Abstract: The present invention provides high throughput screening systems for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif16b, antibodies to HsKif16b, methods of screening for HsKif16b modulators using biologically active HsKif16b, and kits for screening for HsKif16b modulators.
Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif15, antibodies to HsKif15, methods of screening for HsKif15 modulators using biologically active HsKif15, and kits for screening for HsKif15 modulators.
Type:
Grant
Filed:
May 17, 2000
Date of Patent:
March 12, 2002
Assignee:
Cytokinetics, Inc.
Inventors:
Christophe Beraud, Roman Sakowicz, Kenneth W. Wood
Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif9, antibodies to HsKif9, methods of screening for HsKif9 modulators using biologically active HsKif9, and kits for screening for HsKif9 modulators.
Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif6, antibodies to HsKif6, methods of screening for HsKif6 modulators using biologically active HsKif6, and kits for screening for HsKif6 modulators.
Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKifC2, antibodies to HsKifC2, methods of screening for HsKifC2 modulators using biologically active HsKifC2, and kits for screening for HsKifC2 modulators.
Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif16a, antibodies to HsKif16a, methods of screening for HsKif16a modulators using biologically active HsKif16a, and kits for screening for HsKif16a modulators.
Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKif9, antibodies to HsKif9, methods of screening for HsKif9 modulators using biologically active HsKif9, and kits for screening for HsKif9 modulators.
Abstract: The present invention provides high throughput screening systems for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
Abstract: The invention provides isolated nucleic acid and amino acid sequences of HsKip3b, antibodies to HsKip3b, methods of screening for HsKip3b modulators using biologically active HsKip3b, and kits for screening for HsKip3b modulators.
Abstract: The present invention provides high throughput screening systems for identifying antifungal compounds. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
Type:
Grant
Filed:
April 3, 2000
Date of Patent:
September 4, 2001
Assignee:
Cytokinetics, Inc.
Inventors:
Corey E. Nislow, Roman Sakowicz, Christophe Beraud
Abstract: Disclosed is a process for growing living cellular material in a reaction zone having a membrane in contact with an aqueous medium. The concentration of nutrient in samples from the process is measured using a spectrometric instrument to obtain spectral data characteristic of nutrient components. This spectral data is analyzed using a chi-squared mathematical technique to determine the unknown concentration of nutrient components in said samples. Then the rate at which nutrient is fed to the reaction zone is altered based on the determination of concentration of nutrient components as required to optimize the process.
Type:
Grant
Filed:
November 12, 1993
Date of Patent:
April 9, 1996
Assignees:
Cytokinetics, Inc., Applied Power Concepts, Inc.