Patents Assigned to Cytori Therapeutics, Inc.
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Patent number: 7901672Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: September 20, 2010Date of Patent: March 8, 2011Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick
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Publication number: 20110045959Abstract: The count of cells that are to be concentrated in a centrifugal container and transplanted can be measured without damaging these cells. Disclosed is a cell processing device comprising: a centrifugal separator which concentrates cells by rotating a centrifugal container that contains a cell suspension yielded by digestion of a biological tissue; a property detection unit which detects a property of the cell suspension contained in the centrifugal container of the centrifugal separator; and a cell count enumeration unit which calculates the cell count on the basis of the property of the cell suspension detected by the property detection unit.Type: ApplicationFiled: August 11, 2010Publication date: February 24, 2011Applicants: OLYMPUS CORPORATION, CYTORI THERAPEUTICS, INC.Inventors: Kyohei KURIHARA, Douglas M. ARM, Robert K. SHANAHAN, Lucas V. FORNACE
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Patent number: 7887795Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: September 20, 2010Date of Patent: February 15, 2011Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick
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Publication number: 20110003388Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: ApplicationFiled: September 20, 2010Publication date: January 6, 2011Applicant: CYTORI THERAPEUTICS, INC.Inventors: John K. Fraser, Marc H. Hedrick
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Publication number: 20100330673Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: ApplicationFiled: September 20, 2010Publication date: December 30, 2010Applicant: CYTORI THERAPEUTICS, INC.Inventors: John K. Fraser, Marc H. Hedrick
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Publication number: 20100303774Abstract: Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, regenerative cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic musculoskeletal benefit.Type: ApplicationFiled: August 9, 2010Publication date: December 2, 2010Applicant: CYTORI THERAPEUTICS, INC.Inventors: Marc H. Hedrick, John K. Fraser, Susan Lynn Riley, Ronda Elizabeth Schreiber
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Patent number: 7771716Abstract: Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, regenerative cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic musculoskeletal benefit.Type: GrantFiled: July 1, 2004Date of Patent: August 10, 2010Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser, Susan Lynn Riley, Ronda Elizabeth Schreiber
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Publication number: 20100136689Abstract: A biological tissue is decomposed in a short time, and cells are obtained at a high yield without interfering with the health of the cells obtained through the decomposition. There is provided a method for decomposing biological tissue which decomposes a biological tissue under an action of a digestive enzyme, wherein a digestive juice containing the digestive enzyme is additionally supplied with the digestive enzyme either continuously or stepwisely over a predetermined time within a period from start of the decomposition until termination of the decomposition while the biological tissue is being immersed in the digestive juice.Type: ApplicationFiled: May 9, 2008Publication date: June 3, 2010Applicants: OLYMPUS CORPORATION, CYTORI THERAPEUTICS, INC.Inventor: Hiroki Tsuchida
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Publication number: 20100120148Abstract: A biological tissue is decomposed in a short time, and cells are obtained at a high yield without interfering with the health of cells obtained through the decomposition. There is provided a method for decomposing biological tissue which decomposes a biological tissue under an action of a digestive enzyme, comprising: a decomposition starting step S32 of starting the decomposition of the biological tissue by immersing the biological tissue in a digestive juice having the digestive enzyme mixed in a solvent; and an enzyme concentration reduction step S31 of reducing a concentration of the digestive enzyme in the digestive juice at a predetermined timing after the start of the decomposition.Type: ApplicationFiled: May 9, 2008Publication date: May 13, 2010Applicants: OLYMPUS CORPORATION, CYTORI THERAPEUTICS, INC.Inventor: Hiroki Tsuchida
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Patent number: 7687059Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: October 20, 2006Date of Patent: March 30, 2010Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick
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Patent number: 7651684Abstract: Methods of treating patients for conditions such as breast augmentation, soft tissue defects, and urinary incontinence, are described. The methods include removing adipose tissue from a patient, processing a portion of the adipose tissue to obtain a substantially isolated population of regenerative cells, mixing the regenerative cells with another portion of adipose tissue to form a composition, and administering the composition to the patient from which the adipose tissue was removed.Type: GrantFiled: June 18, 2004Date of Patent: January 26, 2010Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser
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Publication number: 20090304644Abstract: The invention provides methods for manipulating regenerative cells from adipose tissue. Specifically, it provides methods for enrichment of desired cells and enhancement of their therapeutic effects.Type: ApplicationFiled: May 30, 2006Publication date: December 10, 2009Applicant: CYTORI THERAPEUTICS, INC.Inventors: Marc H. Hedrick, John K. Fraser
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Patent number: 7595043Abstract: The present invention relates to a device comprising a cell carrier portion containing regenerative cells, e.g., stem and progenitor cells, and a cell carrier containment portion. The device is useful for the treatment of bone related disorders, including spinal fusion related disorders and long bone or flat bone related defects. The device may be used in conjunction with disclosed automated systems and methods for separating and concentrating regenerative cells.Type: GrantFiled: July 1, 2004Date of Patent: September 29, 2009Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser, Susan Lynn Riley, Joseph W. Tai
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Patent number: 7585670Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.Type: GrantFiled: July 2, 2004Date of Patent: September 8, 2009Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Ronda Elizabeth Schreiber, Isabella Wulur
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Patent number: 7514075Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.Type: GrantFiled: June 25, 2004Date of Patent: April 7, 2009Assignee: Cytori Therapeutics, Inc.Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Robert K. Shanahan
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Patent number: 7501115Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: July 7, 2003Date of Patent: March 10, 2009Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick
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Patent number: 7473420Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: July 7, 2003Date of Patent: January 6, 2009Assignee: Cytori Therapeutics, Inc.Inventors: John K Fraser, Marc H. Hedrick
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Patent number: 7429488Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: July 7, 2003Date of Patent: September 30, 2008Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick
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Patent number: 7390484Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.Type: GrantFiled: July 7, 2003Date of Patent: June 24, 2008Assignee: Cytori Therapeutics, Inc.Inventors: John K. Fraser, Marc H. Hedrick
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Publication number: 20060204556Abstract: Cell-loaded devices or prostheses having various applications such as insertion into body passages are disclosed. The prostheses include cell carrier portions which are compatible with living tissue and which are loaded with therapeutic cell populations, and the prostheses can be applied within or replace one or more of narrow segments, environments which may be difficult to access or luminal areas of the body such as parts of blood vessels. In the context of blood vessels, the cell-loaded devices or prostheses can line or otherwise treat with therapeutic cell populations inner walls of damaged blood vessels and surrounding parenchyma or other organs.Type: ApplicationFiled: December 22, 2005Publication date: September 14, 2006Applicant: Cytori Therapeutics, Inc.Inventors: Eric Daniels, Brian Strem, Susan Riley, Mike De Emedio, John Fraser, Marc Hedrick