Patents Assigned to Cordis Corporation
  • Patent number: 8142468
    Abstract: A guidewire navigable through body vessels of a human subject for delivery of a catheter or the like is provided. The guidewire includes an expandable segment movable between a collapsed state and an expanded state. If the catheter encounters resistance in a vessel and cannot be advanced further, the medical professional can move the expandable segment to the expanded state in which the expandable segment engages an inner surface of the catheter. The expandable segment locks onto the catheter, which allows the guidewire and catheter to be advanced through the vessel together as a single unit. An inflatable balloon catheter movable along the guidewire requires only a single tube and is sealed by the expandable segment of the guidewire for subsequent inflation.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: March 27, 2012
    Assignee: Cordis Corporation
    Inventors: Mark N. Inderbitzen, Robert Burgermeister, Kirk L. Johnson
  • Patent number: 8133346
    Abstract: Medical devices comprised of bonded joints are disclosed. The bonded joints comprise two surfaces bonded by a layer of phenoxy resin therebetween. In the preferred embodiments, bonded surfaces are comprised of materials that are suitable for medical devices. Most preferably, Nitinol comprises at least one bonded surface, however, other preferred materials may include, but are not limited to cobalt chromium, stainless steel, titanium, tantalum, and plastic. An intraluminal device comprised of a plurality of locations with a phenoxy resin layer is also disclosed wherein the phenoxy resin is further comprised of a radiopaque additive, a lubricious additive, or both radiopaque and lubricious additives. Also disclosed is an intraluminal device comprised of contiguous heterogeneous structural elements comprised of metallic members and non-metallic sections that are bonded together by a layer of phenoxy resin therebetween.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: March 13, 2012
    Assignee: Cordis Corporation
    Inventors: I Mark Huang, Michael V. Williamson
  • Patent number: 8133268
    Abstract: A plurality of endoluminal segments axially connected by fiber bridges is disclosed. The endoluminal segments may either be balloon-expandable or self-expanding, with the preferred embodiment being superelastic nitinol. The intraluminal segments may possess a textured surface or at least one geometric feature per segment, preferably located at the apex of a strut pair comprising the intraluminal segment, preferably capable of serving as an anchoring point for the fiber bridges. These geometric features may transmit axially compressive loads during deployment from a device such as a catheter, and may further be capable of interlocking the endoluminal segments when constrained within a device such as a catheter. The fibers comprising the bridges may be polymeric, silk, collagen, bioabsorbable, or a blend thereof. The fiber network comprising the bridges may be regularly oriented, randomly oriented, localized, or continuous.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: March 13, 2012
    Assignee: Cordis Corporation
    Inventor: Craig Bonsignore
  • Patent number: 8133253
    Abstract: A covered vascular filter can be placed in a blood vessel, for the purpose of intercepting thrombus. The filter may be introduced to a desired site for medical treatment through a catheter which defines a lumen or passage and a distal port or opening. The filter tends to resiliently expand from a compressed shape when it is inside the catheter lumen, to an expanded shape when the filter is pushed from the catheter lumen. A cover or sleeve over those portions of the filter that would otherwise contact the vessel wall tends to reduce pressure on the vessel wall. The sleeve also tends to resist growth of the vessel wall among the elements of the filter, called endothelialization. In other words, the sleeve resists incorporation of the filter elements into the vessel wall, enabling the filter to be retrievable for a longer time. The various features of the present invention may be used singly or in any combination, as desired in a particular vascular filter.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: March 13, 2012
    Assignee: Cordis Corporation
    Inventors: Gjalt Bosma, Yvonne L. Hoogeveen, Michiel Koorn, Rudolf T. Mulder
  • Patent number: 8118827
    Abstract: A guidewire having a spreader or at least one centering device which may be used to open occluded vessels or other biological passages, especially chronic total occlusions. The guidewire may be used to either open the lumen or to center a boring device within the lumen, so that the chronic total occlusion can be crossed, and an interventional procedure can then be performed.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: February 21, 2012
    Assignee: Cordis Corporation
    Inventors: Thomas W. Duerig, Hikmat Hojeibane, David C. Majercak
  • Patent number: 8109922
    Abstract: An orifice device for delivering one or more drugs includes an inner member having a proximal end and a distal end; and a plurality of windings helically wound around the inner member. Each winding defines a separate layer and each winding includes at least one wire helically wound around the inner member. The plurality of windings and the inner member define at least two separate channels for carrying one or more drugs therethrough. An inlet is at the proximal end of each of the plurality of windings and an outlet is at the distal end of the plurality of windings. At least one of the plurality of windings has a plurality of distinct wires helically wound in parallel around the inner member and at least one of the plurality of windings respectively.
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: February 7, 2012
    Assignee: Cordis Corporation
    Inventor: Scott M. Russell
  • Patent number: 8088156
    Abstract: A stent-graft fabricated from a thin-walled, high strength material provides for a more durable and lower profile endoprosthesis. The stent-graft comprises one or more stent segments covered with a fabric formed by the weaving, knitting or braiding of a biocompatible, high tensile strength, abrasion resistant, highly durable yarn such as ultra high molecular weight polyethylene. The one or more stent segments may be balloon expandable or self-expanding. The fabric may be attached to the stent segments utilizing any number of known materials and techniques. The fabric may be attached to the stent segments utilizing an attachment device that secures the fabric to a strut of the stent segment by sandwiching the fabric between itself and the stent strut.
    Type: Grant
    Filed: October 7, 2003
    Date of Patent: January 3, 2012
    Assignee: Cordis Corporation
    Inventors: Juan Borges, Clifford J. Dwyer, William L. Howat
  • Patent number: 8083792
    Abstract: An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arteries using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arteries to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: December 27, 2011
    Assignee: Cordis Corporation
    Inventors: Donald D. Boucher, Michael Dugery, Kirk L. Johnson, Isaac John Khan, David C. Majercak, Scott Lyle Rush
  • Patent number: 8080052
    Abstract: The present invention envisions an improved flexible connecting link used in conjunction with in-phase and half-phase circumferential sets of strut members. By increasing the total length and diagonality of the undulating connecting links, the present invention is a stent that provides increased flexibility during delivery and enhanced conformability to the shape of a curved artery when the stent is deployed into a curved vessel such as a tortuous coronary artery.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: December 20, 2011
    Assignee: Cordis Corporation
    Inventors: Robert Burgermeister, David C. Majercak, David R. Fischell, Hikmat Hojeibane, Robert E. Fischell
  • Publication number: 20110270307
    Abstract: Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved.
    Type: Application
    Filed: July 15, 2011
    Publication date: November 3, 2011
    Applicant: CORDIS CORPORATION
    Inventors: David Szabo, David Gale, Paul Johnson, Valerie Scott, Ben Morris, Greg Furnish, Trevor Beckett, Michael J. Trezza, II
  • Patent number: 8029561
    Abstract: The current invention comprises an approach to solving the clinical problem of restenosis, which involves the administration of combinations of drugs to patients undergoing PTCA or stent implantation. In one embodiment of the invention, an antiproliferative agent such as rapamycin, vincristine or taxol is administered in combination with the antiinflammatory agent, dexamethasone, to patients systemically, either subcutaneously or intravenously. In another embodiment of the invention, the antiproliferative and antiinflammatory agents are bound in a single formulation to the surface of a stent by means of incorporation within either a biodegradable or biostable polymeric coating. Alternatively, such drug combinations could be incorporated into a stent constructed with a grooved reservoir.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: October 4, 2011
    Assignees: Cordis Corporation, Wyeth
    Inventors: Gregory A. Kopia, Gerald H. Llanos, Robert Falotico
  • Patent number: 8003122
    Abstract: Medical devices may be utilized for local and regional therapeutic agent delivery. These therapeutic agents or compounds may reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including restenosis, vulnerable plaque, and atherosclerosis in type 2 diabetic patients. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Various materials and coating methodologies may be utilized to maintain the agents or compounds on the medical device until delivered and positioned.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: August 23, 2011
    Assignee: Cordis Corporation
    Inventor: Jonathon Z. Zhao
  • Patent number: 7989490
    Abstract: Liquid formulations, including solutions and suspensions of the various drugs, agents and/or compounds, may be locally or regionally delivered for the treatment of vascular disease. In each of these instances, antioxidants are utilized to prolong product integrity.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: August 2, 2011
    Assignee: Cordis Corporation
    Inventors: Robert Falotico, Jonathon Z. Zhao
  • Publication number: 20110177152
    Abstract: A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia following percutaneous transluminal coronary angiography. The local delivery of the drugs or agents provides for increased effectiveness and lower systemic toxicity.
    Type: Application
    Filed: April 5, 2011
    Publication date: July 21, 2011
    Applicant: CORDIS CORPORATION
    Inventors: Robert Falotico, Gregory A. Kopia, Gerard H. Llanos, John Siekierka Siekierka
  • Patent number: 7947302
    Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.
    Type: Grant
    Filed: December 15, 2008
    Date of Patent: May 24, 2011
    Assignee: Cordis Corporation
    Inventors: Robert Falotico, Jonathon Z. Zhao
  • Patent number: 7942920
    Abstract: A stent having a lattice and defining a substantially cylindrical configuration has a first open end and a second open end. The lattice has a collapsed configuration and an expanded configuration and a plurality of adjacent hoops. Each hoop has a plurality of adjacent loops and a plurality of bridges connect adjacent hoops. A plurality of extensions are provided on the lattice. And, each of the hoops, bridges and extensions define a cell.
    Type: Grant
    Filed: February 25, 2003
    Date of Patent: May 17, 2011
    Assignee: Cordis Corporation
    Inventor: David C. Majercak
  • Patent number: 7939095
    Abstract: Coatings are provided in which surfaces may be activated by covalently bonding a combination ofsilane derivatives (A) to the metal surface, covalently bonding a lactone polymer (B) to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a polyester (C) on the bonded lactone polymer. Biologically active agents or therapeutic compounds may be deposited with any of the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: May 10, 2011
    Assignee: Cordis Corporation
    Inventor: Jonathon Z. Zhao
  • Patent number: 7932265
    Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization.
    Type: Grant
    Filed: October 21, 2010
    Date of Patent: April 26, 2011
    Assignee: Cordis Corporation
    Inventors: Robert Falotico, Jonathon Z. Zhao
  • Patent number: 7927529
    Abstract: A bioabsorbable drug delivery device and various methods of making the same. The devices are preferably formed from bioabsorbable materials using low temperature fabrication processes, hereby drugs or other bio-active agents are incorporated into or onto the device and degradation of the drugs or other agents during processing is minimized. Radiopaque markers may also be incorporated into, or onto, the devices. The devices may be generally tubular helical stents comprised of a solid ladder or an open lattice configuration, or a hybrid combination thereof. The tubular helical stents are generally formed from precursor fibers, films or tubes. The solid ladder configuration provides increased radiopacity and increased radial strength, whereas the open lattice configuration provides better endothelialization and fluid flow through the stent.
    Type: Grant
    Filed: October 2, 2008
    Date of Patent: April 19, 2011
    Assignee: Cordis Corporation
    Inventor: Vipul Bhupendra Dave
  • Patent number: 7927309
    Abstract: The disclosure relates to an a catheter sheath introducer that is capable of being expanded from first diameter to second diameter in order to accommodate differently sized medical devices to be introduced by the sheath introducer. The device is structured such that it does not foreshorten when expanded.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: April 19, 2011
    Assignee: Cordis Corporation
    Inventor: Mark Erwin Palm