymerization of the adhesive composite composition at a site on living tissue provides an adhesive composite material which promotes microcirculation and tissue growth at the site of application of the adhesive composite composition.Type: ApplicationFiled: March 30, 2007Publication date: October 2, 2008Applicant: Closure Medical CorporationInventors: Julian A. Quintero, Jerry Y. Jonn
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Publication number: 20080243082Abstract: Devices, systems and methods for fixation of medical articles which remain in a patient's body for a period of time are provided. The articles may be secured to the patient's skin by use of a device having an arcuate channel for holding the medical article. In one device, a base member including an arcuate channel receives the medical article, which base member has a plurality of protrusions which rest against the skin providing a gap for application of a polymerizable adhesive composition which polymerizes, forming a seal around the medical article and securing the medical article to the body. Alternatively, a device including a base member having an arcuate channel is provided adhered to a flexible member. The device receives the medical article and is positioned proximate to the patient's skin. Polymerizable adhesive composition is applied to the flexible member, securing the medical article to the patient's body upon polymerization.Type: ApplicationFiled: March 30, 2007Publication date: October 2, 2008Applicant: Closure Medical CorporationInventor: Jack Goodman
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Patent number: 7371345Abstract: Adhesive compositions, particularly medical adhesive compositions, often include several components that may react differently to different sterilization processes, particularly when combined with one another. The present invention is directed to methods of sterilizing different components or groups of components of a final adhesive composition. The different components or groups of components may be sterilized in separate containers before packaging the components or groups of components within a kit, and thereafter sterilizing the kit.Type: GrantFiled: December 23, 2002Date of Patent: May 13, 2008Assignee: Closure Medical CorporationInventors: Ubonwan A. Stewart, Melanie Vander Klok
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Publication number: 20080058863Abstract: An applicator/dispenser assembly for dispensing and/or applying an adhesive material comprises: a first body portion and a second body portion, at least one of the first and second body portions being movable relative to the other of the first and second body portions; a cavity in at least one of the first and second body portions; and a piercing or breaking member arranged on one of the first and second body portions. Movement of one of the first and second body portions relative to the other of the first and second body portions moves the piercing or breaking member into the cavity. When a container of adhesive material is at least partially disposed within the cavity, movement of one of the first and second body portions relative to the other moves the piercing or breaking member to rupture the container for dispensing and/or applying the adhesive material.Type: ApplicationFiled: October 30, 2007Publication date: March 6, 2008Applicant: Closure Medical CorporationInventors: Julian QUINTERO, Jerry Jonn, Jack Goodman, Daniel Hedgpeth, William Cotter
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Patent number: 7331463Abstract: A medical procedure kit includes a saleable package including: an outer wrap defining at least one sealed and sterile interior portion; at least one sterilized surgical tool located within the at least one interior portion and sterilized after insertion into the at least one interior portion by a sterilization process that sterilizes both the at least one interior portion and the at least one sterilized surgical tool; a container having a medical adhesive therein, wherein the adhesive is also sterilized; and a medical adhesive applicator for applying the medical adhesive, wherein the at least one sterilized surgical tool forms part of a wound closure system.Type: GrantFiled: December 6, 2004Date of Patent: February 19, 2008Assignee: Closure Medical CorporationInventor: Timothy Hickey
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Patent number: 7318937Abstract: Liquid coating compositions are provided that comprise siloxane containing polymer, volatile polydimethylsiloxane, and aliphatic hydrocarbon. The liquid coating compositions preferably comprise from 18-55 weight % of volatile polydimethylsiloxane, from 5-55 weight % of aliphatic hydrocarbon, from 1-40 weight % of siloxane containing polymer, and from 0-15 weight % of adjuvant.Type: GrantFiled: March 18, 2005Date of Patent: January 15, 2008Assignee: Closure Medical CorporationInventors: Jerry Y. Jonn, Brian McCrum, Wendy Su, Teresa Warren, Ibraheem T. Badejo
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Patent number: 7306390Abstract: An applicator/dispenser assembly for dispensing and/or applying an adhesive material comprises: a first body portion and a second body portion, at least one of the first and second body portions being movable relative to the other of the first and second body portions; a cavity in at least one of the first and second body portions; and a piercing or breaking member arranged on one of the first and second body portions. Movement of one of the first and second body portions relative to the other of the first and second body portions moves the piercing or breaking member into the cavity. When a container of adhesive material is at least partially disposed within the cavity, movement of one of the first and second body portions relative to the other moves the piercing or breaking member to rupture the container for dispensing and/or applying the adhesive material.Type: GrantFiled: September 17, 2003Date of Patent: December 11, 2007Assignee: Closure Medical CorporationInventors: Julian A. Quintero, Jerry Y. Jonn, Jack Goodman, Daniel L. Hedgpeth, William M. Cotter
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Patent number: 7255874Abstract: Biocompatible polymers and adhesives have a cyanoacrylic core and other substituents such as therapeutic agents, targeting moieties, imaging agents, amino acid residues or other organic moieties. Exemplary uses of inventive compositions include use as sealants and adhesives for medical uses, and as polymeric formulations for biocompatible implants and matrices and drug delivery.Type: GrantFiled: December 21, 2001Date of Patent: August 14, 2007Assignee: Closure Medical CorporationInventors: John S. Bobo, Julian A. Quintero, Jerry Y. Jonn, Joe B. Barefoot, Jeffrey G. Clark, Upvan Narang, Scott Marc Cannizaro, J. Christopher Marmo
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Publication number: 20060049203Abstract: An applicator/dispenser for dispensing, mixing and/or applying a polymerizable monomeric adhesive or sealant material comprises: a body portion; an actuator movable relative to the body portion; a cavity in the body portion; and a piercing or breaking portion on the actuator. Movement of the actuator relative to the body portion moves the piercing or breaking portion into the cavity. When a container of adhesive or sealant material is at least partially disposed within the cavity, movement of the actuator relative to the body portion moves the piercing or breaking portion to rupture the container for mixing, dispensing and/or applying the adhesive or sealant material.Type: ApplicationFiled: September 3, 2004Publication date: March 9, 2006Applicant: CLOSURE MEDICAL CORPORATIONInventors: Eric Boone, Keith D'Alessio, John Goodman, Scott Keplinger, Anthony Voiers, Daniel Tomko, William Johnson
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Publication number: 20060009099Abstract: An article, such as a tissue bonding article, includes a flexible material, a polymerization initiator or rate modifier disposed in or on the flexible material, and a polymerizable adhesive composition permeated throughout at least a portion of the flexible material, where the polymerization initiator or rate modifier is a polymerization initiator or rate modifier for the polymerizable adhesive composition.Type: ApplicationFiled: July 12, 2004Publication date: January 12, 2006Applicant: CLOSURE MEDICAL CORPORATIONInventors: Jerry Jonn, Julian Quintero, Glenn Hoskin, Susan Roweton
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Patent number: D540470Type: GrantFiled: September 3, 2004Date of Patent: April 10, 2007Assignee: Closure Medical CorporationInventors: Eric J. Boone, Gardner J. Klaasen
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Patent number: D559385Type: GrantFiled: January 2, 2007Date of Patent: January 8, 2008Assignee: Closure Medical CorporationInventors: Eric J. Boone, Gardner J. Klaasen
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Patent number: D570227Type: GrantFiled: September 1, 2006Date of Patent: June 3, 2008Assignee: Closure Medical CorporationInventors: Jack Goodman, Nathaniel R. Hallee
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Patent number: D573710Type: GrantFiled: November 30, 2006Date of Patent: July 22, 2008Assignee: Closure Medical CorporationInventors: Jack Goodman, Gregory Hake, Thomas Schoon, Thomas A. Shepard
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Patent number: D584815Type: GrantFiled: June 18, 2008Date of Patent: January 13, 2009Assignee: Closure Medical CorporationInventors: Jack Goodman, Gregory Hake, Thomas Schoon, Thomas A. Shepard