Abstract: The present invention is directed to aqueous solid state electrolytes that comprise a fluoride additive to stabilize the interface between the anode and aqueous electrolyte. The present invention is also directed to methods of making the solid state electrolyte materials and methods of using the solid state electrolyte materials in batteries and other electrochemical technologies.

Abstract: Arrays of single molecules and methods of producing an array of single molecules are described. Arrays with defined volumes between 10 attoliters and 50 picoliters enable single molecule detection and quantitation.

Abstract: Certain examples described herein enable a robotic device to accurate map a surrounding environment. The robotic device uses an image capture device and at least one of the image capture device and the robotic device move within the environment. Measurements associated with movement of at least one of the image capture device and the robotic device are used to determine a state of the robotic device. The state of the robotic device models the image capture device and the robotic device with respect to a model of the environment that is constructed by a mapping engine. By comparing the state of the robotic device with a measured change in the robotic device, an accurate representation of the state of the robotic device may be constructed. This state is used by the mapping engine to update the model of the environment.

Abstract: A propulsion control device of a 3D printing-based tunnel boring machine, includes two propulsion control modules, and each of which includes tunnel support assemblies, a propulsion control assembly and a barrel body, where a propulsion sliding sleeve is arranged on an outer surface, and several tunnel support assemblies are arranged on an outer side of each propulsion sliding sleeve. Support plates on the two propulsion control modules alternately rise to support a 3D printed tunnel pipe. In the propulsion control module with the support plates in a closed state, a propulsion hydraulic cylinder controls a propulsion hydraulic cylinder extending end to contract, so as to pull the propulsion sliding sleeve to a front section of the barrel body; and in the propulsion control module with the support plates in a support state, the barrel body continuously advances relative to the propulsion sliding sleeve.

Abstract: The herbicide-tolerant rice cultivar designated ‘PVL02’ and its hybrids and derivatives are disclosed.

Abstract: An antiviral agent is provided, having a phosphorodiamidate morpholino oligomer with an antisense sequence to a portion of a genome of a strain of Zika virus (ZIKV). The antiviral agent finds many uses, such as in a pharmaceutical composition, a method of treating ZIKV-mediated disease, a method of preventing ZIKV-mediated disease, a method of reducing or preventing the replication of ZIKV in a host cell, a method of controlling the spread of ZIKV in donated tissue, a treated tissue sample, and in the manufacture of a medicament for the treatment or prevention or ZIKV-mediated disease.

Abstract: A quantum Hall resistance apparatus is to improve resistance standards and includes a substrate, a graphene epitaxially grown on the substrate and having a plurality of first contact patterns at edges of the graphene, a plurality of contacts, each including a second contact pattern and configured to connect to a corresponding first contact pattern, and a protective layer configured to protect the graphene and to increase adherence between the first contact patterns and the second contact patterns. The contacts become a superconductor at a temperature lower than or equal to a predetermined temperature and under up to a predetermined magnetic flux density.

Abstract: A system and method are provided for analysing a functional magnetic resonance imaging (MRI) scan representing a time-sequence, comprising t time points, of images comprising v voxels, where each scan can be represented by a data matrix X?t×v. The method comprises modelling the scan data X as the convolution of neural activation time courses N?+t×v and a haemodynamic filter ?, and performing an inverse operation to estimate N from X and ?. The method further compasses decomposing the neural activation time courses N into multiple brain network components by representing N as the product of a first matrix H defining, for each component, a spatial map of the voxels belonging to that component, and a second matrix W defining, for each component, the time sequence of activation of that component during the scan. In other implementations, the matrix decomposition may be performed before the deconvolution.

Abstract: A single-antenna device includes a single antenna, at least one processor, and at least one memory. The single-antenna device is operable to receive a signal including at least one frame. Each of said frame includes a repeating portion. The single-antenna device determines a difference of phase and amplitude of the repeating portion and further determines whether the signal is transmitted from a trusted source based at least in part on the difference of phase and amplitude of the repeating portion.

Abstract: Cesium-niobium-chalcogenide compounds and a semiconductor device are provided. The cesium-niobium-chalcogenide compound is selected from the group consisting of CsNbS3, CsNbSe3, and CsNbOx-3Qx, where Q is S or Se, and x is 1 or 2, and includes an edge-shared orthorhombic crystal structure. In one embodiment, the semiconductor device includes a cathode layer, an anode layer, and an active layer disposed between the cathode layer and the anode layer, and the active layer includes the cesium-niobium-chalcogenide compound.

Abstract: Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.

Abstract: A method for predicting risk of recurrence of cancer in an individual with cancer, the method comprising a step of assaying a cancer sample from the individual for positive expression of at least two genes or proteins encoded by those genes selected from the group consisting of FOXM1, UHRF1, PTTG1, E2F1, MYBL2, HMGB2, ATAD2, E2F8, ZNF367 and TCF19, wherein positive expression of the at least two genes correlates with increased risk of recurrence of cancer compared with an individual who does not exhibit positive expression of the at least two genes or proteins encoded by those genes.

Abstract: The present invention relates to the therapeutic uses of compositions containing antibody molecules and functional fragments thereof, e.g antibody molecules and functional fragments capable of binding to tumor necrosis factor alpha (TNF?), in the topical treatment of inflammatory bowel diseases, including Crohn's disease and ulcerative colitis.

Abstract: The present disclosure relates to a viral vector suitable for introducing a therapeutic agent, such as a peptide, protein or small RNA, into a host or otherwise treating a host. The vector may include an exogenous RNA segment with a hairpin-like structure or having two or more base-paired regions separated by one or more non-base-paired regions. The exogenous RNA segment may have a secondary structure, minimum free energy, average positional entropy or other attributes within specified ranges, or with values similar to one or more hairpin-like structures of a reference wild type virus. Optionally, the RNA vector may be derived from the reference wild type virus or a relative of the reference wild type virus. In some examples, the vector is capable of capable of systemic and phloem-limited movement and replication within a host plant. In some examples, the reference wild type virus is an umbravirus-like associated RNA.

Abstract: The invention provides a supramolecular polymer composition capable of co-assembly to maintain a three dimensional (3-D) macrostructural form after 3-D printing, made of a solvent, a template molecule; and a reactive component. The reactive component can be at least one monomer that is capable of hydrogen bonding with the template molecule to form a 1D supramolecular structure. The template may be an amphiphilic polymer. The monomer has at least two pendant groups capable of covalent crosslinking. The invention also includes a 3-D structure formed by crosslinking a 3-D printed supramolecular polymer composition, which optionally has a mesoporous structure. Also included is a method of manufacturing a 3-D structure by delivering a supramolecular polymer composition onto a surface of a substrate to form the 3-D structure.

Abstract: The present disclosure relates to a viral vector suitable for introducing a therapeutic agent, such as a peptide, protein or small RNA, into a host or otherwise treating a host. The vector may include an exogenous RNA segment with a hairpin-like structure or having two or more base-paired regions separated by one or more non-base-paired regions. The exogenous RNA segment may have a secondary structure, minimum free energy, average positional entropy or other attributes within specified ranges, or with values similar to one or more hairpin-like structures of a reference wild type virus. Optionally, the RNA vector may be derived from the reference wild type virus or a relative of the reference wild type virus. In some examples, the vector is capable of capable of systemic and phloem-limited movement and replication within a host plant. In some examples, the reference wild type virus is an umbravirus-like associated RNA.

Abstract: Embodiments described provide an ultrasound method, and an ultrasound apparatus and computer program product operable to perform that method. In some embodiments, the method allows for provision of a multi-transducer ultrasound imaging system by providing a robust method to accurately localize the transducers in the system in order to beamform a final image. The method and apparatus described allow for improvements in imaging quality in terms of resolution, depth penetration, contrast and signal to noise ratio (SNR).

Abstract: Devices and methods are disclosed for remote clinical monitoring performance of exercises using an instrumented resistance device (100). An example device (100) includes a resistance band (120) having a first end (122) and a second end (124). A first handle (130) connected to the first end (122) and a second handle (140) connected to the second end (124) of the resistance band (120). The device (100) further includes a force sensing assembly (150) positioned between the first handle (130) and the first end (122). The force sensing assembly (150) includes a force sensor (156) connected to the resistance band (120), a microcontroller (182) connected to the force sensor (156) to receive a set of load force measurements from the force sensor (156), and a communication module (184) connected to the microcontroller (182) to transmit the set of load force measurements to a local data receiving device (170).

Abstract: T cell receptor (TCR) diversity of a subject, including TCR diversity in CD8+ T cell subsets, is used as a predictive indicator of responsiveness of the subject to cancer immunotherapy prior to initiation of the immunotherapy. Exemplified immunotherapy comprises administering an immune checkpoint inhibitor to a subject, wherein a TCR diversity value in CD8+ T cell subsets from the subject, such as CD8+ T cell subpopulations defined by differential cell surface marker expression, is higher than a reference value.

Abstract: The present disclosure provides a bifunctional linker for coupling at least one functional moiety, preferably a bis-allyl propionic acid (BAPA), to a polymer-containing matrix. Also disclosed by the present disclosure are anhydrides of the bifunctional linker, processes for preparing the bifunctional linker and such anhydride, as well as surfaces, such as cellulose containing matrices, coupled with the bifunctional linker, at times, the latter carrying a functional agent.