Abstract: A neuron circuit performing synapse learning on weight values includes a first sub-circuit, a second sub-circuit, and a third sub-circuit. The first sub-circuit is configured to receive an input signal from a pre-synaptic neuron circuit and determine whether the received input signal is an active signal having an active synapse value. The second sub-circuit is configured to compare a first cumulative reception counter of active input signals with a learning threshold value based on results of the determination. The third sub-circuit is configured to perform a potentiating learning process based on a first probability value to set a synaptic weight value of at least one previously received input signal to an active value, upon the first cumulative reception counter reaching the learning threshold value, and perform a depressing learning process based on a second probability value to set each of the synaptic weight values to an inactive value.

Abstract: A gamma ray Compton TOF camera system includes multiple detector modules, each comprising a gamma radiation sensitive material and arranged in layers formed by one or more detector modules. The layers are placed such that they interfere an incoming gamma ray in order to completely or partially absorb it after one or more Compton interactions and are spatially separated in order to allow for the determination of the temporal order of each gamma ray interaction inside the camera system. The camera system also includes read out electronics and a Data Acquisition System where signals from the detector modules will be readout, digitized and sent to a processing unit, which is capable to obtain the 3D position, energy and temporal sequential order of the individual interactions produced by a single incident gamma ray.

Abstract: The invention relates to a spectrophotometer, especially a spectrophotometer that can carry out simultaneous analysis at different points on the same sample (4), with a high spatial resolution and without requiring a mechanical system for physical scanning along the sample. This is obtained by the provision of means for processing the light received by the photodetectors (5), said processing means having a correlation wherein each of the photodetectors (5) corresponds to a spatial point on the sample (4). In the case of dark field applications, the present invention ensures the standardization of the data using the same measure.

Abstract: The present disclosure concerns an electrolyte suitable for calcium-based secondary cells, comprising calcium ions and an electrolyte medium, wherein the electrolyte is not solid at standard conditions and wherein the electrolyte medium includes at least two distinct non-aqueous solvents.

Abstract: The present invention relates to an antioxidant ingredient with low calorie content obtainable by a process that comprises the following steps: (a) selecting as raw material at least one fruit and/or plant material with high antioxidant content, greater than 6 g/100 g dry matter; (b) obtaining juice and pulp by means of grinding, squeezing and/or pressing the raw material; (c) extracting sugars from the pulp obtained in the preceding step in order to produce a pulp with low calorie content; (d) dehydrating the pulp by means of a method selected from air drying, low-temperature drying with application of vacuum and/or freeze-drying; and (e) milling the pulp in order to produce the antioxidant ingredient with low calorie content. Likewise, the invention relates to the process for obtaining said ingredient and to the use thereof for the production of functional foods.

Abstract: The present invention concerns an ion sensor based on differential measurement, that by means of at least two ion-sensitive field-effect transistors, compares the concentration of certain ions in a solution to be measured with the concentration of certain ions in a reference solution contained in a micro-reservoir with a micro-channel. To do this, the micro-reservoir and the micro-channel cover at least the gate of one of the ion-sensitive field-effect transistors and make up a unit partially filled with a porous material that covers the entirety of the aforementioned gate and at least the base of the micro-channel.

Abstract: There are disclosed nanoemulsion optical materials, methods of making nanoemulsion optical materials and optical articles comprising nanoemulsion optical materials. A nanoemulsion optical material includes a polymer matrix and a plurality of nano-droplets, comprising an optically interactive material, directly dispersed within the polymer matrix.

Abstract: This disclosure describes an imaging radiation detection module with novel configuration of the scintillator sensor allowing for simultaneous optimization of the two key parameters: detection efficiency and spatial resolution, that typically cannot be achieved. The disclosed device is also improving response uniformity across the whole detector module, and especially in the edge regions. This is achieved by constructing the scintillation modules as hybrid structures with continuous (also referred to as monolithic) scintillator plate(s) and pixelated scintillator array(s) that are optically coupled to each other and to the photodetector.

Abstract: The present invention describes a refractive multifocal intraocular lens with aspheric geometry on both surfaces in such a way that the map of local optical strength of the lens, combined with the cornea, has a central region of intermediate optical strength surrounded by a ring of maximum optical strength, with a smooth transition between the two, after which it alternates smoothly between rings of varying strengths.

Abstract: The invention relates to a catalytic activation layer for use in oxygen-permeable membranes, which can comprise at least one porous structure formed by interconnected ceramic oxide particles that conduct oxygen ions and electronic carriers, where the surface of said particles that is exposed to the pores is covered with nanoparticles made from a catalyst, the composition of which corresponds to the following formula: A1-x-yBxCyOR where: A can be selected from Ti, Zr, Hf, lanthanide metals and combinations thereof; B and C are metals selected from Al, Ga, Y, Se, B, Nb, Ta, V, Mo, W, Re, Mn, Sn, Pr, Sm, Tb, Yb, Lu and combinations of same; and A must always be different from B. 0.01<x<0.5; 0<y<0.3.

Abstract: A miniaturised instrument for simulating simultaneous vision by generating masks is provided with a single image-forming optical channel. The instrument comprises: a mask-generating element (EGM) which generates at least two complementary masks, with a temporal frequency of alternation such that when one partially blocks the incident light, the other allows the incident light to partially pass, and vice-versa; an adjustable lens (LA) of variable optical power which generates, with said frequency of alternation, at least two different optical powers corresponding to at least two observation distances. The EGM and the LA are located in a single optical channel via which the incident light circulates, such that each mask of the EGM is temporally synchronised with a power of the LA. The combination of all the masks and optical powers produces, via high-speed temporal fusion, a pupil pattern wherein at least two optical powers corresponding to at least two observation distances are combined.

Abstract: The present invention discloses a biosensor for visual detection of an analyte, based on the light to heat conversion properties of metal nanoparticles: the analyte is visually detected by the color change in the support areas (where the analyte is present), produced as a result of the heat generated by the metal nanoparticles where they are irradiated with an external light source. Use of said biosensor in a method for the detection of analytes is also claimed.

Abstract: The invention relates to a hybrid medical PET-SPECT/MR imaging device comprising at least one scintillating crystal and at least one module for detecting radiation which contains at least one matrix of photodetectors and an electronics section, such that said module has a mechanical structure, the external, internal or both surfaces of which are divided into at least two sections, of which at least one is coated in graphene, and the rest in non-ferromagnetic conductive material, or all the sections are coated in graphene, and such that the coating forms a Faraday cage. The invention also relates to a shielding against radiofrequency for a medical imaging device, comprising a graphene coating, which is continuous or in bands, on all the faces of the mechanical structure of the detection module of the device, or a graphene coating, continuous or in bands, on at least one face, combined with a coating of non-ferromagnetic conductive materials on the remaining faces, and said shielding forming a Faraday cage.

Abstract: The invention relates to a material comprising oligoglycine tectomers and nanowires. This material is useful as an electrode, as a conductive and transparent hybrid material, and as a pH sensor, as well as in biomedical applications.

Abstract: The present invention relates to the synthesis and application of gold catalysts supported in mixed CuO/ZnO/Al2O3 oxides prepared on the basis of their corresponding solids with a hydrotalcite structure as catalysts in the water-gas shift reaction, for use in fuel processors coupled to fuel cells.

Abstract: The invention relates to haptens, immunogens and secondary immunoreactive agents, to the use thereof for producing wide-spectrum antibodies against quinolone-type antibiotics, to the application thereof to immunochemical analysis techniques, and to a kit enabling the detection of said antibiotics in biological samples from food products of animal origin.

Abstract: A calcium-based secondary cell including, as a positive-electrode active material, a molybdenum oxide-based material containing molybdenum in an oxidation state of 4 or more and 6 or less.

Abstract: The present invention relates to the specific silencing of the ? (alpha), ? (beta), ? (gamma) and ? (omega)-gliadins of hard wheat for flour by RNA interference (RNAi) through employment of a polynucleotide which is transcribed into an hpRNA (hairpin RNA). Furthermore the present invention additionally relates to a vector, cell, plant or seed comprising the polynucleotide, the expression whereof is specifically directed in particular tissues of wheat seeds through gene expression-regulating sequences such as, for example, the promoter of a gene of ?-gliadins or the promoter of the gene encoding for a D-hordein.

Abstract: Process for obtaining fluoride-doped citrate-coated amorphous calcium phosphate nanoparticles. This material has applications in biomedicine due to its biodegradability and bioactivity; it also promotes cell adhesion and osteogeneration. In dentistry, it may be used in toothpastes, mouthwashes, chewing gums, gels and fluoride varnishes as a remineralising agent of dentine and enamel. It is based on two solutions formed by calcium chloride and sodium citrate on the one hand, and by sodium monohydrogenophosphate and sodium carbonate with a fluoride compound on the other, which are mixed at room temperature. The process is eco-efficient and eco-friendly, as it does not leave any acid residue; it consists of a single stage and it is the first time that an amorphous calcium phosphate coated with citrate and doped with fluoride, which enhances its remineralising action, is obtained.

Abstract: The invention relates to a method to predict the response to treatment with radiotherapy combined with cisplatin-based chemotherapy in patients with cancer, preferably non-microcytic lung cancer, wherein said method is based on the detection of the presence of methylation in the IGFBP-3 gene. The present invention also relates to an in vitro method to design a customised treatment for an individual with said disease. The method of the invention may be quantitative or semi-quantitative. The present invention also relates to a probe designed for the quantitative detection of the methylation of the IGFBP-3 gene, to a kit that comprises it and to the use of the kit to predict the response of a subject to the aforementioned treatment.