Patents Assigned to Consejo Superior de Investigaciones Cientificas (CSIC)
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Patent number: 8440814Abstract: The invention relates to a compound corresponding to general formula (I) wherein n is a whole number from 1-6, m is a whole number equal to 5, 6 or 7, R1 is an OH group, all R1 s are identical, Z is an NHX group, X is a hydrogen atom, and R is a hydrogen atom or a bioidentification element, with the proviso that the compound wherein n=1, m=6, Z=NH2 and R1=OH is excluded.Type: GrantFiled: May 19, 2009Date of Patent: May 14, 2013Assignees: Centre National de la Recherche Scientifique, Universite Joseph Fourier, Consejo Superior de Investigaciones Cientificas (CSIC), Universidad de SevillaInventors: Jacques Defaye, Carmen Ortiz-Mellet, Jose Manuel Garcia-Fernandez, Maria Gomez-Garcia, Kazimierz Chmurski, Jian-Xin Yu
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Publication number: 20130104597Abstract: A helium recovery plant adapted to filter, compress, and purify helium gas collected from one or more helium-using instruments, as well as to liquefy and redistribute the purified gas within a closed system. The recovery plant is adapted to match the purification and liquefaction rate of the system with the consumption rate of the coupled instruments. Additionally, the recovery plant is adapted to match the liquefaction rate of a liquefaction module with a boil-off rate of liquid helium within a Dewar thereof. The recovery plant is further adapted to recycle helium therein in an effort to achieve zero loss.Type: ApplicationFiled: April 20, 2012Publication date: May 2, 2013Applicants: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), GWR INSTRUMENTS, INC., UNIVERSIDAD DE ZARAGOZAInventors: Conrado RILLO MILLÁN, Leticia TOCADO MARTÍNEZ
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Publication number: 20130108686Abstract: The invention relates to a method for obtaining formulations which improve the binding capacity of siRNAs in relation to plasma components, which promote the transport of siRNA in the blood, which increase the passage of siRNA through the cell membrane and, consequently, which increase the inhibitory activity of siRNA. The invention also relates to a method for obtaining a formulation comprising siRNA associated with plasma components, characterised in that the method includes a step in which the plasma components are dispersed in an aqueous medium.Type: ApplicationFiled: October 26, 2012Publication date: May 2, 2013Applicants: UNIVERSIDAD DE BARCELONA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), Universidad De Barcelona
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Publication number: 20130109083Abstract: A MIR-type device is described for determining the measurement and analysis of particles using optical means, especially particles of a suprananometric size, which can be found in a suspension injected in said device. Likewise, a particle analysis system is described that makes use of said device connected to a light source and to a reading source.Type: ApplicationFiled: January 11, 2011Publication date: May 2, 2013Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventor: Andreu Llobera Adán
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Publication number: 20130101565Abstract: The present invention falls within the field of biomedicine. Specifically, the present invention relates to the use of carbonic anhydrase II for the manufacture of a medicament for the prevention and/or treatment of the damage caused by ischemia, ischemia followed by reperfusion or toxins, acute failure or rejection of a transplanted organ, preferably the kidney. In a preferred embodiment, the toxin is cisplatin.Type: ApplicationFiled: July 12, 2010Publication date: April 25, 2013Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Georgina Hotter Corripio, José Luis Viñas, Anna Sola Martínez
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Publication number: 20130085212Abstract: The present invention relates to a procedure for the obtainment of a nanocomposite material through the technique of melt mixing comprising a polymeric matrix and a nanoreinforcement which has been previously dispersed in the same plastic or other matrix by means of electrospinning methods.Type: ApplicationFiled: November 2, 2012Publication date: April 4, 2013Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventor: Consejo Superior De Investigaciones Cientificas (CSIC)
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Publication number: 20130062286Abstract: The present invention relates to a method for obtaining materials based on treating solids by interaction with ferrofluids to give the final product a superparamagnetic behaviour at a moderate temperature. Said superparamagnetic materials are the result of the assembly of metal oxide nanoparticles associated to a compound with a surfactant effect, such as oleic acid, which are provided by a non-aqueous ferrofluid to different types of solids, preferably having adsorbent, absorbent or reactant and product support properties. The invention also relates to the material obtained by this procedure and its use in various applications such as adsorbents, sensors, ion exchangers the removal of toxic or radioactive contaminants, in chromatographic separation processes, in medical and biological applications, as carriers of biologically derived materials such as enzymes, as polymer fillers, absorption of electromagnetic radiation, as well as metal oxide and catalyst precursors.Type: ApplicationFiled: March 7, 2011Publication date: March 14, 2013Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Eduardo Ruiz Hitzky, María Pilar Aranda Gallego, Yorexis González Alfaro
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Publication number: 20130066057Abstract: The invention relates to a method for obtaining surfactants from cellulose and hemicellulose, which comprises one reaction in a single reactor (one pot) and which includes at least the following steps: a) a first hydrolysis step, in which the cellulose is mixed with at least one ionic liquid, water and a catalyst; and b) a second glycosylation step, in which at least one alcohol is added when the hydrolysis level of the cellulose is between 10 and 80%. The resulting products are preferably alkyl-?,?-glycosides.Type: ApplicationFiled: March 10, 2011Publication date: March 14, 2013Applicants: UNIVERSIDAD POLITECNICA DE VALENCIA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Avelino Corma Canos, Nicolás David Villandier
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Publication number: 20130052641Abstract: The present invention relates to a method for the detection and/or quantification of Streptococcus pneumoniae, a Gram-positive bacteria that is an important human pathogen, in an isolated biological sample, through magneto-amperometric biosensors, comprising detecting fragments of lytA gene of said microorganism, amplified through PCR, preferably asymmetric PCR or direct asymmetric PCR, by means of the hybridization thereof to a specific probe fully complementary to a region of said amplified fragment. Furthermore, the present invention also relates to the use of primers SEQ ID NO: 3 and 4 together with probes SEQ ID NO: 1 and/or SEQ ID NO: 2 to perform said detection. The biosensor developed to detect S. pneumoniae can be applied to different types of clinical samples from patients infected with this bacterium or other related bacteria. Preferably the clinical sample is an isolated biological fluid such as blood, cerebrospinal fluid, saliva or urine.Type: ApplicationFiled: December 16, 2010Publication date: February 28, 2013Applicants: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), CENTRO DE INVESTIGACION BIOMEDICA EN RED DE ENFERMEDADES RESPIRATORIAS (CIBERES), UNIVERSIDAD COMPLUTENSE DE MADRIDInventors: Ernesto Garcia Lopez, Pedro Garcia Gonzalez, José Luis Garcia Lopez, Susana Campuzano Ruiz, María Morales Areizaga, María Carmen Ardanuy Tisaire, José Manuel Pingarrón Carrazón, María Pedrero Muñoz
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Publication number: 20130047632Abstract: A system and a method for liquefaction of gases which are utilized in their liquid state as refrigerants in applications that require low temperatures, throughout various pressure ranges, from slightly above atmospheric pressures to pressures near the critical point. The system and method are based on closed-cycle cryocoolers and utilize the thermodynamic properties of the gas to achieve optimal liquefaction rates.Type: ApplicationFiled: October 30, 2012Publication date: February 28, 2013Applicants: Consejo Superior De Investigaciones Cientificas (CSIC), GWR Instruments, Inc., Universidad De ZaragozaInventors: Conrado Rillo Millán, Leticia Tocado Martínez, Richard C. Reineman, Richard J. Warburton
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Publication number: 20120309699Abstract: Compounds of general formula (I) for the treatment of inflammatory processes involved in numerous diseases such as intestinal inflammatory diseases. The invention moreover refers to compounds included within such general formula and to the procedure of the obtainment thereof.Type: ApplicationFiled: December 14, 2010Publication date: December 6, 2012Applicant: Consejo Superior de Investigaciones Cientificas (CSIC)Inventors: Juan Carlos Espin De Gea, Juan Carlos Morales Sánchez, Isabel Medina Mendez
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Publication number: 20120309108Abstract: The invention discloses a system for the simultaneous detection and/or quantification of various analytes in a sample or for the simultaneous detection and/or quantification of an analyte in various samples, comprising: a multi-electrode chip (10) comprising an array of microelectrodes (11a, 11b, 11c, 11d); a single-duct cell (20), comprising a groove (21) which accommodates the multi-electrode chip (10) and a duct (22) through which a fluid sample can sequentially flow through each of the microelectrodes (11a, 11b, 11c, 11d) of a multi-electrode chip (10) when the latter is inserted into the groove (21); and a multi-duct cell (30), comprising a groove (31) housing the multi-electrode chip (10) and several independent ducts (32a, 32b, 32c, 32d) through which several samples can pass independently through each electrode (11a, 11b, 11c, 11d) of the multi-electrode chip (10).Type: ApplicationFiled: December 14, 2010Publication date: December 6, 2012Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Javier Ramón Azcón, Francisco José Sánchez Baeza, María Pilar Marco Colas, Andrei Bratov Nikiforov, Natalia Abramova, Andrey Ipatov
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Publication number: 20120301514Abstract: The present invention relates to a bioactive composition obtained through the technique of electrospinning and composed of at least one polymer. Furthermore, the invention also discloses a process for the incorporation of such electrospun bioactive composition, as a coating over a plastic matrix to obtain composite materials for their use in both biodegradable and non-biodegradable biomedical implants and in tissue engineering.Type: ApplicationFiled: November 18, 2010Publication date: November 29, 2012Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: José M. Lagarón Cabello, Sergio Torres Giner, José V. Gimeno Alcañiz, María J. Ocio Zapata
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Publication number: 20120297502Abstract: Provided are DNA sequences encoding a novel type of AP2 domain-containing transcription factor as well as methods for obtaining similar sequences. Also described are methods for obtaining plants with improved growth and enhanced stress tolerance, particularly tolerance to osmotic and dehydration stress, such methods comprising expression of such DNA sequences in a plant or parts thereof. Further described are diagnostic compositions comprising the aforementioned DNA sequences and the use of such sequences in plant breeding and/or agriculture.Type: ApplicationFiled: June 20, 2012Publication date: November 22, 2012Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Montserrat Pages, Dimosthenis Kizis, Ana Isabel Sanz Molinero
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Publication number: 20120280184Abstract: The present invention relates to a composite material comprising a ceramic component, characterized in that it has a negative coefficient of thermal expansion, and carbon nanofilaments, to its obtainment process and to its uses as electrical conductor in microelectronics, precision optics, aeronautics and aerospace.Type: ApplicationFiled: December 14, 2010Publication date: November 8, 2012Applicant: Consejo Superior De Investigaciones Cientificas (CSIC)Inventors: Ramon Torrecillas San Millan, Olga Garcia Moreno, Maria Amparo Borrell Tomás, Adolfo Fernández Valdes
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Publication number: 20120269951Abstract: The present invention is based on the finding that stearin fats, obtainable by dry or solvent fractionation of sunflower high-stearic and high-oleic oils, optionally with seeding with tempered stearin crystals, have a high solid fat content at temperatures higher than 30° C., even higher than cocoa butter or other high saturated tropical fats with a similar disaturated triacylglycerol content due to the presence of disaturated triacylgiycerols rich in stearic acid, and improved melting point due to the presence of arachidic and behenic acids in these disaturated triacylgiycerols, being at the same time healthier that actual fats made from palm, palm kernel and coconut oils, or hydrogenated and trasesterified vegetable oils.Type: ApplicationFiled: October 21, 2010Publication date: October 25, 2012Applicant: Consejo Superior De Investigaciones Cientificas (CSIC)Inventors: Joaquín Jesús Salas Linan, Enrique Martinez Force, Miguel Angel Bootello García, Mónica Venegas Calerón, Rafael Garcés
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Publication number: 20120238437Abstract: The present invention provides a nanostructured composite material of ?-alumina-doped zirconia stabilised with cerium oxide and zirconia-doped ?-alumina, the process for obtaining it and the applications thereof, such as knee prostheses, hip prostheses, dental implants, mechanical components for pumps, alkaline batteries, ceramic components for stereotactic neurology, cutting tools, etc.Type: ApplicationFiled: July 23, 2010Publication date: September 20, 2012Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Ramóna Torrecillas San Millan, Luis Antonio Díaz Rodríguez
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Patent number: 8227666Abstract: Provided are DNA sequences encoding a novel type of AP2 domain-containing transcription factor as well as methods for obtaining similar sequences. Also described are methods for obtaining plants with improved growth and enhanced stress tolerance, particularly tolerance to osmotic and dehydration stress, such methods comprising expression of such DNA sequences in a plant or parts thereof. Further described are diagnostic compositions comprising the aforementioned DNA sequences and the use of such sequences in plant breeding and/or agriculture.Type: GrantFiled: July 11, 2008Date of Patent: July 24, 2012Assignee: Consejo Superior de Investigaciones Cientificas (CSIC)Inventors: Montserrat Pages, Dimosthenis Kizis, Ana Isabel Sanz Molinero
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Publication number: 20120165180Abstract: Starting from, as the initial composite, an LAS component in accordance with the composition LixAlySizOw, where x varies between 0.8 and 1.2, y varies between 0.8 and 1.2, z varies between 0.8 and 2, and w varies between 4 and 6, the LAS component is subsequently mixed with SiC nanoparticles, to obtain a stable, homogeneous suspension. Thereafter, the resulting suspension is dried. Subsequently, the material obtained is shaped and, finally, the material obtained in the preceding step is sintered.Type: ApplicationFiled: August 17, 2010Publication date: June 28, 2012Applicants: Fundacion Instituto Technologico De Materiales Asturias (ITMA), Consejo Superior De Investigaciones Cientificas (CSIC)Inventors: Ramon Torrecillas San Millan, Olga Garcia Moreno, Adolfo Fernandez Valdes
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Publication number: 20120157520Abstract: The present invention relates to compounds with a dioxane nucleus derived from carbohydrates and C-glucosides, process for obtaining same, to the use of such compounds as cytotoxic and antiproliferative agents and to the use thereof for producing a cancer treatment drug.Type: ApplicationFiled: June 25, 2010Publication date: June 21, 2012Applicants: Universidad De La Laguna, Consejo Superior De Investigaciones Cientificas (CSIC)Inventors: Alicia Boto Castro, Rosendo Hernández González, Dácil Hernádez Mesa, Eleuterio Álvarez González, Raquel Marín Cruzado, Mario Diaz González