Patents Assigned to CVDevices, LLC
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Publication number: 20210207463Abstract: Devices and systems for tissue engagement and methods of using the same.Type: ApplicationFiled: March 23, 2021Publication date: July 8, 2021Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Zachary Berwick, Matthew Phillips
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Publication number: 20210204979Abstract: Devices, systems, and methods for delivering a substance within a mammalian luminal organ or area adjacent thereto. In at least one exemplary embodiment of a system of the present disclosure, the system comprises an inner delivery device, comprising an inner portion configured to receive a substance therein, a pock tip at or near a distal end of the inner delivery device, the pock tip configured to deliver the substance from the inner portion, through a pock tip aperture defined within the pock tip, and into a mammalian tissue and/or luminal organ, and an embolus positioned within the inner portion, the embolus configured so that the substance remains distal to the embolus when the substance is positioned within the inner portion.Type: ApplicationFiled: November 17, 2020Publication date: July 8, 2021Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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Patent number: 11045300Abstract: Systems, devices, and methods for organ Retroperfusion along with regional mild hypothermia. One such system includes a hypothermia system including a hypothermia system outlet and a hypothermia system inlet; and a connector comprising a coolant inlet, a coolant outlet, a coolant reservoir, and a blood lumen, whereby the coolant inlet is configured to couple to the hypothermia system outlet and whereby the coolant outlet is configured to couple to the hypothermia system inlet; whereby a cooling product, when the hypothermia system is connected to the connector, can flow from the hypothermia system, through the hypothermia system outlet, into the coolant inlet, through the coolant reservoir, into the coolant outlet, and into the hypothermia system inlet, so that the cooling product can cool blood flowing through the blood lumen.Type: GrantFiled: April 2, 2018Date of Patent: June 29, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr., Zachary Berwick
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Patent number: 11040175Abstract: Engagement catheter devices, systems, and methods to use the same under suctional tissue engagement. A method of the present disclosure comprises the steps of engaging a targeted tissue under suction/vacuum using an engagement catheter, delivering a substance into or through the targeted tissue using a needle positioned within a first lumen of the engagement catheter, injecting a fluid within the first lumen of the engagement catheter to flush at least part of the first lumen with the fluid, and suctionally removing the injected fluid from within the first lumen of the engagement catheter.Type: GrantFiled: October 16, 2017Date of Patent: June 22, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Publication number: 20210161970Abstract: Methods and uses of biological tissues for various stent and other medical applications. In an exemplary embodiment of a method of processing a tissue of the present disclosure, the method comprises the steps of acquiring a mammalian tissue comprising at least a portion of a pulmonary region tissue, selecting a sample of pulmonary region tissue from the at least a portion of a pulmonary region tissue, and fixing the sample of pulmonary region tissue using a fixative, resulting in a fixed sample. In at least one embodiment, the step of selecting a sample of pulmonary region tissue comprises selecting a sample of pulmonary ligament tissue from the mammalian tissue.Type: ApplicationFiled: February 12, 2021Publication date: June 3, 2021Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR., Jorge Jordana, Zachary C. Berwick
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Patent number: 11013892Abstract: Steering engagement catheter devices, systems, and methods of using the same for accessing a tissue, including internal and external tissues of a heart, are disclosed. In at least one embodiment, a steering engagement catheter is provided, comprising an elongated tube having a proximal end, a distal end, and a first wall positioned circumferentially along a length of the elongated tube, the elongated tube configured such that a delivery catheter is capable of at least partial insertion into the elongated tube, at least one steering wire having a proximal end and a distal end, the distal end of the at least one steering wire coupled to the first wall of the elongated tube at or near the distal end of the elongated tube, and a controller operably coupled to the at least one steering wire at or near the proximal end of the at least one steering wire.Type: GrantFiled: February 27, 2018Date of Patent: May 25, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10952678Abstract: Devices and systems for tissue engagement and methods of using the same. In at least one embodiment of a device of the present disclosure, the device comprises an elongated body having a proximal end, a distal end, and at least one lumen extending from the proximal end to the distal end; an engagement portion at the distal end of the elongated body, the engagement portion configured to engage a tissue adjacent thereto when the engagement portion contacts the tissue while suction is applied through the device; and at least one electrode present along the engagement portion and configured to contact the tissue when the engagement portion contacts the tissue and to obtain bioimpedance data from the tissue while suction is applied through the device.Type: GrantFiled: April 27, 2017Date of Patent: March 23, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Zachary Berwick, Matthew Phillips
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Patent number: 10940167Abstract: Methods and uses of biological tissues for various stent and other medical applications. In an exemplary embodiment of a method of processing a tissue of the present disclosure, the method comprises the steps of acquiring a mammalian tissue comprising at least a portion of a pulmonary region tissue, selecting a sample of pulmonary region tissue from the at least a portion of a pulmonary region tissue, and fixing the sample of pulmonary region tissue using a fixative, resulting in a fixed sample. In at least one embodiment, the step of selecting a sample of pulmonary region tissue comprises selecting a sample of pulmonary ligament tissue from the mammalian tissue.Type: GrantFiled: February 11, 2013Date of Patent: March 9, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr., Jorge Jordana, Zachary C. Berwick
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Patent number: 10925491Abstract: Devices, systems, and methods for remotely monitoring physiologic cardiovascular data are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for the delivery of the sensor to the epicardial surface of the heart. In addition, various disclosed embodiments provide for a memory device capable of receiving the physiologic cardiovascular data collected by the sensors and transmitting such data wirelessly to a remote location.Type: GrantFiled: January 1, 2019Date of Patent: February 23, 2021Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Publication number: 20210007866Abstract: Deflection devices, systems, and methods for the prevention of stroke. Devices hereof comprise an extension portion and an anchor portion, both of which are configured to prevent the device from advancing into the artery extending from the aortic arch in which the device may be positioned. Additionally, a retrieval system is provided, the system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises one or more attachment portions configured to engage at least a portion of the anchor portion of a device positioned within an artery extending from the aortic arch.Type: ApplicationFiled: June 30, 2020Publication date: January 14, 2021Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Hyo Won Choi, Jose A. Navia, SR.
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Publication number: 20200405487Abstract: Methods and devices for controlling blood perfusion pressure along with regional mild hypothermia. In at least one embodiment of a device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, a partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel and to equalize the first blood pressure at the first area with the second blood pressure at the second area, and a regional hypothermia system operably coupled thereto, the regional hypothermia system operable to reduce and/or regulate a temperature of a bodily fluid flowing therethrough.Type: ApplicationFiled: July 7, 2020Publication date: December 31, 2020Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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Patent number: 10835285Abstract: Devices, systems, and methods for delivering a substance within a mammalian luminal organ or area adjacent thereto. In at least one exemplary embodiment of a system of the present disclosure, the system comprises an inner delivery device, comprising an inner portion configured to receive a substance therein, a pock tip at or near a distal end of the inner delivery device, the pock tip configured to deliver the substance from the inner portion, through a pock tip aperture defined within the pock tip, and into a mammalian tissue and/or luminal organ, and an embolus positioned within the inner portion, the embolus configured so that the substance remains distal to the embolus when the substance is positioned within the inner portion.Type: GrantFiled: January 23, 2018Date of Patent: November 17, 2020Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Publication number: 20200305947Abstract: Systems and methods for cryoablation of a tissue. In at least one embodiment of a cryoablation system of the present disclosure, the cryoablation system comprises an expandable stent comprising a proximal end and a distal end, a sidewall defining a lumen extending between the proximal end and the distal end, and a cryoablation chamber at the distal end, the expandable stent configured to permit blood flow therethrough, and a cryoablation device comprising at least one coolant tube at least partially positioned within the cryoablation chamber, wherein the at least one coolant tube is operable to produce a cryogenic environment sufficient to ablate at least a portion of a tissue engaged within the cryoablation chamber.Type: ApplicationFiled: January 28, 2020Publication date: October 1, 2020Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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Patent number: 10772636Abstract: Atrial appendage occlusion systems are provided, such systems including a first device and a second device. The first device has a first tube sized and shaped for insertion into the heart and a balloon coupled thereto. The second device has a second tube sized and shaped for insertion into a pericardial space surrounding the heart, and has a lumen extending at least partially from a second tube distal end to a second tube proximal end. The second device also includes a loop sized and shaped to fit at least partially within the lumen of the second tube, with the loop configured for protraction from the second tube distal end and for placement, and to be tightened and secured around, the atrial appendage.Type: GrantFiled: July 9, 2013Date of Patent: September 15, 2020Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10736729Abstract: Peripheral arterialization devices and methods of using the same. In an exemplary embodiment of a catheter for facilitating venous arterialization of the present disclosure, the catheter comprises an elongated body extending from a proximal end to a distal end and having a lumen defined therethrough along a longitudinal length of the elongated body, the elongated body configured to attach to a graft at or near the proximal end of the elongated body and further configured to permit fluid to flow through the graft, through the lumen, and out of one or more apertures defined within the elongated body at or near the distal end to facilitate venous arterialization upon at least partial implantation of the catheter into a vein of a patient.Type: GrantFiled: November 29, 2016Date of Patent: August 11, 2020Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10729525Abstract: Devices, system and methods for deforming body channels are disclosed herein. At least some embodiments described may be used to deform a body channel so as to decrease or prevent the normal intrachannel flow of material within the body channel. Such deformation may be used to treat such maladies as Gastroesophageal Reflux Disease.Type: GrantFiled: January 2, 2018Date of Patent: August 4, 2020Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10702387Abstract: Methods and devices for controlling blood perfusion pressure along with regional mild hypothermia. In at least one embodiment of a device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, a partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel and to equalize the first blood pressure at the first area with the second blood pressure at the second area, and a regional hypothermia system operably coupled thereto, the regional hypothermia system operable to reduce and/or regulate a temperature of a bodily fluid flowing therethrough.Type: GrantFiled: June 12, 2017Date of Patent: July 7, 2020Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10695199Abstract: Deflection devices, systems, and methods for the prevention of stroke. Devices hereof comprise an extension portion and an anchor portion, both of which are configured to prevent the device from advancing into the artery extending from the aortic arch in which the device may be positioned. Additionally, a retrieval system is provided, the system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises one or more attachment portions configured to engage at least a portion of the anchor portion of a device positioned within an artery extending from the aortic arch.Type: GrantFiled: May 2, 2017Date of Patent: June 30, 2020Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Hyo Won Choi, Jose A. Navia, Sr.
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Publication number: 20200155817Abstract: Systems and methods for selective auto-retroperfusion along with regional mild hypothermia.Type: ApplicationFiled: October 22, 2019Publication date: May 21, 2020Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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Patent number: 10588763Abstract: Devices, systems, and methods for the prevention of stroke. Devices and systems hereof comprise stents configured to fit within at least part of an artery extending from an aortic arch, and at least one component comprising struts for diverting emboli from entering an artery when the component is positioned at or near its ostium. The stents and the deflection component(s) are coupled in a linked configuration. Additionally, a retrieval system and methods of using the same are provided, the retrieval system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises an attachment portion configured to engage a device positioned within an artery extending from the aortic arch.Type: GrantFiled: June 20, 2017Date of Patent: March 17, 2020Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Hyo Won Choi, Jose A. Navia, Sr.