Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
Type:
Grant
Filed:
November 24, 2015
Date of Patent:
June 14, 2016
Assignee:
COSMO TECHNOLOGIES LTD.
Inventors:
Luigi Moro, Luigi Maria Longo, Enrico Frimonti, Alessandro Repici
Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
Type:
Application
Filed:
November 24, 2015
Publication date:
March 17, 2016
Applicant:
COSMO TECHNOLOGIES LTD.
Inventors:
Luigi MORO, Luigi Maria LONGO, Enrico FRIMONTI, Alessandro REPICI
Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
Type:
Grant
Filed:
November 18, 2014
Date of Patent:
January 5, 2016
Assignee:
COSMO TECHNOLOGIES LTD.
Inventors:
Luigi Moro, Luigi Maria Longo, Enrico Frimonti, Alessandro Repici
Abstract: The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
Type:
Application
Filed:
November 18, 2014
Publication date:
May 21, 2015
Applicant:
COSMO TECHNOLOGIES LTD.
Inventors:
Luigi MORO, Luigi Maria LONGO, Enrico FRIMONTI, Alessandro REPICI
Abstract: Pharmaceutical or dietary composition containing, as active ingredients, at least one short-chain fatty acid or salt, ester and/or amide thereof, in combination with a complex sugar and/or dietary fibre. The complex sugar and/or dietary fibre is selected from inulin, pectin, dextrin, maltodextrin or derivatives thereof and with one or more pharmacologically acceptable excipients. The composition has (a) a matrix consisting of lipophilic compounds with a melting point lower than 90° C. and optionally amphiphilic compounds in which the active ingredient are at least partially incorporated, (b) an amphiphilic matrix; and (c) an outer hydrophilic matrix in which the lipophilic matrix and the amphiphilic matrix are dispersed.
Type:
Application
Filed:
September 25, 2014
Publication date:
January 8, 2015
Applicant:
COSMO TECHNOLOGIES LTD.
Inventors:
Mauro AJANI, Roberto VILLA, Giuseppe CELASCO, Luigi MORO
Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
Type:
Grant
Filed:
August 22, 2012
Date of Patent:
June 3, 2014
Assignee:
Cosmo Technologies Ltd.
Inventors:
Mauro Ajani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
Abstract: The present application discloses solid compositions for the oral administration of dyes, and diagnostic use thereof. Preferably, such diagnostic use is aimed at the diagnostic evaluation of the gastrointestinal tract.
Type:
Grant
Filed:
September 4, 2012
Date of Patent:
October 1, 2013
Assignee:
Cosmo Technologies Ltd.
Inventors:
Luigi Moro, Mauro Severino Ajani, Roberto Villa, Giuseppe Celasco, Alessandro Repici
Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
Type:
Grant
Filed:
September 14, 2012
Date of Patent:
September 10, 2013
Assignee:
Cosmo Technologies Ltd.
Inventors:
Mauro Ajani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
Abstract: The invention relates to the use of mexiprostil in the treatment and/or prevention of inflammatory bowel disease and of irritable bowel syndrome, to the combinations of mexiprostil with other drugs, and also to a novel method for the synthesis of mexiprostil.
Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
Type:
Grant
Filed:
May 3, 2005
Date of Patent:
July 16, 2013
Assignee:
Cosmo Technologies Ltd.
Inventors:
Mauro Ajani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
Abstract: Pharmaceutical and/or dietary compositions based on short chain fatty acids or salts, esters and/or amides thereof in combination with one or more dietary soluble or water-dispersible fibre and at least one flavouring agent are disclosed.
Abstract: The present application discloses solid compositions for the oral administration of dyes, and diagnostic use thereof. Preferably, such diagnostic use is aimed at the diagnostic evaluation of the gastrointestinal tract.
Type:
Application
Filed:
September 4, 2012
Publication date:
March 7, 2013
Applicant:
COSMO TECHNOLOGIES LTD.
Inventors:
Luigi MORO, Mauro Severino AJANI, Roberto VILLA, Giuseppe CELASCO, Alessandro REPICI
Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
Type:
Grant
Filed:
April 19, 2012
Date of Patent:
September 11, 2012
Assignee:
Cosmo Technologies Ltd.
Inventors:
Mauro Ajani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
Abstract: Pharmaceutical compositions with differentiated, controlled and/or site-specific release are claimed for the oral or rectal administration of peptide or protein substances, including antibodies and soluble receptors capable of antagonising the pathogenetic role of several cell mediators such as interleukines, chemokines, growth factors, tissue necrosis factors, and interferons. Through the incorporation of the peptide or protein substance inside a controlled and/or site-specific release preparation, the application of this invention permits transporting the substances directly into the intestinal environment where a reduced quantity of proteolytic enzymes is present, a less aggressive microenvironment for the integrity of the protein structure and sequence.
Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
Type:
Application
Filed:
June 5, 2008
Publication date:
September 25, 2008
Applicant:
COSMO TECHNOLOGIES LTD.
Inventors:
Mauro Aiani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
Abstract: The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
Type:
Application
Filed:
May 3, 2005
Publication date:
October 25, 2007
Applicant:
COSMO TECHNOLOGIES LTD.
Inventors:
Mauro Aiani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa