Patents Assigned to Cosmo Technologies Ltd.
-
Publication number: 20230135346Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.Type: ApplicationFiled: December 27, 2022Publication date: May 4, 2023Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi MORO, Luigi Maria LONGO
-
Publication number: 20230130628Abstract: Herein described are solid oral compositions of dyes for use in diagnostic endoscopy, preferably colon endoscopy.Type: ApplicationFiled: December 20, 2022Publication date: April 27, 2023Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi MORO, Alessandro REPICI
-
Publication number: 20230128438Abstract: The present invention relates to certain cortexolone derivatives of formula (I) and the use of the same as antitumor active ingredients for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis. The present invention also relates to pharmaceutical compositions comprising cortexolone derivatives of formula (I) as active ingredients and at least one physiologically acceptable excipient, and to the use of the pharmaceutical compositions as antitumor medicinal products.Type: ApplicationFiled: December 19, 2022Publication date: April 27, 2023Applicant: COSMO TECHNOLOGIES LTD.Inventor: Mara GERLONI
-
Patent number: 11564883Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.Type: GrantFiled: November 7, 2018Date of Patent: January 31, 2023Assignee: COSMO TECHNOLOGIES LTD.Inventors: Luigi Moro, Luigi Maria Longo
-
Publication number: 20210299145Abstract: The present invention relates to certain cortexolone derivatives of formula (I) and the use of the same as antitumor active ingredients for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis. The present invention also relates to pharmaceutical compositions comprising cortexolone derivatives of formula (I) as active ingredients and at least one physiologically acceptable excipient, and to the use of the pharmaceutical compositions as antitumor medicinal products.Type: ApplicationFiled: April 6, 2021Publication date: September 30, 2021Applicant: COSMO TECHNOLOGIES LTD.Inventor: Mara GERLONI
-
Patent number: 11123460Abstract: The invention provides a pharmaceutical composition in form of emulsion or microemulsion for use in an endoscopic procedure, preferably said endoscopic procedure comprising the administration of said pharmaceutical composition to a human with the aim of improving and facilitating the resection of the lesion by raising the area where the lesion is located. The invention herein disclosed provides a method for performing an endoscopic procedure, said method preferably comprising the administration of a pharmaceutical composition in form of emulsion or microemulsion to a human.Type: GrantFiled: October 25, 2019Date of Patent: September 21, 2021Assignee: COSMO TECHNOLOGIES LTD.Inventors: Luigi Maria Longo, Luigi Moro, Enrico Frimonti, Alessandro Repici
-
Publication number: 20210154300Abstract: The invention provides a composition for use as a delivery vehicle comprising at least one thermo-responsive polymer (polymer A) and at least one ion-sensitive polymer (polymer B) in a liquid formulation. Polymer A is preferably a polyoxyethylene-polyoxypropylene block copolymer or a cellulose derivative. Polymer B a polysaccharide. The composition can include an active substance for delivery or can be used as a delivery vehicle for a substance added at the time of administration such as mesenchymal stem cells.Type: ApplicationFiled: December 20, 2018Publication date: May 27, 2021Applicant: COSMO TECHNOLOGIES LTD.Inventors: Franca FERRARI, Cristina BONFERONI, Giuseppina SANDRI, Luigi Maria LONGO, Cristina MACELLONI, Silvia ROSSI
-
Publication number: 20210093576Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.Type: ApplicationFiled: December 7, 2020Publication date: April 1, 2021Applicant: COSMO TECHNOLOGIES LTD.Inventors: Mauro AJANI, Roberta BOZZELLA, Giuseppe CELASCO, Roberto VILLA
-
Publication number: 20210007993Abstract: The present invention provides an innovative combination of biomaterials, multifunctional polymers, able to structure themselves at the site of action. The innovative combination of biomaterials of the invention is formulated in a solid composition and can be used as a versatile delivery vehicle or carrier in many pharmaceutical fields. The solid composition comprising the combination of biomaterials of the invention is provided to target delivery for medical purposes in humans.Type: ApplicationFiled: December 20, 2018Publication date: January 14, 2021Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi Maria LONGO, Cristina MACELLONI, Silvia ROSSI, Franca FERRARI
-
Publication number: 20200281850Abstract: Oral pharmaceutical compositions containing rifamycin SV, or a pharmaceutically salt thereof, characterized in that they are formulated in a higher strength (about 600 mg/tablet) and in such a manner to obtain a modified profile of the rifamycin SV, or a pharmaceutically acceptable salt thereof, in the proximal portion of the intestine, i.e. in the small intestine (duodenum, jejunum and ileum). In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of small intestine bacterial overgrowth (SIBO) and/or irritable bowel syndrome (IBS) and/or in the treatment of cholera. In one embodiment, the disclosed oral pharmaceutical compositions are used in the prevention and/or treatment in a subject of hepatic encephalopathy, hepatic cirrhosis, pouchitis and/or spontaneous bacterial perotinitis.Type: ApplicationFiled: November 7, 2018Publication date: September 10, 2020Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi MORO, Luigi Maria LONGO
-
Publication number: 20200268909Abstract: The present application discloses solid compositions for the oral administration of dyes, and diagnostic use thereof. Preferably, such diagnostic use is aimed at the diagnostic evaluation of the gastrointestinal tract.Type: ApplicationFiled: September 27, 2019Publication date: August 27, 2020Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi MORO, Mauro Severino AJANI, Roberto VILA, Giuseppe CELASCO, Alessandro REPICI
-
Publication number: 20200215080Abstract: The present invention relates to certain cortexolone derivatives of formula (I) and the use of the same as antitumor active ingredients for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis. The present invention also relates to pharmaceutical compositions comprising cortexolone derivatives of formula (I) as active ingredients and at least one physiologically acceptable excipient, and to the use of the pharmaceutical compositions as antitumor medicinal products.Type: ApplicationFiled: March 16, 2020Publication date: July 9, 2020Applicant: COSMO TECHNOLOGIES LTD.Inventor: Mara GERLONI
-
Publication number: 20200129643Abstract: Herein described are solid oral compositions of dyes for use in diagnostic endoscopy, preferably colon endoscopy.Type: ApplicationFiled: June 12, 2019Publication date: April 30, 2020Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi Moro, Alessandro Repici
-
Publication number: 20200061212Abstract: The present invention relates to methods for improving the detection of pathologies in the colon and method of flagging the mucosal lesions in the colon.Type: ApplicationFiled: November 28, 2017Publication date: February 27, 2020Applicant: COSMO TECHNOLOGIES LTD.Inventor: Luigi MORO
-
Publication number: 20200054797Abstract: The invention provides a pharmaceutical composition in form of emulsion or microemulsion for use in an endoscopic procedure, preferably said endoscopic procedure comprising the administration of said pharmaceutical composition to a human with the aim of improving and facilitating the resection of the lesion by raising the area where the lesion is located. The invention herein disclosed provides a method for performing an endoscopic procedure, said method preferably comprising the administration of a pharmaceutical composition in form of emulsion or microemulsion to a human.Type: ApplicationFiled: October 25, 2019Publication date: February 20, 2020Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi Maria LONGO, Luigi MORO, Enrico FRIMONTI, Alessandro REPICI
-
Publication number: 20200000926Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.Type: ApplicationFiled: August 9, 2019Publication date: January 2, 2020Applicant: COSMO TECHNOLOGIES LTD.Inventors: Luigi MORO, Luigi Maria LONGO, Enrico FRIMONTI, Alessandro REPICI
-
Publication number: 20190192441Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.Type: ApplicationFiled: March 1, 2019Publication date: June 27, 2019Applicant: COSMO TECHNOLOGIES LTD.Inventors: Mauro AJANI, Roberta BOZZELLA, Giuseppe CELASCO, Roberto VILLA
-
Publication number: 20190175618Abstract: The present invention provides certain cortexolone derivatives, and the same for use as antitumor active ingredients for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis. The present invention also provides pharmaceutical compositions comprising the cortexolone derivatives as active ingredients and at least one physiologically acceptable excipient, and to the use of said pharmaceutical compositions as antitumor medicinal products.Type: ApplicationFiled: February 12, 2019Publication date: June 13, 2019Applicant: COSMO TECHNOLOGIES LTD.Inventor: Mara GERLONI
-
Patent number: 10265420Abstract: The present application discloses solid compositions for the oral administration of dyes, and diagnostic use thereof. Preferably, such diagnostic use is aimed at the diagnostic evaluation of the gastrointestinal tract.Type: GrantFiled: March 4, 2016Date of Patent: April 23, 2019Assignee: COSMO TECHNOLOGIES LTD.Inventors: Luigi Moro, Mauro Severino Ajani, Roberto Villa, Giuseppe Celasco, Alessandro Repici
-
Publication number: 20190091240Abstract: The present invention relates to certain cortexolone derivatives of formula (I) and the use of the same as antitumor active ingredients for the curative or adjuvant, or neoadjuvant or palliative treatment of precancerous lesions, dysplasias, metaplasias and tumor diseases, including malignant neoplasias and metastasis. The present invention also relates to pharmaceutical compositions comprising cortexolone derivatives of formula (I) as active ingredients and at least one physiologically acceptable excipient, and to the use of the pharmaceutical compositions as antitumor medicinal products.Type: ApplicationFiled: November 23, 2018Publication date: March 28, 2019Applicant: COSMO TECHNOLOGIES LTD.Inventor: Mara GERLONI