Patents Assigned to CVDevices, LLC
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Publication number: 20200046396Abstract: Thrombectomy systems and devices and methods of using the same. In an exemplary embodiment of a thrombectomy system of the present disclosure, the thrombectomy system comprises a thrombectomy sheath, comprising a circumferential outer wall reinforced with a reinforcement, configured as an elongated tube having a lumen therethrough; and a sonovisible element positioned at or near a distal end of the circumferential outer wall; wherein the thrombectomy sheath is sized and shaped to be at least partially positioned within a vein proximal to a thrombus or other item within the vein and further configured to expand to contact the vein to secure the thrombectomy sheath within the vein; and wherein the lumen is sized and shaped to receive a device selected from the group consisting of a balloon catheter and a snare having a loop.Type: ApplicationFiled: October 8, 2019Publication date: February 13, 2020Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Seshadri Raju
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Patent number: 10555767Abstract: Devices, systems, and methods for valve removal. In an embodiment of an umbrella device for removing a valve of the present disclosure, the umbrella device comprises an elongated shaft having a distal end, a first umbrella comprising a first mesh, the first umbrella coupled to the shaft at or near the distal end of the shaft, a second umbrella comprising a second mesh, the second umbrella coupled to the shaft proximal to the first umbrella, and a mechanical drill rotatably coupled to the shaft and positioned between the first umbrella and the second umbrella.Type: GrantFiled: November 29, 2016Date of Patent: February 11, 2020Assignee: CVDevices, LLCInventor: Ghassan S. Kassab
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Patent number: 10543033Abstract: Systems and methods for cryoablation of a tissue. In at least one embodiment of a cryoablation system of the present disclosure, the cryoablation system comprises an expandable stent comprising a proximal end and a distal end, a sidewall defining a lumen extending between the proximal end and the distal end, and a cryoablation chamber at the distal end, the expandable stent configured to permit blood flow therethrough, and a cryoablation device comprising at least one coolant tube at least partially positioned within the cryoablation chamber, wherein the at least one coolant tube is operable to produce a cryogenic environment sufficient to ablate at least a portion of a tissue engaged within the cryoablation chamber.Type: GrantFiled: August 15, 2017Date of Patent: January 28, 2020Assignee: CVDEVICES, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10499924Abstract: Devices, systems, and methods are disclosed for inverting and closing a left atrial appendage. Certain methods include the steps of inverting a distal portion of a left atrial appendage and constraining the inverted portion using at least a snare device configured to be fit around the inverted portion of the left atrial appendage and closed, so that the inverted portion is securely circumscribed and closed. Devices and systems related to such methods are also described and include a catheter system comprising a vacuum tube and a snare slidably disposed within a catheter.Type: GrantFiled: April 29, 2015Date of Patent: December 10, 2019Assignee: CVDevices, LLCInventor: Ghassan S. Kassab
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Publication number: 20190351127Abstract: Unitary body systems and devices and methods to use the same for retroperfusion. In an exemplary device embodiment of the present disclosure, the device comprises a unitary body having a wall and a lumen defined therethrough, a first portion terminating at a first end and configured for at least partial placement within a mammalian artery, a first valve positioned at or near an end of the first portion opposite the first end, a second portion terminating at a second end and configured for at least partial placement within a mammalian vein, and a second valve positioned at or near an end of the second portion opposite the second end.Type: ApplicationFiled: July 30, 2019Publication date: November 21, 2019Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Hyo Won Choi
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Publication number: 20190343618Abstract: Endoprosthesis assemblies and methods for using the same. In at least one embodiment, the endoprosthesis assembly comprises an endoprosthesis comprising an impermeable inner wall defining an endoprosthesis lumen sized and shaped to permit fluid to flow therethrough, a distal balloon positioned at or near a distal end of the endoprosthesis and capable of inflation to anchor the distal end of the endoprosthesis within a luminal organ, and a proximal balloon positioned at or near a proximal end of the endoprosthesis and capable of inflation to anchor the proximal end of the endoprosthesis within the luminal organ, wherein when the endoprosthesis assembly is positioned within the luminal organ at or near an aneurysm sac, inflation of the distal balloon and the proximal balloon effectively isolates the aneurysm sac and prevents fluid within the aneurysm sac from flowing past the distal balloon and the proximal balloon.Type: ApplicationFiled: April 16, 2019Publication date: November 14, 2019Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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Patent number: 10470903Abstract: The disclosure of the present application provides devices, systems, and methods for the prevention of stroke. In at least one embodiment of a device of the present application, the device comprises an extension portion sized and shaped to fit within an artery extending from an aortic arch, and a flange portion sized and shaped to prevent the device from advancing into the artery extending from the aortic arch in which the device may be positioned. In at least one embodiment of a system for preventing stroke of the present application, the system comprises a hypotube, a folder coupled to a distal end of the hypotube, a sleeve positioned circumferentially around the hypotube proximal to the folder, and a stent, wherein a first part of the stent may be positioned within the folder, and wherein a second part of the stent may be positioned within the sleeve.Type: GrantFiled: December 13, 2016Date of Patent: November 12, 2019Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr., Jorge Jordana
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Publication number: 20190336136Abstract: Methods and systems for inverting and closing a left atrial appendage. The system can include a vacuum tube, closed-end needle, and tissue glue. The vacuum tube may have a plunger-like end for attachment to the left atrial appendage and may also be capable attaching to a vacuum source. The method can comprise the steps of attaching the vacuum tube to the left atrial appendage, advancing a closed-end needle through the left atrial appendage, retracting the vacuum tube to invert the left atrial appendage, and injecting tissue glue through the closed-end needle so that the exterior sides of the left atrial appendage are glued together and the appendage will fibrous and atrophy over time, thereby eliminating formation of a thrombus within the apex of the atrial appendage.Type: ApplicationFiled: July 16, 2019Publication date: November 7, 2019Applicants: CVDevices, LLCInventor: Ghassan S. Kassab
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Patent number: 10449337Abstract: Systems and methods for selective auto-retroperfusion along with regional mild hypothermia.Type: GrantFiled: August 8, 2017Date of Patent: October 22, 2019Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10433867Abstract: Thrombectomy systems and devices and methods of using the same. In an exemplary embodiment of a thrombectomy system of the present disclosure, the thrombectomy system comprises a thrombectomy sheath, comprising a circumferential outer wall reinforced with a reinforcement, configured as an elongated tube having a lumen therethrough; and a sonovisible element positioned at or near a distal end of the circumferential outer wall; wherein the thrombectomy sheath is sized and shaped to be at least partially positioned within a vein proximal to a thrombus or other item within the vein and further configured to expand to contact the vein to secure the thrombectomy sheath within the vein; and wherein the lumen is sized and shaped to receive a device selected from the group consisting of a balloon catheter and a snare having a loop.Type: GrantFiled: August 1, 2016Date of Patent: October 8, 2019Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Seshadri Raju
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Patent number: 10390984Abstract: Devices and systems to fit around a tissue or organ and methods of using the same. In at least one embodiment of an implantable device of the present disclosure, the implantable device comprises a first engaging component comprising a first rigid inner plate at least partially surrounded by a first flexible coating, a second engaging component comprising a second rigid inner plate at least partially surrounded by a coating selected from the group consisting of the first flexible coating and the second flexible coating, a first c-ring and a second c-ring coupled to the engaging components, and a cover flap coupled to either the first engaging component or the second engaging component and capable of either further coupling to the second engaging component when initially coupled to the first engaging component or further coupling to the first engaging component when initially coupled to the second engaging component.Type: GrantFiled: July 28, 2015Date of Patent: August 27, 2019Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10363354Abstract: Unitary body systems and devices and methods to use the same for retroperfusion. In an exemplary device embodiment of the present disclosure, the device comprises a unitary body having a wall and a lumen defined therethrough, a first portion terminating at a first end and configured for at least partial placement within a mammalian artery, a first one-way valve positioned at or near an end of the first portion opposite the first end, a second portion terminating at a second end and configured for at least partial placement within a mammalian vein, and a second one-way valve positioned at or near an end of the second portion opposite the second end.Type: GrantFiled: July 31, 2014Date of Patent: July 30, 2019Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Hyo Won Choi
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Publication number: 20190216461Abstract: A device and system are described that are capable of isolating at least one targeted tissue and forming an anastomosis between two internal body structures though a completely endoscopic procedure. Further, the device and system described generally comprise two tubular members that are capable of moving in a telescopic fashion relative to one another. Additionally, a method is described for using the device and/or system to bypass the duodenum from digestion.Type: ApplicationFiled: March 26, 2019Publication date: July 18, 2019Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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Publication number: 20190216357Abstract: Devices and methods are disclosed which relate to the detection of cardiovascular efficiency and risk of disease. The rate of volumetric change of the heart can be determined by measuring the parallel conductance across electrodes attached to the heart. Measurements from a lumen would consider the total conductance. The rate of volumetric or lumen cross-section area change can then be compared to an average model to determine the health of a patient.Type: ApplicationFiled: March 26, 2019Publication date: July 18, 2019Applicant: CVDevices, LLCInventor: Ghassan S. Kassab
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Publication number: 20190209010Abstract: Devices, systems, and methods for remotely monitoring physiologic cardiovascular data are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for the delivery of the sensor to the epicardial surface of the heart. In addition, various disclosed embodiments provide for a memory device capable of receiving the physiologic cardiovascular data collected by the sensors and transmitting such data wirelessly to a remote location.Type: ApplicationFiled: January 1, 2019Publication date: July 11, 2019Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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Publication number: 20190192754Abstract: Devices and methods for assisting cardiac function. In an exemplary embodiment of a device for assisting heart function of the present disclosure, the device comprises a first plate and an opposing second plate, each plate having an inner surface, a cardiac processor coupled to at least one of the first plate and the second plate, a bladder having an inner chamber and disposed between the inner surfaces, and a first catheter having a proximal end in communication with the inner chamber of the bladder and a distal end having a first pericardial balloon coupled thereto, wherein a gas and/or a liquid within the inner chamber of the bladder can be injected into the first pericardial balloon upon compression of the first plate relative to the second plate, and wherein the gas and/or the liquid can be removed from the first pericardial balloon upon retraction of the first plate relative to the second plate.Type: ApplicationFiled: November 6, 2018Publication date: June 27, 2019Applicant: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, SR.
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DEVICES, SYSTEMS, AND METHODS TO PRECONDITION, ARTERIALIZE, AND/OR OCCLUDE A MAMMALIAN LUMINAL ORGAN
Publication number: 20190150937Abstract: Devices, systems, and methods to precondition, arterialize, and/or occlude a mammalian luminal organ. In an exemplary embodiment of a device for preconditioning, arterializing, and/or occluding a mammalian luminal organ of the present disclosure, the device comprises a frame comprising a plurality of struts, wherein at least one strut of the plurality of struts forms a local general perimeter or boundary of the device, and an expandable occluder coupled to the frame and comprising a membrane or other expandable material that can generally expand and/or unfold as device shifts from a first configuration to a second configuration.Type: ApplicationFiled: January 24, 2019Publication date: May 23, 2019Applicant: CVDevices, LLCInventor: Ghassan S. Kassab -
Patent number: 10285814Abstract: Devices and methods for controlling blood perfusion pressure. In an exemplary device for controlling blood perfusion pressure within a vessel of the present disclosure, the device comprises an elongated body having a lumen, a proximal end configured for placement in a first area having a first blood pressure, and a distal end configured for placement in a second area having a second blood pressure, partial occluder positioned within the lumen of the elongated body between the proximal end and the distal end, the partial occluder configured so not to fully occlude a blood vessel, wherein the partial occluder is configured to equalize the first blood pressure at the first area with the second blood pressure at the second area.Type: GrantFiled: February 28, 2017Date of Patent: May 14, 2019Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10258458Abstract: Endoprosthesis assemblies and methods for using the same. In at least one embodiment, the endoprosthesis assembly comprises an endoprosthesis comprising an impermeable inner wall defining an endoprosthesis lumen sized and shaped to permit fluid to flow therethrough, a distal balloon positioned at or near a distal end of the endoprosthesis and capable of inflation to anchor the distal end of the endoprosthesis within a luminal organ, and a proximal balloon positioned at or near a proximal end of the endoprosthesis and capable of inflation to anchor the proximal end of the endoprosthesis within the luminal organ, wherein when the endoprosthesis assembly is positioned within the luminal organ at or near an aneurysm sac, inflation of the distal balloon and the proximal balloon effectively isolates the aneurysm sac and prevents fluid within the aneurysm sac from flowing past the distal balloon and the proximal balloon.Type: GrantFiled: July 11, 2017Date of Patent: April 16, 2019Assignee: CVDevices, LLCInventors: Ghassan S. Kassab, Jose A. Navia, Sr.
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Patent number: 10245049Abstract: Thrombus removal systems and devices and methods of using the same. In an exemplary embodiment of a thrombus removal system of the present disclosure, the thrombus removal system comprises an umbrella catheter comprising an umbrella catheter tube and an umbrella positioned at least partially within the umbrella catheter tube when in a compressed configuration and positioned external to the umbrella catheter tube when in a deployed configuration, and a balloon catheter configured to fit around at least part of the umbrella catheter, the balloon catheter comprising a balloon catheter tube and a balloon coupled thereto, the balloon capable of inflation within a lumen of a mammalian vessel to substantially or completely occlude the lumen of the mammalian vessel, wherein the thrombus removal system is configured to disrupt and/or dissolve and remove at least a portion of a thrombus positioned within the lumen of the mammalian vessel.Type: GrantFiled: June 8, 2012Date of Patent: April 2, 2019Assignee: CVDevices, LLCInventor: Ghassan S. Kassab