Patents Assigned to CVDevices, LLC
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Patent number: 11771558Abstract: Methods and devices for controlling blood perfusion pressure along with regional mild hypothermia. In at least one embodiment of a device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, a partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel and to equalize the first blood pressure at the first area with the second blood pressure at the second area, and a regional hypothermia system operably coupled thereto, the regional hypothermia system operable to reduce and/or regulate a temperature of a bodily fluid flowing therethrough.Type: GrantFiled: July 7, 2020Date of Patent: October 3, 2023Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 11712331Abstract: Endoprosthesis assemblies and methods for using the same. In at least one embodiment, the endoprosthesis assembly comprises an endoprosthesis comprising an impermeable inner wall defining an endoprosthesis lumen sized and shaped to permit fluid to flow therethrough, a distal balloon positioned at or near a distal end of the endoprosthesis and capable of inflation to anchor the distal end of the endoprosthesis within a luminal organ, and a proximal balloon positioned at or near a proximal end of the endoprosthesis and capable of inflation to anchor the proximal end of the endoprosthesis within the luminal organ, wherein when the endoprosthesis assembly is positioned within the luminal organ at or near an aneurysm sac, inflation of the distal balloon and the proximal balloon effectively isolates the aneurysm sac and prevents fluid within the aneurysm sac from flowing past the distal balloon and the proximal balloon.Type: GrantFiled: April 16, 2019Date of Patent: August 1, 2023Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Publication number: 20230037891Abstract: Thrombectomy systems and devices and methods of using the same. In an exemplary embodiment of a thrombectomy system of the present disclosure, the thrombectomy system comprises a thrombectomy sheath, comprising a circumferential outer wall reinforced with a reinforcement, configured as an elongated tube having a lumen therethrough; and a sonovisible element positioned at or near a distal end of the circumferential outer wall; wherein the thrombectomy sheath is sized and shaped to be at least partially positioned within a vein proximal to a thrombus or other item within the vein and further configured to expand to contact the vein to secure the thrombectomy sheath within the vein; and wherein the lumen is sized and shaped to receive a device selected from the group consisting of a balloon catheter and a snare having a loop.Type: ApplicationFiled: October 18, 2022Publication date: February 9, 2023Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Seshadri Raju
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Publication number: 20220354538Abstract: Devices, systems, and methods for use with suction within a mammalian body. In an exemplary embodiment of a device of the present disclosure, the device comprises one or more of the following: an inner tube, an outer tube, and a foldable portion, whereby movement of the two tubes relative to one another causes the foldable portion to form a suction cup, and conversely causes a suction cup to form a foldable portion, depending on the direction of relative movement.Type: ApplicationFiled: July 26, 2022Publication date: November 10, 2022Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Zachary Berwick
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Patent number: 11471182Abstract: Thrombectomy systems and devices and methods of using the same. In an exemplary embodiment of a thrombectomy system of the present disclosure, the thrombectomy system comprises a thrombectomy sheath, comprising a circumferential outer wall reinforced with a reinforcement, configured as an elongated tube having a lumen therethrough; and a sonovisible element positioned at or near a distal end of the circumferential outer wall; wherein the thrombectomy sheath is sized and shaped to be at least partially positioned within a vein proximal to a thrombus or other item within the vein and further configured to expand to contact the vein to secure the thrombectomy sheath within the vein; and wherein the lumen is sized and shaped to receive a device selected from the group consisting of a balloon catheter and a snare having a loop.Type: GrantFiled: October 8, 2019Date of Patent: October 18, 2022Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Seshadri Raju
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Patent number: 11395677Abstract: Devices, systems, and methods for use with suction within a mammalian body. In an exemplary embodiment of a device of the present disclosure, the device comprises one or more of the following: an inner tube, an outer tube, and a foldable portion, whereby movement of the two tubes relative to one another causes the foldable portion to form a suction cup, and conversely causes a suction cup to form a foldable portion, depending on the direction of relative movement.Type: GrantFiled: February 9, 2017Date of Patent: July 26, 2022Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Zachary Berwick
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Patent number: 11351345Abstract: Systems and methods for selective auto-retroperfusion along with regional mild hypothermia.Type: GrantFiled: October 22, 2019Date of Patent: June 7, 2022Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Publication number: 20220088377Abstract: Devices, systems, and methods for accessing the internal and external tissues of the heart are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for localized delivery of substances to the heart tissue. In addition, various disclosed embodiments provide access to the internal surface of the heart for aspiration and delivery of substances to a targeted region without disturbing or interfering with nearby structures or surfaces.Type: ApplicationFiled: December 7, 2021Publication date: March 24, 2022Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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Patent number: 11253260Abstract: A device and system are described that are capable of isolating at least one targeted tissue and forming an anastomosis between two internal body structures though a completely endoscopic procedure. Further, the device and system described generally comprise two tubular members that are capable of moving in a telescopic fashion relative to one another. Additionally, a method is described for using the device and/or system to bypass the duodenum from digestion.Type: GrantFiled: March 26, 2019Date of Patent: February 22, 2022Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Publication number: 20210401565Abstract: A quick-connector for use with an autoretroperfusion and hypothermia system and methods of using the connector. The connector comprises a coolant inlet, a coolant outlet, a coolant reservoir, a blood lumen outlet, a blood lumen inlet, and a blood lumen, whereby the coolant outlet is configured to accept a cooling product from the reservoir, the reservoir is configured to accept cooling product from the coolant inlet. Flowing blood powered by the patient's heart may enter the connector through the blood lumen inlet, travel through the blood lumen while being cooled by cooling product in the reservoir, and leave the connector through the blood lumen outlet. The temperature of blood leaving the connector can be measured at the blood lumen outlet. Catheters can be attached to the blood lumen inlet and blood lumen outlet to receive and send blood, respectively. A cooling system can be attached to the coolant inlet and coolant outlet to provide a source of cooling product.Type: ApplicationFiled: June 29, 2021Publication date: December 30, 2021Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR., Zachary Berwick
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Publication number: 20210401318Abstract: Methods of determining an index of vessel and heart function are disclosed. The methods determine the maximum volume and rate of change of volume so that an efficiency of the heart can be determined. Conductance readings indicative of the heart can be taken from a variety of locations such as the lumen of a vessel, the lumen of a heart, the pericardial space, and the epicardial surface. Said conductance readings are then used to determine the efficiency of the heart.Type: ApplicationFiled: September 7, 2021Publication date: December 30, 2021Applicant: CVDevices, LLCInventor: Ghassan S. Kassab
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Publication number: 20210393426Abstract: Devices and systems to fit around a tissue or organ and methods of using the same. In at least one embodiment of an implantable device of the present disclosure, the implantable device comprises a first engaging component comprising a first rigid inner plate at least partially surrounded by a first flexible coating, a second engaging component comprising a second rigid inner plate at least partially surrounded by a coating selected from the group consisting of the first flexible coating and the second flexible coating, a first c-ring and a second c-ring coupled to the engaging components, and a cover flap coupled to either the first engaging component or the second engaging component and capable of either further coupling to the second engaging component when initially coupled to the first engaging component or further coupling to the first engaging component when initially coupled to the second engaging component.Type: ApplicationFiled: August 31, 2021Publication date: December 23, 2021Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Thomas A. Kramer
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Patent number: 11191955Abstract: Devices, systems, and methods for accessing the internal and external tissues of the heart are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for localized delivery of substances to the heart tissue. In addition, various disclosed embodiments provide access to the internal surface of the heart for aspiration and delivery of substances to a targeted region without disturbing or interfering with nearby structures or surfaces.Type: GrantFiled: March 6, 2018Date of Patent: December 7, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Publication number: 20210346646Abstract: Devices, systems, and methods useful to engage tissue using suction and to perform medical procedures during sectional engagement. The present disclosure includes disclosure of a tension apparatus, comprising an elongated portion; and a head portion at a distal end of the elongated portion, the head portion comprising one or more arms, whereby a suction lumen extending along the elongated portion and the one or more arms terminates at one or more suction openings at each of the one or more arms.Type: ApplicationFiled: July 20, 2021Publication date: November 11, 2021Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Matthew Phillips
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Patent number: 11166703Abstract: Atrial appendage occlusion devices and methods of using the same that employ the application of light having a desired wavelength range. The devices of the present disclosure comprise a telescoping catheter assembly coupled with an adhesive delivery device and a suction source, and comprise at least one optical fiber disposed therein. The catheter assembly is configured to isolate an atrial appendage cavity, deliver suction and adhesive thereto, and, using the optical fiber(s), cure the adhesive present within the cavity all without withdrawing any components of the catheter assembly from the body. Methods for using such device in the treatment of atrial appendage occlusion are also provided.Type: GrantFiled: January 8, 2016Date of Patent: November 9, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Publication number: 20210316119Abstract: Engagement catheter devices, systems, and methods to use the same under suctional tissue engagement. A method of the present disclosure comprises the steps of engaging a targeted tissue under suction/vacuum using an engagement catheter, delivering a substance to, into, or through the targeted tissue from within a lumen of the engagement catheter, and injecting a fluid within a different lumen of the engagement catheter to flush the catheter and target tissue area with the fluid, and subsequently suctionally removing the injected fluid from the target area and lumens of the engagement catheter.Type: ApplicationFiled: June 22, 2021Publication date: October 14, 2021Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia
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Publication number: 20210307676Abstract: A non-invasive and minimally-invasive system and method of detecting iron content in nail and hair samples to diagnose iron deficiency anemia. The system comprises a portable and ultra sensitive magnetometer. A sample of hair or nail is collected from the patient and placed in the magnetometer. The magnetometer is sufficiently sensitive to detect or otherwise indicate the iron content of the sample. Diagnosis can be made based on the detected iron level.Type: ApplicationFiled: June 22, 2021Publication date: October 7, 2021Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Ali Dabiri
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Patent number: 11109772Abstract: Devices and methods are disclosed which relate to the detection of cardiovascular efficiency and risk of disease. The rate of volumetric change of the heart can be determined by measuring the parallel conductance across electrodes attached to the heart. Measurements from a lumen would consider the total conductance. The rate of volumetric or lumen cross-section area change can then be compared to an average model to determine the health of a patient.Type: GrantFiled: March 26, 2019Date of Patent: September 7, 2021Assignee: CVDevices, LLCInventor: Ghassan S. Kassab
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Patent number: 11103375Abstract: Devices and systems to fit around a tissue or organ and methods of using the same. In at least one embodiment of an implantable device of the present disclosure, the implantable device comprises a first engaging component comprising a first rigid inner plate at least partially surrounded by a first flexible coating, a second engaging component comprising a second rigid inner plate at least partially surrounded by a coating selected from the group consisting of the first flexible coating and the second flexible coating, a first c-ring and a second c-ring coupled to the engaging components, and a cover flap coupled to either the first engaging component or the second engaging component and capable of either further coupling to the second engaging component when initially coupled to the first engaging component or further coupling to the first engaging component when initially coupled to the second engaging component.Type: GrantFiled: May 29, 2018Date of Patent: August 31, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Thomas A. Kramer
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Patent number: 11065422Abstract: Devices, systems, and methods useful to engage tissue using suction and to perform medical procedures during sectional engagement. The present disclosure includes disclosure of a tension apparatus, comprising an elongated portion; and a head portion at a distal end of the elongated portion, the head portion comprising one or more arms, whereby a suction lumen extending along the elongated portion and the one or more arms terminates at one or more suction openings at each of the one or more arms.Type: GrantFiled: November 23, 2017Date of Patent: July 20, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Matthew Phillips, H. Toby Markowitz