Patents Assigned to CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS
  • MODIFIED IMMUNIZATION VECTORS
    Publication number: 20200172926
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Application
    Filed: July 17, 2019
    Publication date: June 4, 2020
    Applicants: Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizo, Consejo Superior De Investigaciones Cientificas, IPPOX Foundation
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mario Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias El Haddad, James Tartaglia
  • Device for extracting three-dimensional information from X-ray images of an object, method for calibrating said device, and method for generating said X-ray images
    Patent number: 10672145
    Abstract: Device for extracting three-dimensional information from radiographic images of an object; process for calibrating said device; and process for generating said radiographic images includes an X-ray emitter and an X-ray sensor. A contour sensor represents contour points of an object by means of the radiation emitted or reflected by the object. The device also has a calibration framework with X-ray markers, and contour markers. The processes are based on taking contour and X-ray images of the calibration framework, first without an object of study and subsequently with one, taking into account the information provided by the markers, and the fact that the contour sensor is placed in the same manner with respect to the X-ray emitter in all the images taken.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: June 2, 2020
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), UNIVERSITAT DE VALENCIA
    Inventors: Francisco Javier Albiol Colomer, Alberto Corbi Bellot, Celso Bellot Romero, Alberto Albiol Colomer
  • Method for obtaining the absorption position, mass and rigidity of a particle
    Patent number: 10670447
    Abstract: A method for obtaining the absorption position, mass and rigidity of a particle deposited on the surface of a resonator based on the relative change in the resonance frequency of said resonator in 3 or 4 flexural vibration modes. The rigidity of the particles is of great interest in the study of cells and other biological compounds that change state without significantly changing the mass.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: June 2, 2020
    Assignees: NANODREAMS, S.L., CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Oscar Malvar Vidal, Jose Jaime Ruz Martinez, Priscila Monteiro Kosaka, Montserrat Calleja Gomez, Francisco Javier Tamayo De Miguel
  • METHOD AND APPARATUS FOR RECOVERING FIBERS EMBEDDED IN A COMPOSITE MATERIAL
    Publication number: 20200165525
    Abstract: A method for recovering fibers embedded in a composite material including loading a furnace chamber with a volume of the composite material; thermolyzing the composite material in the furnace chamber, resulting in a gaseous fraction that is continuously evacuated from the furnace chamber, and a residue of fibers covered with char that is left in the furnace chamber; cracking the gaseous fraction from the thermolyzing operation, resulting in a mixture of condensable and non-condensable gases that can be recycled; injecting a stream of an oxygen-containing gas into the still hot furnace chamber after the thermolyzing is completed therein, to burn the char from the fibers in an exothermic combustion.
    Type: Application
    Filed: June 1, 2018
    Publication date: May 28, 2020
    Applicants: THERMAL RECYCLING OF COMPOSITES, S.L., CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)
    Inventors: Roger GRAU GARCIA, Ferran GRAU GARCIA, Oriol GRAU GARCIA, Felix Antonio LOPEZ GOMEZ, Olga RODRIGUEZ LARGO
  • Method for the direct synthesis of Cu-containing silicoaluminate material with the AEI zeolite structure, and the catalytic applications thereof
    Patent number: 10646826
    Abstract: The present invention provides a new method for preparing the copper-containing silicoaluminate form of the AEI zeolite structure by means of a direct synthesis methodology. This new process involves combining a organometallic copper-complex with an additional organic molecule capable of directing the crystallization of the silicoaluminate form of the AEI zeolite structure as organic structure-directing agents (OSDAs).
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: May 12, 2020
    Assignees: Consejo Superior de Investigaciones Cientificas, Universitat Politècnica de València
    Inventors: Avelino Corma Canós, Manuel Moliner Marín, Nuria Martín García
  • Method for detecting circulating cells in superficial body fluids
    Patent number: 10639012
    Abstract: The present invention relates to a method for measuring circulating cells in superficial body fluids by means of high-frequency-based device. The method can be used for detecting circulating cells in the fluids of an individual without the necessity of extracting a sample of the individual, being useful as a diagnostic tool and for monitoring the effectiveness of a treatment administered to an individual suffering from a viral, protozoal, fungal and/or bacterial disease.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: May 5, 2020
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), FUNDACION PARA EL CONOCIMIENTO MADRI+D, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Luis Elvira Segura, Oscar Martinez Graullera, Shiva Kant Shukla, Francisco Montero, Javier Jimenez, Ian Richard Butterworth, Brian Anthony, John Lee Haeseon, Carlos Castro Gonzalez
  • Pradimicin derivatives for the treatment of diseases caused by kinetoplastids
    Patent number: 10610538
    Abstract: The present invention relates to a class of novel pradimicins and analogues and derivatives thereof, including the compounds of formula A, I and 111, and/or a pharmaceutical acceptable addition salt thereof and/or a stereoisomer thereof and/or a solvate thereof and their use to treat or prevent kinetoplastid infections and their use to manufacture a medicine to treat or prevent kinetoplastid infections, particularly infections with trypanosoma and leishmania, such as Trypanosoma brucei, Trypanosoma cruzi and Leischmania donovani. wherein Ra, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the claim 1 or as described in detail in the description of the invention. The present invention also relates to pharmaceutical compositions of said compounds and the use of said pharmaceutical compositions to treat or prevent kinetoplastid infections.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: April 7, 2020
    Assignees: Katholieke Universiteit Leuven, Consejo Superior de Investigaciones Científicas - CSIC
    Inventors: Jan Balzarini, Dolores González Pacanowska, Luis Miguel Ruiz Pérez, Victor Castillo Acosta, Yasuhiro Igarashi
  • Molybdenum-based electrode materials for rechargeable calcium batteries
    Patent number: 10608245
    Abstract: A calcium-based secondary cell including, as a positive-electrode active material, a molybdenum oxide-based material containing molybdenum in an oxidation state of 4 or more and 6 or less.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: March 31, 2020
    Assignees: TOYOTA MOTOR EUROPE, AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Fanny Barde, Maria Rosa Palacin, Alexandre Ponrouch, Maria Elena Arroyo de Dompablo
  • Molecular adjuvant and vaccine
    Patent number: 10568960
    Abstract: The invention relates to the fields of vaccines and vaccine adjuvants, and generally relates to polynucleotide adjuvants, polynucleotide vaccines and vaccine compositions. More specifically, the invention relates to said polynucleotides and vaccine compositions for use in inducing or enhancing a prophylactic or therapeutic immune response in a mammalian subject. Furthermore, it relates to said polynucleotides and vaccine compositions for use in the prophylactic or therapeutic treatment of an infectious disease, such as in the prophylactic or therapeutic treatment of leishmaniasis.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: February 25, 2020
    Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS
    Inventors: Pedro José Alcolea Alcolea, Ana María Alonso Ayala, Vincente Emilio Larraga Rodríguez De Vera
  • ION SENSOR BASED ON DIFFERENTIAL MEASUREMENT, AND PRODUCTION METHOD
    Publication number: 20200025710
    Abstract: Ion sensor based on differential measurement comprising an ISFTET-REFET pair wherein the REFET is defined by a structure composed of an ISFET covered by a microreservoir where an internal reference solution is contained. The sensor comprises a first and a second ion-selective field effect transistor, an electrode, a substrate on the surface whereof are integrated the two transistors, connection tracks and the electrode and a structure adhered on the first ion-selective field effect transistor which creates a microreservoir on the gate of said first transistor, with the microreservoir having a microchannel which connects the microreservoir with the exterior and the microreservoir being filled with the reference solution.
    Type: Application
    Filed: August 2, 2019
    Publication date: January 23, 2020
    Applicant: Consejo Superior de Investigaciones Cientifícas (CSIC)
    Inventors: Antoni BALDI COLL, Carlos DOMINGUEZ HORNA, Cecilia JIMENÉZ JORQUERA, César FERNÁNDEZ SÁNCHEZ, Andreu LLOBERA ADAN, Ángel MERLOS DOMINGO, Alfredo CADARSO BUSTO, Isabel BURDALLO BAUTISTA, Ferrán VERA GRAS
  • Dream neuronal calcium sensor-modulating compounds, and therapeutic uses thereof
    Patent number: 10526276
    Abstract: The present invention relates to a group of compounds with a structural nucleus derived from phenylacetamide, having the following formula (I): that can modulate the DREAM neuronal calcium sensor. Consequently, the present invention also relates to the use of these compounds for the treatment or prevention of disorders or diseases in which DREAM levels are above or below physiologically normal levels.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: January 7, 2020
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS, CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES NEURODEGENERATIVAS (CIBERNED), UNIVERSIDAD AUTÓNOMA DE MADRID
    Inventors: Marta Gutiérrez Rodríguez, Pilar Cercos Pita, María Rosario Herranz Herranz, María Teresa García López, María Carmen Valenzuela Miranda, José Ramón Naranjo Orovio, Britt Mellstrom, Paz González Pérez, María Mercedes Martín Martínez, José Manuel Dopazo Santos
  • Method for preparing the silicoaluminate form of the AEI zeolite structure with high yields, and its application in catalysis
    Patent number: 10526208
    Abstract: A synthesis process for a crystalline material with the AEI zeolite structure, comprising (i) preparation of a mixture containing, at least, water, one zeolite with the FAU crystal structure as the only source of silicon and aluminum, a cyclic ammonium cation with alkyl substituents as the OSDA, and a source of alkaline or alkaline-earth cations (A), wherein the synthesis mixture has the following molar composition: SiO2:a Al2O3:b OSDA:c A:d H2O where a ranges between 0.001 and 0.2; where b ranges between 0.01 and 2; where c ranges between 0 and 2; where d ranges between 1 and 200; and wherein the mixture is free from phosphorous and fluorinated species, (ii) crystallisation of the mixture and, (iii) recovery of the crystalline material. Also, preparation of catalysts based on the AEI zeolite and application as a catalysts in processes including the selective catalytic reduction of NOx.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: January 7, 2020
    Assignees: Consejo Superior de Investigaciones Cientificas, Universitat Politència de València
    Inventors: Avelino Corma Canós, Manuel Moliner Marín, Nuria Martín García
  • System for biodetection applications
    Patent number: 10502734
    Abstract: The present invention relates to a system for biodetection applications comprising two basic elements, a substrate with a functionalized surface and a nanoparticle, the system being capable of enhancing the plasmonic effect of the nanoparticle. The invention also relates to a biosensor incorporating such system, in addition to the method for detecting and quantifying a target analyte selected in a sample using such system. Finally, the invention relates to a device which can detect the enhanced optoplasmonic effect of the nanoparticles by means of the system of the invention or by combining the detection of such optoplasmonic effect with the analysis of the changes in the mechanical characteristics in the substrate.
    Type: Grant
    Filed: June 2, 2015
    Date of Patent: December 10, 2019
    Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Francisco Javier Tamayo de Miguel, Priscila Monteiro Kosaka, Valerio Pini, Montserrat Calleja Goméz, Jose Jaime Ruz Martinez, Daniel Ramos Vega, Maria Ujue Gonzalez Sagardoy
  • Synthesis of zeolite with the CHA crystal structure, synthesis process and use thereof for catalytic applications
    Patent number: 10486976
    Abstract: Disclosed is a synthesis process of a crystalline material with the CHA structure, which comprises the following steps: i) Preparation of a mixture that comprises one source of water, one source of a tetravalent element Y, one source of an alkaline or alkaline earth cation (A), one source of a trivalent element X, and one organic molecule (OSDA1) with the structure [R1R2R3R4N+]Q?, being the molar composition: n X2O3:YO2:a A:m OSDA1:z H2O, ii) crystallisation of the mixture obtained in i) in a reactor, iii) recovery of the crystalline material obtained in ii).
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: November 26, 2019
    Assignees: Consejo Superior de Investigaciones Cientificas, Universitat Politècnica de València
    Inventors: Avelino Corma Canós, Manuel Moliner Marín, Nuria Martín García
  • Synthesis of zeolite with the CHA crystal structure, synthesis process and use thereof for catalytic applications
    Patent number: 10486975
    Abstract: Disclosed is a synthesis process of a crystalline material with the CHA structure, which comprises the following steps: i) Preparation of a mixture that comprises one source of water, one source of a tetravalent element Y, one source of an alkaline or alkaline earth cation (A), one source of a trivalent element X, and one organic molecule (OSDA1) with the structure [R1R2R3R4N+]Q?, being the molar composition: n X2O3:YO2:a A:m OSDA1:z H2O, ii) crystallisation of the mixture obtained in i) in a reactor, iii) recovery of the crystalline material obtained in ii).
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: November 26, 2019
    Assignees: Consejo Superior de Investigaciones Científicas, Universitat Politècnica de València
    Inventors: Avelino Corma Canós, Manuel Moliner Marín, Nuria Martín García
  • Method, Digital Electronic Circuit and System for Unsupervised Detection of Repeating Patterns in a Series of Events
    Publication number: 20190340494
    Abstract: A method of performing unsupervised detection of repeating patterns in a series (TS) of events (E21, E12, E5 . . . ), comprising the steps of: a) Providing a plurality of neurons (NRI-NRP), each neuron being representative of W event types; b) Acquiring an input packet (IV) comprising N successive events of the series; c) Attributing to at least some neurons a potential value (PTI-PTP), representative of the number of common events between the input packet and the neuron; d) Modify the event types of neurons having a potential value exceeding a first threshold TL; and e) generating a first output signal (OSI-OSP) for all neurons having a potential value exceeding a second threshold TF, and a second output signal, different from the first one, for all other neurons. A digital electronic circuit and system configured for carrying out such a method.
    Type: Application
    Filed: May 20, 2019
    Publication date: November 7, 2019
    Applicants: CENTRE NATIONAL DE LA RECHERCHHE SCIENTIFIQUE, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Simon Thorpe, Timothée MASQUELIER, Jacob MARTIN, Amir Reza YOUSEFZADEH, Bernabe LINARES-BARRANCO
  • Sample and hold based temporal contrast vision sensor
    Patent number: 10469776
    Abstract: This invention relates to a pixel circuit comprising a photo-sensor stage comprising a photodiode delivering a photoreceptor current, a comparison stage configured for detecting a change in a signal voltage derived from said photoreceptor current, a sample-and-hold circuit connected to the converting stage and to the comparison stage, said comparison stage configured to output an input signal for the sample-and-hold circuit, and for emitting a sampling signal to a control terminal of the sample-and-hold circuit when a change is detected in the signal voltage.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: November 5, 2019
    Assignees: Prophesee, Consejo Superior de Investigaciones Cientificas
    Inventors: Thomas Finateu, Bernabe Linares Barranco, Teresa Serrano Gotarredona, Christoph Posch
  • Calcium-based secondary cell and battery comprising the same
    Patent number: 10461362
    Abstract: A calcium-based secondary cell including a negative electrode that includes a negative-electrode active material, a positive electrode that includes a positive-electrode active material, an electrolyte arranged between the negative electrode and the positive electrode, and a temperature control element. The negative-electrode active material is capable of accepting and releasing calcium ions, and the positive-electrode active material is capable of accepting and releasing calcium ions. The electrolyte includes calcium ions and an electrolyte medium, and is not solid at a temperature of about 20° C. and a pressure of about 1 atm. The electrolyte medium includes a non-aqueous solvent.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: October 29, 2019
    Assignees: TOYOTA MOTOR EUROPE, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Fanny Barde, Rosa Palacin, Alexandre Ponrouch
  • Selective modulators of the activity of the GPR55 receptor: chromenopyrazole derivatives
    Patent number: 10435412
    Abstract: The present invention relates to a family of chromenopyrazole derivatives of formula (I): which have the ability to modulate the receptor of the cannabinoid family GPR55, whereby the invention also relates to the use of these compounds for the manufacture of a medicament for the treatment of diseases in which the GPR55 receptor has a physiological role such as diabetes, Parkinson's disease, multiple sclerosis, neuropathic pain, osteoporosis and cancers such as cholangiocarcinoma, breast cancer, ovarian and prostate cancer, glioblastoma, and cutaneous carcinoma.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: October 8, 2019
    Assignees: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
    Inventors: Nadine Jagerovic, Paula Morales Lazaro, Ruth Ross, Lauren Whyte
  • Ion sensor based on differential measurement, and production method
    Patent number: 10436743
    Abstract: Ion sensor based on differential measurement comprising an ISFTET-REFET pair wherein the REFET is defined by a structure composed of an ISFET covered by a microreservoir where an internal reference solution is contained. The sensor comprises a first and a second ion-selective field effect transistor, an electrode, a substrate on the surface whereof are integrated the two transistors, connection tracks and the electrode and a structure adhered on the first ion-selective field effect transistor which creates a microreservoir on the gate of said first transistor, with the microreservoir having a microchannel which connects the microreservoir with the exterior and the microreservoir being filled with the reference solution.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: October 8, 2019
    Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFÍCAS
    Inventors: Antoni Baldi Coll, Carlos Dominguez Horna, Cecilia Jimenèz Jorquera, César Fernández Sánchez, Andreu Llobera Adan, Ángel Merlos Domingo, Alfredo Cadarso Busto, Isabel Burdallo Bautista, Ferrán Vera Gras