Patents Assigned to Cytokinetics, Inc.
  • Motor proteins and methods for their use
    Patent number: 6429005
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif12a, antibodies to HsKif12a, methods of screening for HsKif12a modulators using biologically active HsKif12a, and kits for screening for HsKif12a modulators.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: August 6, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Screening assays for modulators of human kinesin protein HsKif21b
    Patent number: 6426193
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif21b, antibodies to HsKif21b, methods of screening for HsKif21b modulators using biologically active HsKif21b, and kits for screening for HsKif21b modulators.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: July 30, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Motor proteins and methods for their use
    Patent number: 6426207
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif12a, antibodies to HsKif12a, methods of screening for HsKif12a modulators using biologically active HsKif12a, and kits for screening for HsKif12a modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: July 30, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Nucleic acids encoding hskif16a, a kinesin motor protein
    Patent number: 6420162
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif16a, antibodies to HsKif16a, methods of screening for HsKif16a modulators using biologically active HsKif16a, and kits for screening for HsKif16a modulators.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: July 16, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Screening assays for modulators of human kinesin protein HsKif6
    Patent number: 6416966
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif6, antibodies to HsKif6, methods of screening for HsKif6 modulators using biologically active HsKif6, and kits for screening for HsKif6 modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: July 9, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Human kinesin protein KSP
    Patent number: 6414121
    Abstract: Described herein are methods that can be used for diagnosis and prognosis of cellular proliferation. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate cellular proliferation. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in cancers are described.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: July 2, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Kenneth W. Wood, Jeffrey T. Finer, Christophe Beraud, John Mak, Roman Sakowicz
  • Aspergillus fumigatus profilin
    Patent number: 6403372
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of A. fumigatus profilin, methods of screening for A. fumigatus profilin modulators using biologically active A. fumigatus profilin, and kits for screening for A. fumigatus profilin modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: June 11, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Corey E. Nislow, Kee Wong
  • Human kinesin-like protein HsKif16b
    Patent number: 6399346
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif16b, antibodies to HsKif16b, methods of screening for HsKif16b modulators using biologically active HsKif16b, and kits for screening for HsKif16b modulators.
    Type: Grant
    Filed: November 24, 2000
    Date of Patent: June 4, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Motor proteins and methods for their use
    Patent number: 6395527
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif7, antibodies to HsKif7, methods of screening for HsKif7 modulators using biologically active HsKif7, and kits for screening for HsKif7 modulators.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: May 28, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Nucleic acids encoding HsKifC2, a kinesin motor protein
    Patent number: 6395540
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKifC2, antibodies to HsKifC2, methods of screening for HsKifC2 modulators using biologically active HsKifC2, and kits for screening for HsKifC2 modulators.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: May 28, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Motor proteins and methods for their use
    Patent number: 6391601
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKip3d, antibodies to HsKip3d, methods of screening for HsKip3d modulators using biologically active HsKip3d, and kits for screening for HsKip3d modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: May 21, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Screening assays for modulators of human kinesin protein HSKIP3B
    Patent number: 6391573
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKip3b, antibodies to HsKip3b, methods of screening for HsKip3b modulators using biologically active HsKip3b, and kits for screening for HsKip3b modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: May 21, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Motor proteins and methods for their use
    Patent number: 6391613
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif15, antibodies to HsKif15, methods of screening for HsKif15 modulators using biologically active HsKif15, and kits for screening for HsKif15 modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: May 21, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Roman Sakowicz, Kenneth W. Wood
  • Motor proteins and method for their use
    Patent number: 6387679
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif9, antibodies to HsKif9, methods of screening for HsKif9 modulators using biologically active HsKif9, and kits for screening for HsKif9 modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: May 14, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Motor proteins and methods for their use
    Patent number: 6387644
    Abstract: The present invention provides high throughput screening systems for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: May 14, 2002
    Assignee: Cytokinetics, Inc.
    Inventor: Christophe Beraud
  • Nucleic acids encoding HSKIF21B, a kinesin motor protein
    Patent number: 6383796
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif21b, antibodies to HsKif21b, methods of screening for HsKif21b modulators using biologically active HsKif21b, and kits for screening for HsKif21b modulators.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: May 7, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Human kinesin-related protein HsKrp5
    Patent number: 6379941
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKrp5, antibodies to HsKrp5, methods of screening for HsKrp5 modulators using biologically active HsKrp5, and kits for screening for HsKrp5 modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: April 30, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman
  • Motor proteins and method for their use
    Patent number: 6379912
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif15, antibodies to HsKif15, methods of screening for HsKif15 modulators using biologically active HsKif15, and kits for screening for HsKif15 modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: April 30, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Roman Sakowicz, Kenneth W. Wood
  • Image analysis for phenotyping sets of mutant cells
    Publication number: 20020049544
    Abstract: A method described herein phenotypes a set of mutant strains in a quantitative manner. Specifically, the method characterizes a cellular and subcellular architecture of mutant alleles grown in a variety of conditions using various morphological and molecular markers, combined with automated image acquisition and analysis. Phenotypic features may include the cytoskeleton, organelles, cell morphology, DNA replication state, the relationship of these features to each other, etc. From these features a quantitative “fingerprint” can be generated for each phenotype. This quantitative phenotypic information is made available in a database that links genotype to phenotype. Genes characterized in this manner may be clustered into functional categories, pathways, higher order protein assemblies, and the like.
    Type: Application
    Filed: June 22, 2001
    Publication date: April 25, 2002
    Applicant: Cytokinetics, Inc.
    Inventors: Corey E. Nislow, Nolan H. Sigal, David G. Drubin, Cynthia L. Adams
  • Human kinesin-related protein HsKip3b
    Patent number: 6368841
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKip3b, antibodies to HsKip3b, methods of screening for HsKip3b modulators using biologically active HsKip3b, and kits for screening for HsKip3b modulators.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: April 9, 2002
    Assignee: Cytokinetics, Inc.
    Inventors: Christophe Beraud, Richard Freedman