Patents Assigned to Cytori Therapeutics, Inc.
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Patent number: 10119113Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.Type: GrantFiled: October 12, 2015Date of Patent: November 6, 2018Assignee: CYTORI THERAPEUTICS, INC.Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Ronda Elizabeth Schreiber, Isabella Wulur
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Patent number: 9872877Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: GrantFiled: July 6, 2016Date of Patent: January 23, 2018Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Patent number: 9849149Abstract: Cells present in adipose tissue are used to treat patients, including patients with PVD and related diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: GrantFiled: December 11, 2014Date of Patent: December 26, 2017Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Patent number: 9597395Abstract: Adipose derived regenerative cells are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells, e.g., stem and/or progenitor cells, obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, adipose derived regenerative cells are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit.Type: GrantFiled: May 25, 2005Date of Patent: March 21, 2017Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Min Zhu, Brian M. Strem, Eric Daniels, Isabella Wulur
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Patent number: 9511094Abstract: Cells present in adipose tissue are used to stroke and stroke related diseases and disorders in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: GrantFiled: August 15, 2012Date of Patent: December 6, 2016Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Brian M. Strem
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Patent number: 9511096Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: GrantFiled: February 14, 2014Date of Patent: December 6, 2016Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Methods of using adipose derived regenerative cells in the treatment of renal diseases and disorders
Patent number: 9504718Abstract: Cells present in processed lipoaspirate tissue are used to treat patients, including patients with renal conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic renal benefit.Type: GrantFiled: March 25, 2013Date of Patent: November 29, 2016Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels -
Patent number: 9504716Abstract: Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, regenerative cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic musculoskeletal benefit.Type: GrantFiled: August 9, 2010Date of Patent: November 29, 2016Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser, Susan Lynn Riley, Ronda Elizabeth Schreiber
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Patent number: 9492483Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: GrantFiled: February 14, 2014Date of Patent: November 15, 2016Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Patent number: 9486484Abstract: Aspects of the invention provides methods for preparing and using adipose-tissue-derived stem and progenitor cells, adipose-tissue-derived lymphatic endothelial cells, and cells capable of differentiating into lymphatic endothelial cells to treat disorders of the lymphatic system and to modulate expansion, repair, and/or regeneration of the lymphatic system. The invention further provides using adipose-tissue-derived lymphatic endothelial cells and cells capable of differentiating into lymphatic endothelial cells for delivery of therapeutic agents to tumor cells as a means for treating malignant disease, and assays to screen for drugs that modulate lymphatic system expansion, repair or regeneration.Type: GrantFiled: July 21, 2014Date of Patent: November 8, 2016Assignee: Cytori Therapeutics, Inc.Inventors: Zeni Alfonso, John K. Fraser
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Patent number: 9480718Abstract: Cells present in adipose tissue are used to treat patients, including patients with PVD and related diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: GrantFiled: August 16, 2012Date of Patent: November 1, 2016Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Patent number: 9463203Abstract: Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, regenerative cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic musculoskeletal benefit.Type: GrantFiled: August 18, 2014Date of Patent: October 11, 2016Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser, Susan L. Riley, Ronda E. Schreiber
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Patent number: 9198937Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: December 21, 2012Date of Patent: December 1, 2015Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick
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Patent number: 8883499Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.Type: GrantFiled: April 20, 2012Date of Patent: November 11, 2014Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Ronda Elizabeth Schreiber, Isabella Wulur
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Publication number: 20140227234Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: ApplicationFiled: February 14, 2014Publication date: August 14, 2014Applicant: CYTORI THERAPEUTICS, INC.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Publication number: 20140227341Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: ApplicationFiled: February 14, 2014Publication date: August 14, 2014Applicant: CYTORI THERAPEUTICS, INC.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Patent number: 8784801Abstract: Aspects of the invention provides methods for preparing and using adipose-tissue-derived stem and progenitor cells, adipose-tissue-derived lymphatic endothelial cells, and cells capable of differentiating into lymphatic endothelial cells to treat disorders of the lymphatic system and to modulate expansion, repair, and/or regeneration of the lymphatic system. The invention further provides using adipose-tissue-derived lymphatic endothelial cells and cells capable of differentiating into lymphatic endothelial cells for delivery of therapeutic agents to tumor cells as a means for treating malignant disease, and assays to screen for drugs that modulate lymphatic system expansion, repair or regeneration.Type: GrantFiled: February 18, 2011Date of Patent: July 22, 2014Assignee: Cytori Therapeutics, Inc.Inventors: Zeni Alfonso, John K. Fraser
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Patent number: 8771678Abstract: Methods of treating patients for conditions such as breast augmentation, soft tissue defects, and urinary incontinence, are described. The methods include removing adipose tissue from a patient, processing a portion of the adipose tissue to obtain a substantially isolated population of cells comprising disaggregated adipose-derived stem cells, mixing the concentrated population of adipose-derived cells comprising disaggregated adipose-derived cells with a portion of unprocessed, intact, non-disaggregated adipose tissue to form a composition, and administering the composition to the patient from which the adipose tissue was removed.Type: GrantFiled: August 17, 2012Date of Patent: July 8, 2014Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser
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Patent number: 8691216Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.Type: GrantFiled: January 27, 2012Date of Patent: April 8, 2014Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
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Publication number: 20130121974Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: ApplicationFiled: December 21, 2012Publication date: May 16, 2013Applicant: CYTORI THERAPEUTICS, INC.Inventor: CYTORI THERAPEUTICS, INC.