Abstract: A method of providing a sleep apnea nerve stimulation therapy to a subject may include detecting a respiratory waveform of the subject with a sensor. The sensor may be configured for coupling to the subject. The respiratory waveform may include a plurality of respiratory cycles each corresponding to at least one of a breath and an attempted breath of the subject. The method may also include identifying a breathing pattern within the respiratory waveform over a period of time. The breathing pattern may include a repeating pattern of a plurality of respiratory cycles followed by at least one respiratory cycle corresponding to a disordered breathing event. The method may also include generating a series of stimulation pulses with an implantable nerve stimulator configured for coupling to a hypoglossal nerve of the subject. The series of stimulation pulses may be coordinated with the breathing pattern.

Abstract: A method includes detecting a counter event at a system monitor of a system. The method also includes, in response to detecting the counter event, checking a state of each flag of a first set of flags. Each of the first set of flags is associated with a monitored module of the system, and the state of each of the first set of flags is indicated by a value at a memory location that is enabled. The method also includes, in response to determining that at least one flag of the first set of flags has a value indicating an error associated with a particular monitored module, causing an action to be performed at the system.

Abstract: An implantable medical device includes a case having a conductive housing defining an opening. A dielectric material is coupled to the conductive housing to hermetically seal the opening. A header block is coupled to the case over the dielectric material. An antenna is within the case under the dielectric material and there is no antenna feedthrough extending through the case into the header block.

Abstract: A particular implantable device may include an antenna configured to receive a far field radiative signal. The implantable device may also include a voltage rectifier configured to rectify the far field radiative signal received by the antenna to provide a rectified voltage signal. The implantable device may further include a charge storage element operative to receive the rectified voltage signal and to store charge responsive to the rectified voltage signal. The implantable device may also include a stimulation module powered by the charge storage element. The stimulation module may be operative to generate an electrical stimulation signal to stimulate a target nerve of a patient. The implantable medical device may further include a nerve wrap configured to house the voltage rectifier, the charge storage element, and the stimulation module. The nerve wrap may include one or more electrodes operative to deliver the electrical stimulation signal to the target nerve.

Abstract: A method includes determining sleep cycle information related to a sleep cycle of a patient based on body parameter data. The method also includes adjusting a cranial nerve stimulation parameter based on the sleep cycle information.

Abstract: A method of detecting a subject's physiological status, seizure state, or seizure type with limb-based accelerometers identifying a favored accelerometer or limb that provides a better sensitivity or false positive rate as compared to other accelerometers or limbs. The detection method may include determining whether the seizure conforms with an anticipated seizure type, and determining whether to base a seizure detection on data from the favored or un-favored accelerometers or limbs. The method may also include applying a weighing factor to base the detection on data obtained primarily from the favored accelerometer or limb or to not rely on data obtained primarily from un-favored accelerometers or limbs. The method may also include comparing data obtained from a favored accelerometer or limb with data obtained from other accelerometers or limbs or obtained from detection devices using ECG or EEG. An alert may be generated based on the detection of a seizure.

Abstract: A motion monitoring system and a method of obtaining and analyzing motion data that uses an accelerometer or an image capture device to acquire subject motion data. The motion data may be obtained from an accelerometer applied to a chest of the subject, or from an image capture device configured to view the subject during the detected motion. The motion data is analyzed to distinguish between a seizure type of motion and a non-seizure type of motion, with the subject motion characterized by at least one of, and combinations of, motion amplitude or magnitude, motion period or frequency, motion bandwidth, subject position, and subject change in position over a time period of the detected motion. The system and method further includes the generation of an output in response to an identification of the seizure and non-seizure types of motion.

Abstract: The present invention provides systems and methods for managing epilepsy. In one embodiment, a method of the present invention characterize a patient's propensity for a future epileptic seizure and communicates to the patient and/or a health care provider a therapy recommendation. The therapy recommendation is typically a function of the patient's propensity for the future epileptic seizure.

Abstract: The present invention provides a closed-loop system for treating neurological disorders, such as epilepsy. In one embodiment the system comprises an input assembly that is adapted to receive one or more signals from a patient that are indicative of a patient's neurological state. The input assembly processes the one or more signals to generate one or more control input signals. An output assembly receives the one or more control input signals from the input assembly and generate a neuromodulation signal that is a function of the patient's neurological state. An electrode array is configured to deliver the neuromodulation signal to a patient's peripheral nerve, such as the vagus nerve.

Abstract: This disclosure relates to devices, systems, and methods for validating locational data for a monitoring device. The external monitoring device located on a patient may include one or more processors, one or more memory devices, one or more power devices, one or more heart rate detection devices, and one or more heart sound detection devices. Further, the method may include determining a plurality of status of an external monitoring device located on a patient via one or more processors based on obtained heart rate data and obtained heart sound data. The external monitoring device state may be generated via a validation module based on the heart rate data and the heart sound data.

Abstract: A method includes determining a measurement indicative of a synchrony between one or more regions of a patient's autonomic nervous system (e.g., the NTS) and one or more regions of the patient's central nervous system (e.g., the thalamus, the cortex) based on body parameter data. The method also includes adjusting a cranial nerve stimulation parameter based on the measurement.

Abstract: Systems and methods to treat a pulmonary disorder are provided. A particular method includes positioning an electrode in a patient's body at a location proximate a branch of a vagus nerve. The branch of the vagus nerve includes at least one of a bronchial branch of the vagus nerve and a pulmonary plexus. The method also includes activating the electrode such that energy is delivered from the electrode to the branch of the vagus nerve so as to block intrinsic neural activity in the branch of the vagus nerve to treat the pulmonary disorder.

Abstract: An implantable medical device charging apparatus includes a charging circuit. The charging circuit includes a series resonator responsive to a signal applied to the charging circuit. During operation, the series resonator inductively couples to a secondary coil within an implantable medical device to transfer energy to the secondary coil. The charging circuit also includes a parallel resonator coupled to the series resonator. The parallel resonator filters a first component of the signal from propagating to the series resonator.

Abstract: A method includes detecting a counter event at a system monitor of a system. The method also includes, in response to detecting the counter event, checking a state of each flag of a first set of flags. Each of the first set of flags is associated with a monitored module of the system, and the state of each of the first set of flags is indicated by a value at a memory location that is enabled. The method also includes, in response to determining that at least one flag of the first set of flags has a value indicating an error associated with a particular monitored module, causing an action to be performed at the system.

Abstract: An implantable medical device includes a housing. An opening is present in the housing. The implantable medical device includes communication circuitry in the housing. The implantable medical device includes a cover coupled to edges of the housing defining the opening to substantially close the opening. The implantable medical device also includes an antenna coupled to the cover. The antenna is electrically coupled to the communication circuitry.

Abstract: A method includes determining sleep cycle information related to a sleep cycle of a patient based on body parameter data. The method also includes adjusting a cranial nerve stimulation parameter based on the sleep cycle information.

Abstract: The present invention provides systems and methods for managing epilepsy. In one embodiment, a method of the present invention characterize a patient's propensity for a future epileptic seizure and communicates to the patient and/or a health care provider a therapy recommendation. The therapy recommendation is typically a function of the patient's propensity for the future epileptic seizure.

Abstract: A system and method for estimating the longevity of an implantable medical device (IMD). In one embodiment of a method for estimating a life of a power source of an implantable medical device, a first life estimate of the power source is determined based on a first open-loop value corresponding to an open-loop parameter for open-loop therapy delivery, a first closed loop value corresponding to a closed-loop parameter for closed-loop therapy delivery, and prior usage data corresponding to prior therapy delivery. The first life estimate of the power source is displayed. The first life estimate displayed includes a first open-loop portion associated with open-loop therapy delivery and a first closed-loop portion associated with closed-loop therapy delivery.

Abstract: A method of treating a patient, comprising: sensing a biological parameter indicative of respiration; analyzing the biological parameter to identify a respiratory cycle; identifying an inspiratory phase of the respiratory cycle; and delivering stimulation to a hypoglossal nerve of the patient, wherein stimulation is delivered if a duration of the inspiratory phase of the respiratory cycle is greater than a predetermined portion of a duration of the entire respiratory cycle.

Abstract: A particular method of providing power to an implantable medical device includes providing a first signal to a primary coil that is inductively coupled to a secondary coil of an implantable medical device. The method also include determining a first alignment difference between a voltage corresponding to the first signal and at least one of a current corresponding to the first signal and a component voltage at a component of a primary coil circuit. The method further includes determining a frequency sweep range based on the first alignment difference. The method also includes performing a frequency sweep over the frequency sweep range.