Patents Assigned to Cordis Corporation
  • Patent number: 7575591
    Abstract: A prosthesis configured for establishing a fluid flow path through an artery or the like includes a generally cylindrical body portion formed from graft material. In accordance with a preferred aspect of the device, at least a portion of the graft material is profiled where the profile defines a geometric pattern, e.g. a series of Z pleats.
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: August 18, 2009
    Assignee: Cordis Corporation
    Inventors: William L. Howat, Tara Schaneville
  • Publication number: 20090204204
    Abstract: A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia following percutaneous transluminal coronary angiography. The local delivery of the drugs or agents provides for increased effectiveness and lower systemic toxicity.
    Type: Application
    Filed: April 9, 2009
    Publication date: August 13, 2009
    Applicant: CORDIS CORPORATION
    Inventors: Robert Falotico, Gregory A. Kopia, Gerard H. Llanos, John Siekierka
  • Patent number: 7572270
    Abstract: A balloon catheter and stent delivery system for medical treatment of a patient includes a balloon having a pattern of ridges in an initial deflated state. The ridges may cooperate with structural elements of a stent crimped onto the balloon, to increase and enhance longitudinal retention of the stent while the catheter system is advanced or withdrawn. Upon inflation, the balloon recovers to an inflated shape having a cylindrical working portion. The balloon catheter thus provides for uniform expansion of the stent when the balloon is inflated. The present invention also tends to protect the leading or distal end of the stent during advancement, and tends to protect the proximal end of the stent during any withdrawal of the catheter system.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: August 11, 2009
    Assignee: Cordis Corporation
    Inventor: Eric Gerard Johnson
  • Patent number: 7556642
    Abstract: A balloon dilatation catheter has a relatively strong proximal tube made of a material such as for example metal hypotubing. The distal end of the catheter includes an inflatable medical device or balloon, an inflation lumen and a guidewire lumen. A transition assembly or stiffening member is positioned between the proximal tube and the distal end section, providing for a flexible transition between the two components of diverse stiffness, namely the proximal tube and the flexible distal end portion. A proximal end of the stiffening member may float within a distal end of the proximal tube but the stiffening member distal end is affixed near its distal end to the shaft. The dilatation catheter may have a rapid exchange configuration, and is generally used in conjunction with a guiding catheter. During a procedure when the catheters are within the vascular system, the portion of the dilatation catheter near the transition readily follows curved portions of the inserted guiding catheter.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: July 7, 2009
    Assignee: Cordis Corporation
    Inventor: Thomas N. Trotta
  • Patent number: 7527632
    Abstract: Medical devices, and in particular implantable medical devices, including self-expanding stents, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: May 5, 2009
    Assignee: Cordis Corporation
    Inventors: Michael J. Houghton, David C. Majercak
  • Patent number: 7520863
    Abstract: A bi-directional steerable guidewire having a deflectable distal tip which comprises a longitudinal hypotube and an interlocking spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining member which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: April 21, 2009
    Assignee: Cordis Corporation
    Inventors: David Grewe, David C. Majercak
  • Patent number: 7500988
    Abstract: A stent-graft for insertion into a body lumen, such as a blood vessel, is utilized in order to repair such lumen. The stent-graft includes a substantially cylindrical hollow expandable stent comprising a plurality of interconnected struts. The stent has a distal end and a proximal end, and an interior surface and an exterior surface. At least one strut of the stent has first and second apertures extending therethrough from the interior surface to the exterior surface. The stent-graft also includes a graft member covering a predetermined portion of least one of the interior surface and the exterior surface of the stent. In addition, the stent-graft further includes a staple for attaching the graft member to the stent. The staple has a crown and two legs extending therefrom. At least one of the legs of the staple extends through the graft material and through the first aperture. Both of the legs are bent inwardly towards said crown such that they evert back and extend through the second aperture.
    Type: Grant
    Filed: November 16, 2000
    Date of Patent: March 10, 2009
    Assignee: Cordis Corporation
    Inventors: Frank Butaric, Bill K. Ng, Marc Ramer, Dieter Stoeckel, Gregory Mast, Luis A. Davila, Kenneth S. Solovay
  • Publication number: 20090043332
    Abstract: A medical filter has a double-basket design, in which the two filter baskets have balanced filtering efficiencies, so that both filter baskets tend to collect or capture amounts of material that are approximately equivalent. In other words, a second or “downstream” filter basket may be designed to have a filter efficiency greater than that of a first or “upstream” filter basket. There are a variety of ways in which this tailored filter basket performance can be achieved. Some examples include increasing the number of struts or decreasing the size of the filter cells or other filter elements of the second or “downstream” filter basket. Likewise, a similar result may be reached by decreasing the number of struts or increasing the size of the filter cells or other filter elements of the first or “upstream” filter basket. In some cases, such a filter may be used in a blood vessel, for the purpose of intercepting thrombus.
    Type: Application
    Filed: April 16, 2005
    Publication date: February 12, 2009
    Applicant: CORDIS CORPORATION
    Inventors: Jason R. Sullivan, Wai Chung Jonathan Wong
  • Patent number: 7485141
    Abstract: The present invention relates to a medical device, and more particularly to a method of forming a tubular membrane on a radially expandable structural frame. In one aspect, a structural frame is placed over a spinning mandrel and a fiber is electro-statically spun over at least a portion of the structural frame forming a membrane. A transfer sheath may be used between the mandrel and structural frame to prevent the electrostatically spun fiber from adhering to the mandrel. In another aspect, a first membrane is spun over the mandrel before the structural frame is placed over the mandrel. In this aspect, at least a portion of the structural frame is sandwiched between the membranes. The membrane or membranes and structural frame form a fiber spun frame assembly. The fiber spun frame assembly may be coated with an elastic polymer. In addition, the membrane or membranes may go through some post processing to achieve desired characteristics or configurations.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: February 3, 2009
    Assignee: Cordis Corporation
    Inventors: David Christopher Majercak, Vipul Bhupendra Dave, Iksoo Chun, Mark B. Roller
  • Patent number: 7481778
    Abstract: A steerable guidewire having a deflectable distal tip which comprises a longitudinal hypotube and an interlocking spring coil attached to the distal end of the hypotube and also includes a longitudinally movable deflection member which is attached to the distal end of the spring coil and a tip retaining ribbon which extends from the distal end of the hypotube to the distal end of the spring coil for providing very precise deflection of the distal tip. The distal end of the deflection member has “skived,” or tapered, sides to enhance the flexibility of the guidewire.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: January 27, 2009
    Assignee: Cordis Corporation
    Inventors: Rudolph Cedro, David D. Grewe, Hikmat Hojeibane
  • Patent number: 7476244
    Abstract: A system for delivering at least one medical device to a desired location for treatment, and then selectively deploy it in position, includes an improved handle having a first and second independently movable actuator for moving an outer sheath. A locking mechanism may be provided that resists inadvertent or accidental movement or retraction of the stent delivery system components during packaging, sterilization, shipping, storage, handling and preparation of the stent delivery system.
    Type: Grant
    Filed: January 8, 2004
    Date of Patent: January 13, 2009
    Assignee: Cordis Corporation
    Inventors: Jon Buzzard, Frederick Feller, III
  • Patent number: 7478008
    Abstract: A method and system for the non-destructive analysis of medical devices uses a confocal Raman microscope and other non-destructive analytical tools to assess the spatial distribution of components of an object such as the distribution of an active pharmaceutical ingredient (API) within a polymer matrix. In a preferred embodiment, confocal Raman spectroscopy was used to differentiate each component found in the sirolimus-eluting coronary stent. The unique spectral features identified for each component were then used to develop three separate calibration curves to describe the solid phase distribution found on drug-polymer coated stents. The calibration curves were obtained by analyzing confocal Raman spectral depth profiles from a set of 16 unique formulations of drug-polymer coatings sprayed onto stents and planar substrates.
    Type: Grant
    Filed: July 19, 2007
    Date of Patent: January 13, 2009
    Assignee: Cordis Corporation
    Inventors: Karin Maria Balss, Gerard Llanos, Cynthia Anne Maryanoff, George Papandreou, Vladimir Veselov
  • Publication number: 20080317827
    Abstract: Methods of preparing devices for delivering at least one therapeutic agent to a target vessel in a mammal, the devices prepared by such methods, and uses of such devices for delivering a therapeutic agent, such as an antiproliferative agent, to a target vessel.
    Type: Application
    Filed: September 5, 2008
    Publication date: December 25, 2008
    Applicant: CORDIS CORPORATION
    Inventors: Carol Wright, Gerard H. Llanos, Ronald Rakos, Kristen King
  • Publication number: 20080300544
    Abstract: The disclosure relates to an a catheter sheath introducer that is capable of being expanded from first diameter to second diameter in order to accommodate differently sized medical devices to be introduced by the sheath introducer. The device is structured such that it does not foreshorten when expanded.
    Type: Application
    Filed: May 29, 2007
    Publication date: December 4, 2008
    Applicant: Cordis Corporation
    Inventor: Mark Erwin Palm
  • Patent number: 7455652
    Abstract: Fluid delivery devices having a porous applicator, as well as methods for using the same in the treatment of aortic valve stenosis, are provided. The subject devices further include a ventricular occlusion balloon and a compliant element that is configured to envelope the occlusion balloon. Also provided are systems and kits that include the subject fluid delivery devices.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: November 25, 2008
    Assignee: Cordis Corporation
    Inventor: Rob Laird
  • Patent number: 7419678
    Abstract: A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia following percutaneous transluminal coronary angiography. The local delivery of the drugs or agents provides for increased effectiveness and lower systemic toxicity.
    Type: Grant
    Filed: May 7, 2003
    Date of Patent: September 2, 2008
    Assignees: Cordis Corporation, Wyeth
    Inventor: Robert Falotico
  • Patent number: 7407647
    Abstract: The present invention discloses an organic radiographic contrasting agent containing an aliphatic or alicyclic backbone and multiple halogen-substituted aromatic groups. Each of the halogen-substituted aromatic groups in the radiographic contrasting agent is substituted with at least three halogen atoms and is covalently attached to the aliphatic or alicyclic backbone. The present invention also discloses a radio-opaque polymeric material comprising the radiographic contrasting agent and at least one polymer. The radiographic contrasting agent is physically admixed with the at least one polymer or physically embedded or dispersed in the at least one polymer. The radio-opaque polymeric material provides enhanced contrasting intensity in radiographic imaging. The radio-opaque polymeric material can be applied on at least a portion of one surface of a medical device. The radio-opaque polymeric material can also be used to construct a medical device, a component thereof, or a portion of a component thereof.
    Type: Grant
    Filed: December 7, 2005
    Date of Patent: August 5, 2008
    Assignee: Cordis Corporation
    Inventor: Jonathon Z. Zhao
  • Patent number: 7399308
    Abstract: A removable vascular filter system for capture and retrieval of emboli while allowing continuous perfusion of blood, comprising a porous filter membrane and a filter membrane support structure. This system is useful for any percutaneous angioplasty, stenting, thrombolysis or tissue ablation procedure. The system may minimize the incidence of stroke, myocardial infarction or other clinical complications that may be associated with these procedures.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: July 15, 2008
    Assignee: Cordis Corporation
    Inventors: Thomas Borillo, Mark Maciejewski, Gregg S. Sutton, Jeffrey Welch
  • Patent number: 7399314
    Abstract: A stent graft having graft material attached to a stent structure while providing a low profile to the stent graft in its crimped state. The graft material may be attached to an internal surface, an external surface, or both the internal surface and the external surface of the stent. The graft material may cover all or part of such surfaces. The stent graft is expandable upon delivery to the intended treatment site. The expandable nature of the stent graft may be accomplished by self-expanding materials, or through other methods, such as balloon expansion, as generally practiced in the art. The stent graft material is comprised of durable biocompatible materials as generally practiced in the art. The stent graft in its crimped state comprises a low profile fluid flow conduit that is preferably percutaneously delivered, but that may be surgically emplaced to the intended treatment site.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: July 15, 2008
    Assignee: Cordis Corporation
    Inventors: Frank Butaric, I. John Khan, Diana M. Sanchez
  • Patent number: 7393952
    Abstract: An improved process for coating implantable medical devices utilizes a number of techniques for improving the stability of therapeutic agents contained within the coating. The stability of the therapeutic agents may be improved by creating substantially solvent-free, amorphous forms of the therapeutic agents.
    Type: Grant
    Filed: August 24, 2005
    Date of Patent: July 1, 2008
    Assignee: Cordis Corporation
    Inventors: Cynthia A. Maryanoff, Karel Six, Roger Vandecruys